Barnard's unconditional test for 2x2 contingency tables.

US baby names provided by the SSA. This package contains all names used for at least 5 children of either sex.

This package provides a Bayesian variable selection approach using continuous spike and slab prior distributions. The prior choices here are motivated by the shrinking and diffusing priors studied in Narisetty & He (2014) <DOI:10.1214/14-AOS1207>.

Analysis of relative cell type proportions in bulk gene expression data. Provides a well-validated set of brain cell type-specific marker genes derived from multiple types of experiments, as described in McKenzie (2018) <doi:10.1038/s41598-018-27293-5>. For brain tissue data sets, there are marker genes available for astrocytes, endothelial cells, microglia, neurons, oligodendrocytes, and oligodendrocyte precursor cells, derived from each of human, mice, and combination human/mouse data sets. However, if you have access to your own marker genes, the functions can be applied to bulk gene expression data from any tissue. Also implements multiple options for relative cell type proportion estimation using these marker genes, adapting and expanding on approaches from the CellCODE R package described in Chikina (2015) <doi:10.1093/bioinformatics/btv015>. The number of cell type marker genes used in a given analysis can be increased or decreased based on your preferences and the data set. Finally, provides functions to use the estimates to adjust for variability in the relative proportion of cell types across samples prior to downstream analyses.

This package provides some tools for developing and validating prediction models, estimate expected survival of patients and visualize them graphically. Most of the implemented methods are based on penalized regressions such as: the lasso (Tibshirani R (1996)), the elastic net (Zou H et al. (2005) <doi:10.1111/j.1467-9868.2005.00503.x>), the adaptive lasso (Zou H (2006) <doi:10.1198/016214506000000735>), the stability selection (Meinshausen N et al. (2010) <doi:10.1111/j.1467-9868.2010.00740.x>), some extensions of the lasso (Ternes et al. (2016) <doi:10.1002/sim.6927>), some methods for the interaction setting (Ternes N et al. (2016) <doi:10.1002/bimj.201500234>), or others. A function generating simulated survival data set is also provided.

Using numeric or raster data, this package contains functions to calculate: complete water balance, bioclimatic balance, bioclimatic intensities, reports for individual locations, multi-layered rasters for spatial analysis.

This package implements bridge models for nowcasting and forecasting macroeconomic variables by linking high-frequency indicator variables (e.g., monthly data) to low-frequency target variables (e.g., quarterly GDP). Simplifies forecasting and aggregating indicator variables to match the target frequency, enabling timely predictions ahead of official data releases. For more on bridge models, see Baffigi, A., Golinelli, R., & Parigi, G. (2004) <doi:10.1016/S0169-2070(03)00067-0>, Burri (2023) <https://www5.unine.ch/RePEc/ftp/irn/pdfs/WP23-02.pdf> or Schumacher (2016) <doi:10.1016/j.ijforecast.2015.07.004>.

Response surface methods for drug synergy analysis. Available methods include generalized and classical Loewe formulations as well as Highest Single Agent methodology. Response surfaces can be plotted in an interactive 3-D plot and formal statistical tests for presence of synergistic effects are available. Implemented methods and tests are described in the article "BIGL: Biochemically Intuitive Generalized Loewe null model for prediction of the expected combined effect compatible with partial agonism and antagonism" by Koen Van der Borght, Annelies Tourny, Rytis Bagdziunas, Olivier Thas, Maxim Nazarov, Heather Turner, Bie Verbist & Hugo Ceulemans (2017) <doi:10.1038/s41598-017-18068-5>.

Quantile regression with cubic B-splines under monotonicity and convexity constraints using the Karlin-Studden SOCP formulation. The method is described in Abbes (2026) <doi:10.5281/zenodo.17427913>. This R implementation is intended for demonstration and prototyping; all B-spline and polynomial functions have been rewritten for consistency. A faster version written in Python is available at <https://github.com/alexandreabbes/Constrained-Quantile-Regression-with-cubic-splines>.

Create a blended curve from two survival curves, which is particularly useful for survival extrapolation in health technology assessment. The main idea is to mix a flexible model that fits the observed data well with a parametric model that encodes assumptions about long-term survival. The two curves are blended into a single survival curve that is identical to the first model over the range of observed times and gradually approaches the parametric model over the extrapolation period based on a given weight function. This approach allows for the inclusion of external information, such as data from registries or expert opinion, to guide long-term extrapolations, especially when dealing with immature trial data. See Che et al. (2022) <doi:10.1177/0272989X221134545>.

Generates robust confidence intervals for standardized regression coefficients using heteroskedasticity-consistent standard errors for models fitted by lm() as described in Dudgeon (2017) <doi:10.1007/s11336-017-9563-z>. The package can also be used to generate confidence intervals for R-squared, adjusted R-squared, and differences of standardized regression coefficients. A description of the package and code examples are presented in Pesigan, Sun, and Cheung (2023) <doi:10.1080/00273171.2023.2201277>.

High performance principal component analysis routines that operate directly on bigmemory::big.matrix() objects. The package avoids materialising large matrices in memory by streaming data through BLAS and LAPACK kernels and provides helpers to derive scores, loadings, correlations, and contribution diagnostics, including utilities that stream results into bigmemory'-backed matrices for file-based workflows. Additional interfaces expose scalable singular value decomposition, robust PCA, and robust SVD algorithms so that users can explore large matrices while tempering the influence of outliers. Scalable principal component analysis is also implemented, Elgamal, Yabandeh, Aboulnaga, Mustafa, and Hefeeda (2015) <doi:10.1145/2723372.2751520>.

Data Package that includes several examples of chemical and biological data networks, i.e. data graph structured.

Read and process brand.yml YAML files. brand.yml is a simple, portable YAML file that codifies your company's brand guidelines into a format that can be used by Quarto', Shiny and R tooling to create branded outputs. Maintain unified, branded theming for web applications to printed reports to dashboards and presentations with a consistent look and feel.

Simultaneously clusters the Periodontal diseases (PD) patients and their tooth sites after taking the patient- and site-level covariates into consideration. BAREB uses the determinantal point process (DPP) prior to induce diversity among different biclusters to facilitate parsimony and interpretability. Essentially, BAREB is a cluster-wise linear model based on Yuliang (2020) <doi:10.1002/sim.8536>.

This package provides a light-weight object-oriented system with python'-like syntax which supports multiple inheritances and incorporates a python'-like method resolution order.

Disaggregates an observed aggregate price index into sectoral components with a Bayesian state-space model in which the aggregate enters as a genuine observation density rather than as a renormalization identity. A random-walk-with-drift transition in log space (with partial pooling on the drift and the innovation scale) and an estimable cross-sectional concentration produce posterior draws of the sectoral indices with credible intervals, suitable as multiple-imputation input for downstream dynamic models. The Hamiltonian Monte Carlo engine follows Stan (Carpenter et al., 2017) <doi:10.18637/jss.v076.i01>; model comparison uses Pareto Smoothed Importance Sampling Leave-One-Out cross-validation (Vehtari, Gelman and Gabry, 2017) <doi:10.1007/s11222-016-9696-4>. A closed-form linear-Gaussian Kalman/RTS smoother provides an exact, MCMC-free Bayesian alternative for the same aggregate evidence.

This package contains data and code to accompany the book P. Zuccolotto and M. Manisera (2020) Basketball Data Science. Applications with R. CRC Press. ISBN 9781138600799.

This package provides a beginners toolbox to help those in ecology who want to deepen their understanding or utilize Bioacoustics in their work. The package has a number of utilizations from calculating frequency from waveform, performing operations in dB, and determining acoustic range of recorders. The majority of this package is based on key concepts learned from the K. Lisa Yang Center for Conservation Bioacoustics at Cornell University and their associated course: Introduction to Bioacoustics course. More information can be found within the walk through vignettes at <https://github.com/MattyD797/bioSNR/tree/main/vignettes>.

To perform species identification using DNA barcodes.

This package provides a Bayesian smoothing method for post-processing of remote sensing image classification which refines the labelling in a classified image in order to enhance its classification accuracy. Combines pixel-based classification methods with a spatial post-processing method to remove outliers and misclassified pixels.

This package provides a collection of R functions were implemented from published and available analytic solutions for the One-Dimensional Boussinesq Equation (ground-water). In particular, the function "beq.lin()" is the analytic solution of the linearized form of Boussinesq Equation between two different head-based boundary (Dirichlet) conditions; "beq.song" is the non-linear power-series analytic solution of the motion of a wetting front over a dry bedrock (Song at al, 2007, see complete reference on function documentation). Bugs/comments/questions/collaboration of any kind are warmly welcomed.

The function estimates the hazard function non parametrically from a survival object (possibly adjusted for covariates). The smoothed estimate is based on B-splines from the perspective of generalized linear mixed models. Left truncated and right censoring data are allowed. The package is based on the work in Rebora P (2014) <doi:10.32614/RJ-2014-028>.

Perform seasonal adjustment and forecasting of weekly data. The package provides a user-friendly interface for computing seasonally adjusted estimates and forecasts of weekly time series and includes functions for the construction of country-specific prior adjustment variables, as well as diagnostic tools to assess the quality of the adjustments. The methodology is described in more detail in Ginker (2024) <doi:10.13140/RG.2.2.12221.44000>.