This package produces tables with the level of replication (number of replicates) and the experimental uncoded values of the quantitative factors to be used for rotatable Central Composite Design (CCD) experimentation and a 2-D contour plot of the corresponding variance of the predicted response according to Mead et al. (2012) <doi:10.1017/CBO9781139020879> design_ccd(), and analyzes CCD data with response surface methodology ccd_analysis(). A rotatable CCD provides values of the variance of the predicted response that are concentrically distributed around the average treatment combination used in the experimentation, which with uniform precision (implied by the use of several replicates at the average treatment combination) improves greatly the search and finding of an optimum response. These properties of a rotatable CCD represent undeniable advantages over the classical factorial design, as discussed by Panneton et al. (1999) <doi:10.13031/2013.13267> and Mead et al. (2012) <doi:10.1017/CBO9781139020879.018> among others.

This package provides functions to calculate Sample Number and Average Sample Number for Repetitive Group Sampling Plan Based on Cpk as given in Aslam et al. (2013) (<DOI:10.1080/00949655.2012.663374>).

This package provides an easy way to report the results of ROC analysis, including: 1. an ROC curve. 2. the value of Cutoff, AUC (Area Under Curve), ACC (accuracy), SEN (sensitivity), SPE (specificity), PLR (positive likelihood ratio), NLR (negative likelihood ratio), PPV (positive predictive value), NPV (negative predictive value), PPA (percentage of positive accordance), NPA (percentage of negative accordance), TPA (percentage of total accordance), KAPPA (kappa value).

This package provides a flexible and streamlined pipeline for formatting, analyzing, and visualizing omics data, regardless of omics type (e.g. transcriptomics, proteomics, metabolomics). The package includes tools for shaping input data into analysis-ready structures, fitting linear or mixed-effect models, extracting key contrasts, and generating a rich variety of ready-to-use publication-quality plots. Designed for transparency and reproducibility across a wide range of study designs, with customizable components for statistical modeling.

The regression discontinuity (RD) design is a popular quasi-experimental design for causal inference and policy evaluation. Under the local randomization approach, RD designs can be interpreted as randomized experiments inside a window around the cutoff. This package provides tools to perform randomization inference for RD designs under local randomization: rdrandinf() to perform hypothesis testing using randomization inference, rdwinselect() to select a window around the cutoff in which randomization is likely to hold, rdsensitivity() to assess the sensitivity of the results to different window lengths and null hypotheses and rdrbounds() to construct Rosenbaum bounds for sensitivity to unobserved confounders. See Cattaneo, Titiunik and Vazquez-Bare (2016) <https://rdpackages.github.io/references/Cattaneo-Titiunik-VazquezBare_2016_Stata.pdf> for further methodological details.

This package provides a comprehensive suite of functions to perform and visualise pairwise and network meta-analysis with aggregate binary or continuous missing participant outcome data. The package covers core Bayesian one-stage models implemented in a systematic review with multiple interventions, including fixed-effect and random-effects network meta-analysis, meta-regression, evaluation of the consistency assumption via the node-splitting approach and the unrelated mean effects model (original and revised model proposed by Spineli, (2022) <doi:10.1177/0272989X211068005>), and sensitivity analysis (see Spineli et al., (2021) <doi:10.1186/s12916-021-02195-y>). Missing participant outcome data are addressed in all models of the package (see Spineli, (2019) <doi:10.1186/s12874-019-0731-y>, Spineli et al., (2019) <doi:10.1002/sim.8207>, Spineli, (2019) <doi:10.1016/j.jclinepi.2018.09.002>, and Spineli et al., (2021) <doi:10.1002/jrsm.1478>). The robustness to primary analysis results can also be investigated using a novel intuitive index (see Spineli et al., (2021) <doi:10.1177/0962280220983544>). Methods to evaluate the transitivity assumption using trial dissimilarities and hierarchical clustering are provided (see Spineli, (2024) <doi:10.1186/s12874-024-02436-7>, and Spineli et al., (2025) <doi:10.1002/sim.70068>). A novel index to facilitate interpretation of local inconsistency is also available (see Spineli, (2024) <doi:10.1186/s13643-024-02680-4>) The package also offers a rich, user-friendly visualisation toolkit that aids in appraising and interpreting the results thoroughly and preparing the manuscript for journal submission. The visualisation tools comprise the network plot, forest plots, panel of diagnostic plots, heatmaps on the extent of missing participant outcome data in the network, league heatmaps on estimation and prediction, rankograms, Bland-Altman plot, leverage plot, deviance scatterplot, heatmap of robustness, barplot of Kullback-Leibler divergence, heatmap of comparison dissimilarities and dendrogram of comparison clustering. The package also allows the user to export the results to an Excel file at the working directory.

Rcmdr menu support for many of the functions in the HH package. The focus is on menu items for functions we use in our introductory courses.

R-based access to mass-spectrometry (MS) data. While many packages exist to process MS data, many of these make it difficult to access the underlying mass-to-charge ratio (m/z), intensity, and retention time of the files themselves. This package is designed to format MS data in a tidy fashion and allows the user perform the plotting and analysis.

This package provides a Tidy implementation of grouping sets', rollup and cube - extensions of the group_by clause that allow for computing multiple group_by clauses in a single statement. For more detailed information on these functions, please refer to "Enhanced Aggregation, Cube, Grouping and Rollup" <https://cwiki.apache.org/confluence/display/Hive/Enhanced+Aggregation%2C+Cube%2C+Grouping+and+Rollup>.

These functions take a character vector as input, identify and cluster similar values, and then merge clusters together so their values become identical. The functions are an implementation of the key collision and ngram fingerprint algorithms from the open source tool Open Refine <https://openrefine.org/>. More info on key collision and ngram fingerprint can be found here <https://openrefine.org/docs/technical-reference/clustering-in-depth>.

Facilitates efficient polygon search using kd trees. Coordinate level spatial data can be aggregated to higher geographical identities like census blocks, ZIP codes or police district boundaries. This process requires mapping each point in the given data set to a particular identity of the desired geographical hierarchy. Unless efficient data structures are used, this can be a daunting task. The operation point.in.polygon() from the package sp is computationally expensive. Here, we exploit kd-trees as efficient nearest neighbor search algorithm to dramatically reduce the effective number of polygons being searched.

Provide helper functions for package developers to create active bindings that looks like data embedded in the package, but are downloaded from remote sources.

An example package which shows use of NLopt functionality from C++ via Rcpp without requiring linking, and relying just on nloptr thanks to the exporting API added there by Jelmer Ypma. This package is a fully functioning, updated, and expanded version of the initial example by Julien Chiquet at <https://github.com/jchiquet/RcppArmadilloNLoptExample> also containing a large earlier pull request of mine.

Quickly imports, processes, analyzes, and visualizes mass-spectrometric data. Includes functions for easily extracting specific data and measurements from large (multi-gigabyte) raw Bruker data files, as well as a set of S3 object classes for manipulating and measuring mass spectrometric peaks and plotting peaks and spectra using the ggplot2 package.

We provide functions to perform an empirical small telescopes analysis. This package contains 2 functions, SmallTelescopes() and EstimatePower(). Users only need to call SmallTelescopes() to conduct the analysis. For more information on small telescopes analysis see Uri Simonsohn (2015) <doi:10.1177/0956797614567341>.

Interface for the Google Ads API'. Google Ads is an online advertising service that enables advertisers to display advertising to web users (see <https://developers.google.com/google-ads/> for more information).

Fits MIDAS denoising autoencoder models for multiple imputation of missing data, generates multiply-imputed datasets, computes imputation means, and runs Rubin's rules regression analysis. Wraps the MIDAS2 Python engine via a local FastAPI server over HTTP', so no reticulate dependency is needed at runtime. Methods are described in Lall and Robinson (2022) <doi:10.1017/pan.2020.49> and Lall and Robinson (2023) <doi:10.18637/jss.v107.i09>.

An R interface to the Chemistry Development Kit, a Java library for chemoinformatics. Given the size of the library itself, this package is not expected to change very frequently. To make use of the CDK within R, it is suggested that you use the rcdk package. Note that it is possible to directly interact with the CDK using rJava'. However rcdk exposes functionality in a more idiomatic way. The CDK library itself is released as LGPL and the sources can be obtained from <https://github.com/cdk/cdk>.

This is a meta-package designed to support the installation of Rmosek (>= 6.0) and bring the optimization facilities of MOSEK (>= 6.0) to the R-language. The interface supports large-scale optimization of many kinds: Mixed-integer and continuous linear, second-order cone, exponential cone and power cone optimization, as well as continuous semidefinite optimization. Rmosek and the R-language are open-source projects. MOSEK is a proprietary product, but unrestricted trial and academic licenses are available.

We provide a toolbox to fit and simulate a univariate or multivariate damped random walk process that is also known as an Ornstein-Uhlenbeck process or a continuous-time autoregressive model of the first order, i.e., CAR(1) or CARMA(1, 0). This process is suitable for analyzing univariate or multivariate time series data with irregularly-spaced observation times and heteroscedastic measurement errors. When it comes to the multivariate case, the number of data points (measurements/observations) available at each observation time does not need to be the same, and the length of each time series can vary. The number of time series data sets that can be modeled simultaneously is limited to ten in this version of the package. We use Kalman-filtering to evaluate the resulting likelihood function, which leads to a scalable and efficient computation in finding maximum likelihood estimates of the model parameters or in drawing their posterior samples. Please pay attention to loading the data if this package is used for astronomical data analyses; see the details in the manual. Also see Hu and Tak (2020) <arXiv:2005.08049>.

Mixture Composer (Biernacki (2015) <https://inria.hal.science/hal-01253393v1>) is a project to perform clustering using mixture models with heterogeneous data and partially missing data. Mixture models are fitted using a SEM algorithm. It includes 8 models for real, categorical, counting, functional and ranking data.

Estimation, forecasting, simulation, and portfolio construction for regime-switching models with exogenous variables as in Pelletier (2006) <doi:10.1016/j.jeconom.2005.01.013>.

This package provides a GUI for the orloca package is provided as a Rcmdr plug-in. The package deals with continuos planar location problems.

This package contains functions to create regulatory-style statistical reports. Originally designed to create tables, listings, and figures for the pharmaceutical, biotechnology, and medical device industries, these reports are generalized enough that they could be used in any industry. Generates text, rich-text, PDF, HTML, and Microsoft Word file formats. The package specializes in printing wide and long tables with automatic page wrapping and splitting. Reports can be produced with a minimum of function calls, and without relying on other table packages. The package supports titles, footnotes, page header, page footers, spanning headers, page by variables, and automatic page numbering.