This package provides a comprehensive framework for early epidemic detection through school absenteeism surveillance. The package offers three core functionalities: (1) simulation of population structures, epidemic spread, and resulting school absenteeism patterns; (2) implementation of surveillance models that generate alerts for impending epidemics based on absenteeism data and (3) evaluation of alert timeliness and accuracy through alert time quality metrics to optimize model parameters. These tools enable public health officials and researchers to develop and assess early warning systems before implementation. Methods are based on research published in Vanderkruk et al. (2023) <doi:10.1186/s12889-023-15747-z> and Ward et al. (2019) <doi:10.1186/s12889-019-7521-7>.

Diff, patch and merge for data frames. Document changes in data sets and use them to apply patches. Changes to data can be made visible by using render_diff(). The V8 package is used to wrap the daff.js JavaScript library which is included in the package.

This package provides a set of tools for relational and event analysis, including two- and one-mode network brokerage and structural measures, and helper functions optimized for relational event analysis with large datasets, including creating relational risk sets, computing network statistics, estimating relational event models, and simulating relational event sequences. For more information on relational event models, see Butts (2008) <doi:10.1111/j.1467-9531.2008.00203.x>, Lerner and Lomi (2020) <doi:10.1017/nws.2019.57>, Bianchi et al. (2024) <doi:10.1146/annurev-statistics-040722-060248>, and Butts et al. (2023) <doi:10.1017/nws.2023.9>. In terms of the structural measures in this package, see Leal (2025) <doi:10.1177/00491241251322517>, Burchard and Cornwell (2018) <doi:10.1016/j.socnet.2018.04.001>, and Fujimoto et al. (2018) <doi:10.1017/nws.2018.11>. This package was developed with support from the National Science Foundationâ s (NSF) Human Networks and Data Science Program (HNDS) under award number 2241536 (PI: Diego F. Leal). Any opinions, findings, and conclusions, or recommendations expressed in this material are those of the authors and do not necessarily reflect the views of the NSF.

Identification of causal effects from arbitrary observational and experimental probability distributions via do-calculus and standard probability manipulations using a search-based algorithm by Tikka, Hyttinen and Karvanen (2021) <doi:10.18637/jss.v099.i05>. Allows for the presence of mechanisms related to selection bias (Bareinboim and Tian, 2015) <doi:10.1609/aaai.v29i1.9679>, transportability (Bareinboim and Pearl, 2014) <http://ftp.cs.ucla.edu/pub/stat_ser/r443.pdf>, missing data (Mohan, Pearl, and Tian, 2013) <http://ftp.cs.ucla.edu/pub/stat_ser/r410.pdf>) and arbitrary combinations of these. Also supports identification in the presence of context-specific independence (CSI) relations through labeled directed acyclic graphs (LDAG). For details on CSIs see (Corander et al., 2019) <doi:10.1016/j.apal.2019.04.004>.

Implementation of three methods based on the diversity forest (DF) algorithm (Hornung, 2022, <doi:10.1007/s42979-021-00920-1>), a split-finding approach that enables complex split procedures in random forests. The package includes: 1. Interaction forests (IFs) (Hornung & Boulesteix, 2022, <doi:10.1016/j.csda.2022.107460>): Model quantitative and qualitative interaction effects using bivariable splitting. Come with the Effect Importance Measure (EIM), which can be used to identify variable pairs that have well-interpretable quantitative and qualitative interaction effects with high predictive relevance. 2. Two random forest-based variable importance measures (VIMs) for multi-class outcomes: the class-focused VIM, which ranks covariates by their ability to distinguish individual outcome classes from the others, and the discriminatory VIM, which measures overall covariate influence irrespective of class-specific relevance. 3. The basic form of diversity forests that uses conventional univariable, binary splitting (Hornung, 2022). Except for the multi-class VIMs, all methods support categorical, metric, and survival outcomes. The package includes visualization tools for interpreting the identified covariate effects. Built as a fork of the ranger R package (main author: Marvin N. Wright), which implements random forests using an efficient C++ implementation.

Use leaf physiognomic methods to reconstruct mean annual temperature (MAT), mean annual precipitation (MAP), and leaf dry mass per area (Ma), along with other useful quantitative leaf traits. Methods in this package described in Lowe et al. (in review).

Edit and validate taxonomic data in compliance with Darwin Core standards (Darwin Core Taxon class <https://dwc.tdwg.org/terms/#taxon>).

This package provides functions to accompany Wayne W. Daniel's Biostatistics: A Foundation for Analysis in the Health Sciences, Tenth Edition.

An implementation by Chen, Li, and Zhang (2022) <doi: 10.1093/bioadv/vbac041> of the Depth Importance in Precision Medicine (DIPM) method in Chen and Zhang (2022) <doi:10.1093/biostatistics/kxaa021> and Chen and Zhang (2020) <doi:10.1007/978-3-030-46161-4_16>. The DIPM method is a classification tree that searches for subgroups with especially poor or strong performance in a given treatment group.

Tests for context-dependent selection on cancer driver genes using somatic mutation data. The package implements the DiffDriver statistical framework to assess whether the strength of positive selection on mutations in a driver gene is associated with tumor- or individual-level context variables, such as clinical traits, genomic features, or immune microenvironment subtypes. DiffDriver estimates individual- and position-specific background mutation rates, models selection as a deviation from the background rate using functional annotations, and tests context effects through a latent-variable logistic model. It provides utilities for preparing mutation and annotation data, fitting differential-selection models, running gene-level association tests, summarizing candidate genes, and visualizing mutation patterns. The method is described in Zhou et al. (2026) "Detecting context-dependent selection on cancer driver genes with DiffDriver" <doi:10.64898/2026.04.06.716771>.

This package provides a Bayesian framework for parameter inference in differential equations. This approach offers a rigorous methodology for parameter inference as well as modeling the link between unobservable model states and parameters, and observable quantities. Provides templates for the DE model, the observation model and data likelihood, and the model parameters and their prior distributions. A Markov chain Monte Carlo (MCMC) procedure processes these inputs to estimate the posterior distributions of the parameters and any derived quantities, including the model trajectories. Further functionality is provided to facilitate MCMC diagnostics and the visualisation of the posterior distributions of model parameters and trajectories.

The distributed expectation maximization algorithms are used to solve parameters of multivariate Gaussian mixture models. The philosophy of the package is described in Guo, G. (2022) <doi:10.1080/02664763.2022.2053949>.

This package provides a set of three two-census methods to the estimate the degree of death registration coverage for a population. Implemented methods include the Generalized Growth Balance method (GGB), the Synthetic Extinct Generation method (SEG), and a hybrid of the two, GGB-SEG. Each method offers automatic estimation, but users may also specify exact parameters or use a graphical interface to guess parameters in the traditional way if desired.

An implementation of major general-purpose mechanisms for privatizing statistics, models, and machine learners, within the framework of differential privacy of Dwork et al. (2006) <doi:10.1007/11681878_14>. Example mechanisms include the Laplace mechanism for releasing numeric aggregates, and the exponential mechanism for releasing set elements. A sensitivity sampler (Rubinstein & Alda, 2017) <arXiv:1706.02562> permits sampling target non-private function sensitivity; combined with the generic mechanisms, it permits turn-key privatization of arbitrary programs.

Create quick and easy dot-and-whisker plots of regression results. It takes as input either (1) a coefficient table in standard form or (2) one (or a list of) fitted model objects (of any type that has methods implemented in the parameters package). It returns ggplot objects that can be further customized using tools from the ggplot2 package. The package also includes helper functions for tasks such as rescaling coefficients or relabeling predictor variables. See more methodological discussion of the visualization and data management methods used in this package in Kastellec and Leoni (2007) <doi:10.1017/S1537592707072209> and Gelman (2008) <doi:10.1002/sim.3107>.

Analysis of agreement for nominal data between two raters using the Delta model. This model is proposed as an alternative to the widespread measure Cohen kappa coefficient, which performs poorly when the marginal distributions are very asymmetric (Martin-Andres and Femia-Marzo (2004), <doi:10.1348/000711004849268>; Martin-Andres and Femia-Marzo (2008) <doi:10.1080/03610920701669884>). The package also contains a function to perform a massive analysis of multiple raters against a gold standard. A shiny app is also provided to obtain the measures of nominal agreement between two raters.

Mechanistically models/predicts the phenology (macro-phases) of 10 crop plants (trained on a big dataset over 80 years derived from the German weather service (DWD) <https://opendata.dwd.de/>). Can be applied for remote sensing purposes, dynamically check the best subset of available covariates for the given dataset and crop.

This package provides the ability to display something analogous to Python's docstrings within R. By allowing the user to document their functions as comments at the beginning of their function without requiring putting the function into a package we allow more users to easily provide documentation for their functions. The documentation can be viewed just like any other help files for functions provided by packages as well.

This package provides methods to detect differential item functioning (DIF) in dichotomous, polytomous, and continuous items, using both classical and modern approaches. These include Mantel-Haenszel procedures, logistic regression (including ordinal models), and regularization-based methods such as LASSO. Uniform and non-uniform DIF effects can be detected, and some methods support multiple focal groups. The package also provides tools for anchor purification, rest score matching, effect size estimation, and DIF simulation. See Magis, Beland, Tuerlinckx, and De Boeck (2010, Behavior Research Methods, 42, 847â 862, <doi:10.3758/BRM.42.3.847>) for a general overview.

This package contains the function used to create the Dandelion Plot. Dandelion Plot is a visualization method for R-mode Exploratory Factor Analysis.

Automates quality verification of recurring external dataset deliveries. For each new file arrival, it runs single-snapshot quality checks, compares the file to the previous delivery, writes a self-contained HTML report, and records summary statistics in a local SQLite database for long-term trend tracking. Supports CSV and fixed-width formats. Custom organisation-specific checks can be supplied as plain R files.

This package performs DIFlasso as proposed by Tutz and Schauberger (2015) <doi:10.1007/s11336-013-9377-6>, a method to detect DIF (Differential Item Functioning) in Rasch Models. It can handle settings with many variables and also metric variables.

Allows the computation of clustering coefficients for directed and weighted networks by using different approaches. It allows to compute clustering coefficients that are not present in igraph package. A description of clustering coefficients can be found in "Directed clustering in weighted networks: a new perspective", Clemente, G.P., Grassi, R. (2017), <doi:10.1016/j.chaos.2017.12.007>.

First using dada2 R tools to analyse metabarcode data, the DBTC package then uses the BLAST algorithm to search unknown sequences against local databases, and then takes reduced matched results and provides best taxonomic assignments.