The IntCal20 radiocarbon calibration curves (Reimer et al. 2020 <doi:10.1017/RDC.2020.68>) are provided here in a single data package, together with previous IntCal curves (IntCal13, IntCal09, IntCal04, IntCal98) and postbomb curves. Also provided are functions to copy the curves into memory, and to plot the curves and their underlying data, as well as functions to calibrate radiocarbon dates.

This package provides a set of functions to run simple and composite box-models to describe the dynamic or static distribution of stable isotopes in open or closed systems. The package also allows the sweeping of many parameters in both static and dynamic conditions. The mathematical models used in this package are derived from Albarede, 1995, Introduction to Geochemical Modelling, Cambridge University Press, Cambridge <doi:10.1017/CBO9780511622960>.

This package provides functions that allow for convenient working with vector space models of semantics/distributional semantic models/word embeddings. Originally built for LSA models (hence the name), but can be used for all such vector-based models. For actually building a vector semantic space, use the package lsa or other specialized software. Downloadable semantic spaces can be found at <https://sites.google.com/site/fritzgntr/software-resources>.

This package provides a lasso-based method for building mechanistic models using the SAMBA algorithm (Stochastic Approximation for Model Building Algorithm) (M Prague, M Lavielle (2022) <doi:10.1002/psp4.12742>). The package extends the Rsmlx package (version 2024.1.0) to better handle high-dimensional data. It relies on the Monolix software (version 2024R1; see (<https://monolixsuite.slp-software.com/monolix/2024R1/>), which must be installed beforehand.

This package provides a collection of tools for interactive manipulation of (spatial) data layers on leaflet web maps. Tools include editing of existing layers, creation of new layers through drawing of shapes (points, lines, polygons), deletion of shapes as well as cutting holes into existing shapes. Provides control over options to e.g. prevent self-intersection of polygons and lines or to enable/disable snapping to align shapes.

Estimate genetic linkage maps for markers on a single chromosome (or in a single linkage group) from pairwise recombination fractions or intermarker distances using weighted metric multidimensional scaling. The methods are suitable for autotetraploid as well as diploid populations. Options for assessing the fit to a known map are also provided. Methods are discussed in detail in Preedy and Hackett (2016) <doi:10.1007/s00122-016-2761-8>.

Estimate Multidimensional Poverty Indices disaggregated by population subgroups based on the Alkire and Foster method (2011) <doi:10.1016/j.jpubeco.2010.11.006>. This includes the calculation of standard errors and confidence intervals. Other partial indices such as incidence, intensity and indicator-specific measures as well as intertemporal changes analysis can also be estimated. The standard errors and confidence intervals are calculated considering the complex survey design.

Basic functions to fit and predict periodic autoregressive time series models. These models are discussed in the book P.H. Franses (1996) "Periodicity and Stochastic Trends in Economic Time Series", Oxford University Press. Data set analyzed in that book is also provided. NOTE: the package was orphaned during several years. It is now only maintained, but no major enhancements are expected, and the maintainer cannot provide any support.

Designed for prediction error estimation through resampling techniques, possibly accelerated by parallel execution on a compute cluster. Newly developed model fitting routines can be easily incorporated. Methods used in the package are detailed in Porzelius Ch., Binder H. and Schumacher M. (2009) <doi:10.1093/bioinformatics/btp062> and were used, for instance, in Porzelius Ch., Schumacher M.and Binder H. (2011) <doi:10.1007/s00180-011-0236-6>.

This package provides a collection of functions for modelling mutations in pedigrees with marker data, as used e.g. in likelihood computations with microsatellite data. Implemented models include equal, proportional and stepwise models, as well as random models for experimental work, and custom models allowing the user to apply any valid mutation matrix. Allele lumping is done following the lumpability criteria of Kemeny and Snell (1976), ISBN:0387901922.

The base R data.frame, like any vector, is copied upon modification. This behavior is at odds with that of GUIs and interactive graphics. To rectify this, plumbr provides a mutable, dynamic tabular data model. Models may be chained together to form the complex plumbing necessary for sophisticated graphical interfaces. Also included is a general framework for linking datasets; an typical use case would be a linked brush.

This package performs genomic prediction of hybrid performance using eight statistical methods including GBLUP, BayesB, RKHS, PLS, LASSO, EN, LightGBM and XGBoost along with additive and additive-dominance models. Users are able to incorporate parental phenotypic information in all methods based on their specific needs. (Xu S et al(2017) <doi:10.1534/g3.116.038059>; Xu Y et al (2021) <doi: 10.1111/pbi.13458>).

An efficient tool designed for differential analysis of large-scale RNA sequencing (RNAseq) data and Bisulfite sequencing (BSseq) data in the presence of individual relatedness and population structure. PQLseq first fits a Generalized Linear Mixed Model (GLMM) with adjusted covariates, predictor of interest and random effects to account for population structure and individual relatedness, and then performs Wald tests for each gene in RNAseq or site in BSseq.

This package provides functions for interacting directly with the Quandl API to offer data in a number of formats usable in R, downloading a zip with all data from a Quandl database, and the ability to search. This R package uses the Quandl API. For more information go to <https://docs.quandl.com>. For more help on the package itself go to <https://www.quandl.com/tools/r>.

This package provides functionality for working with tensors, alternating forms, wedge products, Stokes's theorem, and related concepts from the exterior calculus. Uses disordR discipline (Hankin, 2022, <doi:10.48550/arXiv.2210.03856>). The canonical reference would be M. Spivak (1965, ISBN:0-8053-9021-9) "Calculus on Manifolds". To cite the package in publications please use Hankin (2022) <doi:10.48550/arXiv.2210.17008>.

Toolkit to support and perform discrete event simulations without resource constraints in the context of health technology assessments (HTA). The package focuses on cost-effectiveness modelling and aims to be submission-ready to relevant HTA bodies in alignment with NICE TSD 15 <https://sheffield.ac.uk/nice-dsu/tsds/patient-level-simulation>. More details an examples can be found in the package website <https://jsanchezalv.github.io/WARDEN/>.

AbSeq is a comprehensive bioinformatic pipeline for the analysis of sequencing datasets generated from antibody libraries and abseqR is one of its packages. AbseqR empowers the users of abseqPy with plotting and reporting capabilities and allows them to generate interactive HTML reports for the convenience of viewing and sharing with other researchers. Additionally, abseqR extends abseqPy to compare multiple repertoire analyses and perform further downstream analysis on its output.

This package is focused on finding differential exon usage using RNA-seq exon counts between samples with different experimental designs. It provides functions that allows the user to make the necessary statistical tests based on a model that uses the negative binomial distribution to estimate the variance between biological replicates and generalized linear models for testing. The package also provides functions for the visualization and exploration of the results.

This package includes functions and reference data to generate and manipulate log-ratios (also known as log size index (LSI) values) from measurements obtained on zooarchaeological material. Log ratios are used to compare the relative (rather than the absolute) dimensions of animals from archaeological contexts. The zoolog package is also able to seamlessly integrate data and references with heterogeneous nomenclature, which is internally managed by a zoolog thesaurus.

Offers a set of functions to easily make predictions for univariate time series. autoTS is a wrapper of existing functions of the forecast and prophet packages, harmonising their outputs in tidy dataframes and using default values for each. The core function getBestModel() allows the user to effortlessly benchmark seven algorithms along with a bagged estimator to identify which one performs the best for a given time series.

Bayesian inference using the no-U-turn (NUTS) algorithm by Hoffman and Gelman (2014) <https://www.jmlr.org/papers/v15/hoffman14a.html>. Designed for AD Model Builder ('ADMB') models, or when R functions for log-density and log-density gradient are available, such as Template Model Builder models and other special cases. Functionality is similar to Stan', and the rstan and shinystan packages are used for diagnostics and inference.

Analyzes longitudinal Electronic Health Record (EHR) data with possibly informative observational time. These methods are grouped into two classes depending on the inferential task. One group focuses on estimating the effect of an exposure on a longitudinal biomarker while the other group assesses the impact of a longitudinal biomarker on time-to-diagnosis outcomes. The accompanying paper is Du et al (2024) <doi:10.48550/arXiv.2410.13113>.

This package provides models to fit the dynamics of a regulated system experiencing exogenous inputs. The underlying models use differential equations and linear mixed-effects regressions to estimate the coefficients of the equation. With them, the functions can provide an estimated signal. The package provides simulation and analysis functions and also print, summary, plot and predict methods, adapted to the function outputs, for easy implementation and presentation of results.

This package provides a computationally efficient and statistically rigorous fast Kernel Machine method for multi-kernel analysis. The approach is based on a low-rank approximation to the nuisance effect kernel matrices. The algorithm is applicable to continuous, binary, and survival traits and is implemented using the existing single-kernel analysis software SKAT and coxKM'. coxKM can be obtained from <https://github.com/lin-lab/coxKM>.