The main attribute of PopVar is the prediction of genetic variance in bi-parental populations, from which the package derives its name. PopVar contains a set of functions that use phenotypic and genotypic data from a set of candidate parents to 1) predict the mean, genetic variance, and superior progeny value of all, or a defined set of pairwise bi-parental crosses, and 2) perform cross-validation to estimate genome-wide prediction accuracy of multiple statistical models. More details are available in Mohammadi, Tiede, and Smith (2015, <doi:10.2135/cropsci2015.01.0030>). A dataset think_barley.rda is included for reference and examples.

Allow to run pylint on Python files with a R command or a RStudio addin. The report appears in the RStudio viewer pane as a formatted HTML file.

This package implements sparse regression with paired covariates (<doi:10.1007/s11634-019-00375-6>). The paired lasso is designed for settings where each covariate in one set forms a pair with a covariate in the other set (one-to-one correspondence). For the optional correlation shrinkage, install ashr (<https://github.com/stephens999/ashr>) and CorShrink (<https://github.com/kkdey/CorShrink>) from GitHub (see README).

Given a sample with additive measurement error, the package estimates the deconvolution density - that is, the density of the underlying distribution of the sample without measurement error. The method maximises the log-likelihood of the estimated density, plus a quadratic smoothness penalty. The distribution of the measurement error can be either a known family, or can be estimated from a "pure error" sample. For known error distributions, the package supports Normal, Laplace or Beta distributed error. For unknown error distribution, a pure error sample independent from the data is used.

Streamline the creation of Docker images with R packages and dependencies embedded. The pracpac package provides a usethis'-like interface to creating Dockerfiles with dependencies managed by renv'. The pracpac functionality is described in Nagraj and Turner (2023) <doi:10.48550/arXiv.2303.07876>.

This package provides a clinical decision support system for sub-symptom threshold aerobic exercise (SSTAE) prescription in adolescents with persistent post-concussion symptoms (PPCS). Implements an evidence-based protocol derived from a systematic review of seven studies (Li, 2026; <doi:10.17605/osf.io/kvuf6>), encoding safety screening, Buffalo Concussion Treadmill Test (BCTT)-guided heart rate prescription, session-level progress tracking, and evidence disclosure using the Grading of Recommendations, Assessment, Development and Evaluation (GRADE) framework into an open-source tool for athletic trainers and clinicians. Designed to support implementation in resource-limited settings where BCTT equipment may be unavailable. GRADE certainty of evidence: LOW. For clinician use only; not a substitute for clinical judgement.

Priority-ElasticNet extends the Priority-LASSO method (Klau et al. (2018) <doi:10.1186/s12859-018-2344-6>) by incorporating the ElasticNet penalty, allowing for both L1 and L2 regularization. This approach fits successive ElasticNet models for several blocks of (omics) data with different priorities, using the predicted values from each block as an offset for the subsequent block. It also offers robust options to handle block-wise missingness in multi-omics data, improving the flexibility and applicability of the model in the presence of incomplete datasets.

This package provides an object type and associated tools for storing and wrangling panel data. Implements several methods for creating regression models that take advantage of the unique aspects of panel data. Among other capabilities, automates the "within-between" (also known as "between-within" and "hybrid") panel regression specification that combines the desirable aspects of both fixed effects and random effects econometric models and fits them as multilevel models (Allison, 2009 <doi:10.4135/9781412993869.d33>; Bell & Jones, 2015 <doi:10.1017/psrm.2014.7>). These models can also be estimated via generalized estimating equations (GEE; McNeish, 2019 <doi:10.1080/00273171.2019.1602504>) and Bayesian estimation is (optionally) supported via Stan'. Supports estimation of asymmetric effects models via first differences (Allison, 2019 <doi:10.1177/2378023119826441>) as well as a generalized linear model extension thereof using GEE.

This package provides a collection of process capability index functions, such as C_p(), C_pk(), C_pm(), and others, along with metadata about each, like LaTeX equations and R expressions. Its primary purpose is to form a foundation for other quality control packages to build on top of, by providing basic resources and functions. The indices belong to the field of statistical quality control, and quantify the degree to which a manufacturing process is able to create items that adhere to a certain standard of quality. For details see Montgomery, D. C. (2019, ISBN:978-1-119-39930-8).

This package provides a novel tool for generating a piecewise constant estimation list of increasingly complex predictors based on an intensive and comprehensive search over the entire covariate space.

This package provides a suite of non-parametric, visual tools for assessing differences in data structures for two datasets that contain different observations of the same variables. These tools are all based on Principal Component Analysis (PCA) and thus effectively address differences in the structures of the covariance matrices of the two datasets. The PCASDC tools consist of easy-to-use, intuitive plots that each focus on different aspects of the PCA decompositions. The cumulative eigenvalue (CE) plot describes differences in the variance components (eigenvalues) of the deconstructed covariance matrices. The angle plot presents the information loss when moving from the PCA decomposition of one dataset to the PCA decomposition of the other. The chroma plot describes the loading patterns of the two datasets, thereby presenting the relative weighting and importance of the variables from the original dataset.

Probabilistic factor analysis for spatially-aware dimension reduction across multi-section spatial transcriptomics data with millions of spatial locations. More details can be referred to Wei Liu, et al. (2023) <doi:10.1101/2023.07.11.548486>.

Bayesian estimation and analysis methods for Probit Unfolding Models (PUMs), a novel class of scaling models designed for binary preference data. These models allow for both monotonic and non-monotonic response functions. The package supports Bayesian inference for both static and dynamic PUMs using Markov chain Monte Carlo (MCMC) algorithms with minimal or no tuning. Key functionalities include posterior sampling, hyperparameter selection, data preprocessing, model fit evaluation, and visualization. The methods are particularly suited to analyzing voting data, such as from the U.S. Congress or Supreme Court, but can also be applied in other contexts where non-monotonic responses are expected. For methodological details, see Shi et al. (2025) <doi:10.48550/arXiv.2504.00423>.

This package implements the estimator of Tugan (2021) <doi:10.1093/ectj/utaa021> for panel vector autoregression (VAR) models with interactive fixed effects. Provides joint estimation of VAR coefficients, latent common factors, and factor loadings via an iterative algorithm that alternates between principal component estimation of the factors and least squares estimation of the VAR coefficients, following the approach of Bai (2009) <doi:10.3982/ECTA6135>. Supports impulse response functions under recursive (Cholesky) identification, parametric confidence bands from the joint asymptotic distribution of the estimator (Theorem 2.3), and a classical residual bootstrap for robustness checks.

This package provides a semi-parametric estimation method for the Cox model with left-truncated data using augmented information from the marginal of truncation times.

Computes the Patient-Reported Outcomes (PROs) Joint Contrast (PJC), a residual-based summary that captures information left over after accounting for the clinical Disease Activity index for Psoriatic Arthritis (cDAPSA). PROs (pain and patient global assessment) and joint counts (swollen and tender) are standardized, then each component is adjusted for standardized cDAPSA using natural spline coefficients that were derived from previously published models. The resulting residuals are standardized and combined using fixed principal component loadings, to yield a continuous PJC score and quartile groupings. This package provides a calculator for applying those published coefficients to new datasets; it does not itself estimate spline models or principal components.

Predicts the most common race of a surname and based on U.S. Census data, and the most common first named based on U.S. Social Security Administration data.

Fast tools for fitting sparse generalized linear models with convex penalties (lasso) and concave penalties (smoothly clipped absolute deviation and minimax concave penalty). Computation uses multi-stage convex relaxation and pathwise coordinate optimization with warm starts, active-set updates, and screening rules. Core solvers are implemented in C++, and coefficient paths are stored as sparse matrices for memory efficiency.

Implementation of an oligonucleotide primer and probe design algorithm using a linearly scaling approximation of set coverage. A detailed description available at Smolander and Tamminen, 2021; <doi:10.1101/2021.09.06.459073>.

Reproducible, programmatic retrieval of survey datasets from the Pew Research Center.

This package implements the Phylogeny-Guided Microbiome OTU-Specific Association Test method, which boosts the testing power by adaptively borrowing information from phylogenetically close OTUs (operational taxonomic units) of the target OTU. This method is built on a kernel machine regression framework and allows for flexible modeling of complex microbiome effects, adjustments for covariates, and can accommodate both continuous and binary outcomes.

Conduct power analyses and inference of marginal effects. Uses plug-in estimation and influence functions to perform robust inference, optionally leveraging historical data to increase precision with prognostic covariate adjustment. The methods are described in Højbjerre-Frandsen et al. (2025) <doi:10.48550/arXiv.2503.22284>.

Read, process, fit, and analyze photosynthetic gas exchange measurements. Documentation is provided by several vignettes; also see Lochocki, Salesse-Smith, & McGrath (2025) <doi:10.1111/pce.15501>.

This package provides a central decision in a parametric regression is how to specify the relation between an dependent variable and each explanatory variable. This package provides a semi-parametric tool for comparing different transformations of an explanatory variables in a parametric regression. The functions is relevant in a situation, where you would use a box-cox or Box-Tidwell transformations. In contrast to the classic power-transformations, the methods in this package allows for theoretical driven user input and the possibility to compare with a non-parametric transformation.