Quantitative trait loci mapping and genome wide association analysis are used to find candidate molecular marker or region associated with phenotype based on linkage analysis and linkage disequilibrium. Gene expression quantitative trait loci mapping is used to find candidate molecular marker or region associated with gene expression. In this package, we applied the method in Liu W. (2011) <doi:10.1007/s00122-011-1631-7> and Gusev A. (2016) <doi:10.1038/ng.3506> to genome and transcriptome wide association study, which is aimed at revealing the association relationship between phenotype and molecular markers, expression levels, molecular markers nested within different related expression effect and expression effect nested within different related molecular marker effect. F test based on full and reduced model are performed to obtain p value or likelihood ratio statistic. The best linear model can be obtained by stepwise regression analysis.

This package provides functions and necessary JavaScript bindings to quickly transfer spatial data from R memory or remote URLs to the browser for use in interactive HTML widgets created with the htmlwidgets R package. Leverages GeoArrow (<https://geoarrow.org/>) data representation for data stored in local R memory which is generally faster than traditional GeoJSON by minimising the amount of copy, serialization and deserialization steps necessary for the data transfer. Furthermore, provides functionality and JavaScript bindings to consume GeoParquet (<https://geoparquet.org/>) files from remote URLs in the browser.

Density function and generation of random variables from the Generalized Inverse Normal (GIN) distribution from Robert (1991) <doi:10.1016/0167-7152(91)90174-P>. Also provides density functions and generation from the GIN distribution truncated to positive or negative reals. Theoretical guarantees supporting the sampling algorithms and an application to Bayesian estimation of network formation models can be found in the working paper Ding, Estrada and Montoya-Blandón (2023) <https://www.smontoyablandon.com/publication/networks/network_externalities.pdf>.

This package performs Gamma regression, where both mean and shape parameters follows lineal regression structures.

This package provides functions to produce ggplot2'-based plots of objects produced by functions in the vegan package. Provides fortify()', autoplot()', and tidy() methods for many of vegan''s functions. The aim of ggvegan is to make it easier to work within the tidyverse with vegan'.

This package purposes to deal with public survey data of Japanese government via their Application Programming Interface (http://statdb.nstac.go.jp/).

R-interface to C++ implementation of the rank/score permutation based GSEA test (Subramanian et al 2005 <doi: 10.1073/pnas.0506580102>).

Gene and Region Counting of Mutations (GARCOM) package computes mutation (or alleles) counts per gene per individuals based on gene annotation or genomic base pair boundaries. It comes with features to accept data formats in plink(.raw) and VCF. It provides users flexibility to extract and filter individuals, mutations and genes of interest.

Hierarchical Bayesian models. The package provides tools to fit two response time models, using the population-based Markov Chain Monte Carlo.

This package provides a workflow for correction of Differential Interferometric Synthetic Aperture Radar (DInSAR) atmospheric delay base on Generic Atmospheric Correction Online Service for InSAR (GACOS) data and correction algorithms proposed by Chen Yu. This package calculate the Both Zenith and LOS direction (User Depend). You have to just download GACOS product on your area and preprocessed D-InSAR unwrapped images. Cite those references and this package in your work, when using this framework. References: Yu, C., N. T. Penna, and Z. Li (2017) <doi:10.1016/j.rse.2017.10.038>. Yu, C., Li, Z., & Penna, N. T. (2017) <doi:10.1016/j.rse.2017.10.038>. Yu, C., Penna, N. T., and Li, Z. (2017) <doi:10.1002/2016JD025753>.

This package implements the generalized Gauss Markov regression, this is useful when both predictor and response have uncertainty attached to them and also when covariance within the predictor, within the response and between the predictor and the response is present. Base on the results published in guide ISO/TS 28037 (2010) <https://www.iso.org/standard/44473.html>.

This package implements methods to plot periodic data in any arbitrary range on the fly.

Estimation of generalized linear models with correlated/clustered observations by use of generalized estimating equations (GEE). See e.g. Halekoh and Højsgaard, (2005, <doi:10.18637/jss.v015.i02>), for details. Several types of clustering are supported, including exchangeable variance structures, AR1 structures, M-dependent, user-specified variance structures and more. The model fitting computations are performed using modified code from the geeM package, while the interface and output objects have been written to resemble the geepack package. The package also contains additional tools for working with and inspecting results from the geepack package, e.g. a confint method for geeglm objects from geepack'.

This package creates presentation-ready tables summarizing data sets, regression models, and more. The code to create the tables is concise and highly customizable. Data frames can be summarized with any function, e.g. mean(), median(), even user-written functions. Regression models are summarized and include the reference rows for categorical variables. Common regression models, such as logistic regression and Cox proportional hazards regression, are automatically identified and the tables are pre-filled with appropriate column headers.

Performing the different steps of gene set enrichment meta-analysis. It provides different functions that allow the application of meta-analysis based on the combination of effect sizes from different pathways in different studies to obtain significant pathways that are common to all of them.

This package implements a variant of the Self-Organizing Map (SOM) algorithm designed for mixed-attribute datasets. Similarity between observations is computed using the Gower distance, and categorical prototypes are updated via heuristic strategies (weighted mode and multinomial sampling). Provides functions for model fitting, mapping, visualization (U-Matrix and component planes), and evaluation, making SOM applicable to heterogeneous real-world data. For methodological details see Sáez and Salas (2026) <doi:10.1007/s41060-025-00941-6>.

Design of group sequential trials, including non-binding futility analysis at multiple time points (Gallo, Mao, and Shih, 2014, <doi:10.1080/10543406.2014.932285>).

The genridge package introduces generalizations of the standard univariate ridge trace plot used in ridge regression and related methods. These graphical methods show both bias (actually, shrinkage) and precision, by plotting the covariance ellipsoids of the estimated coefficients, rather than just the estimates themselves. 2D and 3D plotting methods are provided, both in the space of the predictor variables and in the transformed space of the PCA/SVD of the predictors.

Create hexagonal heatmaps with ggplot2', using the size aesthetic to variably size each hexagon.

This package provides a mechanism to plot a Google Map from R and overlay it with shapes and markers. Also provides access to Google Maps APIs, including places, directions, roads, distances, geocoding, elevation and timezone.

Provide specialized ggplot2 layers and scales for spatial uncertainty visualization, including bivariate choropleth maps, pixel maps, glyph maps, and exceedance probability maps.

Allows users to generate a gendered language score according to the gendered language dictionary in Roberts and Utych (2019) <doi:10.1177/1065912919874883>.

This package provides a ggplot2 extension that enables robust image grobs in panels and theme elements.

Computes experimental designs for two-arm experiments with covariates using multiple methods, including: (0) complete randomization and randomization with forced-balance; (1) greedy optimization of a balance objective function via pairwise switching; (2) numerical optimization via gurobi'; (3) rerandomization; (4) Karp's method for one covariate; (5) exhaustive enumeration for small sample sizes; (6) binary pair matching using nbpMatching'; (7) binary pair matching plus method (1) to further optimize balance; (8) binary pair matching plus method (3) to further optimize balance; (9) Hadamard designs; and (10) simultaneous multiple kernels. For the greedy, rerandomization, and related methods, three objective functions are supported: Mahalanobis distance, standardized sums of absolute differences, and kernel distances via the kernlab library. This package is the result of a stream of research that can be found in Krieger, A. M., Azriel, D. A., and Kapelner, A. (2019). "Nearly Random Designs with Greatly Improved Balance." Biometrika 106(3), 695-701 <doi:10.1093/biomet/asz026>. Krieger, A. M., Azriel, D. A., and Kapelner, A. (2023). "Better experimental design by hybridizing binary matching with imbalance optimization." Canadian Journal of Statistics, 51(1), 275-292 <doi:10.1002/cjs.11685>.