This package implements a procedure to automatically generate 2D masks for clusters on dimensional reduction plots from methods like t-SNE (t-distributed stochastic neighbor embedding) or UMAP (uniform manifold approximation and projection), with a focus on single-cell RNA-sequencing data.

Fits Semiparametric Promotion Time Cure Models, taking into account (using a corrected score approach or the SIMEX algorithm) or not the measurement error in the covariates, using a backfitting approach to maximize the likelihood.

Simultaneous multiple outcomes prediction based on revised stacking algorithms, which enables the integration of information from predictions of individual models. An implementation of methodologies proposed in our paper: Li Xing, Mary L Lesperance, Xuekui Zhang. (2019) Bioinformatics, "Simultaneous prediction of multiple outcomes using revised stacking algorithms" <doi:10.1093/bioinformatics/btz531>.

This package provides methods for modeling moderator variables in cross-sectional, temporal, and multi-level networks. Includes model selection techniques and a variety of plotting functions. Implements the methods described by Swanson (2020) <https://www.proquest.com/openview/d151ab6b93ad47e3f0d5e59d7b6fd3d3>.

Describes spatial patterns of categorical raster data for any defined regular and irregular areas. Patterns are described quantitatively using built-in signatures based on co-occurrence matrices but also allows for any user-defined functions. It enables spatial analysis such as search, change detection, and clustering to be performed on spatial patterns (Nowosad (2021) <doi:10.1007/s10980-020-01135-0>).

Multiplicative AR(1) with Seasonal is a stochastic process model built on top of AR(1). The package provides the following procedures for MAR(1)S processes: fit, compose, decompose, advanced simulate and predict.

This system allows one to model a multi-variate, multi-response problem with interaction effects. It combines the usual squared error loss for the multi-response problem with some penalty terms to encourage responses that correlate to form groups and also allow for modeling main and interaction effects that exit within the covariates. The optimization method employed is the Alternating Direction Method of Multipliers (ADMM). The implementation is based on the methodology presented on Quachie Asenso, T., & Zucknick, M. (2023) <doi:10.48550/arXiv.2303.11155>.

This package provides a test of multivariate normality of an unknown sample that does not require estimation of the nuisance parameters, the mean and covariance matrix. Rather, a sequence of transformations removes these nuisance parameters and results in a set of sample matrices that are positive definite. These matrices are uniformly distributed on the space of positive definite matrices in the unit hyper-rectangle if and only if the original data is multivariate normal (Fairweather, 1973, Doctoral dissertation, University of Washington). The package performs a goodness of fit test of this hypothesis. In addition to the test, functions in the package give visualizations of the support region of positive definite matrices for bivariate samples.

The maybe type represents the possibility of some value or nothing. It is often used instead of throwing an error or returning `NULL`. The advantage of using a maybe type over `NULL` is that it is both composable and requires the developer to explicitly acknowledge the potential absence of a value, helping to avoid the existence of unexpected behaviour.

For single tensor data, any matrix factorization method can be specified the matricised tensor in each dimension by Multi-way Component Analysis (MWCA). An originally extended MWCA is also implemented to specify and decompose multiple matrices and tensors simultaneously (CoupledMWCA). See the reference section of GitHub README.md <https://github.com/rikenbit/mwTensor>, for details of the methods.

This package provides a comprehensive graphical user interface for analysis of Affymetrix, Agilent, Illumina, Nimblegen and other microarray data. It can perform miscellaneous tasks such as gene set enrichment and test analyses, identifying gene symbols and building co-expression network. It can also estimate sample size for atleast two-fold expression change. The current version is its slenderized form for compatable and flexible implementation.

Model fitting, sampling and visualization for the (Hidden) Markov Random Field model with pairwise interactions and general interaction structure from Freguglia, Garcia & Bicas (2020) <doi:10.1002/env.2613>, which has many popular models used in 2-dimensional lattices as particular cases, like the Ising Model and Potts Model. A complete manuscript describing the package is available in Freguglia & Garcia (2022) <doi:10.18637/jss.v101.i08>.

Play and record games of minesweeper using a graphics device that supports event handling. Replay recorded games and save GIF animations of them. Based on classic minesweeper as detailed by Crow P. (1997) <https://minesweepergame.com/math/a-mathematical-introduction-to-the-game-of-minesweeper-1997.pdf>.

This package performs treatment assignment for (field) experiments considering available, possibly multivariate and continuous, information (covariates, observable characteristics), that is: forms balanced treatment groups, according to the minMSE-method as proposed by Schneider and Schlather (2017) <DOI:10419/161931>.

Counting process structure is fundamental to model time varying covariates. This package restructures dataframes in the counting process format for one or more variables. F. W. Dekker, et al. (2008) <doi:10.1038/ki.2008.328>.

This package provides a set of tools for testing networks. It includes functions for univariate and multivariate conditional uniform graph and quadratic assignment procedure testing, and network regression. The package is a complement to Multimodal Political Networks (2021, ISBN:9781108985000), and includes various datasets used in the book. Built on the manynet package, all functions operate with matrices, edge lists, and igraph', network', and tidygraph objects, and on one-mode and two-mode (bipartite) networks.

This package provides a minimal library specifically designed to make the estimation of Machine Learning (ML) techniques as easy and accessible as possible, particularly within the framework of the Knowledge Discovery in Databases (KDD) process in data mining. The package provides essential tools to structure and execute each stage of a predictive or classification modeling workflow, aligning closely with the fundamental steps of the KDD methodology, from data selection and preparation, through model building and tuning, to the interpretation and evaluation of results using Sensitivity Analysis. The MLwrap workflow is organized into four core steps; preprocessing(), build_model(), fine_tuning(), and sensitivity_analysis(). It also includes global and pairwise interaction analysis based on Friedmanâ s H-statistic to support a more detailed interpretation of complex feature relationships.These steps correspond, respectively, to data preparation and transformation, model construction, hyperparameter optimization, and sensitivity analysis. The user can access comprehensive model evaluation results including fit assessment metrics, plots, predictions, and performance diagnostics for ML models implemented through Neural Networks', Random Forest', XGBoost (Extreme Gradient Boosting), and Support Vector Machines (SVM) algorithms. By streamlining these phases, MLwrap aims to simplify the implementation of ML techniques, allowing analysts and data scientists to focus on extracting actionable insights and meaningful patterns from large datasets, in line with the objectives of the KDD process.

User-friendly general package providing standard methods for meta-analysis and supporting Schwarzer, Carpenter, and Rücker <DOI:10.1007/978-3-319-21416-0>, "Meta-Analysis with R" (2015): - common effect and random effects meta-analysis; - several plots (forest, funnel, Galbraith / radial, L'Abbe, Baujat, bubble); - three-level meta-analysis model; - generalised linear mixed model; - logistic regression with penalised likelihood for rare events; - Hartung-Knapp method for random effects model; - Kenward-Roger method for random effects model; - prediction interval; - statistical tests for funnel plot asymmetry; - trim-and-fill method to evaluate bias in meta-analysis; - meta-regression; - cumulative meta-analysis and leave-one-out meta-analysis; - import data from RevMan 5'; - produce forest plot summarising several (subgroup) meta-analyses.

Fit and simulate mixtures of von Mises-Fisher distributions.

This toolkit allows performing continuous-time microsimulation for a wide range of life science (demography, social sciences, epidemiology) applications. Individual life-courses are specified by a continuous-time multi-state model as described in Zinn (2014) <doi:10.34196/IJM.00105>.

Selects matched samples of the original treated and control groups with similar covariate distributions -- can be used to match exactly on covariates, to match on propensity scores, or perform a variety of other matching procedures. The package also implements a series of recommendations offered in Ho, Imai, King, and Stuart (2007) <DOI:10.1093/pan/mpl013>. (The gurobi package, which is not on CRAN, is optional and comes with an installation of the Gurobi Optimizer, available at <https://www.gurobi.com>.).

Two novel matching-based methods for estimating group average treatment effects (GATEs). The match_y1y0() and match_y1y0_bc() functions are used for imputing the potential outcomes based on matching and bias-corrected matching techniques, respectively. The EstGATE() function is employed to estimate the GATE after imputing the potential outcomes.

Extend the functionality of the mclust package for Gaussian finite mixture modeling by including: density estimation for data with bounded support (Scrucca, 2019 <doi:10.1002/bimj.201800174>); modal clustering using MEM (Modal EM) algorithm for Gaussian mixtures (Scrucca, 2021 <doi:10.1002/sam.11527>); entropy estimation via Gaussian mixture modeling (Robin & Scrucca, 2023 <doi:10.1016/j.csda.2022.107582>); Gaussian mixtures modeling of financial log-returns (Scrucca, 2024 <doi:10.3390/e26110907>).

This package implements Multi-Group Sparse Discriminant Analysis proposal of I.Gaynanova, J.Booth and M.Wells (2016), Simultaneous sparse estimation of canonical vectors in the p>>N setting, JASA <doi:10.1080/01621459.2015.1034318>.