This package provides a toolkit for analytical variance estimation in survey sampling. Apart from the implementation of standard variance estimators, its main feature is to help the sampling expert produce easy-to-use variance estimation "wrappers", where systematic operations (linearization, domain estimation) are handled in a consistent and transparent way.

This package provides basic distribution functions for a generalized logistic distribution proposed by Rathie and Swamee (2006) <https://www.rroij.com/open-access/on-new-generalized-logistic-distributions-and-applicationsbarreto-fhs-mota-jma-and-rathie-pn-.pdf>. It also has an interactive RStudio plot for better guessing dynamically of initial values for ease of included optimization and simulating.

This is a GitHub API wrapper for R. <https://docs.github.com/en/rest> It uses the gh package but has things wrapped up for convenient use cases.

Generates synthetic time series based on various univariate time series models including MAR and ARIMA processes. Kang, Y., Hyndman, R.J., Li, F.(2020) <doi:10.1002/sam.11461>.

Maximum likelihood estimation under relational models, with or without the overall effect.

Run a Gibbs sampler for a multivariate Bayesian sparse group selection model with Dirac, continuous and hierarchical spike prior for detecting pleiotropy on the traits. This package is designed for summary statistics containing estimated regression coefficients and its estimated covariance matrix. The methodology is available from: Baghfalaki, T., Sugier, P. E., Truong, T., Pettitt, A. N., Mengersen, K., & Liquet, B. (2021) <doi:10.1002/sim.8855>.

Computing Global Sensitivity Indices from given data using Optimal Transport, as defined in Borgonovo et al (2024) <doi:10.1287/mnsc.2023.01796>. You provide an input sample, an output sample, decide the algorithm, and compute the indices.

Splits date and time of day components from continuous datetime objects, then plots them using grammar of graphics ('ggplot2'). Plots can also be decorated with solar cycle information (e.g., sunset, sunrise, etc.). This is useful for visualising data that are associated with the solar cycle.

Annotation of ggplot2 plots with arbitrary TikZ code, using absolute data or relative plot coordinates.

Several tests for high dimensional generalized linear models have been proposed recently. In this package, we implemented a new test called adaptive sum of powered score (aSPU) for high dimensional generalized linear models, which is often more powerful than the existing methods in a wide scenarios. We also implemented permutation based version of several existing methods for research purpose. We recommend users use the aSPU test for their real testing problem. You can learn more about the tests implemented in the package via the following papers: 1. Pan, W., Kim, J., Zhang, Y., Shen, X. and Wei, P. (2014) <DOI:10.1534/genetics.114.165035> A powerful and adaptive association test for rare variants, Genetics, 197(4). 2. Guo, B., and Chen, S. X. (2016) <DOI:10.1111/rssb.12152>. Tests for high dimensional generalized linear models. Journal of the Royal Statistical Society: Series B. 3. Goeman, J. J., Van Houwelingen, H. C., and Finos, L. (2011) <DOI:10.1093/biomet/asr016>. Testing against a high-dimensional alternative in the generalized linear model: asymptotic type I error control. Biometrika, 98(2).

This package provides functionality to create customizable volcano plots for visualizing differential gene expression analysis results. The package offers options to highlight genes of interest, adjust significance thresholds, customize colors, and add informative labels. Designed specifically for RNA-seq data analysis workflows.

This is an add on package to GAMLSS. The purpose of this package is to allow users to defined truncated distributions in GAMLSS models. The main function gen.trun() generates truncated version of an existing GAMLSS family distribution.

DNA methylation of 5-methylcytosine (5mC) is the result of a multi-step, enzyme-dependent process. Predicting these sites in-vitro is laborious, time consuming as well as costly. This Gb5mC-Pred package is an in-silico pipeline for predicting DNA sequences containing the 5mC sites. It uses a machine learning approach which uses Stochastic Gradient Boosting approach for prediction of the sequences with 5mC sites. This package has been developed by using the concept of Navarez and Roxas (2022) <doi:10.1109/TCBB.2021.3082184>.

This package performs linear regression with correlated predictors, responses and correlated measurement errors in predictors and responses, correcting for biased caused by these.

It provides a custom ggplot2 geom to add day/night patterns to plots. It visually distinguishes daytime and nighttime periods. It is useful for visualizing data that spans multiple days and for highlighting diurnal patterns.

This package provides functions and methods for: splitting large raster objects into smaller chunks, transferring images from a binary format into raster layers, transferring raster layers into an RData file, calculating the maximum gap (amount of consecutive missing values) of a numeric vector, and fitting harmonic regression models to periodic time series. The homoscedastic harmonic regression model is based on G. Roerink, M. Menenti and W. Verhoef (2000) <doi:10.1080/014311600209814>.

This package provides functions to develop simulated continuous data (e.g., gene expression) from a sigma covariance matrix derived from a graph structure in igraph objects. Intended to extend mvtnorm to take igraph structures rather than sigma matrices as input. This allows the use of simulated data that correctly accounts for pathway relationships and correlations. This allows the use of simulated data that correctly accounts for pathway relationships and correlations. Here we present a versatile statistical framework to simulate correlated gene expression data from biological pathways, by sampling from a multivariate normal distribution derived from a graph structure. This package allows the simulation of biological pathways from a graph structure based on a statistical model of gene expression. For example methods to infer biological pathways and gene regulatory networks from gene expression data can be tested on simulated datasets using this framework. This also allows for pathway structures to be considered as a confounding variable when simulating gene expression data to test the performance of genomic analyses.

Fits unimodal and multimodal gambin distributions to species-abundance distributions from ecological data, as in in Matthews et al. (2014) <DOI:10.1111/ecog.00861>. gambin is short for gamma-binomial'. The main function is fit_abundances(), which estimates the alpha parameter(s) of the gambin distribution using maximum likelihood. Functions are also provided to generate the gambin distribution and for calculating likelihood statistics.

R Interface to C API of GLPK, depends on GLPK Version >= 4.42.

Goodness-of-fit tests for skew-normal, gamma, inverse Gaussian, log-normal, Weibull', Frechet', Gumbel, normal, multivariate normal, Cauchy, Laplace or double exponential, exponential and generalized Pareto distributions. Parameter estimators for gamma, inverse Gaussian and generalized Pareto distributions.

This package provides a not-so-comprehensive list of methods for estimating graphon, a symmetric measurable function, from a single or multiple of observed networks. For a detailed introduction on graphon and popular estimation techniques, see the paper by Orbanz, P. and Roy, D.M.(2014) <doi:10.1109/TPAMI.2014.2334607>. It also contains several auxiliary functions for generating sample networks using various network models and graphons.

Local structure in genomic data often induces dependence between observations taken at different genomic locations. Ignoring this dependence leads to underestimation of the standard error of parameter estimates. This package uses block bootstrapping to estimate asymptotically correct standard errors of parameters from any standard generalised linear model that may be fit by the glm() function.

The American Association Research (AACR) Project Genomics Evidence Neoplasia Information Exchange (GENIE) BioPharma Collaborative represents a multi-year, multi-institution effort to build a pan-cancer repository of linked clinico-genomic data. The genomic and clinical data are provided in multiple releases (separate releases for each cancer cohort with updates following data corrections), which are stored on the data sharing platform Synapse <https://www.synapse.org/>. The genieBPC package provides a seamless way to obtain the data corresponding to each release from Synapse and to prepare datasets for analysis.

Discretize multivariate continuous data using a grid to capture the joint distribution that preserves clusters in original data. It can handle both labeled or unlabeled data. Both published methods (Wang et al 2020) <doi:10.1145/3388440.3412415> and new methods are included. Joint grid discretization can prepare data for model-free inference of association, function, or causality.