This package provides a likelihood-based hypothesis testing approach is implemented for assessing causal mediation. Described in Millstein, Chen, and Breton (2016), <DOI:10.1093/bioinformatics/btw135>, it could be used to test for mediation of a known causal association between a DNA variant, the instrumental variable', and a clinical outcome or phenotype by gene expression or DNA methylation, the potential mediator. Another example would be testing mediation of the effect of a drug on a clinical outcome by the molecular target. The hypothesis test generates a p-value or permutation-based FDR value with confidence intervals to quantify uncertainty in the causal inference. The outcome can be represented by either a continuous or binary variable, the potential mediator is continuous, and the instrumental variable can be continuous or binary and is not limited to a single variable but may be a design matrix representing multiple variables.

Supplies higher-order coordinatized data specification and fluid transform operators that include pivot and anti-pivot as special cases. The methodology is describe in Zumel', 2018, "Fluid data reshaping with cdata'", <https://winvector.github.io/FluidData/FluidDataReshapingWithCdata.html> , <DOI:10.5281/zenodo.1173299> . This package introduces the idea of explicit control table specification of data transforms. Works on in-memory data or on remote data using rquery and SQL database interfaces.

This package provides tools for fitting the copCAR (Hughes, 2015) <DOI:10.1080/10618600.2014.948178> regression model for discrete areal data. Three types of estimation are supported (continuous extension, composite marginal likelihood, and distributional transform), for three types of outcomes (Bernoulli, negative binomial, and Poisson).

We implement causal decomposition analysis using methods proposed by Park, Lee, and Qin (2022) and Park, Kang, and Lee (2023), which provide researchers with multiple-mediator imputation, single-mediator imputation, and product-of-coefficients regression approaches to estimate the initial disparity, disparity reduction, and disparity remaining (<doi:10.1177/00491241211067516>; <doi:10.1177/00811750231183711>). We also implement sensitivity analysis for causal decomposition using R-squared values as sensitivity parameters (Park, Kang, Lee, and Ma, 2023 <doi:10.1515/jci-2022-0031>). Finally, we include individualized causal decomposition and sensitivity analyses proposed by Park, Kang, and Lee (2025+) <doi:10.48550/arXiv.2506.19010>.

This package provides a multi-task learning approach to variable selection regression with highly correlated predictors and sparse effects, based on frequentist statistical inference. It provides statistical evidence to identify which subsets of predictors have non-zero effects on which subsets of response variables, motivated and designed for colocalization analysis across genome-wide association studies (GWAS) and quantitative trait loci (QTL) studies. The ColocBoost model is described in Cao et. al. (2025) <doi:10.1101/2025.04.17.25326042>.

Using polygenic scores (PGS, or PRS/GRS for binary outcomes), this package allows to investigate shared predisposition between different conditions, and do fast association analysis, export plots and views of the PGS distribution using ggplot2 object.

This package contains an administrative-level-1 map of the world. Administrative-level-1 is the generic term for the largest sub-national subdivision of a country. This package was created for use with the choroplethr package.

An interface to the cycle routing/data services provided by CycleStreets', a not-for-profit social enterprise and advocacy organisation. The application programming interfaces (APIs) provided by CycleStreets are documented at (<https://www.cyclestreets.net/api/>). The focus of this package is the journey planning API, which aims to emulate the routes taken by a knowledgeable cyclist. An innovative feature of the routing service of its provision of fastest, quietest and balanced profiles. These represent routes taken to minimise time, avoid traffic and compromise between the two, respectively.

Generates the scripts required to create an Observational Medical Outcomes Partnership (OMOP) Common Data Model (CDM) database and associated documentation for supported database platforms. Leverages the SqlRender package to convert the Data Definition Language (DDL) script written in parameterized Structured Query Language (SQL) to the other supported dialects.

This package provides data science tools for conservation science, including methods for environmental data analysis, humidity calculations, sustainability metrics, engineering calculations, and data visualisation. Supports conservators, scientists, and engineers working with cultural heritage preventive conservation data. The package is motivated by the framework outlined in Cosaert and Beltran et al. (2022) "Tools for the Analysis of Collection Environments" <https://www.getty.edu/conservation/publications_resources/pdf_publications/tools_for_the_analysis_of_collection_environments.html>.

Calculates centrality indices additional to the igraph package centrality functions.

Perform post hoc analysis based on residuals of Pearson's Chi-squared Test for Count Data based on T. Mark Beasley & Randall E. Schumacker (1995) <doi: 10.1080/00220973.1995.9943797>.

Use three methods to estimate parameters from a mediation analysis with a binary misclassified mediator. These methods correct for the problem of "label switching" using Youden's J criteria. A detailed description of the analysis methods is available in Webb and Wells (2024), "Effect estimation in the presence of a misclassified binary mediator" <doi:10.48550/arXiv.2407.06970>.

This package implements clinical tolerance limits (CTL) methodology for assessing agreement between two measurement methods. Estimates the true latent trait using Best Linear Unbiased Predictors (BLUP), models bias and variance components, and calculates overall and conditional agreement probabilities. Provides visualization tools including tolerance limit plots and conditional probability of agreement plots with confidence bands. This package is based on methods described in Taffé (2016) <doi:10.1177/0962280216666667>, Taffé (2019) <doi:10.1177/0962280219844535>, and Stata package Taffé (2025) <doi:10.1177/1536867X251365501>.

This package provides a cascade select widget for usage in Shiny applications. This is useful for selection of hierarchical choices (e.g. continent, country, city). It is taken from the JavaScript library PrimeReact'.

This package provides functions for calculating the conditional power for different models in survival time analysis within randomized clinical trials with two different treatments to be compared and survival as an endpoint.

Simple interpolation methods designed to be used from C code. Supports constant, linear and spline interpolation. An R wrapper is included but this package is primarily designed to be used from C code using LinkingTo'. The spline calculations are classical cubic interpolation, e.g., Forsythe, Malcolm and Moler (1977) <ISBN: 9780131653320>.

Computerized tomography (CT) can be used to assess certain wood properties when wood disks or logs are scanned. Wood density profiles (i.e. variations of wood density from pith to bark) can yield important information used for studies in forest resource assessment, wood quality and dendrochronology studies. The first step consists in transforming grey values from the scan images to density values. The packages then proposes a unique method to automatically locate the pith by combining an adapted Hough Transform method and a one-dimensional edge detector. Tree ring profiles (average ring density, earlywood and latewood density, ring width and percent latewood for each ring) are then obtained.

Solves optimal pairing and matching problems using linear assignment algorithms. Provides implementations of the Hungarian method (Kuhn 1955) <doi:10.1002/nav.3800020109>, Jonker-Volgenant shortest path algorithm (Jonker and Volgenant 1987) <doi:10.1007/BF02278710>, Auction algorithm (Bertsekas 1988) <doi:10.1007/BF02186476>, cost-scaling (Goldberg and Kennedy 1995) <doi:10.1007/BF01585996>, scaling algorithms (Gabow and Tarjan 1989) <doi:10.1137/0218069>, push-relabel (Goldberg and Tarjan 1988) <doi:10.1145/48014.61051>, and Sinkhorn entropy-regularized transport (Cuturi 2013) <doi:10.48550/arxiv.1306.0895>. Designed for matching plots, sites, samples, or any pairwise optimization problem. Supports rectangular matrices, forbidden assignments, data frame inputs, batch solving, k-best solutions, and pixel-level image morphing for visualization. Includes automatic preprocessing with variable health checks, multiple scaling methods (standardized, range, robust), greedy matching algorithms, and comprehensive balance diagnostics for assessing match quality using standardized differences and distribution comparisons.

Computing, comparing, and demonstrating top informative centrality measures within a network. "CINNA: an R/CRAN package to decipher Central Informative Nodes in Network Analysis" provides a comprehensive overview of the package functionality Ashtiani et al. (2018) <doi:10.1093/bioinformatics/bty819>.

This package provides a general test for conditional independence in supervised learning algorithms as proposed by Watson & Wright (2021) <doi:10.1007/s10994-021-06030-6>. Implements a conditional variable importance measure which can be applied to any supervised learning algorithm and loss function. Provides statistical inference procedures without parametric assumptions and applies equally well to continuous and categorical predictors and outcomes.

Read and manipulate Camera Trap Data Packages ('Camtrap DP'). Camtrap DP (<https://camtrap-dp.tdwg.org>) is a data exchange format for camera trap data. With camtrapdp you can read, filter and transform data (including to Darwin Core) before further analysis in e.g. camtraptor or camtrapR'.

Fork of calendR R package to generate ready to print calendars with ggplot2 (see <https://r-coder.com/calendar-plot-r/>) with additional features (backwards compatible). calendRio provides a calendR() function that serves as a drop-in replacement for the upstream version but allows for additional parameters unlocking extra functionality.

This package implements Cragg-Donald (1993) <doi:10.1017/S0266466600007519> and Stock and Yogo (2005) <doi:10.1017/CBO9780511614491.006> tests for weak instruments in R.