This package provides a Bayesian framework for Dynamic Energy Budget (DEB) modelling via Stan'. Implements the standard DEB model of Kooijman (2010, <doi:10.1017/CBO9780511805400>) as a state-space model with Hamiltonian Monte Carlo inference (Carpenter et al., 2017, <doi:10.18637/jss.v076.i01>). Includes individual-level growth models, growth-reproduction models, hierarchical multi-individual models with partial pooling, and toxicokinetic-toxicodynamic (TKTD) models for ecotoxicology following the DEBtox framework (Jager et al., 2006, <doi:10.1007/s10646-006-0060-x>). Supports prior specification from biological knowledge, convergence diagnostics (Vehtari et al., 2021, <doi:10.1214/20-BA1221>), posterior predictive checks, derived quantity estimation, and visualisation via ggplot2'.

Resurrects the standard plot for shapes established by the base and graphics packages. This is suited to workflows that require plotting using the established and traditional idioms of plotting spatially coincident data where it belongs. This package depends on sf and only replaces the plot method.

Select balanced and spatially balanced probability samples in multi-dimensional spaces with any prescribed inclusion probabilities. It contains fast (C++ via Rcpp) implementations of the included sampling methods. The local pivotal method by Grafström, Lundström and Schelin (2012) <doi:10.1111/j.1541-0420.2011.01699.x> and spatially correlated Poisson sampling by Grafström (2012) <doi:10.1016/j.jspi.2011.07.003> are included. Also the cube method (for balanced sampling) and the local cube method (for doubly balanced sampling) are included, see Grafström and Tillé (2013) <doi:10.1002/env.2194>.

This package contains tools to fit both predictive and prognostic biomarker effects using biomarker threshold models and continuous threshold models. Evaluate the treatment effect, biomarker effect and treatment-biomarker interaction using probability index measurement. Test for treatment-biomarker interaction using residual bootstrap method.

This package provides functions for summarizing and plotting the output of the command-line tool BeXY (<https://bitbucket.org/wegmannlab/bexy>), a tool that performs Bayesian inference of sex chromosome karyotypes and sex-linked scaffolds from low-depth sequencing data.

Allows access to data from the Brazilian Public Security Information System (SINESP) by state and municipality. It should be emphasized that the package only extracts the data and facilitates its manipulation in R. Therefore, its sole purpose is to support empirical research. All data credits belong to SINESP, an integrated information platform developed and maintained by the National Secretariat of Public Security (SENASP) of the Ministry of Justice and Public Security. <https://www.gov.br/mj/pt-br/assuntos/sua-seguranca/seguranca-publica/sinesp-1>.

This package provides the bayesGARCH() function which performs the Bayesian estimation of the GARCH(1,1) model with Student's t innovations as described in Ardia (2008) <doi:10.1007/978-3-540-78657-3>.

Various tools dealing with batch effects, in particular enabling the removal of discrepancies between training and test sets in prediction scenarios. Moreover, addon quantile normalization and addon RMA normalization (Kostka & Spang, 2008) is implemented to enable integrating the quantile normalization step into prediction rules. The following batch effect removal methods are implemented: FAbatch, ComBat, (f)SVA, mean-centering, standardization, Ratio-A and Ratio-G. For each of these we provide an additional function which enables a posteriori ('addon') batch effect removal in independent batches ('test data'). Here, the (already batch effect adjusted) training data is not altered. For evaluating the success of batch effect adjustment several metrics are provided. Moreover, the package implements a plot for the visualization of batch effects using principal component analysis. The main functions of the package for batch effect adjustment are ba() and baaddon() which enable batch effect removal and addon batch effect removal, respectively, with one of the seven methods mentioned above. Another important function here is bametric() which is a wrapper function for all implemented methods for evaluating the success of batch effect removal. For (addon) quantile normalization and (addon) RMA normalization the functions qunormtrain(), qunormaddon(), rmatrain() and rmaaddon() can be used.

Verification of continually updating time series data where we expect new values, but want to ensure previous data remains unchanged. Data previously recorded could change for a number of reasons, such as discovery of an error in model code, a change in methodology or instrument recalibration. Monitoring data sources for these changes is not always possible. Other unnoticed changes could include a jump in time or measurement frequency, due to instrument failure or software updates. Functionality is provided that can be used to check and flag changes to previous data to prevent changes going unnoticed, as well as unexpected jumps in time.

Simulating synthetic clumped isotope dataset, fitting linear regression models under Bayesian and non-Bayesian frameworks, and generating temperature reconstructions for the same two approaches. Please note that models implemented in this package are described in Roman-Palacios et al. (2021) <doi:10.1002/essoar.10507995.1>.

Easy application of Bayesian inference for functional responses via brms'. This package allows to fit various FR models for single- and multi-prey experiments by providing nonlinear prediction functions for brms'. It uses dynamical prediction models to correct for prey depletion. The brms framework facilitates statistical modeling and enables users to conveniently incorporate covariates such as temperature gradients, experimental treatment variables, or random effects that account for grouping in experimental units. Default brms functions make it easy to perform model checking, model comparison and hypothesis testing. Potential statistical issues with data from feeding trials, such as overdispersion, can be resolved by effortlessly switching between likelihood functions. This package, together with its tutorials, should provide students and researchers with a comprehensive and integrated statistical framework for easily testing their hypotheses on trophic interactions. References: Rosenbaum and Rall (2018) <doi:10.1111/2041-210X.13039>; Rosenbaum et al. (2024) <doi:10.1111/2041-210X.14372>.

This package implements a Bayesian version of the general mixed Yule-coalescent model for species delimitation. It uses Markov Chain Monte Carlo simulation to evaluate the posterior distribution of the model and supports flexible prior specification on model parameters.

An R interface to the Stark-Parker implementation of an algorithm for bounded-variable least squares.

Analyze bioequivalence study data with industrial strength. The statistical core is delegated to the sasLM package, which reproduces SAS PROC GLM output; this covers the analysis of variance, the least square means, and the confidence interval of a 2x2 crossover study. Sample size could be determined for various crossover designs, such as 2x2 design, 2x4 design, 4x4 design, Balaam design, Two-sequence dual design, and William design. Reference: Chow SC, Liu JP. Design and Analysis of Bioavailability and Bioequivalence Studies. 3rd ed. (2009, ISBN:978-1-58488-668-6).

Bayesian hierarchical methods for the detection of differences in rates of related outcomes for multiple treatments for clustered observations (Carragher et al. (2020) <doi:10.1002/sim.8563>). This software was developed for the Precision Drug Theraputics: Risk Prediction in Pharmacoepidemiology project as part of a Rutherford Fund Fellowship at Health Data Research (UK), Medical Research Council (UK) award reference MR/S003967/1 (<https://gtr.ukri.org/>). Principal Investigator: Raymond Carragher.

This package provides tools designed to perform and evaluate cluster analysis (including Tocher's algorithm), discriminant analysis and path analysis (standard and under collinearity), as well as some useful miscellaneous tools for dealing with sample size and optimum plot size calculations. A test for seed sample heterogeneity is now available. Mantel's permutation test can be found in this package. A new approach for calculating its power is implemented. biotools also contains tests for genetic covariance components. Heuristic approaches for performing non-parametric spatial predictions of generic response variables and spatial gene diversity are implemented.

This package provides functions for training extreme gradient boosting model using propensity score A-learning and weight-learning methods. For further details, see Liu et al. (2024) <doi:10.1093/bioinformatics/btae592>.

An implementation of the Bayesian Surrogate Evaluation Test (BSET) for assessing the validity of surrogate markers in clinical trials. Provides hypothesis testing tools to evaluate whether a surrogate can reliably estimate the causal effect of a treatment on a primary outcome. Implements the imputation-based Bayesian methodology of Carlotti and Parast (2026) <doi:10.48550/arXiv.2603.14381>, extending the frequentist rank-based approach of Parast et al. (2024) <doi:10.1093/biomtc/ujad035>. Addresses key limitations of the frequentist method, including the lack of causal interpretability and the inability to adjust for covariates in the estimation process.

This package provides a collection of S4 classes, methods and functions to create and visualize business plans. Different types of cash flows can be defined, which can then be used and tabulated to create profit and loss statements, cash flow plans, investment and depreciation schedules, loan amortization schedules, etc. The methods are designed to produce handsome tables in both PDF and HTML using RMarkdown or Shiny'.

This package provides a maximum likelihood estimation of Bivariate Zero-Inflated Negative Binomial (BZINB) model or the nested model parameters. Also estimates the underlying correlation of the a pair of count data. See Cho, H., Liu, C., Preisser, J., and Wu, D. (In preparation) for details.

Implementation of a collection of MCMC methods for Bayesian structure learning of directed acyclic graphs (DAGs), both from continuous and discrete data. For efficient inference on larger DAGs, the space of DAGs is pruned according to the data. To filter the search space, the algorithm employs a hybrid approach, combining constraint-based learning with search and score. A reduced search space is initially defined on the basis of a skeleton obtained by means of the PC-algorithm, and then iteratively improved with search and score. Search and score is then performed following two approaches: Order MCMC, or Partition MCMC. The BGe score is implemented for continuous data and the BDe score is implemented for binary data or categorical data. The algorithms may provide the maximum a posteriori (MAP) graph or a sample (a collection of DAGs) from the posterior distribution given the data. All algorithms are also applicable for structure learning and sampling for dynamic Bayesian networks. References: J. Kuipers, P. Suter, G. Moffa (2022) <doi:10.1080/10618600.2021.2020127>, N. Friedman and D. Koller (2003) <doi:10.1023/A:1020249912095>, J. Kuipers and G. Moffa (2017) <doi:10.1080/01621459.2015.1133426>, M. Kalisch et al. (2012) <doi:10.18637/jss.v047.i11>, D. Geiger and D. Heckerman (2002) <doi:10.1214/aos/1035844981>, P. Suter, J. Kuipers, G. Moffa, N.Beerenwinkel (2023) <doi:10.18637/jss.v105.i09>.

This package provides a statistical tool to inference the multi-level partial correlations based on multi-subject time series data, especially for brain functional connectivity. It combines both individual and population level inference by using the methods of Qiu and Zhou. (2021)<DOI: 10.1080/01621459.2021.1917417> and Genovese and Wasserman. (2006)<DOI: 10.1198/016214506000000339>. It realizes two reliable estimation methods of partial correlation coefficients, using scaled lasso and lasso. It can be used to estimate individual- or population-level partial correlations, identify nonzero ones, and find out unequal partial correlation coefficients between two populations.

This package provides functions to download and work with the Bangladesh Environmental Mobility Panel (BEMP), a household panel survey tracing the impacts of riverbank erosion and flooding on (im)mobility, socio-economic outcomes, and political attitudes along the Jamuna River in Bangladesh (2021-2024). Wave datasets (20 files across 14 survey rounds) are hosted on Zenodo (<doi:10.5281/zenodo.18229497>) and downloaded on demand with local caching. Bundled data include a merged cross-wave codebook and wave metadata.

This package provides functions for downloading data from the Bank for International Settlements (BIS; <https://www.bis.org/>) in Basel. Supported are only full datasets in (typically) CSV format. The package is lightweight and without dependencies; suggested packages are used only if data is to be transformed into particular data structures, for instance into zoo objects. Downloaded data can optionally be cached, to avoid repeated downloads of the same files.