Calculate the operating characteristics of the Bayesian Optimal Interval with Back Filling Design for dose escalation in early-phase oncology trials.

Bayesian model and associated tools for generating estimates of total naloxone kit numbers distributed and used from naloxone kit orders data. Provides functions for generating simulated data of naloxone kit use and functions for generating samples from the posterior.

This package performs general Bayesian estimation method of linearâ bilinear models for genotype à environment interaction. The method is explained in Perez-Elizalde, S., Jarquin, D., and Crossa, J. (2011) (<doi:10.1007/s13253-011-0063-9>).

The method models RNA-seq reads using a mixture of 3 beta-binomial distributions to generate posterior probabilities for genotyping bi-allelic single nucleotide polymorphisms. Elena Vigorito, Anne Barton, Costantino Pitzalis, Myles J. Lewis and Chris Wallace (2023) <doi:10.1093/bioinformatics/btad393> "BBmix: a Bayesian beta-binomial mixture model for accurate genotyping from RNA-sequencing.".

Implementation of a statistical approach for estimating the joint health effects of multiple concurrent exposures, as described in Bobb et al (2015) <doi:10.1093/biostatistics/kxu058>.

Estimate fish length-at-age models using MCMC analysis with rstan models. This package allows a multimodel approach to growth fitting to be applied to length-at-age data and is supported by further analyses to determine model selection and result presentation. The core methods of this package are presented in Smart and Grammer (2021) "Modernising fish and shark growth curves with Bayesian length-at-age models". PLOS ONE 16(2): e0246734 <doi:10.1371/journal.pone.0246734>.

This package provides tools for sampling from the PolyaGamma distribution based on Polson, Scott, and Windle (2013) <doi:10.1080/01621459.2013.829001>. Useful for logistic regression.

Allows Bayesian borrowing from a historical dataset for time-to- event data. A flexible baseline hazard function is achieved via a piecewise exponential likelihood with time varying split points and smoothing prior on the historic baseline hazards. The method is described in Scott and Lewin (2024) <doi:10.48550/arXiv.2401.06082>, and the software paper is in Axillus et al. (2024) <doi:10.48550/arXiv.2408.04327>.

This package implements state-of-the-art algorithms for the Bayesian analysis of Structural Vector Autoregressions (SVARs) identified by sign, zero, and narrative restrictions. The core model is based on a flexible Vector Autoregression with estimated hyper-parameters of the Minnesota prior and the dummy observation priors as in Giannone, Lenza, Primiceri (2015) <doi:10.1162/REST_a_00483>. The sign restrictions are implemented employing the methods proposed by Rubio-Ramà rez, Waggoner & Zha (2010) <doi:10.1111/j.1467-937X.2009.00578.x>, while identification through sign and zero restrictions follows the approach developed by Arias, Rubio-Ramà rez, & Waggoner (2018) <doi:10.3982/ECTA14468>. Furthermore, our tool provides algorithms for identification via sign and narrative restrictions, in line with the methods introduced by Antolà n-Dà az and Rubio-Ramà rez (2018) <doi:10.1257/aer.20161852>. Users can also estimate a model with sign, zero, and narrative restrictions imposed at once. The package facilitates predictive and structural analyses using impulse responses, forecast error variance and historical decompositions, forecasting and conditional forecasting, as well as analyses of structural shocks and fitted values. All this is complemented by colourful plots, user-friendly summary functions, and comprehensive documentation including the vignette by Wang & Woźniak (2024) <doi:10.48550/arXiv.2501.16711>. The bsvarSIGNs package is aligned regarding objects, workflows, and code structure with the R package bsvars by Woźniak (2024) <doi:10.32614/CRAN.package.bsvars>, and they constitute an integrated toolset. It was granted the Di Cook Open-Source Statistical Software Award by the Statistical Society of Australia in 2024.

The card game War is simple in its rules but can be lengthy. In another domain, the nonparametric bootstrap test with pooled resampling (nbpr) methods, as outlined in Dwivedi, Mallawaarachchi, and Alvarado (2017) <doi:10.1002/sim.7263>, is optimal for comparing paired or unpaired means in non-normal data, especially for small sample size studies. However, many researchers are unfamiliar with these methods. The bootwar package bridges this gap by enabling users to grasp the concepts of nbpr via Boot War, a variation of the card game War designed for small samples. The package provides functions like score_keeper() and play_round() to streamline gameplay and scoring. Once a predetermined number of rounds concludes, users can employ the analyze_game() function to derive game results. This function leverages the npboottprm package's nonparboot() to report nbpr results and, for comparative analysis, also reports results from the stats package's t.test() function. Additionally, bootwar features an interactive shiny web application, bootwar(). This offers a user-centric interface to experience Boot War, enhancing understanding of nbpr methods across various distributions, sample sizes, number of bootstrap resamples, and confidence intervals.

Computes Bayesian A- and D-optimal block designs under the linear mixed effects model settings using block/array exchange algorithm of Debusho, Gemechu and Haines (2018) <doi:10.1080/03610918.2018.1429617> and Gemechu, Debusho and Haines (2025) <doi:10.5539/ijsp.v14n1p50> where the interest is in a comparison of all possible elementary treatment contrasts. The package also provides an optional method of using the graphical user interface (GUI) R package tcltk to ensure that it is user friendly.

Implementation of the bootstrapping approach for the estimation of clustering stability and its application in estimating the number of clusters, as introduced by Yu et al (2016)<doi:10.1142/9789814749411_0007>. Implementation of the non-parametric bootstrap approach to assessing the stability of module detection in a graph, the extension for the selection of a parameter set that defines a graph from data in a way that optimizes stability and the corresponding visualization functions, as introduced by Tian et al (2021) <doi:10.1002/sam.11495>. Implemented out-of-bag stability estimation function and k-select Smin-based k-selection function as introduced by Liu et al (2022) <doi:10.1002/sam.11593>. Implemented ensemble clustering method based-on k-means clustering method, spectral clustering method and hierarchical clustering method.

Comprehensive Business Process Analysis toolkit. Creates S3-class for event log objects, and related handler functions. Imports related packages for filtering event data, computation of descriptive statistics, handling of Petri Net objects and visualization of process maps. See also packages edeaR','processmapR', eventdataR and processmonitR'.

Visualizing the types and distribution of elements within bio-sequences. At the same time, We have developed a geom layer, geom_rrect(), that can generate rounded rectangles. No external references are used in the development of this package.

Fits latent threshold model for simulated data and describes how to adjust model using real data. Implements algorithm proposed by Nakajima and West (2013) <doi:10.1080/07350015.2012.747847>. This package has a function to generate data, a function to configure priors and a function to fit the model. Examples may be checked inside the demonstration files.

This package provides tools for downloading historical financial data from the www.belex.rs.

Many clustering methods have been proposed, but most of them cannot work for longitudinal gene expression data. BClustLonG is a package that allows us to perform clustering analysis for longitudinal gene expression data. It adopts a linear-mixed effects framework to model the trajectory of genes over time, while clustering is jointly conducted based on the regression coefficients obtained from all genes. To account for the correlations among genes and alleviate the high dimensionality challenges, factor analysis models are adopted for the regression coefficients. The Dirichlet process prior distribution is utilized for the means of the regression coefficients to induce clustering. This package allows users to specify which variables to use for clustering (intercepts or slopes or both) and whether a factor analysis model is desired. More details about this method can be found in Jiehuan Sun, et al. (2017) <doi:10.1002/sim.7374>.

This package provides a tool to perform all different statistical tests and calculations needed by Biological dosimetry Laboratories. Detailed documentation is available in <https://biodosetools-team.github.io/documentation/>.

This package provides tools to process the information obtained from experiments conducted in the Barnes Maze. These tools enable the detection of trajectories generated by subjects during trials, as well as the acquisition of precise coordinates and relevant statistical data regarding the results. Through this approach, it aims to facilitate the analysis and interpretation of observed behaviors, thereby contributing to a deeper understanding of learning and memory processes in such experiments.

An R interface to the Stark-Parker implementation of an algorithm for bounded-variable least squares.

Various supervised and unsupervised binning tools including using entropy, recursive partition methods and clustering.

This is an implementation of BART:Bayesian Additive Regression Trees, by Chipman, George, McCulloch (2010).

This package implements functions that calculate upper prediction bounds on the false discovery proportion (FDP) in the list of discoveries returned by competition-based setups, implementing Ebadi et al. (2022) <arXiv:2302.11837>. Such setups include target-decoy competition (TDC) in computational mass spectrometry and the knockoff construction in linear regression (note this package typically uses the terminology of TDC). Included is the standardized (TDC-SB) and uniform (TDC-UB) bound on TDC's FDP, and the simultaneous standardized and uniform bands. Requires pre-computed Monte Carlo statistics available at <https://github.com/uni-Arya/fdpbandsdata>. This data can be downloaded by running the command devtools::install_github("uni-Arya/fdpbandsdata") in R and restarting R after installation. The size of this data is roughly 81Mb.

Included here are babel routines for identifying unusual ribosome protected fragment counts given mRNA counts.