This package implements functions that calculate upper prediction bounds on the false discovery proportion (FDP) in the list of discoveries returned by competition-based setups, implementing Ebadi et al. (2022) <arXiv:2302.11837>. Such setups include target-decoy competition (TDC) in computational mass spectrometry and the knockoff construction in linear regression (note this package typically uses the terminology of TDC). Included is the standardized (TDC-SB) and uniform (TDC-UB) bound on TDC's FDP, and the simultaneous standardized and uniform bands. Requires pre-computed Monte Carlo statistics available at <https://github.com/uni-Arya/fdpbandsdata>. This data can be downloaded by running the command devtools::install_github("uni-Arya/fdpbandsdata") in R and restarting R after installation. The size of this data is roughly 81Mb.

The function estimates the hazard function non parametrically from a survival object (possibly adjusted for covariates). The smoothed estimate is based on B-splines from the perspective of generalized linear mixed models. Left truncated and right censoring data are allowed. The package is based on the work in Rebora P (2014) <doi:10.32614/RJ-2014-028>.

It brings together several aspects of biodiversity data-cleaning in one place. bdc is organized in thematic modules related to different biodiversity dimensions, including 1) Merge datasets: standardization and integration of different datasets; 2) pre-filter: flagging and removal of invalid or non-interpretable information, followed by data amendments; 3) taxonomy: cleaning, parsing, and harmonization of scientific names from several taxonomic groups against taxonomic databases locally stored through the application of exact and partial matching algorithms; 4) space: flagging of erroneous, suspect, and low-precision geographic coordinates; and 5) time: flagging and, whenever possible, correction of inconsistent collection date. In addition, it contains features to visualize, document, and report data quality â which is essential for making data quality assessment transparent and reproducible. The reference for the methodology is Ribeiro and colleagues (2022) <doi:10.1111/2041-210X.13868>.

Simulating the sequential multi-arm multi-stage or platform trial with Bayesian approach using the rstan package, which provides the R interface for the Stan. This package supports fixed ratio and Bayesian adaptive randomization approaches for randomization. Additionally, it allows for the study of time trend problems in platform trials. There are demos available for a multi-arm multi-stage trial with two different null scenarios, as well as for Bayesian trial cutoff screening. The Bayesian adaptive randomisation approaches are described in: Trippa et al. (2012) <doi:10.1200/JCO.2011.39.8420> and Wathen et al. (2017) <doi:10.1177/1740774517692302>. The randomisation algorithm is described in: Zhao W <doi:10.1016/j.cct.2015.06.008>. The analysis methods of time trend effect in platform trial are described in: Saville et al. (2022) <doi:10.1177/17407745221112013> and Bofill Roig et al. (2022) <doi:10.1186/s12874-022-01683-w>.

Package BHMSMAfMRI performs Bayesian hierarchical multi-subject multiscale analysis of fMRI data as described in Sanyal & Ferreira (2012) <DOI:10.1016/j.neuroimage.2012.08.041>, or other multiscale data, using wavelet-based prior that borrows strength across subjects and provides posterior smoothed images of the effect sizes and samples from the posterior distribution.

Survey systems and other third-party data sources commonly use non-standard representations of logical values when it comes to qualitative data - "Yes", "No" and "N/A", say. batman is a package designed to seamlessly convert these into logicals. It is highly localised, and contains equivalents to boolean values in languages including German, French, Spanish, Italian, Turkish, Chinese and Polish.

This package provides a continuous date scale, omitting weekends and holidays.

Fits boundary line models to datasets as proposed by Webb (1972) <doi:10.1080/00221589.1972.11514472> and makes statistical inferences about their parameters. Provides additional tools for testing datasets for evidence of boundary presence and selecting initial starting values for model optimization prior to fitting the boundary line models. It also includes tools for conducting post-hoc analyses such as predicting boundary values and identifying the most limiting factor (Miti, Milne, Giller, Lark (2024) <doi:10.1016/j.fcr.2024.109365>). This ensures a comprehensive analysis for datasets that exhibit upper boundary structures.

This package provides methods for the binarization and trinarization of one-dimensional data and some visualization functions.

This package provides tools for Bayesian basket trial design and analysis using a novel three-component local power prior framework with global borrowing control, pairwise similarity assessment and a borrowing threshold. Supports simulation-based evaluation of operating characteristics and comparison with other methods. Applicable to both equal and unequal sample size settings in early-phase oncology trials. For more details see Zhou et al. (2023) <doi:10.48550/arXiv.2312.15352>.

This package provides a set of functions for doing analysis of A/B split test data and web metrics in general.

This package provides tools for sampling from the PolyaGamma distribution based on Polson, Scott, and Windle (2013) <doi:10.1080/01621459.2013.829001>. Useful for logistic regression.

This package provides a computational tool to describe patterns in black and white images from natural structures. bwimage implemented functions for exceptionally broad subject. For instance, bwimage provide examples that range from calculation of canopy openness, description of patterns in vertical vegetation structure, to patterns in bird nest structure.

Large panel data sets are often subject to common trends. However, it can be difficult to determine the exact number of these common factors and analyse their properties. The package implements the Barigozzi and Trapani (2022) <doi:10.1080/07350015.2021.1901719> test, which not only provides an efficient way of estimating the number of common factors in large nonstationary panel data sets, but also gives further insights on factor classes. The routine identifies the existence of (i) a factor subject to a linear trend, (ii) the number of zero-mean I(1) and (iii) zero-mean I(0) factors. Furthermore, the package includes the Integrated Panel Criteria by Bai (2004) <doi:10.1016/j.jeconom.2003.10.022> that provide a complementary measure for the number of factors.

Fast and accurate calculation of Blaker's binomial and Poisson confidence limits (and some related stuff).

This package provides functions for the evaluation of basket trial designs with binary endpoints. Operating characteristics of a basket trial design are assessed by simulating trial data according to scenarios, analyzing the data with Bayesian hierarchical models (BHMs), and assessing decision probabilities on stratum and trial-level based on Go / No-go decision making. The package is build for high flexibility regarding decision rules, number of interim analyses, number of strata, and recruitment. The BHMs proposed by Berry et al. (2013) <doi:10.1177/1740774513497539> and Neuenschwander et al. (2016) <doi:10.1002/pst.1730>, as well as a model that combines both approaches are implemented. Functions are provided to implement Bayesian decision rules as for example proposed by Fisch et al. (2015) <doi:10.1177/2168479014533970>. In addition, posterior point estimates (mean/median) and credible intervals for response rates and some model parameters can be calculated. For simulated trial data, bias and mean squared errors of posterior point estimates for response rates can be provided.

Highly efficient functions for estimating various rank (centrality) measures of nodes in bipartite graphs (two-mode networks). Includes methods for estimating HITS, CoHITS, BGRM, and BiRank with implementation primarily inspired by He et al. (2016) <doi:10.1109/TKDE.2016.2611584>. Also provides easy-to-use tools for efficiently estimating PageRank in one-mode graphs, incorporating or removing edge-weights during rank estimation, projecting two-mode graphs to one-mode, and for converting edgelists and matrices to sparseMatrix format. Best of all, the package's rank estimators can work directly with common formats of network data including edgelists (class data.frame, data.table, or tbl_df) and adjacency matrices (class matrix or dgCMatrix).

Implementations of Bayesian parametric, nonparametric and semiparametric procedures for univariate and multivariate time series. The package is based on the methods presented in C. Kirch et al (2018) <doi:10.1214/18-BA1126>, A. Meier (2018) <https://opendata.uni-halle.de//handle/1981185920/13470> and Y. Tang et al (2025) <doi:10.1080/01621459.2025.2594191>. It was supported by DFG grants KI 1443/3-1 and KI 1443/3-2.

Computes Bayesian A- and D-optimal block designs under the linear mixed effects model settings using block/array exchange algorithm of Debusho, Gemechu and Haines (2018) <doi:10.1080/03610918.2018.1429617> and Gemechu, Debusho and Haines (2025) <doi:10.5539/ijsp.v14n1p50> where the interest is in a comparison of all possible elementary treatment contrasts. The package also provides an optional method of using the graphical user interface (GUI) R package tcltk to ensure that it is user friendly.

Analysis of relative cell type proportions in bulk gene expression data. Provides a well-validated set of brain cell type-specific marker genes derived from multiple types of experiments, as described in McKenzie (2018) <doi:10.1038/s41598-018-27293-5>. For brain tissue data sets, there are marker genes available for astrocytes, endothelial cells, microglia, neurons, oligodendrocytes, and oligodendrocyte precursor cells, derived from each of human, mice, and combination human/mouse data sets. However, if you have access to your own marker genes, the functions can be applied to bulk gene expression data from any tissue. Also implements multiple options for relative cell type proportion estimation using these marker genes, adapting and expanding on approaches from the CellCODE R package described in Chikina (2015) <doi:10.1093/bioinformatics/btv015>. The number of cell type marker genes used in a given analysis can be increased or decreased based on your preferences and the data set. Finally, provides functions to use the estimates to adjust for variability in the relative proportion of cell types across samples prior to downstream analyses.

Connect to the D2L Brightspace Data Sets ('BDS') API via OAuth2', download all available datasets as tidy data frames with proper types, join them using convenience functions that know the foreign key relationships, and analyse student engagement, performance, and retention with ready-made analytics functions.

An interface for the Neo4j database providing mapping between different identifiers of biological entities. This Biological Entity Dictionary (BED) has been developed to address three main challenges. The first one is related to the completeness of identifier mappings. Indeed, direct mapping information provided by the different systems are not always complete and can be enriched by mappings provided by other resources. More interestingly, direct mappings not identified by any of these resources can be indirectly inferred by using mappings to a third reference. For example, many human Ensembl gene ID are not directly mapped to any Entrez gene ID but such mappings can be inferred using respective mappings to HGNC ID. The second challenge is related to the mapping of deprecated identifiers. Indeed, entity identifiers can change from one resource release to another. The identifier history is provided by some resources, such as Ensembl or the NCBI, but it is generally not used by mapping tools. The third challenge is related to the automation of the mapping process according to the relationships between the biological entities of interest. Indeed, mapping between gene and protein ID scopes should not be done the same way than between two scopes regarding gene ID. Also, converting identifiers from different organisms should be possible using gene orthologs information. The method has been published by Godard and van Eyll (2018) <doi:10.12688/f1000research.13925.3>.

Stan-based curve-fitting function for use with package breathtestcore by the same author. Stan functions are refactored here for easier testing.

We perform general mediation analysis in the Bayesian setting using the methods described in Yu and Li (2022, ISBN:9780367365479). With the package, the mediation analysis can be performed on different types of outcomes (e.g., continuous, binary, categorical, or time-to-event), with default or user-defined priors and predictive models. The Bayesian estimates and credible sets of mediation effects are reported as analytic results.