Spatio-temporal data have become increasingly popular in many research fields. Such data often have complex structures that are difficult to describe and estimate. This package provides reliable tools for modeling complicated spatio-temporal data. It also includes tools of online process monitoring to detect possible change-points in a spatio-temporal process over time. More specifically, the package implements the spatio-temporal mean estimation procedure described in Yang and Qiu (2018) <doi:10.1002/sim.7622>, the spatio-temporal covariance estimation procedure discussed in Yang and Qiu (2019) <doi:10.1002/sim.8315>, the three-step method for the joint estimation of spatio-temporal mean and covariance functions suggested by Yang and Qiu (2022) <doi:10.1007/s10463-021-00787-2>, the spatio-temporal disease surveillance method discussed in Qiu and Yang (2021) <doi:10.1002/sim.9150> that can accommodate the covariate effect, the spatial-LASSO-based process monitoring method proposed by Qiu and Yang (2023) <doi:10.1080/00224065.2022.2081104>, and the online spatio-temporal disease surveillance method described in Yang and Qiu (2020) <doi:10.1080/24725854.2019.1696496>.

The user has the option to utilize the two-dimensional density estimation techniques called smoothed density published by Eilers and Goeman (2004) <doi:10.1093/bioinformatics/btg454>, and pareto density which was evaluated for univariate data by Thrun, Gehlert and Ultsch, 2020 <doi:10.1371/journal.pone.0238835>. Moreover, it provides visualizations of the density estimation in the form of two-dimensional scatter plots in which the points are color-coded based on increasing density. Colors are defined by the one-dimensional clustering technique called 1D distribution cluster algorithm (DDCAL) published by Lux and Rinderle-Ma (2023) <doi:10.1007/s00357-022-09428-6>.

It allows to quickly perform permutation-based closed testing by sum-based global tests, and construct lower confidence bounds for the TDP, simultaneously over all subsets of hypotheses. As a main feature, it produces simultaneous lower confidence bounds for the proportion of active voxels in different clusters for fMRI cluster analysis. Details may be found in Vesely, Finos, and Goeman (2020) <arXiv:2102.11759>.

Provide various functions and tools to help fit models for estimating treatment effects in stepped wedge cluster randomized trials. Implements methods described in Kenny, Voldal, Xia, and Heagerty (2022) "Analysis of stepped wedge cluster randomized trials in the presence of a time-varying treatment effect", <doi:10.1002/sim.9511>.

Computes the Exposure-At-Default based on the standardized approach of CRR2 (SA-CCR). The simplified version of SA-CCR has been included, as well as the OEM methodology. Multiple trade types of all the five major asset classes are being supported including the Other Exposure and, given the inheritance- based structure of the application, the addition of further trade types is straightforward. The application returns a list of trees per Counterparty and CSA after automatically separating the trades based on the Counterparty, the CSAs, the hedging sets, the netting sets and the risk factors. The basis and volatility transactions are also identified and treated in specific hedging sets whereby the corresponding penalty factors are applied. All the examples appearing on the regulatory papers (both for the margined and the unmargined workflow) have been implemented including the latest CRR2 developments.

An implementation of feature selection, weighting and ranking via simultaneous perturbation stochastic approximation (SPSA). The SPSA-FSR algorithm searches for a locally optimal set of features that yield the best predictive performance using some error measures such as mean squared error (for regression problems) and accuracy rate (for classification problems).

Various functions for creating spherical coordinate system plots via extensions to rgl.

Fit design-based linear and logistic elastic nets with complex survey data considering the sampling design when defining training and test sets using replicate weights. Methods implemented in this package are described in: A. Iparragirre, T. Lumley, I. Barrio, I. Arostegui (2024) <doi:10.1002/sta4.578>.

Computes the entire solution paths for Support Vector Regression(SVR) with respect to the regularization parameter, lambda and epsilon in epsilon-intensive loss function, efficiently. We call each path algorithm svrpath and epspath. See Wang, G. et al (2008) <doi:10.1109/TNN.2008.2002077> for details regarding the method.

Simulation tools for closed-loop simulation are provided for the MSEtool operating model to inform data-rich fisheries. SAMtool provides a conditioning model, assessment models of varying complexity with standardized reporting, model-based management procedures, and diagnostic tools for evaluating assessments inside closed-loop simulation.

Calculates the power and sample size based on the difference in Restricted Mean Survival Time.

Implementation of analytical models for estimating streamflow depletion due to groundwater pumping, and other related tools. Functions are broadly split into two groups: (1) analytical streamflow depletion models, which estimate streamflow depletion for a single stream reach resulting from groundwater pumping; and (2) depletion apportionment equations, which distribute estimated streamflow depletion among multiple stream reaches within a stream network. See Zipper et al. (2018) <doi:10.1029/2018WR022707> for more information on depletion apportionment equations and Zipper et al. (2019) <doi:10.1029/2018WR024403> for more information on analytical depletion functions, which combine analytical models and depletion apportionment equations.

By calling the SimpleTex <https://simpletex.cn/> open API implements text and mathematical formula recognition on the image, and the output formula can be used directly with Markdown and LaTeX'.

Highest posterior model is widely accepted as a good model among available models. In terms of variable selection highest posterior model is often the true model. Our stochastic search process SAHPM based on simulated annealing maximization method tries to find the highest posterior model by maximizing the model space with respect to the posterior probabilities of the models. This package currently contains the SAHPM method only for linear models. The codes for GLM will be added in future.

Monitoring reporting rates of subject-level clinical events (e.g. adverse events, protocol deviations) reported by clinical trial sites is an important aspect of risk-based quality monitoring strategy. Sites that are under-reporting or over-reporting events can be detected using bootstrap simulations during which patients are redistributed between sites. Site-specific distributions of event reporting rates are generated that are used to assign probabilities to the observed reporting rates. (Koneswarakantha 2024 <doi:10.1007/s43441-024-00631-8>).

This package provides a graphical user interface for cross-sectional network modeling with the statnet software suite <https://github.com/statnet>.

Quasi-Monte-Carlo algorithm for systematic generation of shock scenarios from an arbitrary multivariate elliptical distribution. The algorithm selects a systematic mesh of arbitrary fineness that approximately evenly covers an isoprobability ellipsoid in d dimensions (Flood, Mark D. & Korenko, George G. (2013) <doi:10.1080/14697688.2014.926018>). This package is the R analogy to the Matlab code published by Flood & Korenko in above-mentioned paper.

Adds support for R startup configuration via .Renviron.d and .Rprofile.d directories in addition to .Renviron and .Rprofile files. This makes it possible to keep private / secret environment variables separate from other environment variables. It also makes it easier to share specific startup settings by simply copying a file to a directory.

This package provides an R interface to the sparseLM C library for large-scale nonlinear least squares problems with arbitrarily sparse Jacobians. The underlying solver implements a sparse variant of the Levenberg-Marquardt algorithm for minimizing sum-of-squares objective functions, supports user-supplied analytic Jacobians or finite-difference approximation, and is designed to exploit sparsity for improved memory use and performance. This package exposes the solver in R and uses sparse matrix classes and the CHOLMOD sparse Cholesky factorization routines through the Matrix package interface. Methods from the C library are described in Lourakis (2010) <doi:10.1007/978-3-642-15552-9_4>.

The saemix package implements the Stochastic Approximation EM algorithm for parameter estimation in (non)linear mixed effects models. It (i) computes the maximum likelihood estimator of the population parameters, without any approximation of the model (linearisation, quadrature approximation,...), using the Stochastic Approximation Expectation Maximization (SAEM) algorithm, (ii) provides standard errors for the maximum likelihood estimator (iii) estimates the conditional modes, the conditional means and the conditional standard deviations of the individual parameters, using the Hastings-Metropolis algorithm (see Comets et al. (2017) <doi:10.18637/jss.v080.i03>). Many applications of SAEM in agronomy, animal breeding and PKPD analysis have been published by members of the Monolix group. The full PDF documentation for the package including references about the algorithm and examples can be downloaded on the github of the IAME research institute for saemix': <https://github.com/iame-researchCenter/saemix/blob/7638e1b09ccb01cdff173068e01c266e906f76eb/docsaem.pdf>.

For surface energy models and estimation of solar positions and components with varying topography, time and locations. The functions calculate solar top-of-atmosphere, open, diffuse and direct components, atmospheric transmittance and diffuse factors, day length, sunrise and sunset, solar azimuth, zenith, altitude, incidence, and hour angles, earth declination angle, equation of time, and solar constant. Details about the methods and equations are explained in Seyednasrollah, Bijan, Mukesh Kumar, and Timothy E. Link. On the role of vegetation density on net snow cover radiation at the forest floor. Journal of Geophysical Research: Atmospheres 118.15 (2013): 8359-8374, <doi:10.1002/jgrd.50575>.

For biparental, three and four-way crosses Identity by Descent (IBD) probabilities can be calculated using Hidden Markov Models and inheritance vectors following Lander and Green (<https://www.jstor.org/stable/29713>) and Huang (<doi:10.1073/pnas.1100465108>). One of a series of statistical genetic packages for streamlining the analysis of typical plant breeding experiments developed by Biometris.

This package provides a system that computes metrics to assess the segmentation accuracy of geospatial data. These metrics calculate the discrepancy between segmented and reference objects, and indicate the segmentation accuracy. For more details on choosing evaluation metrics, we suggest seeing Costa et al. (2018) <doi:10.1016/j.rse.2017.11.024> and Jozdani et al. (2020) <doi:10.1016/j.isprsjprs.2020.01.002>.

Store persistent and synchronized data from shiny inputs within the browser. Refresh shiny applications and preserve user-inputs over multiple sessions. A database-like storage format is implemented using Dexie.js <https://dexie.org>, a minimal wrapper for IndexedDB'. Transfer browser link parameters to shiny input or output values. Store app visitor views, likes and followers.