This package implements a generalized linear model approach for detecting differentially expressed genes across treatment groups in count data. The package supports both quasi-Poisson and negative binomial models to handle over-dispersion, ensuring robust identification of differential expression. It allows for the inclusion of treatment effects and gene-wise covariates, as well as normalization factors for accurate scaling across samples. Additionally, it incorporates statistical significance testing with options for p-value adjustment and log2 fold range thresholds, making it suitable for RNA-seq analysis as described in by Xu et al., (2024) <doi:10.1371/journal.pone.0300565>.

This package provides tools for differentially private principal component analysis (PCA) visualization. It includes functions for estimating private principal component directions, constructing private scree and proportion of variance explained summaries, and visualizing two-dimensional PCA score summaries using additive and sparse histogram mechanisms. Group-wise score visualizations and an interactive shiny app are also provided. Private principal component directions are based on Kim and Jung (2025) <doi:10.1002/sam.70053>. Private scree summaries use mechanisms motivated by Dwork and Roth (2014) <doi:10.1561/0400000042>, Ramsay and Spicker (2025) <doi:10.48550/arXiv.2501.14095>, and Yu, Ren and Zhou (2024) <doi:10.3150/23-BEJ1706>. Private score plot frames use smooth sensitivity quantiles from Nissim, Raskhodnikova and Smith (2007) <doi:10.1145/1250790.1250803>. Private score histograms use additive and sparse histogram ideas from Wasserman and Zhou (2010) <doi:10.1198/jasa.2009.tm08651> and Karwa and Vadhan (2018) <doi:10.4230/LIPIcs.ITCS.2018.44>.

Overload utils::'? to build unary and binary operators from existing functions, piping operators of different precedence, and flexible syntaxes.

Perform data quality assessment ('DQA') of electronic health records ('EHR'). Publication: Kapsner et al. (2021) <doi:10.1055/s-0041-1733847>.

This package provides an R interface to the Drogon high-performance C++ HTTP server framework (<https://github.com/drogonframework/drogon>). Offers a plumber'-style application programming interface for building REST services from R with substantially higher throughput.

This package provides a modern R binding for DataTables V2 with modular extension loading, Bootstrap 5 styling, Shiny integration (proxy, events, inline inputs), server-side processing helpers, and standalone (non-Shiny) support. Configure DataTables options directly via R lists, a 1:1 mapping to the JavaScript API.

This package provides a comprehensive framework for early epidemic detection through school absenteeism surveillance. The package offers three core functionalities: (1) simulation of population structures, epidemic spread, and resulting school absenteeism patterns; (2) implementation of surveillance models that generate alerts for impending epidemics based on absenteeism data and (3) evaluation of alert timeliness and accuracy through alert time quality metrics to optimize model parameters. These tools enable public health officials and researchers to develop and assess early warning systems before implementation. Methods are based on research published in Vanderkruk et al. (2023) <doi:10.1186/s12889-023-15747-z> and Ward et al. (2019) <doi:10.1186/s12889-019-7521-7>.

Computes small-sample degrees of freedom adjustment for heteroskedasticity robust standard errors, and for clustered standard errors in linear regression. See Imbens and Kolesár (2016) <doi:10.1162/REST_a_00552> for a discussion of these adjustments.

This package contains the support functions for the Time Series Analysis book. We present a function to calculate MSE and MAE for inputs of actual and forecast values. We also have the code for disaggregation as found in Wei and Stram (1990, <doi:10.1111/j.2517-6161.1990.tb01799.x>), and Hodgess and Wei (1996, "Temporal Disaggregation of Time Series").

This package implements a flexible, versatile, and computationally tractable model for density regression based on a single-weights dependent Dirichlet process mixture of normal distributions model for univariate continuous responses. The model assumes an additive structure for the mean of each mixture component and the effects of continuous covariates are captured through smooth nonlinear functions. The key components of our modelling approach are penalised B-splines and their bivariate tensor product extension. The proposed method can also easily deal with parametric effects of categorical covariates, linear effects of continuous covariates, interactions between categorical and/or continuous covariates, varying coefficient terms, and random effects. Please see Rodriguez-Alvarez, Inacio et al. (2025) for more details.

This package provides functions to manage databases: select, update, insert, and delete records, list tables, backup tables as CSV files, and import CSV files as tables.

Decomposing value added growth into explanatory factors. A cost constrained value added function is defined to specify the production frontier. Industry estimates can also be aggregated using a weighted average approach. Details about the methodology and data can be found in Diewert and Fox (2018) <doi:10.1093/oxfordhb/9780190226718.013.19> and Zeng, Parsons, Diewert and Fox (2018) <https://www.business.unsw.edu.au/research-site/centreforappliedeconomicresearch-site/Documents/emg2018-6_SZeng_EMG-Slides.pdf>.

S3 classes for multivariate optimization using the desirability function by Derringer and Suich (1980).

Calculate adjusted means and proportions of a variable by groups defined by another variable by direct standardisation, standardised to the structure of the dataset.

Base DataSHIELD functions for the client side. DataSHIELD is a software package which allows you to do non-disclosive federated analysis on sensitive data. DataSHIELD analytic functions have been designed to only share non disclosive summary statistics, with built in automated output checking based on statistical disclosure control. With data sites setting the threshold values for the automated output checks. For more details, see citation('dsBaseClient').

Adds section-aware roadmap footers to Reveal.js slide decks created with Quarto or R Markdown'. The footer highlights completed, current, and upcoming sections as slides advance. Supports multiple visual styles, inherited section tags, roadmap-free slides, and configurable colors, size, and positioning options.

Statistical hypothesis testing using the Delta method as proposed by Deng et al. (2018) <doi:10.1145/3219819.3219919>. This method replaces the standard variance estimation formula in the Z-test with an approximate formula derived via the Delta method, which can account for within-user correlation.

This package provides a wrapper on top of the Domino Data Python SDK library. It lets you query and access Domino Data Sources directly from your R environment. Under the hood, Domino Data R SDK leverages the API provided by the Domino Data Python SDK', which must be installed as a prerequisite. Domino is a platform that makes it easy to run your code on scalable hardware, with integrated version control and collaboration features designed for analytical workflows. See <https://docs.dominodatalab.com/en/latest/api_guide/140b48/domino-data-api> for more information.

Implement dynamic linear models outlined in Shumway and Stoffer (2025) <doi:10.1007/978-3-031-70584-7>. Two model structures for data smoothing and forecasting are considered. The specific models proposed will be added once the manuscript is published.

This package provides a set of three two-census methods to the estimate the degree of death registration coverage for a population. Implemented methods include the Generalized Growth Balance method (GGB), the Synthetic Extinct Generation method (SEG), and a hybrid of the two, GGB-SEG. Each method offers automatic estimation, but users may also specify exact parameters or use a graphical interface to guess parameters in the traditional way if desired.

Statistical modelling and forecasting in claims reserving in non-life insurance under the Double Chain Ladder framework by Martinez-Miranda, Nielsen and Verrall (2012).

S4-classes for setting up a coherent framework for simulation within the distr family of packages.

Finds regular and chaotic intervals in the data using the 0-1 test for chaos proposed by Gottwald and Melbourne (2004) <DOI:10.1137/080718851>.

Model-based methods for the detection of disease clusters using GLMs, GLMMs and zero-inflated models. These methods are described in V. Gómez-Rubio et al. (2019) <doi:10.18637/jss.v090.i14> and V. Gómez-Rubio et al. (2018) <doi:10.1007/978-3-030-01584-8_1>.