This package provides functions to implement group sequential procedures that allow for early stopping to declare efficacy using a surrogate marker and the possibility of futility stopping. More details are available in: Parast, L. and Bartroff, J (2024) <doi:10.1093/biomtc/ujae108>. A tutorial for this package can be found at <https://laylaparast.com/home/SurrogateSeq.html>.

This package provides a flexible tool for simulating complex longitudinal data using structural equations, with emphasis on problems in causal inference. Specify interventions and simulate from intervened data generating distributions. Define and evaluate treatment-specific means, the average treatment effects and coefficients from working marginal structural models. User interface designed to facilitate the conduct of transparent and reproducible simulation studies, and allows concise expression of complex functional dependencies for a large number of time-varying nodes. See the package vignette for more information, documentation and examples.

Simulate multivariate correlated data given nonparametric marginals and their joint structure characterized by a Pearson or Spearman correlation matrix. The simulator engages the problem from a purely computational perspective. It assumes no statistical models such as copulas or parametric distributions, and can approximate the target correlations regardless of theoretical feasibility. The algorithm integrates and advances the Iman-Conover (1982) approach <doi:10.1080/03610918208812265> and the Ruscio-Kaczetow iteration (2008) <doi:10.1080/00273170802285693>. Package functions are carefully implemented in C++ for squeezing computing speed, suitable for large input in a manycore environment. Precision of the approximation and computing speed both substantially outperform various CRAN packages to date. Benchmarks are detailed in function examples. A simple heuristic algorithm is additionally designed to optimize the joint distribution in the post-simulation stage. The heuristic demonstrated good potential of achieving the same level of precision of approximation without the enhanced Iman-Conover-Ruscio-Kaczetow. The package contains a copy of Permuted Congruential Generator.

This package provides a group of functions to scrape data from different websites, for academic purposes.

Allow sharing sensitive information, for example passwords, API keys, etc., in R packages, using public key cryptography.

This package provides functionality for simulating data generation processes across various spatial regression models, conceptually aligned with the dgp module of the Python library spreg <https://pysal.org/spreg/api.html#dgp>.

It offers functions for creating dashboard with Fomantic UI.

Machine learning provides algorithms that can learn from data and make inferences or predictions. Stochastic automata is a class of input/output devices which can model components. This work provides implementation an inference algorithm for stochastic automata which is similar to the Viterbi algorithm. Moreover, we specify a learning algorithm using the expectation-maximization technique and provide a more efficient implementation of the Baum-Welch algorithm for stochastic automata. This work is based on Inference and learning in stochastic automata was by Karl-Heinz Zimmermann(2017) <doi:10.12732/ijpam.v115i3.15>.

Computing the one-sided/two-sided integrated/maximally selected EL statistics for simultaneous testing, the one-sided/two-sided EL tests for pointwise testing, and an initial test that precedes one-sided testing to exclude the possibility of crossings or alternative orderings among the survival functions.

Modern classes for tracking and movement data, building on sf spatial infrastructure, and early theoretical work from Turchin (1998, ISBN: 9780878938476), and Calenge et al. (2009) <doi:10.1016/j.ecoinf.2008.10.002>. Tracking data are series of locations with at least 2-dimensional spatial coordinates (x,y), a time index (t), and individual identification (id) of the object being monitored; movement data are made of trajectories, i.e. the line representation of the path, composed by steps (the straight-line segments connecting successive locations). sftrack is designed to handle movement of both living organisms and inanimate objects.

SparseGrid is a package to create sparse grids for numerical integration, based on code from www.sparse-grids.de.

Analysis of spatial relationships between cell types in spatial transcriptomics data. Spatial proximity is a critical factor in cell-cell communication. The package calculates nearest neighbor distances between specified cell types and provides visualization tools to explore spatial patterns. Applications include studying cell-cell interactions, immune microenvironment characterization, and spatial organization of tissues.

Nonparametric and semiparametric estimations of the time-dependent ROC curve for an incomplete failure time data with surrogate failure time endpoints.

This package provides a streamlined and user-friendly framework for simulating data in state space models, particularly when the number of subjects/units (n) exceeds one, a scenario commonly encountered in social and behavioral sciences. This package was designed to generate data for the simulations performed in Pesigan, Russell, and Chow (2025) <doi:10.1037/met0000779>.

Stores objects (e.g. neural networks) that are needed for using Sojourn accelerometer methods. For more information, see Lyden K, Keadle S, Staudenmayer J, & Freedson P (2014) <doi:10.1249/MSS.0b013e3182a42a2d>, Ellingson LD, Schwabacher IJ, Kim Y, Welk GJ, & Cook DB (2016) <doi:10.1249/MSS.0000000000000915>, and Hibbing PR, Ellingson LD, Dixon PM, & Welk GJ (2018) <doi:10.1249/MSS.0000000000001486>.

Extends the SelectBoost approach to Generalized Additive Models for Location, Scale and Shape (GAMLSS). Implements bootstrap stability-selection across parameter-specific formulas (mu, sigma, nu, tau) via gamlss::stepGAIC(). Includes optional standardization of predictors and helper functions for corrected AIC calculation. More details can be found in Bertrand and Maumy (2024) <https://hal.science/hal-05352041> that highlights correlation-aware resampling to improve variable selection for GAMLSS and quantile regression when predictors are numerous and highly correlated.

Species sensitivity distributions are cumulative probability distributions which are fitted to toxicity concentrations for different species as described by Posthuma et al.(2001) <isbn:9781566705783>. The ssdtools package uses Maximum Likelihood to fit distributions such as the gamma, log-logistic, log-normal and log-normal log-normal mixture. Multiple distributions can be averaged using Akaike Information Criteria. Confidence intervals on hazard concentrations and proportions are produced by bootstrapping.

Allows objects to be stored on disc and automatically recalled into memory, as required, by delayed assignment.

Perform meta-analysis of single-case experiments, including calculating various effect size measures (SMD, PND, PEM and NAP) and probability combining (additive and multiplicative method), as discussed in Bulte and Onghena (2013) <doi:10.22237/jmasm/1383280020>.

Analysis tools to investigate changes in intercellular communication from scRNA-seq data. Using a Seurat object as input, the package infers which cell-cell interactions are present in the dataset and how these interactions change between two conditions of interest (e.g. young vs old). It relies on an internal database of ligand-receptor interactions (available for human, mouse and rat) that have been gathered from several published studies. Detection and differential analyses rely on permutation tests. The package also contains several tools to perform over-representation analysis and visualize the results. See Lagger, C. et al. (2023) <doi:10.1038/s43587-023-00514-x> for a full description of the methodology.

Scale alignment is a new procedure for rescaling dimensions of between-items multidimensional Rasch family models so that dimensions scores can be compared directly (Feuerstahler & Wilson, 2019; under review) <doi:10.1111/jedm.12209>. This package includes functions for implementing delta-dimensional alignment (DDA) and logistic regression alignment (LRA) for dichotomous or polytomous data. This function also includes a wrapper for models fit using the TAM package.

Calculates a modified Simplified Surface Energy Balance Index (SSEBI) and the Evaporative Fraction (EF) using geospatial raster data such as albedo and surface-air temperature difference (TSâ TA). The SSEBI is computed from albedo and TSâ TA to estimate surface moisture and evaporative dynamics, providing a robust assessment of surface dryness while accounting for atmospheric variations. Based on Roerink, Su, and Menenti (2000) <doi:10.1016/S1464-1909(99)00128-8>.

Send syslog protocol messages to a remote syslog server specified by host name and TCP network port.

Collection of shiny application styling that are the based on the GOV.UK Design System. See <https://design-system.service.gov.uk/components/> for details.