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SOHPIE (pronounced as SOFIE) is a novel pseudo-value regression approach for differential co-abundance network analysis of microbiome data, which can include additional clinical covariate in the model. The full methodological details can be found in Ahn S and Datta S (2023) <arXiv:2303.13702v1>.
These are miscellaneous functions that I find useful for my research and teaching. The contents include themes for plots, functions for simulating quantities of interest from regression models, functions for simulating various forms of fake data for instructional/research purposes, and many more. All told, the functions provided here are broadly useful for data organization, data presentation, data recoding, and data simulation.
Package performs Cox regression and survival distribution function estimation when the survival times are subject to double truncation. In case that the survival and truncation times are quasi-independent, the estimation procedure for each method involves inverse probability weighting, where the weights correspond to the inverse of the selection probabilities and are estimated using the survival times and truncation times only. A test for checking this independence assumption is also included in this package. The functions available in this package for Cox regression, survival distribution function estimation, and testing independence under double truncation are based on the following methods, respectively: Rennert and Xie (2018) <doi:10.1111/biom.12809>, Shen (2010) <doi:10.1007/s10463-008-0192-2>, Martin and Betensky (2005) <doi:10.1198/016214504000001538>. When the survival times are dependent on at least one of the truncation times, an EM algorithm is employed to obtain point estimates for the regression coefficients. The standard errors are calculated using the bootstrap method. See Rennert and Xie (2022) <doi:10.1111/biom.13451>. Both the independent and dependent cases assume no censoring is present in the data. Please contact Lior Rennert <liorr@clemson.edu> for questions regarding function coxDT and Yidan Shi <yidan.shi@pennmedicine.upenn.edu> for questions regarding function coxDTdep.
This package provides a classification framework to use expression patterns of pathways as features to identify similarity between biological samples. It provides a new measure for quantifying similarity between expression patterns of pathways.
The skew logistic distribution is a quantile-defined generalisation of the logistic distribution (van Staden and King 2015). Provides random numbers, quantiles, probabilities, densities and density quantiles for the distribution. It provides Quantile-Quantile plots and method of L-Moments estimation (including asymptotic standard errors) for the distribution.
This htmlwidget provides pan and zoom interactivity to R graphics, including base', lattice', and ggplot2'. The interactivity is provided through the svg-pan-zoom.js library. Various options to the widget can tailor the pan and zoom experience to nearly any user desire.
This package provides a collection of functions to perform Detrended Fluctuation Analysis (DFA exponent), GUEDES et al. (2019) <doi:10.1016/j.physa.2019.04.132> , Detrended cross-correlation coefficient (RHODCCA), GUEDES & ZEBENDE (2019) <doi:10.1016/j.physa.2019.121286>, DMCA cross-correlation coefficient and Detrended multiple cross-correlation coefficient (DMC), GUEDES & SILVA-FILHO & ZEBENDE (2018) <doi:10.1016/j.physa.2021.125990>, both with sliding windows approach.
This package provides data about the Star Wars movie franchise in a set of relational tables or as a complete DuckDB database. All data was collected from the open source Star Wars API.
Selection index is one of the efficient and acurrate method for selection of animals. This package is useful for construction of selection indices. It uses mixed and random model least squares analysis to estimate the heritability of traits and genetic correlation between traits. The package uses the sire model as it is considered as random effect. The genetic and phenotypic (co)variances along with the relative economic values are used to construct the selection index for any number of traits. It also estimates the accuracy of the index and the genetic gain expected for different traits. Fisher (1936) <doi:10.1111/j.1469-1809.1936.tb02137.x>.
This package provides infrastructure functionalities such as missing value treatment, information value calculation, GINI calculation etc. which are used for developing a traditional credit scorecard as well as a machine learning based model. The functionalities defined are standard steps for any credit underwriting scorecard development, extensively used in financial domain.
This package contains functions and datasets for math taught in school. A main focus is set to prime-calculation.
We build an Susceptible-Infectious-Recovered (SIR) model where the rate of infection is the sum of the household rate and the community rate. We estimate the posterior distribution of the parameters using the Metropolis algorithm. Further details may be found in: F Scott Dahlgren, Ivo M Foppa, Melissa S Stockwell, Celibell Y Vargas, Philip LaRussa, Carrie Reed (2021) "Household transmission of influenza A and B within a prospective cohort during the 2013-2014 and 2014-2015 seasons" <doi:10.1002/sim.9181>.
Simulate and plot general experimental crosses. The focus is on simulating genotypes with an aim towards flexibility rather than speed. Meiosis is simulated following the Stahl model, in which chiasma locations are the superposition of two processes: a proportion p coming from a process exhibiting no interference, and the remainder coming from a process following the chi-square model.
Use of Knock Out and Round Robin Techniques in preparing tournament fixtures as discussed in the Book Health and Physical Education by Dr. V K Sharma'(2018,ISBN:978-93-5272-134-4).
Univariate time series forecasting with STL decomposition based Extreme Learning Machine hybrid model. For method details see Xiong T, Li C, Bao Y (2018). <doi:10.1016/j.neucom.2017.11.053>.
This package implements statistical methods for detecting evolutionary shifts in both the optimal trait value (mean) and evolutionary diffusion variance. The method uses an L1-penalized optimization framework to identify branches where shifts occur, and the shift magnitudes. It also supports the inclusion of measurement error. For more details, see Zhang, Ho, and Kenney (2023) <doi:10.48550/arXiv.2312.17480>.
Efficient procedures for fitting and cross-validating the structurally-regularized time-dependent Cox models.
Population genetics package for designing diagnostic panels. Candidate markers, marker combinations, and different panel sizes are assessed for how well they can predict the source population of known samples. Requires a genotype file of candidate markers in STRUCTURE format. Methods for population cross-validation are described in Jombart (2008) <doi:10.1093/bioinformatics/btn129>.
Manage package documentation and namespaces from the command line. Programmatically attach namespaces in R and Rmd script, populates Roxygen2 skeletons with information scraped from within functions and populate the Imports field of the DESCRIPTION file.
Split Knockoff is a data adaptive variable selection framework for controlling the (directional) false discovery rate (FDR) in structural sparsity, where variable selection on linear transformation of parameters is of concern. This proposed scheme relaxes the linear subspace constraint to its neighborhood, often known as variable splitting in optimization. Simulation experiments can be reproduced following the Vignette. Split Knockoffs is first defined in Cao et al. (2021) <doi:10.48550/arXiv.2103.16159>.
This package provides predictive accuracy tools to evaluate time-to-event survival models. This includes calculating the concordance probability estimate that incorporates the follow-up time for a particular study developed by Devlin, Gonen, Heller (2020)<doi:10.1007/s10985-020-09503-3>. It also evaluates the concordance probability estimate for nested Cox proportional hazards models using a projection-based approach by Heller and Devlin (under review).
This package provides a set of methods to implement Generalized Method of Moments and Maximal Likelihood methods for Random Utility Models. These methods are meant to provide inference on rank comparison data. These methods accept full, partial, and pairwise rankings, and provides methods to break down full or partial rankings into their pairwise components. Please see Generalized Method-of-Moments for Rank Aggregation from NIPS 2013 for a description of some of our methods.
An R Shiny application dedicated to the intra-site spatial analysis of piece-plotted archaeological remains, making the two and three-dimensional spatial exploration of archaeological data as user-friendly as possible. Documentation about SEAHORS is provided by the vignette included in this package and by the companion scientific paper: Royer, Discamps, Plutniak, Thomas (2023, PCI Archaeology, <doi:10.5281/zenodo.7674698>).
This package provides methods for decomposing seasonal data: STR (a Seasonal-Trend time series decomposition procedure based on Regression) and Robust STR. In some ways, STR is similar to Ridge Regression and Robust STR can be related to LASSO. They allow for multiple seasonal components, multiple linear covariates with constant, flexible and seasonal influence. Seasonal patterns (for both seasonal components and seasonal covariates) can be fractional and flexible over time; moreover they can be either strictly periodic or have a more complex topology. The methods provide confidence intervals for the estimated components. The methods can also be used for forecasting.