Analyse prescription drug deliveries to calculate several indicators of polypharmacy corresponding to the various definitions found in the literature. Bjerrum, L., Rosholm, J. U., Hallas, J., & Kragstrup, J. (1997) <doi:10.1007/s002280050329>. Chan, D.-C., Hao, Y.-T., & Wu, S.-C. (2009a) <doi:10.1002/pds.1712>. Fincke, B. G., Snyder, K., Cantillon, C., Gaehde, S., Standring, P., Fiore, L., ... Gagnon, D.R. (2005) <doi:10.1002/pds.966>. Hovstadius, B., Astrand, B., & Petersson, G. (2009) <doi:10.1186/1472-6904-9-11>. Hovstadius, B., Astrand, B., & Petersson, G. (2010) <doi:10.1002/pds.1921>. Kennerfalk, A., Ruigómez, A., Wallander, M.-A., Wilhelmsen, L., & Johansson, S. (2002) <doi:10.1345/aph.1A226>. Masnoon, N., Shakib, S., Kalisch-Ellett, L., & Caughey, G. E. (2017) <doi:10.1186/s12877-017-0621-2>. Narayan, S. W., & Nishtala, P. S. (2015) <doi:10.1007/s40801-015-0020-y>. Nishtala, P. S., & Salahudeen, M. S. (2015) <doi:10.1159/000368191>. Park, H. Y., Ryu, H. N., Shim, M. K., Sohn, H. S., & Kwon, J. W. (2016) <doi:10.5414/cp202484>. Veehof, L., Stewart, R., Haaijer-Ruskamp, F., & Jong, B. M. (2000) <doi:10.1093/fampra/17.3.261>.

This package provides functions for conducting power analysis in ANOVA designs, including between-, within-, and mixed-factor designs, with full support for both main effects and interactions. The package allows calculation of statistical power, required total sample size, significance level, and minimal detectable effect sizes expressed as partial eta squared or Cohen's f for ANOVA terms and planned contrasts. In addition, complementary functions are included for common related tests such as t-tests and correlation tests, making the package a convenient toolkit for power analysis in experimental psychology and related fields.

Based on (but not identical to) the no-longer-maintained package phyext', provides enhancements to phylobase classes, specifically for use by package SigTree'; provides classes and methods which help users manipulate branch-annotated trees (as in SigTree'); also provides support for a few other extra features.

This package provides tools for the evaluation of interim analysis plans for sequentially monitored trials on a survival endpoint; tools to construct efficacy and futility boundaries, for deriving power of a sequential design at a specified alternative, template for evaluating the performance of candidate plans at a set of time varying alternatives. See Izmirlian, G. (2014) <doi:10.4310/SII.2014.v7.n1.a4>.

We aim for fitting a multinomial regression model with Lasso penalty and doing statistical inference (calculating confidence intervals of coefficients and p-values for individual variables). It implements 1) the coordinate descent algorithm to fit an l1-penalized multinomial regression model (parameterized with a reference level); 2) the debiasing approach to obtain the inference results, which is described in "Tian, Y., Rusinek, H., Masurkar, A. V., & Feng, Y. (2024). L1â Penalized Multinomial Regression: Estimation, Inference, and Prediction, With an Application to Risk Factor Identification for Different Dementia Subtypes. Statistics in Medicine, 43(30), 5711-5747.".

This program contains a function to find the peaks and troughs of a data set. It filters the set of peaks to remove noise based on the expected height and expected slope of a peak. Peaks that are too short (caused by random noise), or too shallow (part of the background data) are filtered out.

This package implements projected sparse Gaussian process Kriging ('Ingram et. al.', 2008, <doi:10.1007/s00477-007-0163-9>) as an additional method for the intamap package. More details on implementation ('Barillec et. al.', 2010, <doi:10.1016/j.cageo.2010.05.008>).

Includes tools to calculate statistical power, minimum detectable effect size (MDES), MDES difference (MDESD), and minimum required sample size for various multilevel randomized experiments (MRE) with continuous outcomes. Accomodates 14 types of MRE designs to detect main treatment effect, seven types of MRE designs to detect moderated treatment effect (2-1-1, 2-1-2, 2-2-1, 2-2-2, 3-3-1, 3-3-2, and 3-3-3 designs; <total.lev> - <trt.lev> - <mod.lev>), five types of MRE designs to detect mediated treatment effects (2-1-1, 2-2-1, 3-1-1, 3-2-1, and 3-3-1 designs; <trt.lev> - <med.lev> - <out.lev>), four types of partially nested (PN) design to detect main treatment effect, and three types of PN designs to detect mediated treatment effects (2/1, 3/1, 3/2; <trt.arm.lev> / <ctrl.arm.lev>). See PowerUp! Excel series at <https://www.causalevaluation.org/>.

The goal of PlotFTIR is to easily and quickly kick-start the production of journal-quality Fourier Transform Infra-Red (FTIR) spectral plots in R using ggplot2'. The produced plots can be published directly or further modified by ggplot2 functions. L'objectif de PlotFTIR est de démarrer facilement et rapidement la production des tracés spectraux de spectroscopie infrarouge à transformée de Fourier (IRTF) de qualité journal dans R à l'aide de ggplot2'. Les tracés produits peuvent être publiés directement ou modifiés davantage par les fonctions ggplot2'.

Data sets for the Panel Data Econometrics with R <doi:10.1002/9781119504641> book.

This package provides a set of raw datasets used to create SDTM domains in pharmaversesdtm package.

This package provides a Shiny Web Application to predict and visualize concentrations of pharmaceuticals in the aqueous environment. Jagadeesan K., Barden R. and Kasprzyk-Hordern B. (2022) <https://www.ssrn.com/abstract=4306129>.

This package provides tools for scraping match statistics and player data from the Athletes Unlimited (UA) website <https://auprosports.com/volleyball/>, the League One Volleyball website <https://lovb.com>, and the Major League (MLV) website <https://provolleyball.com>.

This package implements L1 and L2 penalized conditional logistic regression with penalty factors allowing for integration of multiple data sources. Implements stability selection for variable selection.

Kernel density estimation with global bandwidth selection via "plug-in".

For a data matrix with m rows and n columns (m>=n), the power method is used to compute, simultaneously, the eigendecomposition of a square symmetric matrix. This result is used to obtain the singular value decomposition (SVD) and the principal component analysis (PCA) results. Compared to the classical SVD method, the first r singular values can be computed.

Store and retrieve data from options() using syntax derived from the here package. potions makes it straightforward to update and retrieve options, either in the workspace or during package development, without overwriting global options.

Considering the singly imputed synthetic data generated via plug-in sampling under the multivariate normal model, draws inference procedures including the generalized variance, the sphericity test, the test for independence between two subsets of variables, and the test for the regression of one set of variables on the other. For more details see Klein et al. (2021) <doi:10.1007/s13571-019-00215-9>.

Reconstruction of paleoclimate niches using phylogenetic comparative methods and projection reconstructed niches onto paleoclimate maps. The user can specify various models of trait evolution or estimate the best fit model, include fossils, use one or multiple phylogenies for inference, and make animations of shifting suitable habitat through time. This model was first used in Lawing and Polly (2011), and further implemented in Lawing et al (2016) and Rivera et al (2020). Lawing and Polly (2011) <doi:10.1371/journal.pone.0028554> "Pleistocene climate, phylogeny and climate envelope models: An integrative approach to better understand species response to climate change" Lawing et al (2016) <doi:10.1086/687202> "Including fossils in phylogenetic climate reconstructions: A deep time perspective on the climatic niche evolution and diversification of spiny lizards (Sceloporus)" Rivera et al (2020) <doi:10.1111/jbi.13915> "Reconstructing historical shifts in suitable habitat of Sceloporus lineages using phylogenetic niche modelling.".

Fast functions for dealing with prime numbers, such as testing whether a number is prime and generating a sequence prime numbers. Additional functions include finding prime factors and Ruth-Aaron pairs, finding next and previous prime numbers in the series, finding or estimating the nth prime, estimating the number of primes less than or equal to an arbitrary number, computing primorials, prime k-tuples (e.g., twin primes), finding the greatest common divisor and smallest (least) common multiple, testing whether two numbers are coprime, and computing Euler's totient function. Most functions are vectorized for speed and convenience.

Check if a remote computer is up. It can either just call the system ping command, or check a specified TCP port.

Miscellaneous utilities for parallelizing large computations. Alternative to MapReduce. File splitting and distributed operations such as sort and aggregate. "Software Alchemy" method for parallelizing most statistical methods, presented in N. Matloff, Parallel Computation for Data Science, Chapman and Hall, 2015. Includes a debugging aid.

This package contains various tools for conveniently downloading and editing taxon-specific datasets from the Paleobiology Database <https://paleobiodb.org>, extracting information on abundance, temporal distribution of subtaxa and taxonomic diversity through deep time, and visualizing these data in relation to phylogeny and stratigraphy.

Calculates multivariate analysis of variance based on permutations and some associated pictorial representations. The pictorial representation is based on the principal coordinates of the group means. There are some original results that will be published soon.