Cleaning and standardizing tabular data package, tailored specifically for curating epidemiological data. It streamlines various data cleaning tasks that are typically expected when working with datasets in epidemiology. It returns the processed data in the same format, and generates a comprehensive report detailing the outcomes of each cleaning task.

This package creates a common framework for organizing, naming, and gathering population, age, race, and ethnicity data from the Census Bureau. Accesses the API <https://www.census.gov/data/developers/data-sets.html>. Provides tools for adding information to existing data to line up with Census data.

Parameter estimation of regression models with fixed group effects, when the group variable is missing while group-related variables are available. Parametric and semi-parametric approaches described in Marbac et al. (2020) <arXiv:2012.14159> are implemented.

This package provides functions for calculating clinical significance.

This package provides a compositional mediation model for continuous outcome and binary outcomes to deal with mediators that are compositional data. Lin, Ziqiang et al. (2022) <doi:10.1016/j.jad.2021.12.019>.

Automatically displays graphical visualization for exported data table (permutated results) from Connectivity Map (CMap) (2006) <doi:10.1126/science.1132939>. It allows the representation of the statistics (p-value and enrichment) according to each cell lines in the form of a bubble plot.

The Concordance Test is a non-parametric method for testing whether two o more samples originate from the same distribution. It extends the Kendall Tau correlation coefficient when there are only two groups. For details, see Alcaraz J., Anton-Sanchez L., Monge J.F. (2022) The Concordance Test, an Alternative to Kruskal-Wallis Based on the Kendall-tau Distance: An R Package. The R Journal 14, 26â 53 <doi:10.32614/RJ-2022-039>.

Climate crop zoning based in minimum and maximum air temperature. The data used in the package are from TerraClimate dataset (<https://www.climatologylab.org/terraclimate.html>), but, it have been calibrated with automatic weather stations of National Meteorological Institute of Brazil. The climate crop zoning of this package can be run for all the Brazilian territory.

This package provides methods for powering cluster-randomized trials with two continuous co-primary outcomes using five key design techniques. Includes functions for calculating required sample size and statistical power. For more details on methodology, see Owen et al. (2025) <doi:10.1002/sim.70015>, Yang et al. (2022) <doi:10.1111/biom.13692>, Pocock et al. (1987) <doi:10.2307/2531989>, Vickerstaff et al. (2019) <doi:10.1186/s12874-019-0754-4>, and Li et al. (2020) <doi:10.1111/biom.13212>.

There are 6 novel robust tests for equal correlation. They are all based on logistic regressions. The score statistic U is proportion to difference of two correlations based on different types of correlation in 6 methods. The ST1() is based on Pearson correlation. ST2() improved ST1() by using median absolute deviation. ST3() utilized type M correlation and ST4() used Spearman correlation. ST5() and ST6() used two different ways to combine ST3() and ST4(). We highly recommend ST5() according to the article titled New Statistical Methods for Constructing Robust Differential Correlation Networks to characterize the interactions among microRNAs published in Scientific Reports. Please see the reference: Yu et al. (2019) <doi:10.1038/s41598-019-40167-8>.

Calculate the theoretical value of convertible bonds by given parameters, including B-S theory and Monte Carlo method.

Create data summaries for quality control, extensive reports for exploring data, as well as publication-ready univariate or bivariate tables in several formats (plain text, HTML,LaTeX, PDF, Word or Excel. Create figures to quickly visualise the distribution of your data (boxplots, barplots, normality-plots, etc.). Display statistics (mean, median, frequencies, incidences, etc.). Perform the appropriate tests (t-test, Analysis of variance, Kruskal-Wallis, Fisher, log-rank, ...) depending on the nature of the described variable (normal, non-normal or qualitative). Summarize genetic data (Single Nucleotide Polymorphisms) data displaying Allele Frequencies and performing Hardy-Weinberg Equilibrium tests among other typical statistics and tests for these kind of data.

Matrix-variate covariance estimation via the Kronecker-core decomposition. Computes the Kronecker and core covariance matrices corresponding to an arbitrary covariance matrix, and provides an empirical Bayes covariance estimator that adaptively shrinks towards the space of separable covariance matrices. For details, see Hoff, McCormack and Zhang (2022) <arXiv:2207.12484> "Core Shrinkage Covariance Estimation for Matrix-variate data".

Interact with Condor from R via SSH connection. Files are first uploaded from user machine to submitter machine, and the job is then submitted from the submitter machine to Condor'. Functions are provided to submit, list, and download Condor jobs from R. Condor is an open source high-throughput computing software framework for distributed parallelization of computationally intensive tasks.

Balance sheet and income statement metrics, investment analysis methods, valuation methods, loan amortization schedules, and Capital Asset Pricing Model.

Analysis of network community objects with applications to neuroimaging data. There are two main components to this package. The first is the hierarchical multimodal spinglass (HMS) algorithm, which is a novel community detection algorithm specifically tailored to the unique issues within brain connectivity. The other is a suite of semiparametric kernel machine methods that allow for statistical inference to be performed to test for potential associations between these community structures and an outcome of interest (binary or continuous).

This package provides measures of effect sizes for summarized continuous variables as well as diagnostic accuracy statistics for 2x2 table data. Includes functions for Cohen's d, robust effect size, Cohen's q, partial eta-squared, coefficient of variation, odds ratio, likelihood ratios, sensitivity, specificity, positive and negative predictive values, Youden index, number needed to treat, number needed to diagnose, and predictive summary index.

Calculates equitable overload compensation for college instructors based on institutional policies, enrollment thresholds, and regular teaching load limits. Compensation is awarded only for credit hours that exceed the regular load and meet minimum enrollment criteria. When enrollment is below a specified threshold, pay is prorated accordingly. The package prioritizes compensation from high-enrollment courses, or optionally from low-enrollment courses for fairness, depending on user-defined strategy. Includes tools for flexible policy settings, instructor filtering, and produces clean, audit-ready summary tables suitable for payroll and administrative reporting.

This package provides a basic implementation of the change in mean detection method outlined in: Taylor, Wayne A. (2000) <https://variation.com/wp-content/uploads/change-point-analyzer/change-point-analysis-a-powerful-new-tool-for-detecting-changes.pdf>. The package recursively uses the mean-squared error change point calculation to identify candidate change points. The candidate change points are then re-estimated and Taylor's backwards elimination process is then employed to come up with a final set of change points. Many of the underlying functions are written in C++ for improved performance.

Chromosome files in the Fasta format usually contain large sequences like human genome. Sometimes users have to split these chromosomes into different files according to their chromosome number. The chromseq can help to handle this. So the selected chromosome sequence can be used for downstream analysis like motif finding. Howard Y. Chang(2019) <doi:10.1038/s41587-019-0206-z>.

Several nonparametric estimators of autocovariance functions. Procedures for constructing their confidence regions by using bootstrap techniques. Methods to correct autocovariance estimators and several tools for analysing and comparing them. Supplementary functions, including kernel computations and discrete cosine Fourier transforms. For more details see Bilchouris and Olenko (2025) <doi:10.17713/ajs.v54i1.1975>.

This package provides functions to carry out the most important crystallographic calculations for crystal structures made of 1d Gaussian-shaped atoms, especially useful for methods development. Main reference: E. Smith, G. Evans, J. Foadi (2017) <doi:10.1088/1361-6404/aa8188>.

To optimize clinical trial designs and data analysis methods consistently through trial simulation, we need to simulate multivariate mixed-type virtual patient data independent of designs and analysis methods under evaluation. To make the outcome of optimization more realistic, relevant empirical patient level data should be utilized when itâ s available. However, a few problems arise in simulating trials based on small empirical data, where the underlying marginal distributions and their dependence structure cannot be understood or verified thoroughly due to the limited sample size. To resolve this issue, we use the copula invariance property, which can generate the joint distribution without making a strong parametric assumption. The function copula.sim can generate virtual patient data with optional data validation methods that are based on energy distance and ball divergence measurement. The function compare.copula.sim can conduct comparison of marginal mean and covariance of simulated data. To simulate patient-level data from a hypothetical treatment arm that would perform differently from the observed data, the function new.arm.copula.sim can be used to generate new multivariate data with the same dependence structure of the original data but with a shifted mean vector.

Convert text into synthesized speech and get a list of supported voices for a region. Microsoft's Cognitive Services Text to Speech REST API <https://learn.microsoft.com/en-us/azure/cognitive-services/speech-service/rest-text-to-speech?tabs=streaming> supports neural text to speech voices, which support specific languages and dialects that are identified by locale.