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Clustering via parsimonious Gaussian Mixtures of Experts using the MoEClust models introduced by Murphy and Murphy (2020) <doi:10.1007/s11634-019-00373-8>. This package fits finite Gaussian mixture models with a formula interface for supplying gating and/or expert network covariates using a range of parsimonious covariance parameterisations from the GPCM family via the EM/CEM algorithm. Visualisation of the results of such models using generalised pairs plots and the inclusion of an additional noise component is also facilitated. A greedy forward stepwise search algorithm is provided for identifying the optimal model in terms of the number of components, the GPCM covariance parameterisation, and the subsets of gating/expert network covariates.
Implementation of Multidimensional Top Scoring method for creativity assessment proposed in Boris Forthmann, Maciej Karwowski, Roger E. Beaty (2023) <doi:10.1037/aca0000571>.
Quantitative RT-PCR data are analyzed using generalized linear mixed models based on lognormal-Poisson error distribution, fitted using MCMC. Control genes are not required but can be incorporated as Bayesian priors or, when template abundances correlate with conditions, as trackers of global effects (common to all genes). The package also implements a lognormal model for higher-abundance data and a "classic" model involving multi-gene normalization on a by-sample basis. Several plotting functions are included to extract and visualize results. The detailed tutorial is available here: <https://matzlab.weebly.com/uploads/7/6/2/2/76229469/mcmc.qpcr.tutorial.v1.2.4.pdf>.
This package performs multivariate meta-analysis for high-dimensional data to integrate and collectively analyse individual-level data from multiple studies, as well as to combine summary estimates. This approach accounts for correlation between outcomes, incorporates withinâ and betweenâ study variability, handles missing values, and uses shrinkage estimation to accommodate high dimensionality. The MetaHD R package provides access to our multivariate meta-analysis approach, along with a comprehensive suite of existing meta-analysis methods, including fixed-effects and random-effects models, Fisherâ s method, Stoufferâ s method, the weighted Z method, Lancasterâ s method, the weighted Fisherâ s method, and vote-counting approach. A detailed vignette with example datasets and code for data preparation and analysis is available at <https://alyshadelivera.github.io/MetaHD_vignette/>.
This package provides a framework for deconvolution, alignment and postprocessing of 1-dimensional (1d) nuclear magnetic resonance (NMR) spectra, resulting in a data matrix of aligned signal integrals. The deconvolution part uses the algorithm described in Koh et al. (2009) <doi:10.1016/j.jmr.2009.09.003>. The alignment part is based on functions from the speaq package, described in Beirnaert et al. (2018) <doi:10.1371/journal.pcbi.1006018> and Vu et al. (2011) <doi:10.1186/1471-2105-12-405>. A detailed description and evaluation of an early version of the package, MetaboDecon1D v0.2.2', can be found in Haeckl et al. (2021) <doi:10.3390/metabo11070452>.
Predictive multivariate modelling for metabolomics. Types: Classification and regression. Methods: Partial Least Squares, Random Forest ans Elastic Net Data structures: Paired and unpaired Validation: repeated double cross-validation (Westerhuis et al. (2008)<doi:10.1007/s11306-007-0099-6>, Filzmoser et al. (2009)<doi:10.1002/cem.1225>) Variable selection: Performed internally, through tuning in the inner cross-validation loop.
Allows users to simulate matrix population models with particular characteristics based on aspects of life history such as mortality trajectories and fertility trajectories. Also allows the exploration of sampling error due to small sample size.
This package provides methods for analyzing and using quartets displayed on a collection of gene trees, primarily to make inferences about the species tree or network under the multi-species coalescent model. These include quartet hypothesis tests for the model, as developed by Mitchell et al. (2019) <doi:10.1214/19-EJS1576>, simplex plots of quartet concordance factors as presented by Allman et al. (2020) <doi:10.1101/2020.02.13.948083>, species tree inference methods based on quartet distances of Rhodes (2019) <doi:10.1109/TCBB.2019.2917204> and Yourdkhani and Rhodes (2019) <doi:10.1007/s11538-020-00773-4>, the NANUQ algorithm for inference of level-1 species networks of Allman et al. (2019) <doi:10.1186/s13015-019-0159-2>, the TINNIK algorithm for inference of the tree of blobs of an arbitrary network of Allman et al.(2022) <doi:10.1007/s00285-022-01838-9>, NANUQ+ routines for resolving multifurcations in the tree of blobs to cycles as in Rhodes et al.(2024) <doi:10.1186/s13015-025-00274-w>, and the ECToBlob algorithm for inference of a network with no anomalous quartets of Allman et al. (2026) (forthcoming). Software announcement by Rhodes et al. (2020) <doi:10.1093/bioinformatics/btaa868>.
This package performs monotonic binning of numeric risk factor in credit rating models (PD, LGD, EAD) development. All functions handle both binary and continuous target variable. Functions that use isotonic regression in the first stage of binning process have an additional feature for correction of minimum percentage of observations and minimum target rate per bin. Additionally, monotonic trend can be identified based on raw data or, if known in advance, forced by functions argument. Missing values and other possible special values are treated separately from so-called complete cases.
This package provides functions to read in and manipulate air quality model output from Models3-formatted files. This format is used by the Community Multiscale Air Quality (CMAQ) model.
Computes the prime implicants or a minimal disjunctive normal form for a logic expression presented by a truth table or a logic tree. Has been particularly developed for logic expressions resulting from a logic regression analysis, i.e. logic expressions typically consisting of up to 16 literals, where the prime implicants are typically composed of a maximum of 4 or 5 literals.
This package provides functions for reading (tab, csv, Bruker fid, Ciphergen XML, mzXML, mzML, imzML, Analyze 7.5, CDF, mMass MSD) and writing (tab, csv, mMass MSD, mzML, imzML) different file formats of mass spectrometry data into/from MALDIquant objects.
This package provides utilities for estimation for the multivariate inverse Gaussian distribution of Minami (2003) <doi:10.1081/STA-120025379>, including random vector generation and explicit estimators of the location vector and scale matrix. The package implements kernel density estimators discussed in Belzile, Desgagnes, Genest and Ouimet (2024) <doi:10.48550/arXiv.2209.04757> for smoothing multivariate data on half-spaces.
Acoustic template detection and monitoring database interface. Create, modify, save, and use templates for detection of animal vocalizations. View, verify, and extract results. Upload a MySQL schema to a existing instance, manage survey metadata, write and read templates and detections locally or to the database.
Offers an easy and automated way to scale up individual-level space use analysis to that of groups. Contains a function from the move package to calculate a dynamic Brownian bridge movement model from movement data for individual animals, as well as functions to visualize and quantify space use for individuals aggregated in groups. Originally written with passive acoustic telemetry in mind, this package also provides functionality to account for unbalanced acoustic receiver array designs, and satellite tag data.
This package provides a simple and the early stage package for matrix profile based on the paper of Chin-Chia Michael Yeh, Yan Zhu, Liudmila Ulanova, Nurjahan Begum, Yifei Ding, Hoang Anh Dau, Diego Furtado Silva, Abdullah Mueen, and Eamonn Keogh (2016) <DOI:10.1109/ICDM.2016.0179>. This package calculates all-pairs-similarity for a given window size for time series data.
Semi-parametric approach for sparse canonical correlation analysis which can handle mixed data types: continuous, binary and truncated continuous. Bridge functions are provided to connect Kendall's tau to latent correlation under the Gaussian copula model. The methods are described in Yoon, Carroll and Gaynanova (2020) <doi:10.1093/biomet/asaa007> and Yoon, Mueller and Gaynanova (2021) <doi:10.1080/10618600.2021.1882468>.
This package provides a collection of multivariate nonparametric methods, selected in part to support an MS level course in nonparametric statistical methods. Methods include adjustments for multiple comparisons, implementation of multivariate Mann-Whitney-Wilcoxon testing, inversion of these tests to produce a confidence region, some permutation tests for linear models, and some algorithms for calculating exact probabilities associated with one- and two- stage testing involving Mann-Whitney-Wilcoxon statistics. Supported by grant NSF DMS 1712839. See Kolassa and Seifu (2013) <doi:10.1016/j.acra.2013.03.006>.
Evolutionary black box optimization algorithms building on the bbotk package. miesmuschel offers both ready-to-use optimization algorithms, as well as their fundamental building blocks that can be used to manually construct specialized optimization loops. The Mixed Integer Evolution Strategies as described by Li et al. (2013) <doi:10.1162/EVCO_a_00059> can be implemented, as well as the multi-objective optimization algorithms NSGA-II by Deb, Pratap, Agarwal, and Meyarivan (2002) <doi:10.1109/4235.996017>.
Advanced methods for a valuable quantitative environmental risk assessment using Bayesian inference of survival Data with toxicokinetics toxicodynamics (TKTD) models. Among others, it facilitates Bayesian inference of the general unified threshold model of survival (GUTS). See models description in Jager et al. (2011) <doi:10.1021/es103092a> and implementation using Bayesian inference in Baudrot and Charles (2019) <doi:10.1038/s41598-019-47698-0>.
Estimation of models with dependent variable left-censored at zero. Null values may be caused by a selection process Cragg (1971) <doi:10.2307/1909582>, insufficient resources Tobin (1958) <doi:10.2307/1907382>, or infrequency of purchase Deaton and Irish (1984) <doi:10.1016/0047-2727(84)90067-7>.
Meteorological Tools following the FAO56 irrigation paper of Allen et al. (1998) [1]. Functions for calculating: reference evapotranspiration (ETref), extraterrestrial radiation (Ra), net radiation (Rn), saturation vapor pressure (satVP), global radiation (Rs), soil heat flux (G), daylight hours, and more. [1] Allen, R. G., Pereira, L. S., Raes, D., & Smith, M. (1998). Crop evapotranspiration-Guidelines for computing crop water requirements-FAO Irrigation and drainage paper 56. FAO, Rome, 300(9).
Helper functions to standardizes common workflows in the USGS Data Science Community of Practice to produce more robust, reproducible pipelines. It contains helper functions to standardize (1) the organization of project repositories and (2) the creation ofpipelines from the targets R Package (Landau et al. (2026) <doi:10.5281/zenodo.18555866>), using the DS CoP best practices. We draw upon community developed best practices as well as certain USGS-specific requirements. See Shrycock et al. (2023) <doi:10.3133/tm7B2> for examples of these USGS requirements.
Calculate a multivariate functional principal component analysis for data observed on different dimensional domains. The estimation algorithm relies on univariate basis expansions for each element of the multivariate functional data (Happ & Greven, 2018) <doi:10.1080/01621459.2016.1273115>. Multivariate and univariate functional data objects are represented by S4 classes for this type of data implemented in the package funData'. For more details on the general concepts of both packages and a case study, see Happ-Kurz (2020) <doi:10.18637/jss.v093.i05>.