Computes various geospatial indices of socioeconomic deprivation and disparity in the United States. Some indices are considered "spatial" because they consider the values of neighboring (i.e., adjacent) census geographies in their computation, while other indices are "aspatial" because they only consider the value within each census geography. Two types of aspatial neighborhood deprivation indices (NDI) are available: including: (1) based on Messer et al. (2006) <doi:10.1007/s11524-006-9094-x> and (2) based on Andrews et al. (2020) <doi:10.1080/17445647.2020.1750066> and Slotman et al. (2022) <doi:10.1016/j.dib.2022.108002> who use variables chosen by Roux and Mair (2010) <doi:10.1111/j.1749-6632.2009.05333.x>. Both are a decomposition of multiple demographic characteristics from the U.S. Census Bureau American Community Survey 5-year estimates (ACS-5; 2006-2010 onward). Using data from the ACS-5 (2005-2009 onward), the package can also compute indices of racial or ethnic residential segregation, including but limited to those discussed in Massey & Denton (1988) <doi:10.1093/sf/67.2.281>, and additional indices of socioeconomic disparity.

This package performs combination tests and sample size calculation for fixed design with survival endpoints using combination tests under either proportional hazards or non-proportional hazards. The combination tests include maximum weighted log-rank test and projection test. The sample size calculation procedure is very flexible, allowing for user-defined hazard ratio function and considering various trial conditions like staggered entry, drop-out etc. The sample size calculation also applies to various cure models such as proportional hazards cure model, cure model with (random) delayed treatments effects. Trial simulation function is also provided to facilitate the empirical power calculation. The references for projection test and maximum weighted logrank test include Brendel et al. (2014) <doi:10.1111/sjos.12059> and Cheng and He (2021) <arXiv:2110.03833>. The references for sample size calculation under proportional hazard include Schoenfeld (1981) <doi:10.1093/biomet/68.1.316> and Freedman (1982) <doi:10.1002/sim.4780010204>. The references for calculation under non-proportional hazards include Lakatos (1988) <doi:10.2307/2531910> and Cheng and He (2023) <doi:10.1002/bimj.202100403>.

Lite interface for getting data from OSM service Nominatim <https://nominatim.org/release-docs/latest/>. Extract coordinates from addresses, find places near a set of coordinates and return spatial objects on sf format.

Represent network or igraph objects whose vertices can be represented by features in an sf object as a network graph surmising a sf plot. Fits into ggplot2 grammar.

Calculates network measures commonly used in Network Medicine. Measures such as the Largest Connected Component, the Relative Largest Connected Component, Proximity and Separation are calculated along with their statistical significance. Significance can be computed both using a degree-preserving randomization and non-degree preserving.

This data package contains the Item Response Theory (IRT) parameters for the National Center for Education Statistics (NCES) items used on the National Assessment of Education Progress (NAEP) from 1990 to 2015. The values in these tables are used along with NAEP data to turn student item responses into scores and include information about item difficulty, discrimination, and guessing parameter for 3 parameter logit (3PL) items. Parameters for Generalized Partial Credit Model (GPCM) items are also included. The adjustments table contains the information regarding the treatment of items (e.g., deletion of an item or a collapsing of response categories), when these items did not appear to fit the item response models used to describe the NAEP data. Transformation constants change the score estimates that are obtained from the IRT scaling program to the NAEP reporting metric. Values from the years 2000 - 2013 were taken from the NCES website <https://nces.ed.gov/nationsreportcard/> and values from 1990 - 1998 and 2015 were extracted from their NAEP data files. All subtest names were reduced and homogenized to one word (e.g. "Reading to gain information" became "information"). The various subtest names for univariate transformation constants were all homogenized to "univariate".

This package provides a nomogram, which can be carried out in rms package, provides a graphical explanation of a prediction process. However, it is not very easy to draw straight lines, read points and probabilities accurately. Even, it is hard for users to calculate total points and probabilities for all subjects. This package provides formula_rd() and formula_lp() functions to fit the formula of total points with raw data and linear predictors respectively by polynomial regression. Function points_cal() will help you calculate the total points. prob_cal() can be used to calculate the probabilities after lrm(), cph() or psm() regression. For more complex condition, interaction or restricted cubic spine, TotalPoints.rms() can be used.

We fit inverse probability weighting estimator and the augmented inverse probability weighting for non-monotone missing at random data.

This package provides a toolkit for medical records data analysis. The naryn package implements an efficient data structure for storing medical records, and provides a set of functions for data extraction, manipulation and analysis.

This allows you to generate reporting workflows around nlmixr2 analyses with outputs in Word and PowerPoint. You can specify figures, tables and report structure in a user-definable YAML file. Also you can use the internal functions to access the figures and tables to allow their including in other outputs (e.g. R Markdown).

Simple interface routines to facilitate the handling of network objects with complex intertemporal data. This is a part of the "statnet" suite of packages for network analysis.

This package implements the nonparametric trend test for one or several samples as proposed by Bathke (2009) <doi:10.1007/s00184-008-0171-x>. The method provides a unified framework for analyzing trends in both independent and dependent data samples, making it a versatile tool for various study designs. The package allows for the evaluation of different trend alternatives, including two-sided (general trend), monotonic increasing, and monotonic decreasing trends. As a nonparametric procedure, it does not require the assumption of data normality, offering a robust alternative to parametric tests.

NNS (Nonlinear Nonparametric Statistics) leverages partial moments â the fundamental elements of variance that asymptotically approximate the area under f(x) â to provide a robust foundation for nonlinear analysis while maintaining linear equivalences. NNS delivers a comprehensive suite of advanced statistical techniques, including: Numerical integration, Numerical differentiation, Clustering, Correlation, Dependence, Causal analysis, ANOVA, Regression, Classification, Seasonality, Autoregressive modeling, Normalization, Stochastic dominance and Advanced Monte Carlo sampling. All routines based on: Viole, F. and Nawrocki, D. (2013), Nonlinear Nonparametric Statistics: Using Partial Moments (ISBN: 1490523995).

This package provides routines to compute normalised prediction distribution errors, a metric designed to evaluate non-linear mixed effect models such as those used in pharmacokinetics and pharmacodynamics.

Model-based clustering of high-dimensional non-negative data that follow Generalized Negative Binomial distribution. All functions in this package applies to either continuous or integer data. Correlation between variables are allowed, while samples are assumed to be independent.

Datasets of driving offences and fines in New Zealand between 2009 and 2017. Originally published by the New Zealand Police at <http://www.police.govt.nz/about-us/publication/road-policing-driver-offence-data-january-2009-december-2017>.

This package provides streamlined installation for packages from the natverse', a suite of R packages for computational neuroanatomy built on top of the nat NeuroAnatomy Toolbox package. Installation of the complete natverse suite requires a GitHub user account and personal access token GITHUB_PAT'. natmanager will help the end user set this up if necessary.

This package provides functions for working with NHS number checksums. The UK's National Health Service issues NHS numbers to all users of its services and this package implements functions for verifying that the numbers are valid according to the checksum scheme the NHS use. Numbers can be validated and checksums created.

Fit and compare nonlinear mixed-effects models in differential equations with flexible dosing information commonly seen in pharmacokinetics and pharmacodynamics (Almquist, Leander, and Jirstrand 2015 <doi:10.1007/s10928-015-9409-1>). Differential equation solving is by compiled C code provided in the rxode2 package (Wang, Hallow, and James 2015 <doi:10.1002/psp4.12052>). This package is for support functions like preconditioned fits <doi:10.1208/s12248-016-9866-5>, boostrap and stepwise covariate selection.

Computes the probability density function, the cumulative density function, quantile function, random numbers and measures of inference for the following families exponentiated generalized gull alpha power family, exponentiated gull alpha powerfamily, gull alpha power family.

This package provides a permutation-based hypothesis test for statistical comparison of two networks based on the invariance measures of the R package NetworkComparisonTest by van Borkulo et al. (2022), <doi:10.1037/met0000476>: network structure invariance, global strength invariance, edge invariance, and various centrality measures. Edgelists from dependent or independent samples are used as input. These edgelists are generated from concept maps and summed into two comparable group networks. The networks can be directed or undirected.

Quantifies and removes technical noise from high-throughput sequencing data. Two approaches are used, one based on the count matrix, and one using the alignment BAM files directly. Contains several options for every step of the process, as well as tools to quality check and assess the stability of output.

Design and analysis of flexible platform trials with non-concurrent controls. Functions for data generation, analysis, visualization and running simulation studies are provided. The implemented analysis methods are described in: Bofill Roig et al. (2022) <doi:10.1186/s12874-022-01683-w>, Saville et al. (2022) <doi:10.1177/17407745221112013> and Schmidli et al. (2014) <doi:10.1111/biom.12242>.

Greedy Bayesian algorithm to fit the noisy stochastic block model to an observed sparse graph. Moreover, a graph inference procedure to recover Gaussian Graphical Model (GGM) from real data. This procedure comes with a control of the false discovery rate. The method is described in the article "Enhancing the Power of Gaussian Graphical Model Inference by Modeling the Graph Structure" by Kilian, Rebafka, and Villers (2024) <arXiv:2402.19021>.