Created for population health analytics and monitoring. The functions in this package work best when working with patient level Master Patient Index-like datasets . Built to be used by NHS bodies and other health service providers.

Download data (tables and datasets) from the Swiss National Bank (SNB; <https://www.snb.ch/en>), the Swiss central bank. The package is lightweight and comes with few dependencies; suggested packages are used only if data is to be transformed into particular data structures, for instance into zoo objects. Downloaded data can optionally be cached, to avoid repeated downloads of the same files.

This package provides functions for fitting discrete distribution models to count data. Included are the Poisson, the negative binomial, the Poisson-inverse gaussian and, most importantly, a new implementation of the Poisson-beta distribution (density, distribution and quantile functions, and random number generator) together with a needed new implementation of Kummer's function (also: confluent hypergeometric function of the first kind). Three different implementations of the Gillespie algorithm allow data simulation based on the basic, switching or bursting mRNA generating processes. Moreover, likelihood functions for four variants of each of the three aforementioned distributions are also available. The variants include one population and two population mixtures, both with and without zero-inflation. The package depends on the MPFR libraries (<https://www.mpfr.org/>) which need to be installed separately (see description at <https://github.com/fuchslab/scModels>). This package is supplement to the paper "A mechanistic model for the negative binomial distribution of single-cell mRNA counts" by Lisa Amrhein, Kumar Harsha and Christiane Fuchs (2019) <doi:10.1101/657619> available on bioRxiv.

Execute files of SQL and manage database connections. SQL statements and queries may be interpolated with string literals. Execution of individual statements and queries may be controlled with keywords. Multiple connections may be defined with YAML and accessed by name.

Finite element modeling (FEM) uses meshes of triangles to define surfaces. A surface within a triangle may be either linear or quadratic. In the order one case each node in the mesh is associated with a basis function and the basis is called the order one finite element basis. In the order two case each edge mid-point is also associated with a basis function. Functions are provided for smoothing, density function estimation point evaluation and plotting results. Two papers illustrating the finite element data analysis are Sangalli, L.M., Ramsay, J.O., Ramsay, T.O. (2013)<http://www.mox.polimi.it/~sangalli> and Bernardi, M.S, Carey, M., Ramsay, J. O., Sangalli, L. (2018)<http://www.mox.polimi.it/~sangalli>. Modelling spatial anisotropy via regression with partial differential regularization Journal of Multivariate Analysis, 167, 15-30.

This package implements a generative model that uses a spike-and-slab like prior distribution obtained by multiplying a deterministic binary vector. Such a model allows an EM algorithm, optimizing a type-II log-likelihood.

Fits single-species, multi-species, and integrated non-spatial and spatial occupancy models using Markov Chain Monte Carlo (MCMC). Models are fit using Polya-Gamma data augmentation detailed in Polson, Scott, and Windle (2013) <doi:10.1080/01621459.2013.829001>. Spatial models are fit using either Gaussian processes or Nearest Neighbor Gaussian Processes (NNGP) for large spatial datasets. Details on NNGP models are given in Datta, Banerjee, Finley, and Gelfand (2016) <doi:10.1080/01621459.2015.1044091> and Finley, Datta, and Banerjee (2022) <doi:10.18637/jss.v103.i05>. Provides functionality for data integration of multiple single-species occupancy data sets using a joint likelihood framework. Details on data integration are given in Miller, Pacifici, Sanderlin, and Reich (2019) <doi:10.1111/2041-210X.13110>. Details on single-species and multi-species models are found in MacKenzie, Nichols, Lachman, Droege, Royle, and Langtimm (2002) <doi:10.1890/0012-9658(2002)083[2248:ESORWD]2.0.CO;2> and Dorazio and Royle <doi:10.1198/016214505000000015>, respectively.

Sample size and effect size calculations for survival endpoints based on mixture survival-by-response model. The methods implemented can be found in Bofill, Shen & Gómez (2021) <arXiv:2008.12887>.

Estimate the parameters of multivariate endogenous switching and sample selection models using methods described in Newey (2009) <doi:10.1111/j.1368-423X.2008.00263.x>, E. Kossova, B. Potanin (2018) <https://ideas.repec.org/a/ris/apltrx/0346.html>, E. Kossova, L. Kupriianova, B. Potanin (2020) <https://ideas.repec.org/a/ris/apltrx/0391.html> and E. Kossova, B. Potanin (2022) <https://ideas.repec.org/a/ris/apltrx/0455.html>.

Download data from StatsWales into R. Removes the need for the user to write their own loops when parsing data from the StatsWales API. Provides functions for datasets (<http://open.statswales.gov.wales/en-gb/dataset>) and metadata (<http://open.statswales.gov.wales/en-gb/discover/metadata>) endpoints.

This package provides a simple progress bar to use for basic and advanced users that suits all those who prefer procedural programming. It is especially useful for integration into markdown files thanks to the progress bar's customisable appearance.

Complex machine learning models are often hard to interpret. However, in many situations it is crucial to understand and explain why a model made a specific prediction. Shapley values is the only method for such prediction explanation framework with a solid theoretical foundation. Previously known methods for estimating the Shapley values do, however, assume feature independence. This package implements methods which accounts for any feature dependence, and thereby produces more accurate estimates of the true Shapley values. An accompanying Python wrapper ('shaprpy') is available through the GitHub repository.

Efficient Markov chain Monte Carlo (MCMC) algorithms for fully Bayesian estimation of time-varying parameter vector autoregressive models with stochastic volatility (TVP-VAR-SV) under shrinkage priors and dynamic shrinkage processes. Details on the TVP-VAR-SV model and the shrinkage priors can be found in Cadonna et al. (2020) <doi:10.3390/econometrics8020020>, details on the software can be found in Knaus et al. (2021) <doi:10.18637/jss.v100.i13>, while details on the dynamic shrinkage process can be found in Knaus and Frühwirth-Schnatter (2023) <doi:10.48550/arXiv.2312.10487>.

This package provides a comprehensive Shiny application for analyzing Whole Genome Duplication ('WGD') events. This package provides a user-friendly Shiny web application for non-experienced researchers to prepare input data and execute command lines for several well-known WGD analysis tools, including wgd', ksrates', i-ADHoRe', OrthoFinder', and Whale'. This package also provides the source code for experienced researchers to adjust and install the package to their own server. Key Features 1) Input Data Preparation This package allows users to conveniently upload and format their data, making it compatible with various WGD analysis tools. 2) Command Line Generation This package automatically generates the necessary command lines for selected WGD analysis tools, reducing manual errors and saving time. 3) Visualization This package offers interactive visualizations to explore and interpret WGD results, facilitating in-depth WGD analysis. 4) Comparative Genomics Users can study and compare WGD events across different species, aiding in evolutionary and comparative genomics studies. 5) User-Friendly Interface This Shiny web application provides an intuitive and accessible interface, making WGD analysis accessible to researchers and bioinformaticians of all levels.

Fit latent variable models with the GEV distribution as the data likelihood and the GEV parameters following latent Gaussian processes. The models in this package are built using the template model builder TMB in R, which has the fast ability to integrate out the latent variables using Laplace approximation. This package allows the users to choose in the fit function which GEV parameter(s) is considered as a spatially varying random effect following a Gaussian process, so the users can fit spatial GEV models with different complexities to their dataset without having to write the models in TMB by themselves. This package also offers methods to sample from both fixed and random effects posteriors as well as the posterior predictive distributions at different spatial locations. Methods for fitting this class of models are described in Chen, Ramezan, and Lysy (2024) <doi:10.48550/arXiv.2110.07051>.

This package provides a set of functions to build a scoring model from beginning to end, leading the user to follow an efficient and organized development process, reducing significantly the time spent on data exploration, variable selection, feature engineering, binning and model selection among other recurrent tasks. The package also incorporates monotonic and customized binning, scaling capabilities that transforms logistic coefficients into points for a better business understanding and calculates and visualizes classic performance metrics of a classification model.

Test and estimates of location, tests of independence, tests of sphericity and several estimates of shape all based on spatial signs, symmetrized signs, ranks and signed ranks. For details, see Oja and Randles (2004) <doi:10.1214/088342304000000558> and Oja (2010) <doi:10.1007/978-1-4419-0468-3>.

This package provides a Bayesian semiparametric Dirichlet process mixtures to estimate correlated receiver operating characteristic (ROC) surfaces and the associated volume under the surface (VUS) with stochastic order constraints. The reference paper is:Zhen Chen, Beom Seuk Hwang, (2018) "A Bayesian semiparametric approach to correlated ROC surfaces with stochastic order constraints". Biometrics, 75, 539-550. <doi:10.1111/biom.12997>.

Inspired by the art and color research of Sanzo Wada (1883-1967), his "Dictionary Of Color Combinations" (2011, ISBN:978-4861522475), and the interactive site by Dain M. Blodorn Kim <https://github.com/dblodorn/sanzo-wada>, this package brings Wada's color combinations to R for easy use in data visualizations. This package honors 60 of Wada's color combinations: 20 duos, 20 trios, and 20 quads.

This package contains methods to generate and evaluate semi-artificial data sets. Based on a given data set different methods learn data properties using machine learning algorithms and generate new data with the same properties. The package currently includes the following data generators: i) a RBF network based generator using rbfDDA() from package RSNNS', ii) a Random Forest based generator for both classification and regression problems iii) a density forest based generator for unsupervised data Data evaluation support tools include: a) single attribute based statistical evaluation: mean, median, standard deviation, skewness, kurtosis, medcouple, L/RMC, KS test, Hellinger distance b) evaluation based on clustering using Adjusted Rand Index (ARI) and FM c) evaluation based on classification performance with various learning models, e.g., random forests.

This package provides a sparklyr extension package providing an integration with Google BigQuery'. It supports direct import/export where records are directly streamed from/to BigQuery'. In addition, data may be imported/exported via intermediate data extracts on Google Cloud Storage'.

An English language syllable counter, plus readability score measure-er. For readability, we support Flesch Reading Ease and Flesch-Kincaid Grade Level ('Kincaid et al'. 1975) <https://stars.library.ucf.edu/cgi/viewcontent.cgi?article=1055&context=istlibrary>, Automated Readability Index ('Senter and Smith 1967) <https://apps.dtic.mil/sti/citations/AD0667273>, Simple Measure of Gobbledygook (McLaughlin 1969), and Coleman-Liau (Coleman and Liau 1975) <doi:10.1037/h0076540>. The package has been carefully optimized and should be very efficient, both in terms of run time performance and memory consumption. The main methods are vectorized by document, and scores for multiple documents are computed in parallel via OpenMP'.

An overall test for seasonality of a given time series in addition to a set of individual seasonality tests as described by Ollech and Webel (forthcoming): An overall seasonality test. Bundesbank Discussion Paper.

This package provides the necessary sample size for a longitudinal study with binary outcome in order to attain a pre-specified power while strictly maintaining the Type I error rate. Kapur K, Bhaumik R, Tang XC, Hur K, Reda DJ, Bhaumik D (2014) <doi:10.1002/sim.6203>.