This package provides a pipeline to annotate a number of peaks from the IDSL.IPA peaklists using an exhaustive chemical enumeration-based approach. This package can perform elemental composition calculations using the following 15 elements : C, B, Br, Cl, K, S, Si, N, H, As, F, I, Na, O, and P.

This package provides functions for the identification, classification, and ranking of influential nodes and candidate features from network and omics data. The package implements the Integrated Value of Influence (IVI) for integrative network centrality analysis, the SIR-based Influence Ranking (SIRIR) model for unsupervised influence ranking, and the Experimental data-based Integrative Ranking (ExIR) model for prioritizing candidate driver, biomarker, and mediator features from experimental omics data. Functions are provided for network reconstruction from adjacency matrices and data frames, topological analysis, centrality calculation, assessment of associations between centrality measures, and conditional probability analysis. ExIR supports bulk and single-cell omics data, including matrices, sparse matrices, data frames, tibbles, and Seurat objects.

This package implements continuous-time hidden Markov models (HMMs) to infer identity-by-descent (IBD) segments shared by two individuals. Supports two- and three-state models using single-nucleotide polymorphism (SNP) genotypes or genotype likelihoods. Provides posterior probabilities at each marker (forward-backward algorithm), prediction of IBD segments (Viterbi algorithm), and functions for visualising results. Supports both autosomal data and X-chromosomal data. The methodology and package are described in Vigeland et al. (2026) <doi:10.1016/j.fsigen.2025.103409>.

Imputation of missing values using the last observation carried forward technique on Indonesia food prices data that is time series data. Also, this technique applies imputation to data whose dates do not appear directly. So that the series assumptions in the time series data are met.

An implementation of the MaxLFQ algorithm by Cox et al. (2014) <doi:10.1074/mcp.M113.031591> in a comprehensive pipeline for processing proteomics data in data-independent acquisition mode (Pham et al. 2020 <doi:10.1093/bioinformatics/btz961>; Pham et al. 2026 <doi:10.1021/acs.jproteome.5c01038>). It offers additional options for protein quantification using the N most intense fragment ions, using all fragment ions, the median polish algorithm by Tukey (1977, ISBN:0201076160), and a robust linear model. In general, the tool can be used to integrate multiple proportional observations into a single quantitative value.

Independent vector analysis (IVA) is a blind source separation (BSS) model where several datasets are jointly unmixed. This package provides several methods for the unmixing together with some performance measures. For details, see Anderson et al. (2011) <doi:10.1109/TSP.2011.2181836> and Lee et al. (2007) <doi:10.1016/j.sigpro.2007.01.010>.

Calculate incidence and prevalence using data mapped to the Observational Medical Outcomes Partnership (OMOP) common data model. Incidence and prevalence can be estimated for the total population in a database or for a stratification cohort.

This package provides an R version of the InterVA4 software (<http://www.interva.net>) for coding cause of death from verbal autopsies. It also provides simple graphical representation of individual and population level statistics.

Geostatistical interpolation has traditionally been done by manually fitting a variogram and then interpolating. Here, we introduce classes and methods that can do this interpolation automatically. Pebesma et al (2010) gives an overview of the methods behind and possible usage <doi:10.1016/j.cageo.2010.03.019>.

Versatile tools and data for graph matching analysis with various forms of prior information that supports working with igraph objects, matrix objects, or lists of either.

This package provides a dataset of the top colours of photos from Instagram taken in 2014 in the city of Vancouver, British Columbia, Canada. It consists of: top colour and counts data. This data was obtained using the Instagram API. Instagram is a web photo sharing service. It can be found at: <https://instagram.com>. The Instagram API is documented at: <https://instagram.com/developer/>.

Implementation of methods Extremum Surface Estimator (ESE) and Extremum Distance Estimator (EDE) to identify the inflection point of a curve . Christopoulos, DT (2014) <doi:10.48550/arXiv.1206.5478> . Christopoulos, DT (2016) <https://demovtu.veltech.edu.in/wp-content/uploads/2016/04/Paper-04-2016.pdf> . Christopoulos, DT (2016) <doi:10.2139/ssrn.3043076> .

The matrix factor model has drawn growing attention for its advantage in achieving two-directional dimension reduction simultaneously for matrix-structured observations. In contrast to the Principal Component Analysis (PCA)-based methods, we propose a simple Iterative Alternating Least Squares (IALS) algorithm for matrix factor model, see the details in He et al. (2023) <arXiv:2301.00360>.

This package provides a Bayesian framework that integrates several regression models to identify a parsimonious set of biomarkers shared across disparate data platforms (for example genomic, transcriptomic and proteomic assays). Subjects are partitioned into subgroups defined by their pattern of platform availability, so that no subject with partially missing platform data is excluded, and information is borrowed across subgroups through a Markov random field prior on the variable-selection indicators together with non-local (product moment) priors on the regression effects. The methodology was introduced for time-to-event outcomes by Chekouo, Stingo, Doecke and Do (2017) <doi:10.1111/biom.12587>; this package additionally supports continuous (Gaussian) and binary (probit) outcomes. Posterior inference is carried out by a Markov chain Monte Carlo sampler implemented in C for computational efficiency.

Non-parametric resampling-based inference tests for ExPosition.

One function to read files. One function to write files. One function to direct plots to screen or file. Automatic file format inference and directory structure creation.

This package provides a model that provides researchers with a powerful tool for the classification and study of native corn by aiding in the identification of racial complexes which are fundamental to Mexico's agriculture and culture. This package has been developed based on data collected by "Proyecto Global de Maà ces Nativos México", which has conducted exhaustive surveys across the country to document the qualitative and quantitative characteristics of different types of native maize. The trained model uses a robust and diverse dataset, enabling it to achieve an 80% accuracy in classifying maize racial complexes. The characteristics included in the analysis comprise geographic location, grain and cob colors, as well as various physical measurements, such as lengths and widths.

This package provides a multi-layered untargeted pipeline for high-throughput LC/HRMS data processing to extract signals of organic small molecules. The package performs ion pairing, peak detection, peak table alignment, retention time correction, aligned peak table gap filling, peak annotation and visualization of extracted ion chromatograms (EICs) and total ion chromatograms (TICs). The IDSL.IPA package was introduced in <doi:10.1021/acs.jproteome.2c00120> .

R interface to access the Vocabularies REST API of the ICES (International Council for the Exploration of the Sea) Vocabularies database <https://vocab.ices.dk/services/>.

Generates Personality Insights sunburst diagrams based on IBM Watson Personality Insights service output.

This package contains functions for evaluating & comparing the performance of Binary classification models. Functions can be called either statically or interactively (as Shiny Apps).

This package provides a function to calculate infinite-jackknife-based standard errors for fixed effects parameters in brms models, handling both clustered and independent data. References: Ji et al. (2024) <doi:10.48550/arXiv.2407.09772>; Giordano et al. (2024) <doi:10.48550/arXiv.2305.06466>.

Up-to-date data from the Unicode CLDR Project (where CLDR stands for Common Locale Data Repository') are available here as a series of easy-to-parse datasets. Several functions are provided for extracting key elements from the tabular datasets.

This package provides a unified data layer for single-cell, spatial and bulk T-cell and B-cell immune receptor repertoire data. Think AnnData or SeuratObject, but for AIRR data, a.k.a. Adaptive Immune Receptor Repertoire, VDJ-seq, RepSeq, or VDJ sequencing data.