An interval-valued extension of ordinary and simple kriging. Optimization of the function is based on a generalized interval distance. This creates a non-differentiable cost function that requires a differentiable approximation to the absolute value function. This differentiable approximation is optimized using a Newton-Raphson algorithm with a penalty function to impose the constraints. Analyses in the package are driven by the intsp and intgrd classes, which are interval-valued extensions of SpatialPointsDataFrame and SpatialPixelsDataFrame respectively. The package includes several wrappers to functions in the gstat and sp packages.

This package contains some important regression methods for interval-valued variables. For each method, it is available the fitted values, residuals and some goodness-of-fit measures.

The development of ISM was made by Warfield in 1974. ISM is the process of collaborating distinct or related essentials into a simplified and an organized format. Hence, ISM is a methodology that seeks the interrelationships among the various elements considered and endows with a hierarchical and multilevel structure. To run this package user needs to provide a matrix (VAXO) converted into 0's and 1's. Warfield,J.N. (1974) <doi:10.1109/TSMC.1974.5408524> Warfield,J.N. (1974, E-ISSN:2168-2909).

Multiple Imputation for Informative Censoring. This package implements two methods. Gamma Imputation described in <DOI:10.1002/sim.6274> and Risk Score Imputation described in <DOI:10.1002/sim.3480>.

This package provides a collection of statistical tests for genetic association studies and summary data based Mendelian randomization.

This package performs hypothesis testing using the interval estimates (e.g., confidence intervals). The non-overlapping interval estimates indicates the statistical significance. References to these procedures can be found at Noguchi and Marmolejo-Ramos (2016) <doi:10.1080/00031305.2016.1200487>, Bonett and Seier (2003) <doi:10.1198/0003130032323>, and Lemm (2006) <doi:10.1300/J082v51n02_05>.

This package provides a bunch of functions to deal with circular data under order restrictions.

We provide an R tool for teaching in Social Sciences. It allows the computation of index numbers. It is a measure of the evolution of a fixed magnitude for only a product of for several products. It is very useful in Social Sciences. Among others, we obtain simple index numbers (in chain or in serie), index numbers for not only a product or weighted index numbers as the Laspeyres index (Laspeyres, 1864), the Paasche index (Paasche, 1874) or the Fisher index (Lapedes, 1978).

Identify Cancer Dysfunctional Sub-pathway by integrating gene expression, DNA methylation and copy number variation, and pathway topological information. 1)We firstly calculate the gene risk scores by integrating three kinds of data: DNA methylation, copy number variation, and gene expression. 2)Secondly, we perform a greedy search algorithm to identify the key dysfunctional sub-pathways within the pathways for which the discriminative scores were locally maximal. 3)Finally, the permutation test was used to calculate statistical significance level for these key dysfunctional sub-pathways.

Read and process isotopocule data from an Orbitrap Isotope Solutions mass spectrometer. Citation: Kantnerova et al. (Nature Protocols, 2024).

This package provides color palettes from Impressionism and post-Impressionism artworks. This package allows to select colors combinations while looking at the original paintings where colors were sampled from.

This package provides a joint mixture model has been developed by Majumdar et al. (2025) <doi:10.48550/arXiv.2412.17511> that integrates information from gene expression data and methylation data at the modelling stage to capture their inherent dependency structure, enabling simultaneous identification of differentially methylated cytosine-guanine dinucleotide (CpG) sites and differentially expressed genes. The model leverages a joint likelihood function that accounts for the nested structure in the data, with parameter estimation performed using an expectation-maximisation algorithm.

Empirical Bayes variable selection via ICM/M algorithm for normal, binary logistic, and Cox's regression. The basic problem is to fit high-dimensional regression which sparse coefficients. This package allows incorporating the Ising prior to capture structure of predictors in the modeling process. More information can be found in the papers listed in the URL below.

The 14th generation International Geomagnetic Reference Field (IGRF). A standard spherical harmonic representation of the Earth's main field.

This package provides an R interface to Julia', which is a high-level, high-performance dynamic programming language for numerical computing, see <https://julialang.org/> for more information. It provides a high-level interface as well as a low-level interface. Using the high level interface, you could call any Julia function just like any R function with automatic type conversion. Using the low level interface, you could deal with C-level SEXP directly while enjoying the convenience of using a high-level programming language like Julia'.

This package contains a selection of color palettes and ggplot2 themes designed by the package author.

Helpful functions for using mesh code (80km to 100m) data in Japan. Visualize mesh code using ggplot2 and leaflet', etc.

Procedures for joint detection of changes in both expectation and variance in univariate sequences. Performs a statistical test of the null hypothesis of the absence of change points. In case of rejection performs an algorithm for change point detection. Reference - Bivariate change point detection - joint detection of changes in expectation and variance, Scandinavian Journal of Statistics, DOI 10.1111/sjos.12547.

Fit latent space network cluster models using an expectation-maximization algorithm. Enables flexible modeling of unweighted or weighted network data (with or without noise edges), supporting both directed and undirected networks (with or without degree and strength heterogeneity). Designed to handle large networks efficiently, it allows users to explore network structure through latent space representations, identify clusters (i.e., community detection) within network data, and simulate networks with varying clustering, connectivity patterns, and noise edges. Methodology for the implementation is described in Arakkal and Sewell (2025) <doi:10.1016/j.csda.2025.108228>.

This package provides methods to perform Joint graph Regularized Single-Cell Kullback-Leibler Sparse Non-negative Matrix Factorization ('jrSiCKLSNMF', pronounced "junior sickles NMF") on quality controlled single-cell multimodal omics count data. jrSiCKLSNMF specifically deals with dual-assay scRNA-seq and scATAC-seq data. This package contains functions to extract meaningful latent factors that are shared across omics modalities. These factors enable accurate cell-type clustering and facilitate visualizations. Methods for pre-processing, clustering, and mini-batch updates and other adaptations for larger datasets are also included. For further details on the methods used in this package please see Ellis, Roy, and Datta (2023) <doi:10.3389/fgene.2023.1179439>.

This package provides a Joint PENalty Estimation of Covariance and Inverse Covariance Matrices.

This package provides a calculation tool to obtain the 5-year or 10-year risk of cardiovascular disease from various risk models.

Uses the Jaccard similarity index to account for population structure in sequencing studies. This method was specifically designed to detect population stratification based on rare variants, hence it will be especially useful in rare variant analysis.

This package provides a suite of common statistical methods such as descriptives, t-tests, ANOVAs, regression, correlation matrices, proportion tests, contingency tables, and factor analysis. This package is also useable from the jamovi statistical spreadsheet (see <https://www.jamovi.org> for more information).