Calculates the cost of crossing in terms of the number of individuals and generations, which is theoretically formulated by Servin et al. (2004) <DOI:10.1534/genetics.103.023358>. This package has been designed for selecting appropriate parental genotypes and find the most efficient crossing scheme for gene pyramiding, especially for plant breeding.

This package provides a comprehensive interface for Google Gemini API, enabling users to access and utilize Gemini Large Language Model (LLM) functionalities directly from R. This package facilitates seamless integration with Google Gemini, allowing for advanced language processing, text generation, and other AI-driven capabilities within the R environment. For more information, please visit <https://ai.google.dev/docs/gemini_api_overview>.

This package provides a series of functions to generate a pedigree around a given person with a known genetic mutation, based on US census data. Pedigree will also track mutation status of all members. Pedigree is built down to children, back to grandparents, and out to cousins. There is also a function to generate pedigrees without genetic mutations.

This package implements a generalized coordinate descent (GCD) algorithm for computing the solution paths of the hybrid Huberized support vector machine (HHSVM) and its generalizations. Supported models include the (adaptive) LASSO and elastic net penalized least squares, logistic regression, HHSVM, squared hinge loss SVM and expectile regression.

Allows plotting data on bathymetric maps using ggplot2'. Plotting oceanographic spatial data is made as simple as feasible, but also flexible for custom modifications. Data that contain geographic information from anywhere around the globe can be plotted on maps generated by the basemap() or qmap() functions using ggplot2 layers separated by the + operator. The package uses spatial shape- ('sf') and raster ('stars') files, geospatial packages for R to manipulate, and the ggplot2 package to plot these files. The package ships with low-resolution spatial data files and higher resolution files for detailed maps are stored in the ggOceanMapsLargeData repository on GitHub and downloaded automatically when needed.

This package implements the gene-based segregation test(GESE) and the weighted GESE test for identifying genes with causal variants of large effects for family-based sequencing data. The methods are described in Qiao, D. Lange, C., Laird, N.M., Won, S., Hersh, C.P., et al. (2017). <DOI:10.1002/gepi.22037>. Gene-based segregation method for identifying rare variants for family-based sequencing studies. Genet Epidemiol 41(4):309-319. More details can be found at <http://scholar.harvard.edu/dqiao/gese>.

Generates a file, containing the main scientific references, prepared to be automatically inserted into an academic paper. The articles present in the list are chosen from the main references generated, by function principal_lister(), of the package bibliorefer'. The generated file contains the list of metadata of the principal references in BibTex format. Massimo Aria, Corrado Cuccurullo. (2017) <doi:10.1016/j.joi.2017.08.007>. Caibo Zhou, Wenyan Song. (2021) <doi:10.1016/j.jclepro.2021.126943>. Hamid DerviÅ . (2019) <doi:10.5530/jscires.8.3.32>.

This package provides tools to interact nicely with the Genius API <https://docs.genius.com/>. Search hosted content, extract associated metadata and retrieve lyrics with ease.

Fits high dimensional penalized generalized linear mixed models using the Monte Carlo Expectation Conditional Minimization (MCECM) algorithm. The purpose of the package is to perform variable selection on both the fixed and random effects simultaneously for generalized linear mixed models. The package supports fitting of Binomial, Gaussian, and Poisson data with canonical links, and supports penalization using the MCP, SCAD, or LASSO penalties. The MCECM algorithm is described in Rashid et al. (2020) <doi:10.1080/01621459.2019.1671197>. The techniques used in the minimization portion of the procedure (the M-step) are derived from the procedures of the ncvreg package (Breheny and Huang (2011) <doi:10.1214/10-AOAS388>) and grpreg package (Breheny and Huang (2015) <doi:10.1007/s11222-013-9424-2>), with appropriate modifications to account for the estimation and penalization of the random effects. The ncvreg and grpreg packages also describe the MCP, SCAD, and LASSO penalties.

This package provides functions for drawing scene trees representing scenes that have been drawn using grid graphics.

This package provides a statistical hypothesis test for conditional independence. Given residuals from a sufficiently powerful regression, it tests whether the covariance of the residuals is vanishing. It can be applied to both discretely-observed functional data and multivariate data. Details of the method can be found in Anton Rask Lundborg, Rajen D. Shah and Jonas Peters (2022) <doi:10.1111/rssb.12544>.

Features the marginal parametric and semi-parametric proportional hazards mixture cure models for analyzing clustered survival data with a possible cure fraction. A reference is Yi Niu and Yingwei Peng (2014) <doi:10.1016/j.jmva.2013.09.003>.

This package provides a bottom up model to estimate the emission levels of public transport systems based on General Transit Feed Specification (GTFS) data. The package requires two main inputs: i) Public transport data in the GTFS standard format; and ii) Some basic information on fleet characteristics such as fleet age, technology, fuel and Euro stage. As it stands, the package estimates several pollutants at high spatial and temporal resolutions. Pollution levels can be calculated for specific transport routes, trips, time of the day or for the transport system as a whole. The output with emission estimates can be extracted in different formats, supporting analysis on how emission levels vary across space, time and by fleet characteristics. A full description of the methods used in the gtfs2emis model is presented in Vieira, J. P. B.; Pereira, R. H. M.; Andrade, P. R. (2022) <doi:10.31219/osf.io/8m2cy>.

Genotyping of triploid individuals from luminescence data (marker probeset A and B). Works also for diploids. Two main functions: Run_Clustering() that regroups individuals with a same genotype based on proximity and Run_Genotyping() that assigns a genotype to each cluster. For Shiny interface use: launch_GenoShiny().

This package provides a multi-platform user interface for drawing highly customizable graphs in R. It aims to be a valuable help to quickly draw publishable graphs without any knowledge of R commands. Six kinds of graph are available: histogram, box-and-whisker plot, bar plot, pie chart, curve and scatter plot.

This package provides basic graphing functions to fully demonstrate point-to-point connections in a polar coordinate space.

Given a landscape resistance surface, creates minimum planar graph (Fall et al. (2007) <doi:10.1007/s10021-007-9038-7>) and grains of connectivity (Galpern et al. (2012) <doi:10.1111/j.1365-294X.2012.05677.x>) models that can be used to calculate effective distances for landscape connectivity at multiple scales. Documentation is provided by several vignettes, and a paper (Chubaty, Galpern & Doctolero (2020) <doi:10.1111/2041-210X.13350>).

Create and maintain delayed-data packages (ddp's). Data stored in a ddp are available on demand, but do not take up memory until requested. You attach a ddp with g.data.attach(), then read from it and assign to it in a manner similar to S-PLUS, except that you must run g.data.save() to actually commit to disk.

The function gggap() streamlines the creation of segments on the y-axis of ggplot2 plots which is otherwise not a trivial task to accomplish.

Sequential change-point tests, parameters estimation, and goodness-of-fit tests for generalized Ornstein-Uhlenbeck processes.

Promote access to the GESLA <https://gesla787883612.wordpress.com> (Global Extreme Sea Level Analysis) dataset, a higher-frequency sea-level record data from all over the world. It provides functions to download it entirely, or query subsets directly into R, without the need of downloading the full dataset. Also, it provides a built-in web-application, so that users can apply basic filters to select the data of interest, generating informative plots, and showing the selected sites.

Design and analysis of group sequential designs for negative binomial outcomes, as described by T Mütze, E Glimm, H Schmidli, T Friede (2018) <doi:10.1177/0962280218773115>.

Quantitative genetics tool supporting the modelling of multivariate genetic variance structures in quantitative data. It allows fitting different models through multivariate genetic-relationship-matrix (GRM) structural equation modelling (SEM) in unrelated individuals, using a maximum likelihood approach. Specifically, it combines genome-wide genotyping information, as captured by GRMs, with twin-research-based SEM techniques, St Pourcain et al. (2017) <doi:10.1016/j.biopsych.2017.09.020>, Shapland et al. (2020) <doi:10.1101/2020.08.14.251199>.

Parameter estimation and prediction of Gaussian Process Classifier models as described in Bachoc et al. (2020) <doi:10.1007/S10898-020-00920-0>. Important functions : gpcm(), predict.gpcm(), update.gpcm().