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Generalized competing event model based on Cox PH model and Fine-Gray model. This function is designed to develop optimized risk-stratification methods for competing risks data, such as described in: 1. Carmona R, Gulaya S, Murphy JD, Rose BS, Wu J, Noticewala S,McHale MT, Yashar CM, Vaida F, and Mell LK (2014) <DOI:10.1016/j.ijrobp.2014.03.047>. 2. Carmona R, Zakeri K, Green G, Hwang L, Gulaya S, Xu B, Verma R, Williamson CW, Triplett DP, Rose BS, Shen H, Vaida F, Murphy JD, and Mell LK (2016) <DOI:10.1200/JCO.2015.65.0739>. 3. Lunn, Mary, and Don McNeil (1995) <DOI:10.2307/2532940>.
This package provides tools for efficient processing of large, whole genome genotype data sets in variant call format (VCF). It includes several functions to calculate commonly used population genomic metrics and a method for reference panel free genotype imputation, which is described in the preprint Gurke & Mayer (2024) <doi:10.22541/au.172515591.10119928/v1>.
This package provides tools for plotting gene clusters and transcripts by importing data from GenBank, FASTA, and GFF files. It performs BLASTP and MUMmer alignments [Altschul et al. (1990) <doi:10.1016/S0022-2836(05)80360-2>; Delcher et al. (1999) <doi:10.1093/nar/27.11.2369>] and displays results on gene arrow maps. Extensive customization options are available, including legends, labels, annotations, scales, colors, tooltips, and more.
R provides fantastic tools for changepoint analysis, but plots generated by the tools do not have the ggplot2 style. This tool, however, combines changepoint', changepoint.np and ecp together, and uses ggplot2 to visualize changepoints.
Streamlines downloading and cleaning biodiversity data from Integrated Digitized Biocollections (iDigBio) and the Global Biodiversity Information Facility (GBIF).
This package provides a quick and easy way of plotting the columns of two matrices or data frames against each other using ggplot2'. Although ggmatplot doesn't provide the same flexibility as ggplot2', it can be used as a workaround for having to wrangle wide format data into long format for plotting with ggplot2'.
Promote access to the GESLA <https://gesla787883612.wordpress.com> (Global Extreme Sea Level Analysis) dataset, a higher-frequency sea-level record data from all over the world. It provides functions to download it entirely, or query subsets directly into R, without the need of downloading the full dataset. Also, it provides a built-in web-application, so that users can apply basic filters to select the data of interest, generating informative plots, and showing the selected sites.
Estimates statistically significant marker combination values within which one immunologically distinctive group (i.e., disease case) is more associated than another group (i.e., healthy control), successively, using various combinations (i.e., "gates") of markers to examine features of cells that may be different between groups. For a two-group comparison, the gateR package uses the spatial relative risk function estimated using the sparr package. Details about the sparr package methods can be found in the tutorial: Davies et al. (2018) <doi:10.1002/sim.7577>. Details about kernel density estimation can be found in J. F. Bithell (1990) <doi:10.1002/sim.4780090616>. More information about relative risk functions using kernel density estimation can be found in J. F. Bithell (1991) <doi:10.1002/sim.4780101112>.
DNA methylation of 5-methylcytosine (5mC) is the result of a multi-step, enzyme-dependent process. Predicting these sites in-vitro is laborious, time consuming as well as costly. This Gb5mC-Pred package is an in-silico pipeline for predicting DNA sequences containing the 5mC sites. It uses a machine learning approach which uses Stochastic Gradient Boosting approach for prediction of the sequences with 5mC sites. This package has been developed by using the concept of Navarez and Roxas (2022) <doi:10.1109/TCBB.2021.3082184>.
Shiny application for the analysis of groundwater monitoring data, designed to work with simple time-series data for solute concentration and ground water elevation, but can also plot non-aqueous phase liquid (NAPL) thickness if required. Also provides the import of a site basemap in GIS shapefile format.
Fit penalized multivariable linear mixed models with a single random effect to control for population structure in genetic association studies. The goal is to simultaneously fit many genetic variants at the same time, in order to select markers that are independently associated with the response. Can also handle prior annotation information, for example, rare variants, in the form of variable weights. For more information, see the website below and the accompanying paper: Bhatnagar et al., "Simultaneous SNP selection and adjustment for population structure in high dimensional prediction models", 2020, <DOI:10.1371/journal.pgen.1008766>.
This package provides a workflow for correction of Differential Interferometric Synthetic Aperture Radar (DInSAR) atmospheric delay base on Generic Atmospheric Correction Online Service for InSAR (GACOS) data and correction algorithms proposed by Chen Yu. This package calculate the Both Zenith and LOS direction (User Depend). You have to just download GACOS product on your area and preprocessed D-InSAR unwrapped images. Cite those references and this package in your work, when using this framework. References: Yu, C., N. T. Penna, and Z. Li (2017) <doi:10.1016/j.rse.2017.10.038>. Yu, C., Li, Z., & Penna, N. T. (2017) <doi:10.1016/j.rse.2017.10.038>. Yu, C., Penna, N. T., and Li, Z. (2017) <doi:10.1002/2016JD025753>.
In gene-expression microarray studies, for example, one generally obtains a list of dozens or hundreds of genes that differ in expression between samples and then asks What does all of this mean biologically? Alternatively, gene lists can be derived conceptually in addition to experimentally. For instance, one might want to analyze a group of genes known as housekeeping genes. The work of the Gene Ontology (GO) Consortium <geneontology.org> provides a way to address that question. GO organizes genes into hierarchical categories based on biological process, molecular function and subcellular localization. The role of GoMiner is to automate the mapping between a list of genes and GO, and to provide a statistical summary of the results as well as a visualization.
This package provides a series of aliases to commonly used but difficult to remember ggplot2 sequences.
Simulation tool to facilitate determination of required sample size to achieve category saturation for studies using multiple repertory grids in conjunction with content analysis.
Datasets analysed in the book Antony Unwin (2024, ISBN:978-0367674007) "Getting (more out of) Graphics".
This package provides a comprehensive suite of genome-wide association study (GWAS) methods specifically designed for biobank-scale data, including but not limited to, robust approaches for time-to-event traits (Li et al., 2025 <doi:10.1038/s43588-025-00864-z>) and ordinal categorical traits (Bi et al., 2021 <doi:10.1016/j.ajhg.2021.03.019>). The package also offers general frameworks for GWAS of any trait type (Bi et al., 2020 <doi:10.1016/j.ajhg.2020.06.003>), while accounting for sample relatedness (Xu et al., 2025 <doi:10.1038/s41467-025-56669-1>) or population structure (Ma et al., 2025 <doi:10.1186/s13059-025-03827-9>). By accurately approximating score statistic distributions using saddlepoint approximation (SPA), these methods can effectively control type I error rates for rare variants and in the presence of unbalanced phenotype distributions. Additionally, the package includes functions for simulating genotype and phenotype data to support research and method development.
Reference datasets commonly used in the geosciences. These include standard atomic weights of the elements, a periodic table, a list of minerals including their abbreviations and chemistry, geochemical data of reservoirs (primitive mantle, continental crust, mantle, basalts, etc.), decay constants and isotopic ratios frequently used in geochronology, color codes of the chronostratigraphic chart. In addition, the package provides functions for basic queries of atomic weights, the list of minerals, and chronostratigraphic chart colors. All datasets are fully referenced, and a BibTeX file containing the references is included.
This package implements statistical methods for group factor analysis, focusing on estimating the number of global and local factors and extracting them. Several algorithms are implemented, including Canonical Correlation-based Estimation by Choi et al. (2021) <doi:10.1016/j.jeconom.2021.09.008>, Generalised Canonical Correlation Estimation by Lin and Shin (2023) <doi:10.2139/ssrn.4295429>, Circularly Projected Estimation by Chen (2022) <doi:10.1080/07350015.2022.2051520>, and the Aggregated Projection Method by Hu et al. (2025) <doi:10.1080/01621459.2025.2491154>.
This package contains functions to create life history parameter plots from raw data. The plots are created using ggplot2', and calculations done using the tidyverse collection of packages. The package contains references to FishBase (Froese R., Pauly D., 2023) <https://www.fishbase.se/>.
Gaussian process regression models, a.k.a. Kriging models, are applied to global multi-objective optimization of black-box functions. Multi-objective Expected Improvement and Step-wise Uncertainty Reduction sequential infill criteria are available. A quantification of uncertainty on Pareto fronts is provided using conditional simulations.
Estimates grid type bivariate copula functions, calculates some association measures and provides several copula graphics.
Implementation of a common set of punctual solutions for Cooperative Game Theory.
Set of routines for making map projections (forward and inverse), topographic maps, perspective plots, geological maps, geological map symbols, geological databases, interactive plotting and selection of focus regions.