This package provides a new practical method to evaluate whether relationships between two sets of high-dimensional variables are different or not across two conditions. Song, H. and Wu, M.C. (2023) <arXiv:2307.15268>.

The number of clusters (k) is needed to start all the partitioning clustering algorithms. An optimal value of this input argument is widely determined by using some internal validity indices. Since most of the existing internal indices suggest a k value which is computed from the clustering results after several runs of a clustering algorithm they are computationally expensive. On the contrary, the package kpeaks enables to estimate k before running any clustering algorithm. It is based on a simple novel technique using the descriptive statistics of peak counts of the features in a data set.

This package implements the Known Sub-Sequence Algorithm <doi:10.1016/j.aaf.2021.12.013>, which helps to automatically identify and validate the best method for missing data imputation in a time series. Supports the comparison of multiple state-of-the-art algorithms.

Using this package you can combine known kinase substrate relationships with experimental data and determine active kinases and their substrates.

The K-sample omnibus non-proportional hazards (KONP) tests are powerful non-parametric tests for comparing K (>=2) hazard functions based on right-censored data (Gorfine, Schlesinger and Hsu, 2020, <doi:10.1177/0962280220907355>). These tests are consistent against any differences between the hazard functions of the groups. The KONP tests are often more powerful than other existing tests, especially under non-proportional hazard functions.

Various tools and data sets that support the study of kanji, including their morphology, decomposition and concepts of distance and similarity between them.

Assign and listen to keyboard shortcuts in shiny using the Mousetrap Javascript library.

Used to create dynamic, interactive D3.js based parallel coordinates and principal component plots in R'. The plots make visualizing k-means or other clusters simple and informative.

Convert latex math expressions to HTML and MathML for use in markdown documents or package manual pages. The rendering is done in R using the V8 engine (i.e. server-side), which eliminates the need for embedding the MathJax library into your web pages. In addition a math-to-rd wrapper is provided to automatically render beautiful math in R documentation files.

Optimized for handling complex datasets in environmental and ecological research, this package offers functionality that is not fully met by general-purpose packages. It provides two key functions, summarize_data()', which summarizes datasets, and plot_means()', which creates plots with error bars. The plot_means() function incorporates error bars by default, allowing quick visualization of uncertainties, crucial in ecological studies. It also streamlines workflows for grouped datasets (e.g., by species or treatment), making it particularly user-friendly and reducing the complexity and time required for data summarization and visualization.

Solves kernel ridge regression, within the the mixed model framework, for the linear, polynomial, Gaussian, Laplacian and ANOVA kernels. The model components (i.e. fixed and random effects) and variance parameters are estimated using the expectation-maximization (EM) algorithm. All the estimated components and parameters, e.g. BLUP of dual variables and BLUP of random predictor effects for the linear kernel (also known as RR-BLUP), are available. The kernel ridge mixed model (KRMM) is described in Jacquin L, Cao T-V and Ahmadi N (2016) A Unified and Comprehensible View of Parametric and Kernel Methods for Genomic Prediction with Application to Rice. Front. Genet. 7:145. <doi:10.3389/fgene.2016.00145>.

This package provides a multi-purpose and flexible k-meric enrichment analysis software. kmeRtone measures the enrichment of k-mers by comparing the population of k-mers in the case loci with a carefully devised internal negative control group, consisting of k-mers from regions close to, yet sufficiently distant from, the case loci to mitigate any potential sequencing bias. This method effectively captures both the local sequencing variations and broader sequence influences, while also correcting for potential biases, thereby ensuring more accurate analysis. The core functionality of kmeRtone is the SCORE() function, which calculates the susceptibility scores for k-mers in case and control regions. Case regions are defined by the genomic coordinates provided in a file by the user and the control regions can be constructed relative to the case regions or provided directly. The k-meric susceptibility scores are calculated by using a one-proportion z-statistic. kmeRtone is highly flexible by allowing users to also specify their target k-mer patterns and quantify the corresponding k-mer enrichment scores in the context of these patterns, allowing for a more comprehensive approach to understanding the functional implications of specific DNA sequences on a genomic scale (e.g., CT motifs upon UV radiation damage). Adib A. Abdullah, Patrick Pflughaupt, Claudia Feng, Aleksandr B. Sahakyan (2024) Bioinformatics (submitted).

Implementation of Discrete Symmetric Optimal Kernel for estimating count data distributions, as described by T. Senga Kiessé and G. Durrieu (2024) <doi:10.1016/j.spl.2024.110078>.The nonparametric estimator using the discrete symmetric optimal kernel was illustrated on simulated data sets and a real-word data set included in the package, in comparison with two other discrete symmetric kernels.

This package provides functions for identification of putative causal loci in whole-genome sequencing data. The functions allow genome-wide association scan. It also includes an efficient knockoff generator for genetic data.

Kernel functions for diverse types of data (including, but not restricted to: nonnegative and real vectors, real matrices, categorical and ordinal variables, sets, strings), plus other utilities like kernel similarity, kernel Principal Components Analysis (PCA) and features importance for Support Vector Machines (SVMs), which expand other R packages like kernlab'.

Efficient implementation of permutation tests for keyword analysis in corpus linguistics as described in Mildenberger (2023) <arXiv:2308.13383>.

Interface to Keras <https://keras.io>, a high-level neural networks API'. Keras was developed with a focus on enabling fast experimentation, supports both convolution based networks and recurrent networks (as well as combinations of the two), and runs seamlessly on both CPU and GPU devices.

Routines to handle family data with a pedigree object. The initial purpose was to create correlation structures that describe family relationships such as kinship and identity-by-descent, which can be used to model family data in mixed effects models, such as in the coxme function. Also includes a tool for pedigree drawing which is focused on producing compact layouts without intervention. Recent additions include utilities to trim the pedigree object with various criteria, and kinship for the X chromosome.

This package provides data for Kaya identity variables (population, gross domestic product, primary energy consumption, and energy-related CO2 emissions) for the world and for individual nations, and utility functions for looking up data, plotting trends of Kaya variables, and plotting the fuel mix for a given country or region. The Kaya identity (Yoichi Kaya and Keiichi Yokobori, "Environment, Energy, and Economy: Strategies for Sustainability" (United Nations University Press, 1998) and <https://en.wikipedia.org/wiki/Kaya_identity>) expresses a nation's or region's greenhouse gas emissions in terms of its population, per-capita Gross Domestic Product, the energy intensity of its economy, and the carbon-intensity of its energy supply.

Allows analyzing time series representing two-dimensional movements. It accepts a data frame with a time (t), horizontal (x) and vertical (y) coordinate as columns, and returns several dynamical properties such as speed, acceleration or curvature.

This package provides a shiny application for forensic kinship testing, based on the pedsuite R packages. KLINK is closely aligned with the (non-R) software Familias and FamLink', but offers several unique features, including visualisations and automated report generation. The calculation of likelihood ratios supports pairs of linked markers, and all common mutation models.

Fits keyword assisted topic models (keyATM) using collapsed Gibbs samplers. The keyATM combines the latent dirichlet allocation (LDA) models with a small number of keywords selected by researchers in order to improve the interpretability and topic classification of the LDA. The keyATM can also incorporate covariates and directly model time trends. The keyATM is proposed in Eshima, Imai, and Sasaki (2024) <doi:10.1111/ajps.12779>.

Criteria and algorithms for sequentially estimating level sets of a multivariate numerical function, possibly observed with noise.

Retrieve data from kintone (<https://www.kintone.com/>) via its API. kintone is an enterprise application platform.