This package implements the Self-Similarity Test for Normality (SSTN), a new statistical test designed to assess whether a given sample originates from a normal distribution. The procedure is based on iteratively estimating the characteristic function of the sum of standardized i.i.d. random variables and comparing it to the characteristic function of the standard normal distribution. A Monte Carlo procedure is used to determine the empirical distribution of the test statistic under the null hypothesis. Details of the methodology are described in Anarat and Schwender (2025), "A normality test based on self-similarity" (Submitted).

Simultaneous inference procedures for high-dimensional linear models as described by Zhang, X., and Cheng, G. (2017) <doi:10.1080/01621459.2016.1166114>.

Generates Skew Factor Models data and applies Sparse Online Principal Component (SOPC), Incremental Principal Component (IPC), Projected Principal Component (PPC), Perturbation Principal Component (PPC), Stochastic Approximation Principal Component (SAPC), Sparse Principal Component (SPC) and other PC methods to estimate model parameters. It includes capabilities for calculating mean squared error, relative error, and sparsity of the loading matrix.The philosophy of the package is described in Guo G. (2023) <doi:10.1007/s00180-022-01270-z>.

This package implements Multivariate ANalysis Of VAriance (MANOVA) parameters inference and test with regularization for semicontinuous high-dimensional data. The method can be applied also in presence of low-dimensional data. The p-value can be obtained through asymptotic distribution or using a permutation procedure. The package gives also the possibility to simulate this type of data. Method is described in Elena Sabbioni, Claudio Agostinelli and Alessio Farcomeni (2025) A regularized MANOVA test for semicontinuous high-dimensional data. Biometrical Journal, 67:e70054. DOI <doi:10.1002/bimj.70054>, arXiv DOI <doi:10.48550/arXiv.2401.04036>.

Presmoothed estimators of survival, density, cumulative and non-cumulative hazard functions with right-censored survival data. For details, see Lopez-de-Ullibarri and Jacome (2013) <doi:10.18637/jss.v054.i11>.

Extracts and summarizes metadata from data frames, including variable names, labels, types, and missing values. Computes compact descriptive statistics, frequency tables, and cross-tabulations to assist with efficient data exploration. Includes an interactive and exportable codebook generator for documenting variable metadata. Facilitates the identification of missing data patterns and structural issues in datasets. Designed to streamline initial data management and exploratory analysis workflows within R'.

Generalized additive models under shape constraints on the component functions of the linear predictor. Models can include multiple shape-constrained (univariate and bivariate) and unconstrained terms. Routines of the package mgcv are used to set up the model matrix, print, and plot the results. Multiple smoothing parameter estimation by the Generalized Cross Validation or similar. See Pya and Wood (2015) <doi:10.1007/s11222-013-9448-7> for an overview. A broad selection of shape-constrained smoothers, linear functionals of smooths with shape constraints, and Gaussian models with AR1 residuals.

The SoundexBR package provides an algorithm for decoding names into phonetic codes, as pronounced in Portuguese. The goal is for homophones to be encoded to the same representation so that they can be matched despite minor differences in spelling. The algorithm mainly encodes consonants; a vowel will not be encoded unless it is the first letter. The soundex code resultant consists of a four digits long string composed by one letter followed by three numerical digits: the letter is the first letter of the name, and the digits encode the remaining consonants.

Assigns a score projection from 0 to 1 between a given in vivo stage and each single cluster from an in vitro dataset. The score is assigned based on the the fraction of specific markers of the in vivo stage that are conserved in the in vitro clusters <https://github.com/ScialdoneLab>.

This package provides an imputation pipeline for single-cell RNA sequencing data. The scISR method uses a hypothesis-testing technique to identify zero-valued entries that are most likely affected by dropout events and estimates the dropout values using a subspace regression model (Tran et.al. (2022) <DOI:10.1038/s41598-022-06500-4>).

Simulation extrapolation and inverse probability weighted generalized estimating equations method for longitudinal data with missing observations and measurement error in covariates. References: Yi, G. Y. (2008) <doi:10.1093/biostatistics/kxm054>; Cook, J. R. and Stefanski, L. A. (1994) <doi:10.1080/01621459.1994.10476871>; Little, R. J. A. and Rubin, D. B. (2002, ISBN:978-0-471-18386-0).

Please see the shinytest to shinytest2 migration guide at <https://rstudio.github.io/shinytest2/articles/z-migration.html>.

Parametric survival regression models under the maximum likelihood approach via Stan'. Implemented regression models include accelerated failure time models, proportional hazards models, proportional odds models, accelerated hazard models, Yang and Prentice models, and extended hazard models. Available baseline survival distributions include exponential, Weibull, log-normal, log-logistic, gamma, generalized gamma, rayleigh, Gompertz and fatigue (Birnbaum-Saunders) distributions. References: Lawless (2002) <ISBN:9780471372158>; Bennett (1982) <doi:10.1002/sim.4780020223>; Chen and Wang(2000) <doi:10.1080/01621459.2000.10474236>; Demarqui and Mayrink (2021) <doi:10.1214/20-BJPS471>.

High dimensional survival data analysis with Markov Chain Monte Carlo(MCMC). Currently supports frailty data analysis. Allows for Weibull and Exponential distribution. Includes function for interval censored data.

Studies otolith shape variation among fish populations. Otoliths are calcified structures found in the inner ear of teleost fish and their shape has been known to vary among several fish populations and stocks, making them very useful in taxonomy, species identification and to study geographic variations. The package extends previously described software used for otolith shape analysis by allowing the user to automatically extract closed contour outlines from a large number of images, perform smoothing to eliminate pixel noise described in Haines and Crampton (2000) <doi:10.1111/1475-4983.00148>, choose from conducting either a Fourier or wavelet see Gençay et al (2001) <doi:10.1016/S0378-4371(00)00463-5> transform to the outlines and visualize the mean shape. The output of the package are independent Fourier or wavelet coefficients which can be directly imported into a wide range of statistical packages in R. The package might prove useful in studies of any two dimensional objects.

Stochastic frontier analysis with advanced methods. In particular, it applies the approach proposed by Latruffe et al. (2017) <DOI:10.1093/ajae/aaw077> to estimate a stochastic frontier with technical inefficiency effects when one input is endogenous.

Trains neural networks (multilayer perceptrons with one hidden layer) for bi- or multi-class classification.

Some R functions, such as optim(), require a function its gradient passed as separate arguments. When these are expensive to calculate it may be much faster to calculate the function (fn) and gradient (gr) together since they often share many calculations (chain rule). This package allows the user to pass in a single function that returns both the function and gradient, then splits (hence splitfngr') them so the results can be accessed separately. The functions provided allow this to be done with any number of functions/values, not just for functions and gradients.

Integrating a stratified structure in the population in a sampling design can considerably reduce the variance of the Horvitz-Thompson estimator. We propose in this package different methods to handle the selection of a balanced sample in stratified population. For more details see Raphaël Jauslin, Esther Eustache and Yves Tillé (2021) <doi:10.1007/s42081-021-00134-y>. The package propose also a method based on optimal transport and balanced sampling, see Raphaël Jauslin and Yves Tillé <doi:10.1016/j.jspi.2022.12.003>.

This package provides functions to non-parametrically estimate the off-pulse interval of a source function originating from a pulsar. The technique is based on a sequential application of P-values obtained from goodness-of-fit tests for the uniform distribution, such as the Kolmogorov-Smirnov, Cramer-von Mises, Anderson-Darling and Rayleigh goodness-of-fit tests.

This package provides functions for reading and writing Gadget N-body snapshots. The Gadget code is popular in astronomy for running N-body / hydrodynamical cosmological and merger simulations. To find out more about Gadget see the main distribution page at www.mpa-garching.mpg.de/gadget/.

This package provides functions for creating and manipulating 12-tone (i.e., dodecaphonic) musical matrices using Arnold Schoenberg's (1923) serialism technique. This package can generate random 12-tone matrices and can generate matrices using a pre-determined sequence of notes.

Kataegis is a localized hypermutation occurring when a region is enriched in somatic SNVs. Kataegis can result from multiple cytosine deaminations catalyzed by the AID/APOBEC family of proteins. This package contains functions to detect kataegis from SNVs in BED format. This package reports two scores per kataegic event, a hypermutation score and an APOBEC mediated kataegic score. Yousif, F. et al.; The Origins and Consequences of Localized and Global Somatic Hypermutation; Biorxiv 2018 <doi:10.1101/287839>.

This package provides Markov Chain Monte Carlo (MCMC) routine for the structural equation modelling described in Maity et. al. (2020) <doi:10.1093/bioinformatics/btaa286>. This MCMC sampler is useful when one attempts to perform an integrative survival analysis for multiple platforms of the Omics data where the response is time to event and the predictors are different omics expressions for different platforms.