This package provides statistical methods for network meta-analysis of 1â 5 diagnostic tests to simultaneously compare multiple tests within a missing data framework, including: - Bayesian hierarchical model for network meta-analysis of multiple diagnostic tests (Ma, Lian, Chu, Ibrahim, and Chen (2018) <doi:10.1093/biostatistics/kxx025>) - Bayesian Hierarchical Summary Receiver Operating Characteristic Model for Network Meta-Analysis of Diagnostic Tests (Lian, Hodges, and Chu (2019) <doi:10.1080/01621459.2018.1476239>).

Visualization and analysis tools to aid in the interpretation of neural network models. Functions are available for plotting, quantifying variable importance, conducting a sensitivity analysis, and obtaining a simple list of model weights.

This package provides tools for visual inference. Generate null data sets and null plots using permutation and simulation. Calculate distance metrics for a lineup, and examine the distributions of metrics.

This package provides a framework for systematic exploration of association rules (Agrawal et al., 1994, <https://www.vldb.org/conf/1994/P487.PDF>), contrast patterns (Chen, 2022, <doi:10.48550/arXiv.2209.13556>), emerging patterns (Dong et al., 1999, <doi:10.1145/312129.312191>), subgroup discovery (Atzmueller, 2015, <doi:10.1002/widm.1144>), and conditional correlations (Hájek, 1978, <doi:10.1007/978-3-642-66943-9>). User-defined functions may also be supplied to guide custom pattern searches. Supports both crisp (Boolean) and fuzzy data. Generates candidate conditions expressed as elementary conjunctions, evaluates them on a dataset, and inspects the induced sub-data for statistical, logical, or structural properties such as associations, correlations, or contrasts. Includes methods for visualization of logical structures and supports interactive exploration through integrated Shiny applications.

This package contains a collection of functions for performing different kinds of calculation that are of interest to someone following a diet plan. Calculators for the Basal Metabolic Rate are based on Mifflin et al. (1990) <doi:10.1093/ajcn/51.2.241> and McArdle, W. D., Katch, F. I., & Katch, V. L. (2010, ISBN:9780812109917).

The National Ecological Observatory Network (NEON) provides access to its numerous data products through its REST API, <https://data.neonscience.org/data-api/>. This package provides a high-level user interface for downloading and storing NEON data products. Unlike neonUtilities', this package will avoid repeated downloading, provides persistent storage, and improves performance. neonstore can also construct a local duckdb database of stacked tables, making it possible to work with tables that are far to big to fit into memory.

This package contains a module to define neural networks from custom components and versions of Autoencoder, BP, LVQ, MAM NN.

Count the occurrence of sequences of values in a vector that meets certain conditions of length and magnitude. The method is based on the Run Length Encoding algorithm, available with base R, inspired by A. H. Robinson and C. Cherry (1967) <doi:10.1109/PROC.1967.5493>.

Nonparametric smoothing methods for density and regression estimation involving circular data, including the estimation of the mean regression function and other conditional characteristics.

Clinical reporting figures require to use consistent colors and configurations. As a part of the Roche open-source clinical reporting project, namely the NEST project, the nestcolor package specifies the color code and default theme with specifying ggplot2 theme parameters. Users can easily customize color and theme settings before using the reset of NEST packages to ensure consistent settings in both static and interactive output at the downstream.

This package provides tools for 4D nucleome imaging. Quantitative analysis of the 3D nuclear landscape recorded with super-resolved fluorescence microscopy. See Volker J. Schmid, Marion Cremer, Thomas Cremer (2017) <doi:10.1016/j.ymeth.2017.03.013>.

This package provides functions to compute the Rank-Based Stability Index (RSI) for genotype by environment interaction data, along with a genotype plus genotype-by-environment (GGE) style biplot visualization of stability.

Predicting the structure of a graph including new nodes and edges using a time series of graphs. Flux balance analysis, a linear and integer programming technique used in biochemistry is used with time series prediction methods to predict the graph structure at a future time point Kandanaarachchi (2025) <doi:10.48550/arXiv.2507.05806>.

An interactive document on the topic of naive Bayes classification analysis using rmarkdown and shiny packages. Runtime examples are provided in the package function as well as at <https://kartikeyab.shinyapps.io/NBShiny/>.

Generates LaTeX code for drawing well-formatted neural network diagrams with TikZ'. Users have to define number of neurons on each layer, and optionally define neuron connections they would like to keep or omit, layers they consider to be oversized and neurons they would like to draw with lighter color. They can also specify the title of diagram, color, opacity of figure, labels of layers, input and output neurons. In addition, this package helps to produce LaTeX code for drawing activation functions which are crucial in neural network analysis. To make the code work in a LaTeX editor, users need to install and import some TeX packages including TikZ in the setting of TeX file.

There are three distinct approaches for phase error correction, they are: a single linear model with a choice of optimization functions, multiple linear models with optimization function choices and a shrinkage-based method. The methodology is based on our new algorithms and various references (Binczyk et al. (2015) <doi:10.1186/1475-925X-14-S2-S5>,Chen et al. (2002) <doi:10.1016/S1090-7807(02)00069-1>, de Brouwer (2009) <doi:10.1016/j.jmr.2009.09.017>, Džakula (2000) <doi:10.1006/jmre.2000.2123>, Ernst (1969) <doi:10.1016/0022-2364(69)90003-1>, Liland et al. (2010) <doi:10.1366/000370210792434350>).

This package provides functions for manipulating nested data frames in a list-column using dplyr <https://dplyr.tidyverse.org/> syntax. Rather than unnesting, then manipulating a data frame, nplyr allows users to manipulate each nested data frame directly. nplyr is a wrapper for dplyr functions that provide tools for common data manipulation steps: filtering rows, selecting columns, summarising grouped data, among others.

This package provides an htmlwidgets <https://www.htmlwidgets.org/> interface to NGL.js <http://nglviewer.org/ngl/api/>. NGLvieweR can be used to visualize and interact with protein databank ('PDB') and structural files in R and Shiny applications. It includes a set of API functions to manipulate the viewer after creation in Shiny.

This package infers species associations from community matrices. Uses local and (optional) regional-scale co-occurrence data by comparing observed partial correlation coefficients between species to those estimated from regional species distributions. Extends Gaussian graphical models to a null modeling framework. Provides interface to a variety of inverse covariance matrix estimation methods.

This package provides a set of functions to estimate outcomes of fourth down plays in the National Football League and obtain fourth down plays from <https://www.nfl.com/> and <https://www.espn.com/>.

This package provides a nonvisual procedure for screening time series for nonstationarity in the context of intensive longitudinal designs, such as ecological momentary assessments. The method combines two diagnostics: one for detecting trends (based on the split R-hat statistic from Bayesian convergence diagnostics) and one for detecting changes in variance (a novel extension inspired by Levene's test). This approach allows researchers to efficiently and reproducibly detect violations of the stationarity assumption, especially when visual inspection of many individual time series is impractical. The procedure is suitable for use in all areas of research where time series analysis is central. For a detailed description of the method and its validation through simulations and empirical application, see Zitzmann, S., Lindner, C., Lohmann, J. F., & Hecht, M. (2024) "A Novel Nonvisual Procedure for Screening for Nonstationarity in Time Series as Obtained from Intensive Longitudinal Designs" <https://www.researchgate.net/publication/384354932_A_Novel_Nonvisual_Procedure_for_Screening_for_Nonstationarity_in_Time_Series_as_Obtained_from_Intensive_Longitudinal_Designs>.

The number of distinct alleles observed in a DNA mixture is informative of the number of contributors to the mixture. The package provides methods for computing the probability distribution of the number of distinct alleles in a mixture for a given set of allele frequencies. The mixture contributors may be related according to a provided pedigree.

Helps a clinical trial team discuss the clinical goals of a well-defined biomarker with a diagnostic, staging, prognostic, or predictive purpose. From this discussion will come a statistical plan for a (non-randomized) validation trial. Both prospective and retrospective trials are supported. In a specific focused discussion, investigators should determine the range of "discomfort" for the NNT, number needed to treat. The meaning of the discomfort range, [NNTlower, NNTupper], is that within this range most physicians would feel discomfort either in treating or withholding treatment. A pair of NNT values bracketing that range, NNTpos and NNTneg, become the targets of the study's design. If the trial can demonstrate that a positive biomarker test yields an NNT less than NNTlower, and that a negative biomarker test yields an NNT less than NNTlower, then the biomarker may be useful for patients. A highlight of the package is visualization of a "contra-Bayes" theorem, which produces criteria for retrospective case-controls studies.

The aim of nosoi (pronounced no.si) is to provide a flexible agent-based stochastic transmission chain/epidemic simulator (Lequime et al. Methods in Ecology and Evolution 11:1002-1007). It is named after the daimones of plague, sickness and disease that escaped Pandora's jar in the Greek mythology. nosoi is able to take into account the influence of multiple variable on the transmission process (e.g. dual-host systems (such as arboviruses), within-host viral dynamics, transportation, population structure), alone or taken together, to create complex but relatively intuitive epidemiological simulations.