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Automate the detection of gaps and elevations in mapped sequencing read coverage using a 2D pattern-matching algorithm. ProActive detects, characterizes and visualizes read coverage patterns in both genomes and metagenomes. Optionally, users may provide gene annotations associated with their genome or metagenome in the form of a .gff file. In this case, ProActive will generate an additional output table containing the gene annotations found within the detected regions of gapped and elevated read coverage. Additionally, users can search for gene annotations of interest in the output read coverage plots.
Clustering analysis for sparse microbiome data, based on a Poisson hurdle model.
Reproducible, programmatic retrieval of survey datasets from the Pew Research Center.
Performant interactive scatterplot for ~ 1 million points. Zoom, pan, and pick points. Includes tooltips, labels, a grid overlay, legend, and coupled interactions across multiple plots.
To take nested function calls and convert them to a more readable form using pipes from package magrittr'.
Reads the provenance collected by the rdtLite or rdt packages, or other tools providing compatible PROV JSON output, created by the execution of a script or a console session, and provides a human-readable summary identifying the input and output files, the scripts used (if any), errors and warnings produced, and the environment in which it was executed. It can also optionally package all the files into a zip file. The exact format of the PROV JSON file created by rdtLite and rdt is described in <https://github.com/End-to-end-provenance/ExtendedProvJson>. More information about rdtLite and associated tools is available at <https://github.com/End-to-end-provenance/> and Lerner, Boose, and Perez (2018), Using Introspection to Collect Provenance in R, Informatics, <doi: 10.3390/informatics5010012>.
The prevalence package provides Frequentist and Bayesian methods for prevalence assessment studies. IMPORTANT: the truePrev functions in the prevalence package call on JAGS (Just Another Gibbs Sampler), which therefore has to be available on the user's system. JAGS can be downloaded from <https://mcmc-jags.sourceforge.io/>.
Tests for a comparison of two partially overlapping samples. A comparison of means using the partially overlapping samples t-test: See Derrick, Russ, Toher and White (2017), Test statistics for the comparison of means for two samples which include both paired observations and independent observations, Journal of Modern Applied Statistical Methods, 16(1). A comparison of proportions using the partially overlapping samples z-test: See Derrick, Dobson-Mckittrick, Toher and White (2015), Test statistics for comparing two proportions with partially overlapping samples. Journal of Applied Quantitative Methods, 10(3).
This package provides a framework for creating interactive figures for data exploration. All plots are automatically linked and support several kinds of interactive features, including selection, zooming, panning, and parameter manipulation. The figures can be interacted with either manually, using a mouse and a keyboard, or by running code from inside an active R session.
Estimate complex Structural Equation Models (SEMs) by fitting Partial Least Squares Structural Equation Modeling (PLS-SEM) and Partial Least Squares consistent Structural Equation Modeling (PLSc-SEM) specifications that handle categorical data, non-linear relations, and multilevel structures. The implementation follows Lohmöller (1989) for the classic PLS-SEM algorithm, Dijkstra and Henseler (2015) for consistent PLSc-SEM, Dijkstra et al., (2014) for nonlinear PLSc-SEM, and Schuberth, Henseler, Dijkstra (2018) for ordinal PLS-SEM and PLSc-SEM. Additional extensions are under development. The MC-OrdPLSc algorithm, used to handle ordinal interaction models is detailed in Slupphaug et al., (2026). References: Lohmöller, J.-B. (1989, ISBN:9783790803002). "Latent Variable Path Modeling with Partial Least Squares." Dijkstra, T. K., & Henseler, J. (2015). <doi:10.1016/j.jmva.2015.06.002>. "Consistent partial least squares path modeling." Dijkstra, T. K., & Schermelleh-Engel, K. (2014). <doi:10.1016/j.csda.2014.07.008>. "Consistent partial least squares for nonlinear structural equation models." Schuberth, F., Henseler, J., & Dijkstra, T. K. (2018). <doi:10.1007/s11135-018-0767-9>. "Partial least squares path modeling using ordinal categorical indicators." Slupphaug, K. Mehmetoglu, M. & Mittner, M. (2026). <doi:10.31234/osf.io/fwzj6_v1>. "Consistent Estimates from Biased Estimators: Monte-Carlo Consistent Partial Least Squares for Latent Interaction Models with Ordinal Indicators.".
This package provides functions to get prediction intervals and prediction points of future observations from mixture distributions like gamma, beta, Weibull and normal.
Extract political party colors and logos from English Wikipedia party pages. Provides functions to scrape party infoboxes for color codes (HEX or HTML color names) and logo images. Includes integration with the Party Facts database for easy party lookups. Designed for political scientists and party researchers working with electoral and party data. For Party Facts, see Döring and Regel (2019) <doi:10.1177/1354068818820671> and Bederke, Döring, and Regel (2023) <doi:10.7910/DVN/TJINLQ>.
This package provides tools for fitting piecewise-constant hazard models for survival and competing risks data, including ensemble hazard estimation via the Super Learner framework. The package supports estimation of survival functions and absolute risk predictions from fitted cause-specific hazard models. For the Super Learner framework see van der Laan, Polley and Hubbard (2007) <doi:10.2202/1544-6115.1309>.
Computes penalized regression calibration (PRC), a statistical method for the dynamic prediction of survival when many longitudinal predictors are available. See Signorelli (2024) <doi:10.32614/RJ-2024-014> and Signorelli et al. (2021) <doi:10.1002/sim.9178> for details.
Computes the Patient-Reported Outcomes (PROs) Joint Contrast (PJC), a residual-based summary that captures information left over after accounting for the clinical Disease Activity index for Psoriatic Arthritis (cDAPSA). PROs (pain and patient global assessment) and joint counts (swollen and tender) are standardized, then each component is adjusted for standardized cDAPSA using natural spline coefficients that were derived from previously published models. The resulting residuals are standardized and combined using fixed principal component loadings, to yield a continuous PJC score and quartile groupings. This package provides a calculator for applying those published coefficients to new datasets; it does not itself estimate spline models or principal components.
Create and customize interactive phylogenetic trees using the phylocanvas JavaScript library and the htmlwidgets package. These trees can be used directly from the R console, from RStudio', in Shiny apps, and in R Markdown documents. See <http://phylocanvas.org/> for more information on the phylocanvas library.
The welfare's synthetic indicator provides an ideal tool for measuring multi-dimensional concepts such as welfare, development, living standards, etc. It enables information from the various indicators to be aggregated into a single synthetic measure. The method was proposed by Pena (1977, ISBN:9788426001788) and further developed by Zarzosa and Somarriba (2012) <doi:10.1007/s11205-012-0005-0>.
This package implements tools for the analysis of partially ordered data, with a particular focus on the evaluation of multidimensional systems of indicators and on the analysis of poverty. References, Fattore M. (2016) <doi:10.1007/s11205-015-1059-6> Fattore M., Arcagni A. (2016) <doi:10.1007/s11205-016-1501-4> Arcagni A. (2017) <doi:10.1007/978-3-319-45421-4_19>.
Given an arbitrary set of spatial regions and road networks, generate a set of representative points, or pseudohouseholds, that can be used for travel burden analysis. Parallel processing is supported.
This package provides a new metric named dependency heaviness is proposed that measures the number of additional dependency packages that a parent package brings to its child package and are unique to the dependency packages imported by all other parents. The dependency heaviness analysis is visualized by a customized heatmap. The package is described in <doi:10.1093/bioinformatics/btac449>. We have also performed the dependency heaviness analysis on the CRAN/Bioconductor package ecosystem, described in <doi:10.1016/j.jss.2023.111610>.
Compiles functions to trim, bin, visualise, and analyse activity/sleep time-series data collected from the Drosophila Activity Monitor (DAM) system (Trikinetics, USA). The following methods were used to compute periodograms - Chi-square periodogram: Sokolove and Bushell (1978) <doi:10.1016/0022-5193(78)90022-X>, Lomb-Scargle periodogram: Lomb (1976) <doi:10.1007/BF00648343>, Scargle (1982) <doi:10.1086/160554> and Ruf (1999) <doi:10.1076/brhm.30.2.178.1422>, and Autocorrelation: Eijzenbach et al. (1986) <doi:10.1111/j.1440-1681.1986.tb00943.x>. Identification of activity peaks is done after using a Savitzky-Golay filter (Savitzky and Golay (1964) <doi:10.1021/ac60214a047>) to smooth raw activity data. Three methods to estimate anticipation of activity are used based on the following papers - Slope method: Fernandez et al. (2020) <doi:10.1016/j.cub.2020.04.025>, Harrisingh method: Harrisingh et al. (2007) <doi:10.1523/JNEUROSCI.3680-07.2007>, and Stoleru method: Stoleru et al. (2004) <doi:10.1038/nature02926>. Rose plots and circular analysis are based on methods from - Batschelet (1981) <ISBN:0120810506> and Zar (2010) <ISBN:0321656865>.
An embedded proximal interior point quadratic programming solver, which can solve dense and sparse quadratic programs, described in Schwan, Jiang, Kuhn, and Jones (2023) <doi:10.48550/arXiv.2304.00290>. Combining an infeasible interior point method with the proximal method of multipliers, the algorithm can handle ill-conditioned convex quadratic programming problems without the need for linear independence of the constraints. The solver is written in header only C++ 14 leveraging the Eigen library for vectorized linear algebra. For small dense problems, vectorized instructions and cache locality can be exploited more efficiently. Allocation free problem updates and re-solves are also provided.
Calculate the optimal vertex partition of a graph using the persistence as objective function. These subroutines have been used in Avellone et al. <doi:10.1007/s10288-023-00559-z> and Avellone et al. <doi:10.1016/j.ins.2025.123032>. This package is deprecated and has been superseded by the scalednap package, which provides the same functionality and additional features; new and existing users should install scalednap instead.
Several functions are provided to implement a MBPLSDA : components search, optimal model components number search, optimal model validity test by permutation tests, observed values evaluation of optimal model parameters and predicted categories, bootstrap values evaluation of optimal model parameters and predicted cross-validated categories. The use of this package is described in Brandolini-Bunlon et al (2019. Multi-block PLS discriminant analysis for the joint analysis of metabolomic and epidemiological data. Metabolomics, 15(10):134).