This package provides a set of functions to select the optimal block-length for a dependent bootstrap (block-bootstrap). Includes the Hall, Horowitz, and Jing (1995) <doi:10.1093/biomet/82.3.561> subsampling-based cross-validation method, the Politis and White (2004) <doi:10.1081/ETC-120028836> Spectral Density Plug-in method, including the Patton, Politis, and White (2009) <doi:10.1080/07474930802459016> correction, and the Lahiri, Furukawa, and Lee (2007) <doi:10.1016/j.stamet.2006.08.002> nonparametric plug-in method, with a corresponding set of S3 plot methods.

This package provides functions for the estimation of conditional copulas models, various estimators of conditional Kendall's tau (proposed in Derumigny and Fermanian (2019a, 2019b, 2020) <doi:10.1515/demo-2019-0016>, <doi:10.1016/j.csda.2019.01.013>, <doi:10.1016/j.jmva.2020.104610>), test procedures for the simplifying assumption (proposed in Derumigny and Fermanian (2017) <doi:10.1515/demo-2017-0011> and Derumigny, Fermanian and Min (2022) <doi:10.1002/cjs.11742>), and measures of non-simplifyingness (proposed in Derumigny (2025) <doi:10.48550/arXiv.2504.07704>).

This package creates a HTML widget which displays the results of searching for a pattern in files in a given folder. The results can be viewed in the RStudio viewer pane, included in a R Markdown document or in a Shiny application. Also provides a Shiny application allowing to run this widget and to navigate in the files found by the search. Instead of creating a HTML widget, it is also possible to get the results of the search in a tibble'. The search is performed by the grep command-line utility.

Fits look-up tables by filling entries with the mean or median values of observations fall in partitions of the feature space. Partitions can be determined by user of the package using input argument feature.boundaries, and dimensions of the feature space can be any combination of continuous and categorical features provided by the data set. A Predict function directly fetches corresponding entry value, and a default value is defined as the mean or median of all available observations. The table and other components are represented using the S4 class lookupTable.

This package provides tools to generate random landscape graphs, evaluate species occurrence in dynamic landscapes, simulate future landscape occupation and evaluate range expansion when new empty patches are available (e.g. as a result of climate change). References: Mestre, F., Canovas, F., Pita, R., Mira, A., Beja, P. (2016) <doi:10.1016/j.envsoft.2016.03.007>; Mestre, F., Risk, B., Mira, A., Beja, P., Pita, R. (2017) <doi:10.1016/j.ecolmodel.2017.06.013>; Mestre, F., Pita, R., Mira, A., Beja, P. (2020) <doi:10.1186/s12898-019-0273-5>.

An implementation of the Likelihood ratio Test (LRT) for testing that, in a (non)linear mixed effects model, the variances of a subset of the random effects are equal to zero. There is no restriction on the subset of variances that can be tested: for example, it is possible to test that all the variances are equal to zero. Note that the implemented test is asymptotic. This package should be used on model fits from packages nlme', lmer', and saemix'. Charlotte Baey and Estelle Kuhn (2019) <doi:10.18637/jss.v107.i06>.

Animalcules is an R package for utilizing up-to-date data analytics, visualization methods, and machine learning models to provide users an easy-to-use interactive microbiome analysis framework. It can be used as a standalone software package or users can explore their data with the accompanying interactive R Shiny application. Traditional microbiome analysis such as alpha/beta diversity and differential abundance analysis are enhanced, while new methods like biomarker identification are introduced by animalcules. Powerful interactive and dynamic figures generated by animalcules enable users to understand their data better and discover new insights.

This variant of the Racket BC (``before Chez'' or ``bytecode'') implementation is not recommended for general use. It uses CGC (a ``Conservative Garbage Collector''), which was succeeded as default in PLT Scheme version 370 (which translates to 3.7 in the current versioning scheme) by the 3M variant, which in turn was succeeded in version 8.0 by the Racket CS implementation.

Racket CGC is primarily used for bootstrapping Racket BC [3M]. It may also be used for embedding applications without the annotations needed in C code to use the 3M garbage collector.

MotifPeeker is used to compare and analyse datasets from epigenomic profiling methods with motif enrichment as the key benchmark. The package outputs an HTML report consisting of three sections: (1. General Metrics) Overview of peaks-related general metrics for the datasets (FRiP scores, peak widths and motif-summit distances). (2. Known Motif Enrichment Analysis) Statistics for the frequency of user-provided motifs enriched in the datasets. (3. De-Novo Motif Enrichment Analysis) Statistics for the frequency of de-novo discovered motifs enriched in the datasets and compared with known motifs.

This package implements the algorithm described in Trapnell,C. et al. (2010) <doi: 10.1038/nbt.1621>. This function takes read counts matrix of RNA-Seq data, feature lengths which can be retrieved using biomaRt package, and the mean fragment lengths which can be calculated using the CollectInsertSizeMetrics(Picard) tool. It then returns a matrix of FPKM normalised data by library size and feature effective length. It also provides the user with a quick and reliable function to generate FPKM heatmap plot of the highly variable features in RNA-Seq dataset.

Supports simulating choice experiment data for given designs. It helps to quickly test different designs against each other and compare the performance of new models. The goal of simulateDCE is to make it easy to simulate choice experiment datasets using designs from NGENE', idefix or spdesign'. You have to store the design file(s) in a sub-directory and need to specify certain parameters and the utility functions for the data generating process. For more details on choice experiments see Mariel et al. (2021) <doi:10.1007/978-3-030-62669-3>.

From output files obtained from the software ModestR', the relative contribution of factors to explain species distribution is depicted using several plots. A global geographic raster file for each environmental variable may be also obtained with the mean relative contribution, considering all species present in each raster cell, of the factor to explain species distribution. Finally, for each variable it is also possible to compare the frequencies of any variable obtained in the cells where the species is present with the frequencies of the same variable in the cells of the extent.

This package provides the core framework for a discrete event system to implement a complete data-to-decisions, reproducible workflow. The core components facilitate the development of modular pieces, and enable the user to include additional functionality by running user-built modules. Includes conditional scheduling, restart after interruption, packaging of reusable modules, tools for developing arbitrary automated workflows, automated interweaving of modules of different temporal resolution, and tools for visualizing and understanding the within-project dependencies. The suggested package NLMR can be installed from the repository (<https://PredictiveEcology.r-universe.dev>).

Interactive adverse event (AE) volcano plot for monitoring clinical trial safety. This tool allows users to view the overall distribution of AEs in a clinical trial using standard (e.g. MedDRA preferred term) or custom (e.g. Gender) categories using a volcano plot similar to proposal by Zink et al. (2013) <doi:10.1177/1740774513485311>. This tool provides a stand-along shiny application and flexible shiny modules allowing this tool to be used as a part of more robust safety monitoring framework like the Shiny app from the safetyGraphics R package.

This package implements quantile smoothing. It contains a dataset used to produce human chromosomal ideograms for plotting purposes and a collection of arrays that contains data of chromosome 14 of 3 colorectal tumors. The package provides functions for painting chromosomal icons, chromosome or chromosomal idiogram and other types of plots. Quantsmooth offers options like converting chromosomal ids to their numeric form, retrieving the human chromosomal length from NCBI data, retrieving regions of interest in a vector of intensities using quantile smoothing, determining cytoband position based on the location of the probe, and other useful tools.

Includes functions to estimate production frontiers and make ideal output predictions in the Data Envelopment Analysis (DEA) context using both standard models from DEA and Free Disposal Hull (FDH) and boosting techniques. In particular, EATBoosting (Guillen et al., 2023 <doi:10.1016/j.eswa.2022.119134>) and MARSBoosting. Moreover, the package includes code for estimating several technical efficiency measures using different models such as the input and output-oriented radial measures, the input and output-oriented Russell measures, the Directional Distance Function (DDF), the Weighted Additive Measure (WAM) and the Slacks-Based Measure (SBM).

This package provides a wrapper on top of the Domino Data Python SDK library. It lets you query and access Domino Data Sources directly from your R environment. Under the hood, Domino Data R SDK leverages the API provided by the Domino Data Python SDK', which must be installed as a prerequisite. Domino is a platform that makes it easy to run your code on scalable hardware, with integrated version control and collaboration features designed for analytical workflows. See <https://docs.dominodatalab.com/en/latest/api_guide/140b48/domino-data-api> for more information.

Several multivariate techniques from a biplot perspective. It is the translation (with many improvements) into R of the previous package developed in Matlab'. The package contains some of the main developments of my team during the last 30 years together with some more standard techniques. Package includes: Classical Biplots, HJ-Biplot, Canonical Biplots, MANOVA Biplots, Correspondence Analysis, Canonical Correspondence Analysis, Canonical STATIS-ACT, Logistic Biplots for binary and ordinal data, Multidimensional Unfolding, External Biplots for Principal Coordinates Analysis or Multidimensional Scaling, among many others. References can be found in the help of each procedure.

The primary function makeCPMSampler() generates a sampler function which performs the correlated pseudo-marginal method of Deligiannidis, Doucet and Pitt (2017) <arXiv:1511.04992>. If the rho= argument of makeCPMSampler() is set to 0, then the generated sampler function performs the original pseudo-marginal method of Andrieu and Roberts (2009) <DOI:10.1214/07-AOS574>. The sampler function is constructed with the user's choice of prior, parameter proposal distribution, and the likelihood approximation scheme. Note that this algorithm is not automatically tuned--each one of these arguments must be carefully chosen.

Classical Ising Model is a land mark system in statistical physics.The model explains the physics of spin glasses and magnetic materials, and cooperative phenomenon in general, for example phase transitions and neural networks.This package provides utilities to simulate one dimensional Ising Model with Metropolis and Glauber Monte Carlo with single flip dynamics in periodic boundary conditions. Utility functions for exact solutions are provided. Such as transfer matrix for 1D. Utility functions for exact solutions are provided. Example use cases are as follows: Measuring effective ergodicity and power-laws in so called functional-diffusion.

This package provides a clustering algorithm similar to K-Means is implemented, it has two main advantages, namely (a) The estimator is resistant to outliers, that means that results of estimator are still correct when there are atypical values in the sample and (b) The estimator is efficient, roughly speaking, if there are no outliers in the sample, results will be similar to those obtained by a classic algorithm (K-Means). Clustering procedure is carried out by minimizing the overall robust scale so-called tau scale. (see Gonzalez, Yohai and Zamar (2019) <arxiv:1906.08198>).

This package performs hybrid multiple testing that incorporates method selection and assumption evaluations into the analysis using EBP estimates obtained by Grenander density estimation. For instance, for 3-group comparison analysis, Hybrid Multiple testing considers EBPs as weighted EBPs between F-test and H-test with EBPs from Shapiro Wilk test of normality as weight. Instead of just using EBPs from F-test only or using H-test only, this methodology combines both types of EBPs through EBPs from Shapiro Wilk test of normality. This methodology uses then the law of total EBPs.

seq.hotSPOT provides a resource for designing effective sequencing panels to help improve mutation capture efficacy for ultradeep sequencing projects. Using SNV datasets, this package designs custom panels for any tissue of interest and identify the genomic regions likely to contain the most mutations. Establishing efficient targeted sequencing panels can allow researchers to study mutation burden in tissues at high depth without the economic burden of whole-exome or whole-genome sequencing. This tool was developed to make high-depth sequencing panels to study low-frequency clonal mutations in clinically normal and cancerous tissues.

Computing comorbidity indices and scores such as the weighted Charlson score (Charlson, 1987 <doi:10.1016/0021-9681(87)90171-8>) and the Elixhauser comorbidity score (Elixhauser, 1998 <doi:10.1097/00005650-199801000-00004>) using ICD-9-CM or ICD-10 codes (Quan, 2005 <doi:10.1097/01.mlr.0000182534.19832.83>). Australian and Swedish modifications of the Charlson Comorbidity Index are available as well (Sundararajan, 2004 <doi:10.1016/j.jclinepi.2004.03.012> and Ludvigsson, 2021 <doi:10.2147/CLEP.S282475>), together with different weighting algorithms for both the Charlson and Elixhauser comorbidity scores.