Computes the double bootstrap as discussed in McKnight, McKean, and Huitema (2000) <doi:10.1037/1082-989X.5.1.87>. The double bootstrap method provides a better fit for a linear model with autoregressive errors than ARIMA when the sample size is small.

Companion package of Arnaud Barat, Andreu Sansó, Maite Arilla-Osuna, Ruth Blasco, Iñaki Pérez-Fernández, Gabriel Cifuentes-Alcobenda, Rubén Llorente, Daniel Vivar-Rà os, Ella Assaf, Ran Barkai, Avi Gopher, & Jordi Rosell-Ardèvol (2025), "Quantifying Diversity through Entropy Decomposition. Insights into Hominin Occupation and Carcass Processing at Qesem cave".

This package provides a wide collection of univariate discrete data sets from various applied domains related to distribution theory. The functions allow quick, easy, and efficient access to 100 univariate discrete data sets. The data are related to different applied domains, including medical, reliability analysis, engineering, manufacturing, occupational safety, geological sciences, terrorism, psychology, agriculture, environmental sciences, road traffic accidents, demography, actuarial science, law, and justice. The documentation, along with associated references for further details and uses, is presented.

This package provides tools for describing parameters of algorithms in an abstract way. Description can include an id, a description, a domain (range or list of values), and a default value. dynparam can also convert parameter sets to a ParamHelpers format, in order to be able to use dynparam in conjunction with mlrMBO'.

Data quality assessments guided by a data quality framework introduced by Schmidt and colleagues, 2021 <doi:10.1186/s12874-021-01252-7> target the data quality dimensions integrity, completeness, consistency, and accuracy. The scope of applicable functions rests on the availability of extensive metadata which can be provided in spreadsheet tables. Either standardized (e.g. as html5 reports) or individually tailored reports can be generated. For an introduction into the specification of corresponding metadata, please refer to the package website <https://dataquality.qihs.uni-greifswald.de/VIN_Annotation_of_Metadata.html>.

Efficient Global Optimization (EGO) algorithm as described in "Roustant et al. (2012)" <doi:10.18637/jss.v051.i01> and adaptations for problems with noise ("Picheny and Ginsbourger, 2012") <doi:10.1016/j.csda.2013.03.018>, parallel infill, and problems with constraints.

Compute estimates and confidence intervals of weighted averages quickly and easily. Weighted averages are computed using data.table for speed. Confidence intervals are approximated using the delta method with either using known formulae or via algorithmic or numerical integration.

Collects libphonenumber jars required for the dialr package.

Cancer genomes contain large numbers of somatic alterations but few genes drive tumor development. Identifying cancer driver genes is critical for precision oncology. Most of current approaches either identify driver genes based on mutational recurrence or using estimated scores predicting the functional consequences of mutations. driveR is a tool for personalized or batch analysis of genomic data for driver gene prioritization by combining genomic information and prior biological knowledge. As features, driveR uses coding impact metaprediction scores, non-coding impact scores, somatic copy number alteration scores, hotspot gene/double-hit gene condition, phenolyzer gene scores and memberships to cancer-related KEGG pathways. It uses these features to estimate cancer-type-specific probability for each gene of being a cancer driver using the related task of a multi-task learning classification model. The method is described in detail in Ulgen E, Sezerman OU. 2021. driveR: driveR: a novel method for prioritizing cancer driver genes using somatic genomics data. BMC Bioinformatics <doi:10.1186/s12859-021-04203-7>.

Several tests for differential methylation in methylation array data, including one-sided differential mean and variance test. Methods used in the package refer to Dai, J, Wang, X, Chen, H and others (2021) "Incorporating increased variability in discovering cancer methylation markers", Biostatistics, submitted.

Deep Gaussian mixture models as proposed by Viroli and McLachlan (2019) <doi:10.1007/s11222-017-9793-z> provide a generalization of classical Gaussian mixtures to multiple layers. Each layer contains a set of latent variables that follow a mixture of Gaussian distributions. To avoid overparameterized solutions, dimension reduction is applied at each layer by way of factor models.

Real life data is muddy, fuzzy and unpredictable. This makes data manipulations tedious and bringing the data to right shape alone is a major chunk of work. Functions in this package help us get an understanding of dataframes to dramatically reduces data coding time.

Diversification is one of the most important concepts in portfolio management. This framework offers scholars, practitioners and policymakers a useful toolbox to measure diversification. Specifically, this framework provides recent diversification measures from the recent literature. These diversification measures are based on the works of Rudin and Morgan (2006) <doi:10.3905/jpm.2006.611807>, Choueifaty and Coignard (2008) <doi:10.3905/JPM.2008.35.1.40>, Vermorken et al. (2012) <doi:10.3905/jpm.2012.39.1.067>, Flores et al. (2017) <doi:10.3905/jpm.2017.43.4.112>, Calvet et al. (2007) <doi:10.1086/524204>, and Candelon, Fuerst and Hasse (2020).

The Data Driven I-V Feature Extraction is used to extract Current-Voltage (I-V) features from I-V curves. I-V curves indicate the relationship between current and voltage for a solar cell or Photovoltaic (PV) modules. The I-V features such as maximum power point (Pmp), shunt resistance (Rsh), series resistance (Rs),short circuit current (Isc), open circuit voltage (Voc), fill factor (FF), current at maximum power (Imp) and voltage at maximum power(Vmp) contain important information of the performance for PV modules. The traditional method uses the single diode model to model I-V curves and extract I-V features. This package does not use the diode model, but uses data-driven a method which select different linear parts of the I-V curves to extract I-V features. This method also uses a sampling method to calculate uncertainties when extracting I-V features. Also, because of the partially shaded array, "steps" occurs in I-V curves. The "Segmented Regression" method is used to identify steps in I-V curves. This material is based upon work supported by the U.S. Department of Energyâ s Office of Energy Efficiency and Renewable Energy (EERE) under Solar Energy Technologies Office (SETO) Agreement Number DE-EE0007140. Further information can be found in the following paper. [1] Ma, X. et al, 2019. <doi:10.1109/JPHOTOV.2019.2928477>.

Explore neural networks in a layer oriented way, the framework is intended to give the user total control of the internals of a net without much effort. Use classes like PerceptronLayer to create a layer of Percetron neurons, and specify how many you want. The package does all the tricky stuff internally leaving you focused in what you want. I wrote this package during a neural networks course to help me with the problem set.

This package provides functionality to infer trajectories from single-cell data, represent them into a common format, and adapt them. Other biological information can also be added, such as cellular grouping, RNA velocity and annotation. Saelens et al. (2019) <doi:10.1038/s41587-019-0071-9>.

Estimates fractional trophic level from quantitative and qualitative diet data and calculates electivity indices in R. Borstein (2020) <doi:10.1007/s10750-020-04417-5>.

This package provides methods for (auto)covariance/correlation function estimation in change point regression with stationary errors circumventing the pre-estimation of the underlying signal of the observations. Generic, first-order, (m+1)-gapped, difference-based autocovariance function estimator is based on M. Levine and I. Tecuapetla-Gómez (2023) <doi:10.48550/arXiv.1905.04578>. Bias-reducing, second-order, (m+1)-gapped, difference-based estimator is based on I. Tecuapetla-Gómez and A. Munk (2017) <doi:10.1111/sjos.12256>. Robust autocovariance estimator for change point regression with autoregressive errors is based on S. Chakar et al. (2017) <doi:10.3150/15-BEJ782>. It also includes a general projection-based method for covariance matrix estimation.

Computing and plotting the distance covariance and correlation function of a univariate or a multivariate time series. Both versions of biased and unbiased estimators of distance covariance and correlation are provided. Test statistics for testing pairwise independence are also implemented. Some data sets are also included. References include: a) Edelmann Dominic, Fokianos Konstantinos and Pitsillou Maria (2019). An Updated Literature Review of Distance Correlation and Its Applications to Time Series'. International Statistical Review, 87(2): 237--262. <doi:10.1111/insr.12294>. b) Fokianos Konstantinos and Pitsillou Maria (2018). Testing independence for multivariate time series via the auto-distance correlation matrix'. Biometrika, 105(2): 337--352. <doi:10.1093/biomet/asx082>. c) Fokianos Konstantinos and Pitsillou Maria (2017). Consistent testing for pairwise dependence in time series'. Technometrics, 59(2): 262--270. <doi:10.1080/00401706.2016.1156024>. d) Pitsillou Maria and Fokianos Konstantinos (2016). dCovTS: Distance Covariance/Correlation for Time Series'. R Journal, 8(2):324-340. <doi:10.32614/RJ-2016-049>.

Rare variant association test integrating variant position information. It aims to identify the presence of clusters of disease-risk variants in specific gene regions. For more details, please read the publication from Persyn et al. (2017) <doi:10.1371/journal.pone.0179364>.

Curated datasets and intuitive data management functions to streamline epidemiological data workflows. It is designed to support researchers in quickly accessing clean, structured data and applying essential cleaning, summarizing, visualization, and export operations with minimal effort. Whether you're preparing a cohort for analysis or creating reports, DIVINE makes the process more efficient, transparent, and reproducible.

Calculates key indicators such as fertility rates (Total Fertility Rate (TFR), General Fertility Rate (GFR), and Age Specific Fertility Rate (ASFR)) using Demographic and Health Survey (DHS) women/individual data, childhood mortality probabilities and rates such as Neonatal Mortality Rate (NNMR), Post-neonatal Mortality Rate (PNNMR), Infant Mortality Rate (IMR), Child Mortality Rate (CMR), and Under-five Mortality Rate (U5MR), and adult mortality indicators such as the Age Specific Mortality Rate (ASMR), Age Adjusted Mortality Rate (AAMR), Age Specific Maternal Mortality Rate (ASMMR), Age Adjusted Maternal Mortality Rate (AAMMR), Age Specific Pregnancy Related Mortality Rate (ASPRMR), Age Adjusted Pregnancy Related Mortality Rate (AAPRMR), Maternal Mortality Ratio (MMR) and Pregnancy Related Mortality Ratio (PRMR). In addition to the indicators, the DHS.rates package estimates sampling errors indicators such as Standard Error (SE), Design Effect (DEFT), Relative Standard Error (RSE) and Confidence Interval (CI). The package is developed according to the DHS methodology of calculating the fertility indicators and the childhood mortality rates outlined in the "Guide to DHS Statistics" (Croft, Trevor N., Aileen M. J. Marshall, Courtney K. Allen, et al. 2018, <https://dhsprogram.com/Data/Guide-to-DHS-Statistics/index.cfm>) and the DHS methodology of estimating the sampling errors indicators outlined in the "DHS Sampling and Household Listing Manual" (ICF International 2012, <https://dhsprogram.com/pubs/pdf/DHSM4/DHS6_Sampling_Manual_Sept2012_DHSM4.pdf>).

This package provides tools for constructing, manipulating and using distance metrics.

This package provides functions for planning clinical trials subject to a delayed treatment effect using assurance-based methods. Includes two shiny applications for interactive exploration, simulation, and visualisation of trial designs and outcomes. The methodology is described in: Salsbury JA, Oakley JE, Julious SA, Hampson LV (2024) "Assurance methods for designing a clinical trial with a delayed treatment effect" <doi:10.1002/sim.10136>, Salsbury JA, Oakley JE, Julious SA, Hampson LV (2024) "Adaptive clinical trial design with delayed treatment effects using elicited prior distributions" <doi:10.48550/arXiv.2509.07602>.