This package performs clustering of quantitative variables, assuming that clusters lie in low-dimensional subspaces. Segmentation of variables, number of clusters and their dimensions are selected based on BIC. Candidate models are identified based on many runs of K-means algorithm with different random initializations of cluster centers.

This package provides a variety of tools to allow the quantification of videos of the lymphatic vasculature taken under an operating microscope. Lymphatic vessels that have been injected with a variety of blue dyes can be tracked throughout the video to determine their width over time. Code is optimised for efficient processing of multiple large video files. Functions to calculate physiologically relevant parameters and generate graphs from these values are also included.

Facilities for constructing variance dispersion graphs, fraction- of-design-space plots and similar graphics for exploring the properties of experimental designs. The design region is explored via random sampling, which allows for more flexibility than traditional variance dispersion graphs. A formula interface is leveraged to provide access to complex model formulae. Graphics can be constructed simultaneously for multiple experimental designs and/or multiple model formulae. Instead of using pointwise optimization to find the minimum and maximum scaled prediction variance curves, which can be inaccurate and time consuming, this package uses quantile regression as an alternative.

RcppArmadillo implementation for the Matlab code of the Variational Mode Decomposition and Two-Dimensional Variational Mode Decomposition'. For more information, see (i) Variational Mode Decomposition by K. Dragomiretskiy and D. Zosso in IEEE Transactions on Signal Processing, vol. 62, no. 3, pp. 531-544, Feb.1, 2014, <doi:10.1109/TSP.2013.2288675>; (ii) Two-Dimensional Variational Mode Decomposition by Dragomiretskiy, K., Zosso, D. (2015), In: Tai, XC., Bae, E., Chan, T.F., Lysaker, M. (eds) Energy Minimization Methods in Computer Vision and Pattern Recognition. EMMCVPR 2015. Lecture Notes in Computer Science, vol 8932. Springer, <doi:10.1007/978-3-319-14612-6_15>.

An implementation of the Likelihood ratio Test (LRT) for testing that, in a (non)linear mixed effects model, the variances of a subset of the random effects are equal to zero. There is no restriction on the subset of variances that can be tested: for example, it is possible to test that all the variances are equal to zero. Note that the implemented test is asymptotic. This package should be used on model fits from packages nlme', lmer', and saemix'. Charlotte Baey and Estelle Kuhn (2019) <doi:10.18637/jss.v107.i06>.

This package provides functions for estimation (parametric, semi-parametric and non-parametric) of copula-based dependence coefficients between a finite collection of random vectors, including phi-dependence measures and Bures-Wasserstein dependence measures. An algorithm for agglomerative hierarchical variable clustering is also implemented. Following the articles De Keyser & Gijbels (2024) <doi:10.1016/j.jmva.2024.105336>, De Keyser & Gijbels (2024) <doi:10.1016/j.ijar.2023.109090>, and De Keyser & Gijbels (2024) <doi:10.48550/arXiv.2404.07141>.

This package provides helper functions and wrappers to simplify authentication, data retrieval, and result processing from the VALD APIs'. Designed to streamline integration for analysts and researchers working with VALD's external APIs'. For further documentation on integrating with VALD APIs', see: <https://support.vald.com/hc/en-au/articles/23415335574553-How-to-integrate-with-VALD-APIs>. For a step-by-step guide to using this package, see: <https://support.vald.com/hc/en-au/articles/48730811824281-A-guide-to-using-the-valdr-R-package>.

This package provides templates and functions to simplify the production and maintenance of curriculum vitae.

Graphs the pdf or pmf and highlights what area or probability is present in user defined locations. Visualize is able to provide lower tail, bounded, upper tail, and two tail calculations. Supports strict and equal to inequalities. Also provided on the graph is the mean and variance of the distribution.

This package implements a set of routines to perform structured matrix factorization with minimum volume constraints. The NMF procedure decomposes a matrix X into a product C * D. Given conditions such that the matrix C is non-negative and has sufficiently spread columns, then volume minimization of a matrix D delivers a correct and unique, up to a scale and permutation, solution (C, D). This package provides both an implementation of volume-regularized NMF and "anchor-free" NMF, whereby the standard NMF problem is reformulated in the covariance domain. This algorithm was applied in Vladimir B. Seplyarskiy Ruslan A. Soldatov, et al. "Population sequencing data reveal a compendium of mutational processes in the human germ line". Science, 12 Aug 2021. <doi:10.1126/science.aba7408>. This package interacts with data available through the simulatedNMF package, which is available in a drat repository. To access this data package, see the instructions at <https://github.com/kharchenkolab/vrnmf>. The size of the simulatedNMF package is approximately 8 MB.

This package provides users with a simple and convenient mechanism to manage and query a Virtuoso database using the DBI (Data-Base Interface) compatible ODBC (Open Database Connectivity) interface. Virtuoso is a high-performance "universal server," which can act as both a relational database, supporting standard Structured Query Language ('SQL') queries, while also supporting data following the Resource Description Framework ('RDF') model for Linked Data. RDF data can be queried using SPARQL ('SPARQL Protocol and RDF Query Language) queries, a graph-based query that supports semantic reasoning. This allows users to leverage the performance of local or remote Virtuoso servers using popular R packages such as DBI and dplyr', while also providing a high-performance solution for working with large RDF triplestores from R. The package also provides helper routines to install, launch, and manage a Virtuoso server locally on Mac', Windows and Linux platforms using the standard interactive installers from the R command-line. By automatically handling these setup steps, the package can make using Virtuoso considerably faster and easier for a most users to deploy in a local environment. Managing the bulk import of triples from common serializations with a single intuitive command is another key feature of this package. Bulk import performance can be tens to hundreds of times faster than the comparable imports using existing R tools, including rdflib and redland packages.

This package provides a collection of statistical tests for martingale difference hypothesis, including automatic portmanteau test (Escansiano and Lobato, 2009) <doi:10.1016/j.jeconom.2009.03.001> and automatic variance ratio test (Kim, 2009) <doi:10.1016/j.frl.2009.04.003>.

Analyze Peptide Array Data and characterize peptide sequence space. Allows for high level visualization of global signal, Quality control based on replicate correlation and/or relative Kd, calculation of peptide Length/Charge/Kd parameters, Hits selection based on RFU Signal, and amino acid composition/basic motif recognition with RFU signal weighting. Basic signal trends can be used to generate peptides that follow the observed compositional trends.

Conversion of characters from unsupported Vietnamese character encodings to Unicode characters. These Vietnamese encodings (TCVN3, VISCII, VPS) are not natively supported in R and lead to printing of wrong characters and garbled text (mojibake). This package fixes that problem and provides readable output with the correct Unicode characters (with or without diacritics).

This package produces violin plots with optional nonparametric (Mann-Whitney test) and parametric (Tukey's honest significant difference) mean comparison and linear regression. This package aims to be a simple and quick visualization tool for comparing means and assessing trends of categorical factors.

The base class VirtualArray is defined, which acts as a wrapper around lists allowing users to fold arbitrary sequential data into n-dimensional, R-style virtual arrays. The derived XArray class is defined to be used for homogeneous lists that contain a single class of objects. The RasterArray and SfArray classes enable the use of stacked spatial data instead of lists.

This package provides methods for faster extraction (about 5x faster in a few test cases) of variance-covariance matrices and standard errors from models. Methods in the stats package tend to rely on the summary method, which may waste time computing other summary statistics which are summarily ignored.

This package provides an htmlwidgets interface to VChart.js'. VChart', more than just a cross-platform charting library, but also an expressive data storyteller. VChart examples and documentation are available here: <https://www.visactor.io/vchart>.

This package provides a dedicated viral-explainer model tool designed to empower researchers in the field of HIV research, particularly in viral load and CD4 (Cluster of Differentiation 4) lymphocytes regression modeling. Drawing inspiration from the tidymodels framework for rigorous model building of Max Kuhn and Hadley Wickham (2020) <https://www.tidymodels.org>, and the DALEXtra tool for explainability by Przemyslaw Biecek (2020) <doi:10.48550/arXiv.2009.13248>. It aims to facilitate interpretable and reproducible research in biostatistics and computational biology for the benefit of understanding HIV dynamics.

Declare data validation rules and data quality indicators; confront data with them and analyze or visualize the results. The package supports rules that are per-field, in-record, cross-record or cross-dataset. Rules can be automatically analyzed for rule type and connectivity. Supports checks implied by an SDMX DSD file as well. See also Van der Loo and De Jonge (2018) <doi:10.1002/9781118897126>, Chapter 6 and the JSS paper (2021) <doi:10.18637/jss.v097.i10>.

Various semiparametric and nonparametric statistical tools for immune correlates analysis of vaccine clinical trial data. This includes calculation of summary statistics and estimation of risk, vaccine efficacy, controlled effects (controlled risk and controlled vaccine efficacy), and mediation effects (natural direct effect, natural indirect effect, proportion mediated). See Gilbert P, Fong Y, Kenny A, and Carone, M (2022) <doi:10.1093/biostatistics/kxac024> and Fay MP and Follmann DA (2023) <doi:10.48550/arXiv.2208.06465>.

This package provides a toolset for interactively exploring the differences between two data frames.

The variable importance is calculated using knock off variables. Then output can be provided in numerical and graphical form. Meredith L Wallace (2023) <doi:10.1186/s12874-023-01965-x>.

Variance function estimation for models proposed by W. Sadler in his variance function program ('VFP', www.aacb.asn.au/AACB/Resources/Variance-Function-Program). Here, the idea is to fit multiple variance functions to a data set and consequently assess which function reflects the relationship Var ~ Mean best. For in-vitro diagnostic ('IVD') assays modeling this relationship is of great importance when individual test-results are used for defining follow-up treatment of patients.