Estimation of two-state (survival) models and irreversible illness- death models with possibly interval-censored, left-truncated and right-censored data. Proportional intensities regression models can be specified to allow for covariates effects separately for each transition. We use either a parametric approach with Weibull baseline intensities or a semi-parametric approach with M-splines approximation of baseline intensities in order to obtain smooth estimates of the hazard functions. Parameter estimates are obtained by maximum likelihood in the parametric approach and by penalized maximum likelihood in the semi-parametric approach.

This package contains functions for statistical data analysis based on spatially-clustered techniques. The package allows estimating the spatially-clustered spatial regression models presented in Cerqueti, Maranzano \& Mattera (2024), "Spatially-clustered spatial autoregressive models with application to agricultural market concentration in Europe", arXiv preprint 2407.15874 <doi:10.48550/arXiv.2407.15874>. Specifically, the current release allows the estimation of the spatially-clustered linear regression model (SCLM), the spatially-clustered spatial autoregressive model (SCSAR), the spatially-clustered spatial Durbin model (SCSEM), and the spatially-clustered linear regression model with spatially-lagged exogenous covariates (SCSLX). From release 0.0.2, the library contains functions to estimate spatial clustering based on Adiajacent Matrix K-Means (AMKM) as described in Zhou, Liu \& Zhu (2019), "Weighted adjacent matrix for K-means clustering", Multimedia Tools and Applications, 78 (23) <doi:10.1007/s11042-019-08009-x>.

This package provides tools for Bayesian learning of spatiotemporal dynamical mechanistic models. Includes methods for parameter estimation, simulation, and inference using hierarchical and state-space modeling approaches, following Banerjee, Chen, Frankenburg and Zhou (2025) <https://jmlr.org/papers/v26/22-0896.html>.

Create mocked bindings to Shiny update functions within test function calls to automatically update input values. The mocked bindings simulate the communication between the server and UI components of a Shiny module in testServer().

This package provides functions that provide statistical methods for interval-censored (grouped) data. The package supports the estimation of linear and linear mixed regression models with interval-censored dependent variables. Parameter estimates are obtained by a stochastic expectation maximization algorithm. Furthermore, the package enables the direct (without covariates) estimation of statistical indicators from interval-censored data via an iterative kernel density algorithm. Survey and Organisation for Economic Co-operation and Development (OECD) weights can be included into the direct estimation (see, Walter, P. (2019) <doi:10.17169/refubium-1621>).

Remove batch effects by projecting query batches into the reference batch space.

Offers a suite of functions for converting to and from (atomic) vectors, matrices, data.frames, and (3D+) arrays as well as lists of these objects. It is an alternative to the base R as.<str>.<method>() functions (e.g., as.data.frame.array()) that provides more useful and/or flexible restructuring of R objects. To do so, it only works with common structuring of R objects (e.g., data.frames with only atomic vector columns).

Generate common data forms for complex data suitable for conversions and transmission by decomposition as paths or primitives. Paths are sequentially-linked records, primitives are basic atomic elements and both can model many forms and be grouped into hierarchical structures. The universal models SC0 (structural) and SC (labelled, relational) are composed of edges and can represent any hierarchical form. Specialist models PATH', ARC and TRI provide the most common intermediate forms used for converting from one form to another. The methods are inspired by the simplicial complex <https://en.wikipedia.org/wiki/Simplicial_complex> and provide intermediate forms that relate spatial data structures to this mathematical construct.

Supports simulating choice experiment data for given designs. It helps to quickly test different designs against each other and compare the performance of new models. The goal of simulateDCE is to make it easy to simulate choice experiment datasets using designs from NGENE', idefix or spdesign'. You have to store the design file(s) in a sub-directory and need to specify certain parameters and the utility functions for the data generating process. For more details on choice experiments see Mariel et al. (2021) <doi:10.1007/978-3-030-62669-3>.

Fits symmetric soft windowing to linear and non-linear models by assigning exponential weights over time around specified modes; bandwidth and sharpness of the windows are chosen by a grid search and comparison diagnostics (Hamed Haselimashhadi et al (2019) <doi:10.1093/bioinformatics/btz744>).

For Multi Parent Populations (MPP) Identity By Descend (IBD) probabilities are computed using Hidden Markov Models. These probabilities are then used in a mixed model approach for QTL Mapping as described in Li et al. (<doi:10.1007/s00122-021-03919-7>).

Fits singular linear models to longitudinal data. Singular linear models are useful when the number, or timing, of longitudinal observations may be informative about the observations themselves. They are described in Farewell (2010) <doi:10.1093/biomet/asp068>, and are extensions of the linear increments model <doi:10.1111/j.1467-9876.2007.00590.x> to general longitudinal data.

This package provides a toolbox for constructing potential landscapes for dynamical systems using Monte Carlo simulation. The method is based on the potential landscape definition by Wang et al. (2008) <doi:10.1073/pnas.0800579105> (also see Zhou & Li, 2016 <doi:10.1063/1.4943096> for further mathematical discussions) and can be used for a large variety of models.

SEM Trees and SEM Forests -- an extension of model-based decision trees and forests to Structural Equation Models (SEM). SEM trees hierarchically split empirical data into homogeneous groups each sharing similar data patterns with respect to a SEM by recursively selecting optimal predictors of these differences. SEM forests are an extension of SEM trees. They are ensembles of SEM trees each built on a random sample of the original data. By aggregating over a forest, we obtain measures of variable importance that are more robust than measures from single trees. A description of the method was published by Brandmaier, von Oertzen, McArdle, & Lindenberger (2013) <doi:10.1037/a0030001> and Arnold, Voelkle, & Brandmaier (2020) <doi:10.3389/fpsyg.2020.564403>.

Used to construct the URLs and parameters of Socrata Open Data API <https://dev.socrata.com> calls, using the API's SoQL parameter format. Has method-chained and sensical syntax. Plays well with pipes.

This package provides a fast implementation of the SWAG algorithm for Generalized Linear Models which allows to perform a meta-learning procedure that combines screening and wrapper methods to find a set of extremely low-dimensional attribute combinations. The package then performs test on the network of selected models to identify the variables that are highly predictive by using entropy-based network measures.

Computes smooth estimations for the Cumulative/Dynamic and Incident/Dynamic ROC curves, in presence of right censorship, based on the bivariate kernel density estimation of the joint distribution function of the Marker and Time-to-event variables.

An API to build and control 2D games using the Phaser JavaScript engine. It enables integration with shiny applications, allowing to create interactive games and simulations.

An user-friendly framework to preprocess raw item scores of questionnaires into factors or scores and standardize them. Standardization can be made either by their normalization in representative sample, or by import of premade scoring table.

This sparklyr extension makes Flint time series library functionalities (<https://github.com/twosigma/flint>) easily accessible through R.

This package provides a suite of helper functions to support Bayesian Kernel Machine Regression (BKMR) analyses in environmental health research. It enables the simulation of realistic multivariate exposure data using Multivariate Skewed Gamma distributions, estimation of distributional parameters by subgroup, and application of adaptive, data-driven thresholds for feature selection via Posterior Inclusion Probabilities (PIPs). It is especially suited for handling skewed exposure data and enhancing the interpretability of BKMR results through principled variable selection. The methodology is shown in Hasan et. al. (2025) <doi:10.1101/2025.04.14.25325822>.

Powerful graphical displays and statistical tools for structured problem solving and diagnosis. The functions of the sherlock package are especially useful for applying the process of elimination as a problem diagnosis technique. The sherlock package was designed to seamlessly work with the tidyverse set of packages and provides a collection of graphical displays built on top of the ggplot and plotly packages, such as different kinds of small multiple plots as well as helper functions such as adding reference lines, normalizing observations, reading in data or saving analysis results in an Excel file. References: David Hartshorne (2019, ISBN: 978-1-5272-5139-7). Stefan H. Steiner, R. Jock MacKay (2005, ISBN: 0873896467).

Computes the extended spring indices (SI-x) and false spring exposure indices (FSEI). The SI-x indices are standard indices used for analysis in spring phenology studies. In addition, the FSEI is also from research on the climatology of false springs and adjusted to include an early and late false spring exposure index. The indices include the first leaf index, first bloom index, and false spring exposure indices, along with all calculations for all functions needed to calculate each index. The main function returns all indices, but each function can also be run separately. Allstadt et al. (2015) <doi: 10.1088/1748-9326/10/10/104008> Ault et al. (2015) <doi: 10.1016/j.cageo.2015.06.015> Peterson and Abatzoglou (2014) <doi: 10.1002/2014GL059266> Schwarz et al. (2006) <doi: 10.1111/j.1365-2486.2005.01097.x> Schwarz et al. (2013) <doi: 10.1002/joc.3625>.

Generates and predicts a set of linearly stacked Random Forest models using bootstrap sampling. Individual datasets may be heterogeneous (not all samples have full sets of features). Contains support for parallelization but the user should register their cores before running. This is an extension of the method found in Matlock (2018) <doi:10.1186/s12859-018-2060-2>.