Bayesian dynamic borrowing with covariate adjustment via inverse probability weighting for simulations and data analyses in clinical trials. This makes it easy to use propensity score methods to balance covariate distributions between external and internal data. This methodology based on Psioda et al (2025) <doi:10.1080/10543406.2025.2489285>.

Search and download data from the Swiss Federal Statistical Office (BFS) APIs <https://www.bfs.admin.ch/>.

Bayesian estimations of a covariance matrix for multivariate normal data. Assumes that the covariance matrix is sparse or band matrix and positive-definite. Methods implemented include the beta-mixture shrinkage prior (Lee et al. (2022) <doi:10.1016/j.jmva.2022.105067>), screened beta-mixture prior (Lee et al. (2024) <doi:10.1214/24-BA1495>), and post-processed posteriors for banded and sparse covariances (Lee et al. (2023) <doi:10.1214/22-BA1333>; Lee and Lee (2023) <doi:10.1016/j.jeconom.2023.105475>). This software has been developed using funding supported by Basic Science Research Program through the National Research Foundation of Korea ('NRF') funded by the Ministry of Education ('RS-2023-00211979', NRF-2022R1A5A7033499', NRF-2020R1A4A1018207 and NRF-2020R1C1C1A01013338').

Bayesian methods for predicting the calendar time at which a target number of events is reached in clinical trials. The methodology applies to both blinded and unblinded settings and jointly models enrollment, event-time, and censoring processes. The package provides tools for trial data simulation, model fitting using Stan via the rstan interface, and event time prediction under a wide range of trial designs, including varying sample sizes, enrollment patterns, treatment effects, and event or censoring time distributions. The package is intended to support interim monitoring, operational planning, and decision-making in clinical trial development. Methods are described in Fu et al. (2025) <doi:10.1002/sim.70310>.

The bullwhipgame is an educational game that has as purpose the illustration and exploration of the bullwhip effect,i.e, the increase in demand variability along the supply chain. Marchena Marlene (2010) <arXiv:1009.3977>.

Utilities for Bratteli graphs. A tree is an example of a Bratteli graph. The package provides a function which generates a LaTeX file that renders the given Bratteli graph. It also provides functions to compute the dimensions of the vertices, the intrinsic kernels and the intrinsic distances. Intrinsic kernels and distances were introduced by Vershik (2014) <doi:10.1007/s10958-014-1958-0>.

Tool for quantitative research in scientometrics and bibliometrics. It implements the comprehensive workflow for science mapping analysis proposed in Aria M. and Cuccurullo C. (2017) <doi:10.1016/j.joi.2017.08.007>. bibliometrix provides various routines for importing bibliographic data from SCOPUS', Clarivate Analytics Web of Science (<https://www.webofknowledge.com/>), Digital Science Dimensions (<https://www.dimensions.ai/>), OpenAlex (<https://openalex.org/>), Cochrane Library (<https://www.cochranelibrary.com/>), Lens (<https://lens.org>), and PubMed (<https://pubmed.ncbi.nlm.nih.gov/>) databases, performing bibliometric analysis and building networks for co-citation, coupling, scientific collaboration and co-word analysis.

This package provides a two-step Bayesian approach for mode inference following Cross, Hoogerheide, Labonne and van Dijk (2024) <doi:10.1016/j.econlet.2024.111579>). First, a mixture distribution is fitted on the data using a sparse finite mixture (SFM) Markov chain Monte Carlo (MCMC) algorithm. The number of mixture components does not have to be known; the size of the mixture is estimated endogenously through the SFM approach. Second, the modes of the estimated mixture at each MCMC draw are retrieved using algorithms specifically tailored for mode detection. These estimates are then used to construct posterior probabilities for the number of modes, their locations and uncertainties, providing a powerful tool for mode inference.

Implementation of the bunching estimator for kinks and notches. Allows for flexible estimation of counterfactual (e.g. controlling for round number bunching, accounting for other bunching masses within bunching window, fixing bunching point to be minimum, maximum or median value in its bin, etc.). It produces publication-ready plots in the style followed since Chetty et al. (2011) <doi:10.1093/qje/qjr013>, with lots of functionality to set plot options.

This package provides functions for behavior genetics analysis, including variance component model identification [Hunter et al. (2021) <doi:10.1007/s10519-021-10055-x>], calculation of relatedness coefficients using path-tracing methods [Wright (1922) <doi:10.1086/279872>; McArdle & McDonald (1984) <doi:10.1111/j.2044-8317.1984.tb00802.x>], inference of relatedness, pedigree conversion, and simulation of multi-generational family data [Lyu et al. (2024) <doi:10.1101/2024.12.19.629449>]. For a full overview, see [Garrison et al. (2024) <doi:10.21105/joss.06203>].

Fit Bayesian Regression Additive Trees (BART) models to select true confounders from a large set of potential confounders and to estimate average treatment effect. For more information, see Kim et al. (2023) <doi:10.1111/biom.13833>.

This package provides methods for detecting and visualizing cladogenic shifts in multivariate trait data on phylogenies. Implements penalized-likelihood multivariate generalized least squares models, enabling analyses of high-dimensional trait datasets and large trees via searchOptimalConfiguration(). Includes a greedy step-wise shift-search algorithm following approaches developed in Smith et al. (2023) <doi:10.1111/nph.19099> and Berv et al. (2024) <doi:10.1126/sciadv.adp0114>. Methods build on multivariate GLS approaches described in Clavel et al. (2019) <doi:10.1093/sysbio/syy045> and implemented in the mvgls() function from the mvMORPH package. Documentation and vignettes are available at <https://jakeberv.com/bifrost/>, including the introductory vignette at <https://jakeberv.com/bifrost/articles/jaw-shape-vignette.html>.

The method models RNA-seq reads using a mixture of 3 beta-binomial distributions to generate posterior probabilities for genotyping bi-allelic single nucleotide polymorphisms. Elena Vigorito, Anne Barton, Costantino Pitzalis, Myles J. Lewis and Chris Wallace (2023) <doi:10.1093/bioinformatics/btad393> "BBmix: a Bayesian beta-binomial mixture model for accurate genotyping from RNA-sequencing.".

This package provides methods to estimate optimal dynamic treatment regimes using Bayesian likelihood-based regression approach as described in Yu, W., & Bondell, H. D. (2023) <doi:10.1093/jrsssb/qkad016> Uses backward induction and dynamic programming theory for computing expected values. Offers options for future parallel computing.

This package implements the Bayesian FDR control described by Newton et al. (2004), <doi:10.1093/biostatistics/5.2.155>. Allows optimisation and visualisation of expected error rates based on tail posterior probability tests. Based on code written by Catalina Vallejos for BASiCS, see Beyond comparisons of means: understanding changes in gene expression at the single-cell level Vallejos et al. (2016) <doi:10.1186/s13059-016-0930-3>.

Allows the user to apply the Bayes Linear approach to finite population with the Simple Random Sampling - BLE_SRS() - and the Stratified Simple Random Sampling design - BLE_SSRS() - (both without replacement), to the Ratio estimator (using auxiliary information) - BLE_Ratio() - and to categorical data - BLE_Categorical(). The Bayes linear estimation approach is applied to a general linear regression model for finite population prediction in BLE_Reg() and it is also possible to achieve the design based estimators using vague prior distributions. Based on Gonçalves, K.C.M, Moura, F.A.S and Migon, H.S.(2014) <https://www150.statcan.gc.ca/n1/en/catalogue/12-001-X201400111886>.

This package provides a Bayesian, global planktic foraminifera core top calibration to modern sea-surface temperatures. Includes four calibration models, considering species-specific calibration parameters and seasonality.

This package contains tools to fit both predictive and prognostic biomarker effects using biomarker threshold models and continuous threshold models. Evaluate the treatment effect, biomarker effect and treatment-biomarker interaction using probability index measurement. Test for treatment-biomarker interaction using residual bootstrap method.

Routine for fitting regression models for binary rare events with linear and nonlinear covariate effects when using the quantile function of the Generalized Extreme Value random variable.

This package provides a Bayesian latent space model for complex networks, either weighted or unweighted. Given an observed input graph, the estimates for the latent coordinates of the nodes are obtained through a Bayesian MCMC algorithm. The overall likelihood of the graph depends on a fundamental probability equation, which is defined so that ties are more likely to exist between nodes whose latent space coordinates are close. The package is mainly based on the model by Hoff, Raftery and Handcock (2002) <doi:10.1198/016214502388618906> and contains some extra features (e.g., removal of the Procrustean step, weights implemented as coefficients of the latent distances, 3D plots). The original code related to the above model was retrieved from <https://www.stat.washington.edu/people/pdhoff/Code/hoff_raftery_handcock_2002_jasa/>. Users can inspect the MCMC simulation, create and customize insightful graphical representations or apply clustering techniques.

Facilitates retrieval, transformation and analysis of the data from the Barcode of Life Data Systems (BOLD) database <https://boldsystems.org/>. This package allows both public and private user data to be easily downloaded into the R environment using a variety of inputs such as: IDs (processid, sampleid), BINs, dataset codes, project codes, taxonomy, geography etc. It provides frictionless data conversion into formats compatible with other R-packages and third-party tools, as well as functions for sequence alignment & clustering, biodiversity analysis and spatial mapping.

This package provides Partial least squares Regression and various regular, sparse or kernel, techniques for fitting Cox models for big data. Provides a Partial Least Squares (PLS) algorithm adapted to Cox proportional hazards models that works with bigmemory matrices without loading the entire dataset in memory. Also implements a gradient-descent based solver for Cox proportional hazards models that works directly on bigmemory matrices. Bertrand and Maumy (2023) <https://hal.science/hal-05352069>, and <https://hal.science/hal-05352061> highlighted fitting and cross-validating PLS-based Cox models to censored big data.

Creating, rendering and writing BPMN diagrams <https://www.bpmn.org/>. Functionalities can be used to visualize and export BPMN diagrams created using the pm4py and bupaRminer packages. Part of the bupaR ecosystem.

Calculates B-value and empirical equivalence bound. B-value is defined as the maximum magnitude of a confidence interval; and the empirical equivalence bound is the minimum B-value at a certain level. A new two-stage procedure for hypothesis testing is proposed, where the first stage is conventional hypothesis testing and the second is an equivalence testing procedure using the introduced empirical equivalence bound. See Zhao et al. (2019) "B-Value and Empirical Equivalence Bound: A New Procedure of Hypothesis Testing" <arXiv:1912.13084> for details.