Set of functions that implement the PoDBAY method, described in the publication A method to estimate probability of disease and vaccine efficacy from clinical trial immunogenicity data by Julie Dudasova, Regina Laube, Chandni Valiathan, Matthew C. Wiener, Ferdous Gheyas, Pavel Fiser, Justina Ivanauskaite, Frank Liu and Jeffrey R. Sachs (NPJ Vaccines, 2021), <doi:10.1038/s41541-021-00377-6>.

Visualizes the coverage depth of a complete plastid genome as well as the equality of its inverted repeat regions in relation to the circular, quadripartite genome structure and the location of individual genes. For more information, please see Gruenstaeudl and Jenke (2020) <doi:10.1186/s12859-020-3475-0>.

The first goal of this package is to provide a multitude of tree models, i.e., functions that generate rooted binary trees with a given number of leaves. Second, the package allows for an easy evaluation and comparison of tree shape statistics by estimating their power to differentiate between different tree models. Please note that this R package was developed alongside the manuscript Tree balance in phylogenetic models by S. J. Kersting, K. Wicke, and M. Fischer (2025) <doi:10.1098/rstb.2023.0303>, which provides further background and the respective mathematical definitions. This project was supported by the project ArtIGROW, which is a part of the WIR!-Alliance ArtIFARM â Artificial Intelligence in Farming funded by the German Federal Ministry of Education and Research (No. 03WIR4805).

This package provides a set of functions for reading and writing PC-Axis files, used by different statistical organizations around the globe for data dissemination.

Power and sample size calculation for bulk tissue and single-cell eQTL analysis based on ANOVA, simple linear regression, or linear mixed effects model. It can also calculate power/sample size for testing the association of a SNP to a continuous type phenotype. Please see the reference: Dong X, Li X, Chang T-W, Scherzer CR, Weiss ST, Qiu W. (2021) <doi:10.1093/bioinformatics/btab385>.

This package provides tools from the domain of graph theory can be used to quantify the complexity and vulnerability to failure of a software package. That is the guiding philosophy of this package. pkgnet provides tools to analyze the dependencies between functions in an R package and between its imported packages. See the pkgnet website for vignettes and other supplementary information.

This package implements Penalized Fast Causal Inference (PFCI), a two-stage causal structure learning procedure for high-dimensional settings with potential latent variables and selection bias. In the first stage, neighborhood selection via the Lasso constructs a sparse undirected skeleton. In the second stage, the Fast Causal Inference (FCI) algorithm orients edges on this reduced graph, producing a Partial Ancestral Graph (PAG) that accounts for latent confounders. The method is consistent under sparsity assumptions and substantially faster than standard FCI and RFCI in high dimensions. See Pal, Ghosh, and Yang (2025) <doi:10.48550/arXiv.2507.00173> for the underlying theory.

Makes output files from select PreSens Fiber Optic Oxygen Transmitters easier to work with in R. See <http://www.presens.de> for more information about PreSens (Precision Sensing GmbH). Note: this package is neither created nor maintained by PreSens.

Perform flexible and quick calculations for Demand and Supply Planning, such as projected inventories and coverages, as well as replenishment plan. For any time bucket, daily, weekly or monthly, and any granularity level, product or group of products.

Puzzle game that can be played in the R console. Restore the pixel art by shifting rows.

This package provides a user interface to create or modify pharmacometric models for various modeling and simulation software platforms.

Analysis and measurement of promotion effectiveness on a given target variable (e.g. daily sales). After converting promotion schedule into dummy or smoothed predictor variables, the package estimates the effects of these variables controlled for trend/periodicity/structural change using prophet by Taylor and Letham (2017) <doi:10.7287/peerj.preprints.3190v2> and some prespecified variables (e.g. start of a month).

partitionMetric computes a distance between two partitions of a set.

Allows specification and fitting of some parameter estimation examples inspired by time-resolved spectroscopy via a Shiny GUI.

Proteins reside in either the cell plasma or in the cell membrane. A membrane protein goes through the membrane at least once. Given the amino acid sequence of a membrane protein, the tool PureseqTM (<https://github.com/PureseqTM/pureseqTM_package>, as described in "Efficient And Accurate Prediction Of Transmembrane Topology From Amino acid sequence only.", Wang, Qing, et al (2019), <doi:10.1101/627307>), can predict the topology of a membrane protein. This package allows one to use PureseqTM from R.

Normalization of numerical matrices by minimizing the mean/median/mode difference between all column pairs.

Check a data frame for personal information, including names, location, disability status, and geo-coordinates.

Calculate and optimize dynamic performance ratings of association football teams competing in matches, in accordance with the method used in the research paper "Determining the level of ability of football teams by dynamic ratings based on the relative discrepancies in scores between adversaries", by Constantinou and Fenton (2013) <doi:10.1515/jqas-2012-0036> This dynamic rating system has proven to provide superior results for predicting association football outcomes.

Translating messages in R packages is managed using the po top-level directory and the gettext program. This package provides some helper functions for building this support in R packages, e.g. common validation & I/O tasks.

Smoothing splines with penalties on order m derivatives.

Automatically create a web server from annotated R files or by building it up programmatically. Provides automatic OpenAPI documentation, input handling, asynchronous evaluation, and plugin support.

Translates beliefs into prior information in the form of Beta and Gamma distributions. It can be used for the generation of priors on the prevalence of disease and the sensitivity/specificity of diagnostic tests and any other binomial experiment.

This package provides a comprehensive and curated collection of datasets related to the lungs, respiratory system, and associated diseases. This package includes epidemiological, clinical, experimental, and simulated datasets on conditions such as lung cancer, asthma, Chronic Obstructive Pulmonary Disease (COPD), tuberculosis, whooping cough, pneumonia, influenza, and other respiratory illnesses. It is designed to support data exploration, statistical modeling, teaching, and research in pulmonary medicine, public health, environmental epidemiology, and respiratory disease surveillance.

Statistical methods for estimating preferential attachment and node fitness generative mechanisms in temporal complex networks are provided. Thong Pham et al. (2015) <doi:10.1371/journal.pone.0137796>. Thong Pham et al. (2016) <doi:10.1038/srep32558>. Thong Pham et al. (2020) <doi:10.18637/jss.v092.i03>. Thong Pham et al. (2021) <doi:10.1093/comnet/cnab024>.