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This package provides a unified framework for detecting spatially variable genes (SVGs) in spatial transcriptomics data. This package integrates multiple state-of-the-art SVG detection methods including MERINGUE (Moran's I based spatial autocorrelation), Giotto binSpect (binary spatial enrichment test), SPARK-X (non-parametric kernel-based test), and nnSVG (nearest-neighbor Gaussian processes). Each method is implemented with optimized performance through vectorization, parallelization, and C++ acceleration where applicable. Methods are described in Miller et al. (2021) <doi:10.1101/gr.271288.120>, Dries et al. (2021) <doi:10.1186/s13059-021-02286-2>, Zhu et al. (2021) <doi:10.1186/s13059-021-02404-0>, and Weber et al. (2023) <doi:10.1038/s41467-023-39748-z>.
Allows the user to animate shiny elements when scrolling to view them. The animations are activated using the scrollrevealjs library. See <https://scrollrevealjs.org/> for more information.
Spectral and Average Autocorrelation Zero Distance Density ('sazed') is a method for estimating the season length of a seasonal time series. sazed is aimed at practitioners, as it employs only domain-agnostic preprocessing and does not depend on parameter tuning or empirical constants. The computation of sazed relies on the efficient autocorrelation computation methods suggested by Thibauld Nion (2012, URL: <https://etudes.tibonihoo.net/literate_musing/autocorrelations.html>) and by Bob Carpenter (2012, URL: <https://lingpipe-blog.com/2012/06/08/autocorrelation-fft-kiss-eigen/>).
This package provides functions to estimate a strategic selection estimator. A strategic selection estimator is an agent error model in which the two random components are not assumed to be orthogonal. In addition this package provides generic functions to print and plot objects of its class as well as the necessary functions to create tables for LaTeX. There is also a function to create dyadic data sets.
Generate data objects from XML versions of the Swiss Register of Plant Protection Products. An online version of the register can be accessed at <https://www.psm.admin.ch/de/produkte>. There is no guarantee of correspondence of the data read in using this package with that online version, or with the original registration documents. Also, the Federal Food Safety and Veterinary Office, coordinating the authorisation of plant protection products in Switzerland, does not answer requests regarding this package.
Full text, in data frames containing one row per verse, of the Standard Works of The Church of Jesus Christ of Latter-day Saints (LDS). These are the Old Testament, (KJV), the New Testament (KJV), the Book of Mormon, the Doctrine and Covenants, and the Pearl of Great Price.
Sequential Poisson sampling is a variation of Poisson sampling for drawing probability-proportional-to-size samples with a given number of units, and is commonly used for price-index surveys. This package gives functions to draw stratified sequential Poisson samples according to the method by Ohlsson (1998, ISSN:0282-423X), as well as other order sample designs by Rosén (1997, <doi:10.1016/S0378-3758(96)00186-3>), and generate approximate bootstrap replicate weights according to the generalized bootstrap method by Beaumont and Patak (2012, <doi:10.1111/j.1751-5823.2011.00166.x>).
This package provides a toolkit for stratified medicine, subgroup identification, and precision medicine. Current tools include (1) filtering models (reduce covariate space), (2) patient-level estimate models (counterfactual patient-level quantities, such as the conditional average treatment effect), (3) subgroup identification models (find subsets of patients with similar treatment effects), and (4) treatment effect estimation and inference (for the overall population and discovered subgroups). These tools can be customized and are directly used in PRISM (patient response identifiers for stratified medicine; Jemielita and Mehrotra 2019 <doi:10.48550/arXiv.1912.03337>).
This package provides a set of tools for examining the design and analysis aspects of stepped wedge cluster randomized trials (SW CRT) based on a repeated cross-sectional or cohort sampling scheme (Hussey MA and Hughes JP (2007) Contemporary Clinical Trials 28:182-191).
Character vector to numerical translation in Euros from Spanish spelled monetary quantities. Reverse translation from integer to Spanish. Upper limit is up to the millions range. Geocoding via Cadastral web site.
Package provides a set of tools for robust estimation and inference for models with sample selectivity and endogenous treatment model. For details, see Zhelonkin and Ronchetti (2021) <doi:10.18637/jss.v099.i04>.
This tool fits a non-parametric Bayesian model called a "hierarchically coupled mixture model with local dependence (HCMM-LD)" to the original microdata in order to generate synthetic microdata for privacy protection. The non-parametric feature of the adopted model is useful for capturing the joint distribution of the original input data in a highly flexible manner, leading to the generation of synthetic data whose distributional features are similar to that of the input data. The package allows the original input data to have missing values and impute them with the posterior predictive distribution, so no missing values exist in the synthetic data output. The method builds on the work of Murray and Reiter (2016) <doi:10.1080/01621459.2016.1174132>.
Is designed to interactively and reproducibly visualize and filter SNP (single-nucleotide polymorphism) datasets. This R-based implementation of SNP and genotype filters facilitates an interactive and iterative SNP filtering pipeline, which can be documented reproducibly via rmarkdown'. SNPfiltR contains functions for visualizing various quality and missing data metrics for a SNP dataset, and then filtering the dataset based on user specified cutoffs. All functions take vcfR objects as input, which can easily be generated by reading standard vcf (variant call format) files into R using the R package vcfR authored by Knaus and Grünwald (2017) <doi:10.1111/1755-0998.12549>. Each SNPfiltR function can return a newly filtered vcfR object, which can then be written to a local directory in standard vcf format using the vcfR package, for downstream population genetic and phylogenetic analyses.
Inspired by the art and color research of Sanzo Wada (1883-1967), his "Dictionary Of Color Combinations" (2011, ISBN:978-4861522475), and the interactive site by Dain M. Blodorn Kim <https://github.com/dblodorn/sanzo-wada>, this package brings Wada's color combinations to R for easy use in data visualizations. This package honors 60 of Wada's color combinations: 20 duos, 20 trios, and 20 quads.
Allows TailwindCSS to be used in Shiny apps with just-in-time compiling, custom css with @apply directive, and custom tailwind configurations.
Three new methods to perform outlier detection in a survival context. In total there are six methods provided, the first three methods are traditional residual-based outlier detection methods, the second three are the concordance-based. Package developed during the work on the two following publications: Pinto J., Carvalho A. and Vinga S. (2015) <doi:10.5220/0005225300750082>; Pinto J.D., Carvalho A.M., Vinga S. (2015) <doi:10.1007/978-3-319-27926-8_22>.
This package provides a pipeline that can process single or multiple Single Cell RNAseq samples primarily specializes in Clustering and Dimensionality Reduction. Meanwhile we use common cell type marker genes for T cells, B cells, Myeloid cells, Epithelial cells, and stromal cells (Fiboblast, Endothelial cells, Pericyte, Smooth muscle cells) to visualize the Seurat clusters, to facilitate labeling them by biological names. Once users named each cluster, they can evaluate the quality of them again and find the de novo marker genes also.
Downloads and tidies the San Francisco Public Utilities Commission Beach Water Quality Monitoring Program data. Data sets can be downloaded per beach, or the raw data can be downloaded. See <https://sfwater.org/cfapps/lims/beachmain1.cfm>.
Easily analyze and visualize differences between samples (e.g., benchmark comparisons, nonresponse comparisons in surveys) on three levels. The comparisons can be univariate, bivariate or multivariate. On univariate level the variables of interest of a survey and a comparison survey (i.e. benchmark) are compared, by calculating one of several difference measures (e.g., relative difference in mean), and an average difference between the surveys. On bivariate level a function can calculate significant differences in correlations for the surveys. And on multivariate levels a function can calculate significant differences in model coefficients between the surveys of comparison. All of those differences can be easily plotted and outputted as a table. For more detailed information on the methods and example use see Rohr, B., Silber, H., & Felderer, B. (2024). Comparing the Accuracy of Univariate, Bivariate, and Multivariate Estimates across Probability and Nonprobability Surveys with Population Benchmarks. Sociological Methodology <doi:10.1177/00811750241280963>.
This package provides a collection of simple parameter estimation and tests for the comparison of multivariate means and variation, to accompany Chapters 4 and 5 of the book Multivariate Statistical Methods. A Primer (5th edition), by Manly BFJ, Navarro Alberto JA & Gerow K (2024) <doi:10.1201/9781003453482>.
Output colors used in literal vectors, palettes and plot objects (ggplot).
Simultaneous tests and confidence intervals are provided for one-way experimental designs with one or many normally distributed, primary response variables (endpoints). Differences (Hasler and Hothorn, 2011 <doi:10.2202/1557-4679.1258>) or ratios (Hasler and Hothorn, 2012 <doi:10.1080/19466315.2011.633868>) of means can be considered. Various contrasts can be chosen, unbalanced sample sizes are allowed as well as heterogeneous variances (Hasler and Hothorn, 2008 <doi:10.1002/bimj.200710466>) or covariance matrices (Hasler, 2014 <doi:10.1515/ijb-2012-0015>).
Randomization of presence/absence species distribution raster data with or without including spatial structure for calculating standardized effect sizes and testing null hypothesis. The randomization algorithms are based on classical algorithms for matrices (Gotelli 2000, <doi:10.2307/177478>) implemented for raster data.
Estimate necessary sample sizes for comparing the location of data from two groups or categories when the distribution of the data is skewed. The package offers a non-parametric method for a Wilcoxon Mann-Whitney test of location shift as well as methods for several generalized linear models, for instance, Gamma regression.