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Succinctly and correctly format statistical summaries of various models and tests (F-test, Chi-Sq-test, Fisher-test, T-test, and rank-significance). This package also includes empirical tests, such as Monte Carlo and bootstrap distribution estimates.
Bio-Layer Interferometry (BLI) is a technology to determine the binding kinetics between biomolecules. BLI signals are small and noisy when small molecules are investigated as ligands (analytes). We develop this package to process and analyze the BLI data acquired on Octet Red96 from Fortebio more accurately. Sun Q., Li X., et al (2020) <doi:10.1038/s41467-019-14238-3>. In this new version, we organize the BLI experiment data and analysis methods into a S4 class with self-explaining structure.
Latent space models for multivariate networks (multiplex) estimated via MCMC algorithm. See D Angelo et al. (2018) <arXiv:1803.07166> and D Angelo et al. (2018) <arXiv:1807.03874>.
Simulates correlated multinomial responses conditional on a marginal model specification.
Reimplementation of the svDialogs dialog boxes in Tcl/Tk.
Starting from a Regression Model, it provides a stepwise procedure to select the linear predictor.
Soft-margin support vector machines (SVMs) are a common class of classification models. The training of SVMs usually requires that the data be available all at once in a single batch, however the Stochastic majorization-minimization (SMM) algorithm framework allows for the training of SVMs on streamed data instead Nguyen, Jones & McLachlan(2018)<doi:10.1007/s42081-018-0001-y>. This package utilizes the SMM framework to provide functions for training SVMs with hinge loss, squared-hinge loss, and logistic loss.
An easy-to-use and efficient tool to estimate infectious diseases parameters using serological data. Implemented models include SIR models (basic_sir_model(), static_sir_model(), mseir_model(), sir_subpops_model()), parametric models (polynomial_model(), fp_model()), nonparametric models (lp_model()), semiparametric models (penalized_splines_model()), hierarchical models (hierarchical_bayesian_model()). The package is based on the book "Modeling Infectious Disease Parameters Based on Serological and Social Contact Data: A Modern Statistical Perspective" (Hens, Niel & Shkedy, Ziv & Aerts, Marc & Faes, Christel & Damme, Pierre & Beutels, Philippe., 2013) <doi:10.1007/978-1-4614-4072-7>.
Regression trunk model estimation proposed by Dusseldorp and Meulman (2004) <doi:10.1007/bf02295641> and Dusseldorp, Conversano, Van Os (2010) <doi:10.1198/jcgs.2010.06089>, integrating a regression tree and a multiple regression model.
This package implements S3 classes for storing dates and date-times based on the Jalali calendar. The main design goal of shide is consistency with base R's Date and POSIXct'. It provide features such as: date-time parsing, formatting and arithmetic.
Code and data for modelling and simulation of stochastic kinetic biochemical network models. It contains the code and data associated with the second and third editions of the book Stochastic Modelling for Systems Biology, published by Chapman & Hall/CRC Press.
The complete scripts from the American version of the Office television show in tibble format. Use this package to analyze and have fun with text from the best series of all time.
An implementation of ranked sparsity methods, including penalized regression methods such as the sparsity-ranked lasso, its non-convex alternatives, and elastic net, as well as the sparsity-ranked Bayesian Information Criterion. As described in Peterson and Cavanaugh (2022) <doi:10.1007/s10182-021-00431-7>, ranked sparsity is a philosophy with methods primarily useful for variable selection in the presence of prior informational asymmetry, which occurs in the context of trying to perform variable selection in the presence of interactions and/or polynomials. Ultimately, this package attempts to facilitate dealing with cumbersome interactions and polynomials while not avoiding them entirely. Typically, models selected under ranked sparsity principles will also be more transparent, having fewer falsely selected interactions and polynomials than other methods.
Compiles and displays the available data sets regarding the Italian school system, with a focus on the infrastructural aspects. Input datasets are downloaded from the web, with the aim of updating everything to real time. The functions are divided in four main modules, namely Get', to scrape raw data from the web Util', various utilities needed to process raw data Group', to aggregate data at the municipality or province level Map', to visualize the output datasets.
This package provides tools to simulate and analyse datasets of social interactions between individuals using hierarchical Bayesian models implemented in Stan. Model fitting is performed via the rstan package. Users can generate realistic interaction data where individual phenotypes influence and respond to those of their partners, with control over sampling design parameters such as the number of individuals, partners, and repeated dyads. The simulation framework allows flexible control over variation and correlation in mean trait values, social responsiveness, and social impact, making it suitable for research on interacting phenotypes and on direct and indirect genetic effects ('DGEs and IGEs'). The package also includes functions to fit and compare alternative models of social effects, including impactâ responsiveness, varianceâ partitioning, and trait-based models, and to summarise model performance in terms of bias and dispersion. For a more detailed description of the available models and impactâ responsiveness, see the accompanying preprint Wijnhorst et al. (2025) <doi:10.32942/X2F65M>.
This software is useful for loading .fasta or .gbk files, and for retrieving sequences from GenBank dataset <https://www.ncbi.nlm.nih.gov/genbank/>. This package allows to detect differences or asymmetries based on nucleotide composition by using local linear kernel smoothers. Also, it is possible to draw inference about critical points (i. e. maximum or minimum points) related with the derivative curves. Additionally, bootstrap methods have been used for estimating confidence intervals and speed computational techniques (binning techniques) have been implemented in seq2R'.
The number of studies involving correlated traits and the availability of tools to handle this type of data has increased considerably in the last decade. With such a demand, we need tools for testing hypotheses related to single and multi-trait (correlated) phenotypes based on many genetic settings. Thus, we implemented various options for simulation of pleiotropy and Linkage Disequilibrium under additive, dominance and epistatic models. The simulation currently takes a marker data set as an input and then uses it for simulating multiple traits as described in Fernandes and Lipka (2020) <doi:10.1186/s12859-020-03804-y>.
This package provides a wrapper to access data from the SeeClickFix web API for R. SeeClickFix is a central platform employed by many cities that allows citizens to request their city's services. This package creates several functions to work with all the built-in calls to the SeeClickFix API. Allows users to download service request data from numerous locations in easy-to-use dataframe format manipulable in standard R functions.
Deals with Young tableaux (field of combinatorics). For standard Young tabeaux, performs enumeration, counting, random generation, the Robinson-Schensted correspondence, and conversion to and from paths on the Young lattice. Also performs enumeration and counting of semistandard Young tableaux, enumeration of skew semistandard Young tableaux, enumeration of Gelfand-Tsetlin patterns, and computation of Kostka numbers.
An overall test for seasonality of a given time series in addition to a set of individual seasonality tests as described by Ollech and Webel (forthcoming): An overall seasonality test. Bundesbank Discussion Paper.
Downloads and tidies the San Francisco Public Utilities Commission Beach Water Quality Monitoring Program data. Data sets can be downloaded per beach, or the raw data can be downloaded. See <https://sfwater.org/cfapps/lims/beachmain1.cfm>.
Multi-stage selection is practiced in numerous fields of life and social sciences and particularly in breeding. A special characteristic of multi-stage selection is that candidates are evaluated in successive stages with increasing intensity and effort, and only a fraction of the superior candidates is selected and promoted to the next stage. For the optimum design of such selection programs, the selection gain plays a crucial role. It can be calculated by integration of a truncated multivariate normal (MVN) distribution. While mathematical formulas for calculating the selection gain and the variance among selected candidates were developed long time ago, solutions for numerical calculation were not available. This package can also be used for optimizing multi-stage selection programs for a given total budget and different costs of evaluating the candidates in each stage.
Simultaneously infers state-dependent diversification across two or more states of a single or multiple traits while accounting for the role of a possible concealed trait. See Herrera-Alsina et al. (2019) <doi:10.1093/sysbio/syy057>.
Procedure to optimally split a dataset for training and testing. SPlit is based on the method of support points, which is independent of modeling methods. Please see Joseph and Vakayil (2021) <doi:10.1080/00401706.2021.1921037> for details. This work is supported by U.S. National Science Foundation grant DMREF-1921873.