This package provides a suite of tools to allow you to download all publicly available parasite rate survey points, mosquito occurrence points and raster surfaces from the Malaria Atlas Project <https://malariaatlas.org/> servers as well as utility functions for plotting the downloaded data.

This package provides a framework based on S3 dispatch for constructing models of mosquito-borne pathogen transmission which are constructed from submodels of various components (i.e. immature and adult mosquitoes, human populations). A consistent mathematical expression for the distribution of bites on hosts means that different models (stochastic, deterministic, etc.) can be coherently incorporated and updated over a discrete time step.

Shiny web application to run meta-analyses. Essentially a graphical front-end to package meta for R. Can be useful as an educational tool, and for quickly analyzing and sharing meta-analyses. Provides output to quickly fill in GRADE (Grading of Recommendations, Assessment, Development and Evaluations) Summary-of-Findings tables. Importantly, it allows further processing of the results inside R, in case more specific analyses are needed.

This is an add-on package to the monobin package that simplifies its use. It provides shiny-based user interface (UI) that is especially handy for less experienced R users as well as for those who intend to perform quick scanning of numeric risk factors when building credit rating models. The additional functions implemented in monobinShiny that do no exist in monobin package are: descriptive statistics, special case and outliers imputation. The function descriptive statistics is exported and can be used in R sessions independently from the user interface, while special case and outlier imputation functions are written to be used with shiny UI.

This group of functions simplifies the creation of linked micromap plots. Please see <https://www.jstatsoft.org/v63/i02/> for additional details.

This function allows to generate two biological conditions synthetic microarray dataset which has similar behavior to those currently observed with common platforms. User provides a subset of parameters. Available default parameters settings can be modified.

This package provides a generalised workflow for Matching-Adjusted Indirect Comparison (MAIC) analysis, which supports both anchored and non-anchored MAIC methods. In MAIC, unbiased trial outcome comparison is achieved by weighting the subject-level outcomes of the intervention trial so that the weighted aggregate measures of prognostic or effect-modifying variables match those of the comparator trial. Measurements supported include time-to-event (e.g., overall survival) and binary (e.g., objective tumor response). The method is described in Signorovitch et al. (2010) <doi:10.2165/11538370-000000000-00000> and Signorovitch et al. (2012) <doi:10.1016/j.jval.2012.05.004>.

This package provides tools for high-dimensional peaks-over-threshold inference and simulation of Brown-Resnick and extremal Student spatial extremal processes. These include optimization routines based on censored likelihood and gradient scoring, and exact simulation algorithms for max-stable and multivariate Pareto distributions based on rejection sampling. Fast multivariate Gaussian and Student distribution functions using separation-of-variable algorithm with quasi Monte Carlo integration are also provided. Key references include de Fondeville and Davison (2018) <doi:10.1093/biomet/asy026>, Thibaud and Opitz (2015) <doi:10.1093/biomet/asv045>, Wadsworth and Tawn (2014) <doi:10.1093/biomet/ast042> and Genz and Bretz (2009) <doi:10.1007/978-3-642-01689-9>.

Generates Raven like matrices according to different rules and the response list associated to the matrix. The package can generate matrices composed of 4 or 9 cells, along with a response list of 11 elements (the correct response + 10 incorrect responses). The matrices can be generated according to both logical rules (i.e., the relationships between the elements in the matrix are manipulated to create the matrix) and visual-spatial rules (i.e., the visual or spatial characteristics of the elements are manipulated to generate the matrix). The graphical elements of this package are based on the DescTools package. This package has been developed within the PRIN2020 Project (Prot. 20209WKCLL) titled "Computerized, Adaptive and Personalized Assessment of Executive Functions and Fluid Intelligence" and founded by the Italian Ministry of Education and Research.

Age-specific mortality rates are estimated and projected using the Kannisto, Lee-Carter and related methods as described in Sevcikova et al. (2016) <doi:10.1007/978-3-319-26603-9_15>.

The ultimate goal is to support 2-2-1, 2-1-1, and 1-1-1 models for multilevel mediation, the option of a moderating variable for either the a, b, or both paths, and covariates. Currently the 1-1-1 model is supported and several options of random effects; the initial code for bootstrapping was evaluated in simulations by Falk, Vogel, Hammami, and MioÄ eviÄ (2024) <doi:10.3758/s13428-023-02079-4>. Support for Bayesian estimation using brms comprises ongoing work. Currently only continuous mediators and outcomes are supported. Factors for any predictors must be numerically represented.

This package provides fast and accurate inference for the parameter estimation problem in Ordinary Differential Equations, including the case when there are unobserved system components. Implements the MAGI method (MAnifold-constrained Gaussian process Inference) of Yang, Wong, and Kou (2021) <doi:10.1073/pnas.2020397118>. A user guide is provided by the accompanying software paper Wong, Yang, and Kou (2024) <doi:10.18637/jss.v109.i04>.

The MSiP is a computational approach to predict protein-protein interactions from large-scale affinity purification mass spectrometry (AP-MS) data. This approach includes both spoke and matrix models for interpreting AP-MS data in a network context. The "spoke" model considers only bait-prey interactions, whereas the "matrix" model assumes that each of the identified proteins (baits and prey) in a given AP-MS experiment interacts with each of the others. The spoke model has a high false-negative rate, whereas the matrix model has a high false-positive rate. Although, both statistical models have merits, a combination of both models has shown to increase the performance of machine learning classifiers in terms of their capabilities in discrimination between true and false positive interactions.

There is an increasing interest in investigating how the compositions of microbial communities are associated with human health and disease. In this package, we present a novel global testing method called aMiSPU, that is highly adaptive and thus high powered across various scenarios, alleviating the issue with the choice of a phylogenetic distance. Our simulations and real data analysis demonstrated that aMiSPU test was often more powerful than several competing methods while correctly controlling type I error rates.

This package provides a method for the multiresolution analysis of spatial fields and images to capture scale-dependent features. mrbsizeR is based on scale space smoothing and uses differences of smooths at neighbouring scales for finding features on different scales. To infer which of the captured features are credible, Bayesian analysis is used. The scale space multiresolution analysis has three steps: (1) Bayesian signal reconstruction. (2) Using differences of smooths, scale-dependent features of the reconstructed signal can be found. (3) Posterior credibility analysis of the differences of smooths created. The method has first been proposed by Holmstrom, Pasanen, Furrer, Sain (2011) <DOI:10.1016/j.csda.2011.04.011> and extended in Flury, Gerber, Schmid and Furrer (2021) <DOI:10.1016/j.spasta.2020.100483>.

Facilitates creation and manipulation of metric graphs, such as street or river networks. Further facilitates operations and visualizations of data on metric graphs, and the creation of a large class of random fields and stochastic partial differential equations on such spaces. These random fields can be used for simulation, prediction and inference. In particular, linear mixed effects models including random field components can be fitted to data based on computationally efficient sparse matrix representations. Interfaces to the R packages INLA and inlabru are also provided, which facilitate working with Bayesian statistical models on metric graphs. The main references for the methods are Bolin, Simas and Wallin (2024) <doi:10.3150/23-BEJ1647>, Bolin, Kovacs, Kumar and Simas (2023) <doi:10.1090/mcom/3929> and Bolin, Simas and Wallin (2023) <doi:10.48550/arXiv.2304.03190> and <doi:10.48550/arXiv.2304.10372>.

This package performs Bayesian meta-analysis, meta-regression and model-based meta-analysis using Stan'. Includes binomial-normal hierarchical models and option to use weakly informative priors for the heterogeneity parameter and the treatment effect parameter which are described in Guenhan, Roever, and Friede (2020) <doi:10.1002/jrsm.1370>.

You can apply image processing effects that modifies the perceived material properties of objects in photos, such as gloss, smoothness, and blemishes. This is an implementation of the algorithm proposed by Boyadzhiev et al. (2015) "Band-Sifting Decomposition for Image Based Material Editing". Documentation and practical tips of the package is available at <https://github.com/tsuda16k/materialmodifier>.

Mitteroecker & Gunz (2009) <doi:10.1007/s11692-009-9055-x> describe how geometric morphometric methods allow researchers to quantify the size and shape of physical biological structures. We provide tools to extend geometric morphometric principles to the study of non-physical structures, hormone profiles, as outlined in Ehrlich et al (2021) <doi:10.1002/ajpa.24514>. Easily transform daily measures into multivariate landmark-based data. Includes custom functions to apply multivariate methods for data exploration as well as hypothesis testing. Also includes shiny web app to streamline data exploration. Developed to study menstrual cycle hormones but functions have been generalized and should be applicable to any biomarker over any time period.

The multiple instance data set consists of many independent subjects (called bags) and each subject is composed of several components (called instances). The outcomes of such data set are binary or categorical responses, and, we can only observe the subject-level outcomes. For example, in manufacturing processes, a subject is labeled as "defective" if at least one of its own components is defective, and otherwise, is labeled as "non-defective". The milr package focuses on the predictive model for the multiple instance data set with binary outcomes and performs the maximum likelihood estimation with the Expectation-Maximization algorithm under the framework of logistic regression. Moreover, the LASSO penalty is attached to the likelihood function for simultaneous parameter estimation and variable selection.

Multiscale Graph Correlation (MGC) is a framework developed by Vogelstein et al. (2019) <DOI:10.7554/eLife.41690> that extends global correlation procedures to be multiscale; consequently, MGC tests typically require far fewer samples than existing methods for a wide variety of dependence structures and dimensionalities, while maintaining computational efficiency. Moreover, MGC provides a simple and elegant multiscale characterization of the potentially complex latent geometry underlying the relationship.

Offering enhanced statistical power compared to traditional hypothesis testing methods, informative hypothesis testing allows researchers to explicitly model their expectations regarding the relationships among parameters. An important software tool for this framework is restriktor'. The mmirestriktor package provides shiny web applications to implement some of the basic functionality of restriktor'. The mmirestriktor() function launches a shiny application for fitting and analyzing models with constraints. The FbarCards() function launches a card game application which can help build intuition about informative hypothesis testing. The iht_interpreter() helps interpret informative hypothesis testing results based on guidelines in Vanbrabant and Rosseel (2020) <doi:10.4324/9780429273872-14>.

This package provides functions for model-based response dimension reduction. Usual dimension reduction methods in multivariate regression focus on the reduction of predictors, not responses. The response dimension reduction is theoretically founded in Yoo and Cook (2008) <doi:10.1016/j.csda.2008.07.029>. Later, three model-based response dimension reduction approaches are proposed in Yoo (2016) <doi:10.1080/02331888.2017.1410152> and Yoo (2019) <doi:10.1016/j.jkss.2019.02.001>. The method by Yoo and Cook (2008) is based on non-parametric ordinary least squares, but the model-based approaches are done through maximum likelihood estimation. For two model-based response dimension reduction methods called principal fitted response reduction and unstructured principal fitted response reduction, chi-squared tests are provided for determining the dimension of the response subspace.

This is a cross-platform linear model to SQL compiler. It generates SQL from linear and generalized linear models. Its interface consists of a single function, modelc(), which takes the output of lm() or glm() functions (or any object which has the same signature) and outputs a SQL character vector representing the predictions on the scale of the response variable as described in Dunn & Smith (2018) <doi:10.1007/978-1-4419-0118-7> and originating in Nelder & Wedderburn (1972) <doi:10.2307/2344614>. The resultant SQL can be included in a SELECT statement and returns output similar to that of the glm.predict() or lm.predict() predictions, assuming numeric types are represented in the database using sufficient precision. Currently log and identity link functions are supported.