Biclustering, row clustering and column clustering using the proportional odds model (POM), ordered stereotype model (OSM) or binary model for ordinal categorical data. Fernández, D., Arnold, R., Pledger, S., Liu, I., & Costilla, R. (2019) <doi:10.1007/s11634-018-0324-3>.

The design of this package allows us to run different clustering packages and compare the results between them, to determine which algorithm behaves best from the data provided. See Martos, L.A.P., Garcà a-Vico, à .M., González, P. et al.(2023) <doi:10.1007/s13748-022-00294-2> "Clustering: an R library to facilitate the analysis and comparison of cluster algorithms.", Martos, L.A.P., Garcà a-Vico, à .M., González, P. et al. "A Multiclustering Evolutionary Hyperrectangle-Based Algorithm" <doi:10.1007/s44196-023-00341-3> and L.A.P., Garcà a-Vico, à .M., González, P. et al. "An Evolutionary Fuzzy System for Multiclustering in Data Streaming" <doi:10.1016/j.procs.2023.12.058>.

Predicts anticancer peptides using random forests trained on the n-gram encoded peptides. The implemented algorithm can be accessed from both the command line and shiny-based GUI. The CancerGram model is too large for CRAN and it has to be downloaded separately from the repository: <https://github.com/BioGenies/CancerGramModel>. For more information see: Burdukiewicz et al. (2020) <doi:10.3390/pharmaceutics12111045>.

This package provides a one-stop shop for intuitive and dependency-free color and palette creation and modification. Includes palettes and functionality from popular packages such as viridis', RColorBrewer', and base R grDevices', as well as ggplot2 plot bindings. Users can generate perceptually uniform and colorblind-friendly palettes, adjust palettes in HSL and RGB color spaces, map color gradients to value ranges, and create color-generating functions.

Fits constrained groupwise additive index models and provides functions for inference and interpretation of these models. The method is described in Masselot, Chebana, Campagna, Lavigne, Ouarda, Gosselin (2022) "Constrained groupwise additive index models" <doi:10.1093/biostatistics/kxac023>.

Make fake data that looks realistic, supporting addresses, person names, dates, times, colors, coordinates, currencies, digital object identifiers ('DOIs'), jobs, phone numbers, DNA sequences, doubles and integers from distributions and within a range.

An R implementation of the Critical Path Method (CPM). CPM is a method used to estimate the minimum project duration and determine the amount of scheduling flexibility on the logical network paths within the schedule model. The flexibility is in terms of early start, early finish, late start, late finish, total float and free float. Beside, it permits to quantify the complexity of network diagram through the analysis of topological indicators. Finally, it permits to change the activities duration to perform what-if scenario analysis. The package was built based on following references: To make topological sorting and other graph operation, we use Csardi, G. & Nepusz, T. (2005) <https://www.researchgate.net/publication/221995787_The_Igraph_Software_Package_for_Complex_Network_Research>; For schedule concept, the reference was Project Management Institute (2017) <https://www.pmi.org/pmbok-guide-standards/foundational/pmbok>; For standards terms, we use Project Management Institute (2017) <https://www.pmi.org/pmbok-guide-standards/lexicon>; For algorithms on Critical Path Method development, we use Vanhoucke, M. (2013) <doi:10.1007/978-3-642-40438-2> and Vanhoucke, M. (2014) <doi:10.1007/978-3-319-04331-9>; And, finally, for topological definitions, we use Vanhoucke, M. (2009) <doi:10.1007/978-1-4419-1014-1>.

This package contains the R functions needed to perform Cluster-Of-Clusters Analysis (COCA) and Consensus Clustering (CC). For further details please see Cabassi and Kirk (2020) <doi:10.1093/bioinformatics/btaa593>.

Gives convenient access to publicly available police-recorded open crime data from large cities in the United States that are included in the Crime Open Database <https://osf.io/zyaqn/>.

This package provides functions for predictor pruning using association-based and model-based approaches. Includes corrPrune() for fast correlation-based pruning, modelPrune() for VIF-based regression pruning, and exact graph-theoretic algorithms (Eppsteinâ Löfflerâ Strash, Bronâ Kerbosch) for exhaustive subset enumeration. Supports linear models, GLMs, and mixed models ('lme4', glmmTMB').

Perform likelihood estimation and corresponding analysis under the copula-based Markov chain model for serially dependent event times with a dependent terminal event. Available are statistical methods in Huang, Wang and Emura (2020, JJSD accepted).

This package performs survival analysis using general non-linear models. Risk models can be the sum or product of terms. Each term is the product of exponential/linear functions of covariates. Additionally sub-terms can be defined as a sum of exponential, linear threshold, and step functions. Cox Proportional hazards <https://en.wikipedia.org/wiki/Proportional_hazards_model>, Poisson <https://en.wikipedia.org/wiki/Poisson_regression>, and Fine-Gray competing risks <https://www.publichealth.columbia.edu/research/population-health-methods/competing-risk-analysis> regression are supported. This work was sponsored by NASA Grants 80NSSC19M0161 and 80NSSC23M0129 through a subcontract from the National Council on Radiation Protection and Measurements (NCRP). The computing for this project was performed on the Beocat Research Cluster at Kansas State University, which is funded in part by NSF grants CNS-1006860, EPS-1006860, EPS-0919443, ACI-1440548, CHE-1726332, and NIH P20GM113109.

Includes several classifications such as International Statistical Classification of Diseases and Related Health Problems 10th Revision (ICD10), Anatomical Therapeutic Chemical (ATC) Classification, The International Classification of Diseases for Oncology (ICD-O-3), and International Classification of Primary Care (ICPC). Includes function that adds descriptive label to code value. Depending on classification following languages are available: English, Finnish, Swedish, and Latin.

Copula-based imputation methods: parametric and nonparametric algorithms for missing multivariate data through conditional copulas.

Chemical analysis of proteins based on their amino acid compositions. Amino acid compositions can be read from FASTA files and used to calculate chemical metrics including carbon oxidation state and stoichiometric hydration state, as described in Dick et al. (2020) <doi:10.5194/bg-17-6145-2020>. Other properties that can be calculated include protein length, grand average of hydropathy (GRAVY), isoelectric point (pI), molecular weight (MW), standard molal volume (V0), and metabolic costs (Akashi and Gojobori, 2002 <doi:10.1073/pnas.062526999>; Wagner, 2005 <doi:10.1093/molbev/msi126>; Zhang et al., 2018 <doi:10.1038/s41467-018-06461-1>). A database of amino acid compositions of human proteins derived from UniProt is provided.

This package provides a first-principle, phylogeny-aware comparative genomics tool for investigating associations between terms used to annotate genomic components (e.g., Pfam IDs, Gene Ontology terms,) with quantitative or rank variables such as number of cell types, genome size, or density of specific genomic elements. See the project website for more information, documentation and examples, and <doi:10.1016/j.patter.2023.100728> for the full paper.

An R client for the currencyapi.com currency conversion API. The API requires registration of an API key. Basic features are free, some require a paid subscription. You can find the full API documentation at <https://currencyapi.com/docs> .

This package contains some commonly used categorical variable encoders, such as LabelEncoder and OneHotEncoder'. Inspired by the encoders implemented in Python sklearn.preprocessing package (see <http://scikit-learn.org/stable/modules/preprocessing.html>).

Immune related gene sets provided along with the cinaR package.

We present corto (Correlation Tool), a simple package to infer gene regulatory networks and visualize master regulators from gene expression data using DPI (Data Processing Inequality) and bootstrapping to recover edges. An initial step is performed to calculate all significant edges between a list of source nodes (centroids) and target genes. Then all triplets containing two centroids and one target are tested in a DPI step which removes edges. A bootstrapping process then calculates the robustness of the network, eventually re-adding edges previously removed by DPI. The algorithm has been optimized to run outside a computing cluster, using a fast correlation implementation. The package finally provides functions to calculate network enrichment analysis from RNA-Seq and ATAC-Seq signatures as described in the article by Giorgi lab (2020) <doi:10.1093/bioinformatics/btaa223>.

This package provides access to the Calcite Design System javascript components via integration with the htmltools and shiny packages. Pre-built and interactive components can be used to generate either static html or interactive web applications. Learn more about the Calcite Design System at <https://developers.arcgis.com/calcite-design-system/>.

Maps one of the viridis colour palettes, or a user-specified palette to values. Viridis colour maps are created by Stéfan van der Walt and Nathaniel Smith, and were set as the default palette for the Python Matplotlib library <https://matplotlib.org/>. Other palettes available in this library have been derived from RColorBrewer <https://CRAN.R-project.org/package=RColorBrewer> and colorspace <https://CRAN.R-project.org/package=colorspace> packages.

Fits predictive and symmetric co-correspondence analysis (CoCA) models to relate one data matrix to another data matrix. More specifically, CoCA maximises the weighted covariance between the weighted averaged species scores of one community and the weighted averaged species scores of another community. CoCA attempts to find patterns that are common to both communities.

Produce forest plots to visualize covariate effects using either the command line or an interactive Shiny application.