This package implements core utilities for single-cell RNA-seq data analysis. Contained within are utility functions for working with DE matrices and count matrices, a collection of functions for manipulating and plotting data via ggplot2, and functions to work with cell graphs and cell embeddings. Graph-based methods include embedding kNN cell graphs into a UMAP, collapsing vertices of each cluster in the graph, and propagating graph labels.

This package implements a DBI compliant interface to Presto, a distributed SQL query engine for running interactive analytic queries against data sources of all sizes ranging from gigabytes to petabytes.

This package provides classes and methods for dense and sparse matrices and operations on them using LAPACK and SuiteSparse.

This package implements an S3 class for storing and formatting time-of-day values, based on the difftime class.

This package supplies tools for tabulating and analyzing the results of predictive models. The methods employed are applicable to virtually any predictive model and make comparisons between different methodologies straightforward.

This package facilitates easy manipulation of variant call format (VCF) data. Functions are provided to rapidly read from and write to VCF files. Once VCF data is read into R, a parser function extracts matrices of data. This information can then be used for quality control or other purposes. Additional functions provide visualization of genomic data. Once processing is complete data may be written to a VCF file. It also may be converted into other popular R objects. This package provides a link between VCF data and familiar R software.

R-tgb provides Bayesian nonstationary regression and treed Gaussian processes. In addition, it provides visualization functions, tree drawing, sensitivity analysis, multi-resolution models, and sequential experimental design tools, including ALM, ALC, and expected improvement for optimizing noisy black-box functions.

This is a QTL mapping toolkit for inbred crosses and recombinant inbred lines. It includes maximum likelihood and Bayesian tools.

This package provides functions for animations in statistics, covering topics in probability theory, mathematical statistics, multivariate statistics, non-parametric statistics, sampling survey, linear models, time series, computational statistics, data mining and machine learning. These functions may be helpful in teaching statistics and data analysis. Also provided in this package are a series of functions to save animations to various formats, e.g. GIF, HTML pages, PDF, and videos. PDF animations can be inserted into Sweave / knitr easily.

This package provides tools for capturing logic in a Shiny app and exposing it as code that can be run outside of Shiny (e.g., from an R console). It also provides tools for bundling both the code and results to the end user.

This package fits models for genotypic disequilibria, as described in Huttley and Wilson (2000), Weir (1996) and Weir and Wilson (1986). Contrast terms are available that account for first order interactions between loci. It also implements, for a single locus in a single population, a conditional exact test for Hardy-Weinberg equilibrium.

This package provides functions for obtaining the density, random variates and maximum likelihood estimates of the Zero-truncated Poisson lognormal distribution and their mixture distribution.

This package contains three main functions including stddiff.numeric(), stddiff.binary() and stddiff.category(). These are used to calculate the standardized difference between two groups. It is especially used to evaluate the balance between two groups before and after propensity score matching.

This package provides R bindings for Google's s2 library for geometric calculations on the sphere. High-performance constructors and exporters provide high compatibility with existing spatial packages, transformers construct new geometries from existing geometries, predicates provide a means to select geometries based on spatial relationships, and accessors extract information about geometries.

This package provides functions for extracting feature contributions from a random forest model from package randomForest. Feature contributions provide detailed information about the relationship between data variables and the predicted value returned by random forest model.

This package provides a set of tools to permute multisets without loops or hash tables and to generate integer partitions. Cool-lex order is similar to colexicographical order.

This package implements multiple imputation for multivariate panel or clustered data.

This package allows estimation and modelling of flight costs in animal (vertebrate) flight, implementing the aerodynamic power model. Flight performance is estimated based on basic morphological measurements such as body mass, wingspan and wing area. Afpt can be used to make predictions on how animals should adjust their flight behaviour and wingbeat kinematics to varying flight conditions.

This package provides a system for querying, retrieving and analyzing protocol- and results-related information on clinical trials from three public registers, the European Union Clinical Trials Register (EUCTR), ClinicalTrials.gov (CTGOV) and the ISRCTN. Trial information is downloaded, converted and stored in a database. Functions are included to identify deduplicated records, to easily find and extract variables (fields) of interest even from complex nesting as used by the registers, and to update previous queries. The package can be used for meta-analysis and trend-analysis of the design and conduct as well as for results of clinical trials.

This package provides a set of tools to help explain which variables are most important in a random forests. Various variable importance measures are calculated and visualized in different settings in order to get an idea on how their importance changes depending on our criteria (Hemant Ishwaran and Udaya B. Kogalur and Eiran Z. Gorodeski and Andy J. Minn and Michael S. Lauer (2010) <doi:10.1198/jasa.2009.tm08622>, Leo Breiman (2001) <doi:10.1023/A:1010933404324>).

This package provides a micro-package for reading "passwords", i.e. reading user input with masking, so that the input is not displayed as it is typed. Currently, RStudio, the command line (every OS), and any platform where tcltk is present are supported.

For tree ensembles such as random forests, regularized random forests and gradient boosted trees, this package provides functions for: extracting, measuring and pruning rules; selecting a compact rule set; summarizing rules into a learner; calculating frequent variable interactions; formatting rules in latex code. Reference: Interpreting tree ensembles with inTrees (Houtao Deng, 2019, <doi:10.1007/s41060-018-0144-8>).

This package provides a set of predicates and assertions for checking the properties of code. This is mainly for use by other package developers who want to include run-time testing features in their own packages.

This package provides miscellaneous functions for training and plotting classification and regression models.