Computes a single scalar metric for diurnal cortisol cycle analysis, the Cortisol Sine Score (CSS). The score is calculated as the sum over time points of concentration multiplied by sin(2 * pi * time / 24), giving positive weights to morning time points and negative weights to evening ones. The method is model-free, robust, and suitable for regression, classification, clustering, and biomarker research.

Examine any number of time series data frames to identify instances in which various criteria are met within specified time frames. In clinical medicine, these types of events are often called "constellations of signs and symptoms", because a single condition depends on a series of events occurring within a certain amount of time of each other. This package was written to work with any number of time series data frames and is optimized for speed to work well with data frames with millions of rows.

Provided data containing an outcome variable, compositional variables and additional covariates (optional); linearly regress the outcome variable on an isometric log ratio (ilr) transformation of the linearly dependent compositional variables. The package provides predictions (with confidence intervals) in the change (delta) in the outcome/response variable based on the multiple linear regression model and evenly spaced reallocations of the compositional values. The compositional data analysis approach implemented is outlined in Dumuid et al. (2017a) <doi:10.1177/0962280217710835> and Dumuid et al. (2017b) <doi:10.1177/0962280217737805>.

Returns an edit-distance based clusterization of an input vector of strings. Each cluster will contain a set of strings w/ small mutual edit-distance (e.g., Levenshtein, optimum-sequence-alignment, Damerau-Levenshtein), as computed by stringdist::stringdist(). The set of all mutual edit-distances is then used by graph algorithms (from package igraph') to single out subsets of high connectivity.

This package provides text analysis in R, focusing on the use of a tokenized text format. In this format, the positions of tokens are maintained, and each token can be annotated (e.g., part-of-speech tags, dependency relations). Prominent features include advanced Lucene-like querying for specific tokens or contexts (e.g., documents, sentences), similarity statistics for words and documents, exporting to DTM for compatibility with many text analysis packages, and the possibility to reconstruct original text from tokens to facilitate interpretation.

An end-to-end framework that enables users to implement various descriptive studies for a given set of target and outcome cohorts for data mapped to the Observational Medical Outcomes Partnership Common Data Model.

Creation of interactive tables, listings and figures ('TLFs') and associated report for exploratory analysis of data in a clinical trial, e.g. for clinical oversight activities. Interactive figures include sunburst, treemap, scatterplot, line plot and barplot of counts data. Interactive tables include table of summary statistics (as counts of adverse events, enrollment table) and listings. Possibility to compare data (summary table or listing) across two data batches/sets. A clinical data review report is created via study-specific configuration files and template R Markdown reports contained in the package.

This package provides a simple interface for multivariate correlation analysis that unifies various classical statistical procedures including t-tests, tests in univariate and multivariate linear models, parametric and nonparametric tests for correlation, Kruskal-Wallis tests, common approximate versions of Wilcoxon rank-sum and signed rank tests, chi-squared tests of independence, score tests of particular hypotheses in generalized linear models, canonical correlation analysis and linear discriminant analysis.

This package produces statistical indicators of the impact of migration on the socio-demographic composition of an area. Three measures can be used: ratios, percentages and the Duncan index of dissimilarity. The input data files are assumed to be in an origin-destination matrix format, with each cell representing a flow count between an origin and a destination area. Columns are expected to represent origins, and rows are expected to represent destinations. The first row and column are assumed to contain labels for each area. See Rodriguez-Vignoli and Rowe (2018) <doi:10.1080/00324728.2017.1416155> for technical details.

Package for the analysis of categorical functional data. The main purpose is to compute an encoding (real functional variable) for each state <doi:10.3390/math9233074>. It also provides functions to perform basic statistical analysis on categorical functional data.

Estimates tree crown scorch from terrestrial lidar scans collected with a RIEGL vz400i. The methods follow those described in Cannon et al. (2025, Fire Ecology 21:71, <doi:10.1186/s42408-025-00420-0>).

Loads and displays images, selectively masks specified background colors, bins pixels by color using either data-dependent or automatically generated color bins, quantitatively measures color similarity among images using one of several distance metrics for comparing pixel color clusters, and clusters images by object color similarity. Uses CIELAB, RGB, or HSV color spaces. Originally written for use with organism coloration (reef fish color diversity, butterfly mimicry, etc), but easily applicable for any image set.

Estimation, testing and regression modeling of subdistribution functions in competing risks using quantile regressions, as described in Peng and Fine (2009) <DOI:10.1198/jasa.2009.tm08228>.

Search across R files with contextual results, highlights and clickable links. Includes an add-in for further workflow enhancement.

This package provides equations commonly used in clinical pharmacokinetics and clinical pharmacology, such as equations for dose individualization, compartmental pharmacokinetics, drug exposure, anthropomorphic calculations, clinical chemistry, and conversion of common clinical parameters. Where possible and relevant, it provides multiple published and peer-reviewed equations within the respective R function.

This package provides functions for reading in and manipulating CRU TS3.21: Climatic Research Unit (CRU) Time-Series (TS) Version 3.21 data.

Cluster analysis of a set of variables. Variables can be quantitative, qualitative or a mixture of both.

Color and visualize wildlife distributions in space-time using raster data. In addition to enabling display of sequential change in distributions through the use of small multiples, colorist provides functions for extracting several features of interest from a sequence of distributions and for visualizing those features using HCL (hue-chroma-luminance) color palettes. Resulting maps allow for "fair" visual comparison of intensity values (e.g., occurrence, abundance, or density) across space and time and can be used to address questions about where, when, and how consistently a species, group, or individual is likely to be found.

Compare two classifications or clustering solutions that may or may not have the same number of classes, and that might have hard or soft (fuzzy, probabilistic) membership. Calculate various metrics to assess how the clusters compare to each other. The calculations are simple, but provide a handy tool for users unfamiliar with matrix multiplication. This package is not geared towards traditional accuracy assessment for classification/ mapping applications - the motivating use case is for comparing a probabilistic clustering solution to a set of reference or existing class labels that could have any number of classes (that is, without having to degrade the probabilistic clustering to hard classes).

This package performs the cross-match test that is an exact, distribution free test of equality of 2 high dimensional multivariate distributions. The input is a distance matrix and the labels of the two groups to be compared, the output is the number of cross-matches and a p-value. See Rosenbaum (2005) <doi:10.1111/j.1467-9868.2005.00513.x>.

One degree of freedom contrasts for lm', glm', gls', and geese objects.

This package provides functions for nonlinear regression parameters estimation by algorithms based on Controlled Random Search algorithm. Both functions (crs4hc(), crs4hce()) adapt current search strategy by four heuristics competition. In addition, crs4hce() improves adaptability by adaptive stopping condition.

Allows you to conduct robust correlations on your non-normal data set. The robust correlations included in the package are median-absolute-deviation and median-based correlations. Li, J.C.H. (2022) <doi:10.5964/meth.8467>.

This package provides functions calculating Conley (1999) <doi:10.1016/S0304-4076(98)00084-0> standard errors. The package started by merging and extending multiple packages and other published scripts on this econometric technique. It strongly emphasizes computational optimization. Details are available in the function documentation and in the vignette.