The goal of gnonadd is to simplify workflows in the analysis of non-additive effects of sequence variants. This includes variance effects (Ivarsdottir et. al (2017) <doi:10.1038/ng.3928>), correlation effects, interaction effects and dominance effects. The package also includes convenience functions for visualization.

This package provides tools for fitting statistical network models to dynamic network data. Can be used for fitting both dynamic network actor models ('DyNAMs') and relational event models ('REMs'). Stadtfeld, Hollway, and Block (2017a) <doi:10.1177/0081175017709295>, Stadtfeld, Hollway, and Block (2017b) <doi:10.1177/0081175017733457>, Stadtfeld and Block (2017) <doi:10.15195/v4.a14>, Hoffman et al. (2020) <doi:10.1017/nws.2020.3>.

Data sets from the book Generalized Linear Models with Examples in R by Dunn and Smyth.

The genetic algorithm can be used directly to find the similarity of users and more effectively to increase the efficiency of the collaborative filtering method. By identifying the nearest neighbors to the active user, before the genetic algorithm, and by identifying suitable starting points, an effective method for user-based collaborative filtering method has been developed. This package uses an optimization algorithm (continuous genetic algorithm) to directly find the optimal similarities between active users (users for whom current recommendations are made) and others. First, by determining the nearest neighbor and their number, the number of genes in a chromosome is determined. Each gene represents the neighbor's similarity to the active user. By estimating the starting points of the genetic algorithm, it quickly converges to the optimal solutions. The positive point is the independence of the genetic algorithm on the number of data that for big data is an effective help in solving the problem.

This package provides probability functions (cumulative distribution and density functions), simulation function (Gumbel copula multivariate simulation) and estimation functions (Maximum Likelihood Estimation, Inference For Margins, Moment Based Estimation and Canonical Maximum Likelihood).

This package provides an R interface to the GeoNetwork API (<https://geonetwork-opensource.org/#api>) allowing to upload and publish metadata in a GeoNetwork web-application and expose it to OGC CSW.

The social network literature features numerous methods for assigning value to paths as a function of their ties. gretel systemizes these approaches, casting them as instances of a generalized path value function indexed by a penalty parameter. The package also calculates probabilistic path value and identifies optimal paths in either value framework. Finally, proximity matrices can be generated in these frameworks that capture high-order connections overlooked in primitive adjacency sociomatrices. Novel methods are described in Buch (2019) <https://davidbuch.github.io/analyzing-networks-with-gretel.html>. More traditional methods are also implemented, as described in Yang, Knoke (2001) <doi:10.1016/S0378-8733(01)00043-0>.

Make R scripts reproducible, by ensuring that every time a given script is run, the same version of the used packages are loaded (instead of whichever version the user running the script happens to have installed). This is achieved by using the command groundhog.library() instead of the base command library(), and including a date in the call. The date is used to call on the same version of the package every time (the most recent version available at that date). Load packages from CRAN, GitHub, or Gitlab.

An interactive mapping tool for geographically weighted correlation and partial correlation. Geographically weighted partial correlation coefficients are calculated following (Percival and Tsutsumida, 2017)<doi:10.1553/giscience2017_01_s36> and are described in greater detail in (Tsutsumida et al., 2019)<doi:10.5194/ica-abs-1-372-2019> and (Percival et al., 2021)<arXiv:2101.03491>.

This package provides functions to calculate the best linear unbiased prediction of genotype-by-environment metrics: ecovalence, environmental variance, Finlay and Wilkinson regression and Lin and Binns superiority measure, based on a multi-environment genomic prediction model.

Create a user-friendly plotting GUI for R'. In addition, one purpose of creating the R package is to facilitate third-party software to call R for drawing, for example, Phoenix WinNonlin software calls R to draw the drug concentration versus time curve.

The accurate annotation of genes and Quantitative Trait Loci (QTLs) located within candidate markers and/or regions (haplotypes, windows, CNVs, etc) is a crucial step the most common genomic analyses performed in livestock, such as Genome-Wide Association Studies or transcriptomics. The Genomic Annotation in Livestock for positional candidate LOci (GALLO) is an R package designed to provide an intuitive and straightforward environment to annotate positional candidate genes and QTLs from high-throughput genetic studies in livestock. Moreover, GALLO allows the graphical visualization of gene and QTL annotation results, data comparison among different grouping factors (e.g., methods, breeds, tissues, statistical models, studies, etc.), and QTL enrichment in different livestock species including cattle, pigs, sheep, and chicken, among others.

Set of functions for step-wise generation of (weighted) graphs. Aimed for research in the field of single- and multi-objective combinatorial optimization. Graphs are generated adding nodes, edges and weights. Each step may be repeated multiple times with different predefined and custom generators resulting in high flexibility regarding the graph topology and structure of edge weights.

Extension of ggplot2 providing layers, scales and preprocessing functions useful to represent behavioural variables that are recorded over multiple animals and days. This package is part of the rethomics framework <https://rethomics.github.io/>.

Modern Parallel Coordinate Plots have been introduced in the 1980s as a way to visualize arbitrarily many numeric variables. This Grammar of Graphics implementation also incorporates categorical variables into the plots in a principled manner. By separating the data managing part from the visual rendering, we give full access to the users while keeping the number of parameters manageably low.

This package provides tools for working with polygons with holes in ggplot2', with a new geom for drawing a polypath applying the evenodd or winding rules.

Inference, goodness-of-fit test, and prediction densities and intervals for univariate Gaussian Hidden Markov Models (HMM). The goodness-of-fit is based on a Cramer-von Mises statistic and uses parametric bootstrap to estimate the p-value. The description of the methodology is taken from Chapter 10.2 of Remillard (2013) <doi:10.1201/b14285>.

This package provides flexible tools for the visualization of genomic data. Supports interactive and static plots tailored for presentations and publications, with customizable features like colors, themes, and annotations to align with specific analytical and presentation goals.

This package implements the GALAHAD algorithm (Geometry-Adaptive Lyapunov-Assured Hybrid Optimizer), updated in version 2 to replace the hard-clamp positivity constraint of v1 with a numerically smooth softplus reparameterization, add rho-based trust-region adaptation (actual vs. predicted objective reduction), extend convergence detection to include both absolute and relative function-stall criteria, and enrich the per-iteration history with Armijo backtrack counts and trust-region quality ratios. Parameters constrained to be positive (rates, concentrations, scale parameters) are handled in a transformed z-space via the softplus map so that gradients remain well-defined at the constraint boundary. A two-partition API (positive / euclidean) replaces the three-way T/P/E partition of v1; the legacy form is still accepted for backwards compatibility. Designed for biological modeling problems (germination, dose-response, prion RT-QuIC, survival) where rates, concentrations, and unconstrained coefficients coexist. Developed at the Minnesota Center for Prion Research and Outreach (MNPRO), University of Minnesota. Based on Conn et al. (2000) <doi:10.1137/1.9780898719857>, Barzilai and Borwein (1988) <doi:10.1093/imanum/8.1.141>, Xu and An (2024) <doi:10.48550/arXiv.2409.14383>, Polyak (1969) <doi:10.1016/0041-5553(69)90035-4>, Nocedal and Wright (2006, ISBN:978-0-387-30303-1), and Dugas et al. (2009) <https://www.jmlr.org/papers/v10/dugas09a.html>.

Methodology that combines feature selection, model tuning, and parsimonious model selection with Genetic Algorithms (GA) proposed in Martinez-de-Pison (2015) <DOI:10.1016/j.asoc.2015.06.012>. To this objective, a novel GA selection procedure is introduced based on separate cost and complexity evaluations.

When you prepare a presentation or a report, you often need to manage a large number of ggplot figures. You need to change the figure size, modify the title, label, themes, etc. It is inconvenient to go back to the original code to make these changes. This package provides a simple way to manage ggplot figures. You can easily add the figure to the database and update them later using CLI (command line interface) or GUI (graphical user interface).

Google offers public access to global search volumes from its search engine through the Google Trends portal. The package downloads these search volumes provided by Google Trends and uses them to measure and analyze the distribution of search scores across countries or within countries. The package allows researchers and analysts to use these search scores to investigate global trends based on patterns within these scores. This offers insights such as degree of internationalization of firms and organizations or dissemination of political, social, or technological trends across the globe or within single countries. An outline of the package's methodological foundations and potential applications is available as a working paper: <https://papers.ssrn.com/sol3/papers.cfm?abstract_id=3969013>.

Real-time quantitative polymerase chain reaction (qPCR) data by Guescini et al. (2008) <doi:10.1186/1471-2105-9-326> in tidy format. This package provides two data sets where the amplification efficiency has been modulated: either by changing the amplification mix concentration, or by increasing the concentration of IgG, a PCR inhibitor. Original raw data files: <https://static-content.springer.com/esm/art%3A10.1186%2F1471-2105-9-326/MediaObjects/12859_2008_2311_MOESM1_ESM.xls> and <https://static-content.springer.com/esm/art%3A10.1186%2F1471-2105-9-326/MediaObjects/12859_2008_2311_MOESM5_ESM.xls>.

This package provides systematic, dependency-aware exploration of group sequential designs created with gsDesign'. Supports reproducible grid and random search over user-defined candidate sets, parallel evaluation via the future framework, standardized metric extraction, and auditable reporting for design-space evaluation and trade-off analysis. Methods for group sequential design are described in Anderson (2025) <doi:10.32614/CRAN.package.gsDesign>. The future framework for parallel processing is described in Bengtsson (2021) <doi:10.32614/RJ-2021-048>.