The Gene Ontology (GO) Consortium <https://geneontology.org/> organizes genes into hierarchical categories based on biological process (BP), molecular function (MF) and cellular component (CC, i.e., subcellular localization). Tools such as GoMiner (see Zeeberg, B.R., Feng, W., Wang, G. et al. (2003) <doi:10.1186/gb-2003-4-4-r28>) can leverage GO to perform ontological analysis of microarray and proteomics studies, typically generating a list of significant functional categories. The significance is traditionally determined by randomizing the input gene list to computing the false discovery rate (FDR) of the enrichment p-value for each category. We explore here the novel alternative of randomizing the GO database rather than the gene list.

This package provides a collection of HTML', JavaScript', CSS and fonts assets that generate RapiDoc documentation from an OpenAPI Specification: <https://mrin9.github.io/RapiDoc/>.

Create an R Journal Rmarkdown template article, that will generate html and pdf versions of your paper. Check that the paper folder has all the required components needed for submission. Examples of R Journal publications can be found at <https://journal.r-project.org>.

This package provides the hybrid Bayesian method Geometric Density Estimation. On the one hand, it scales the dimension of our data, on the other it performs inference. The method is fully described in the paper "Scalable Geometric Density Estimation" by Y. Wang, A. Canale, D. Dunson (2016) <http://proceedings.mlr.press/v51/wang16e.pdf>.

Computationally efficient tool for performing variable selection and obtaining robust estimates, which implements robust variable selection procedure proposed by Wang, X., Jiang, Y., Wang, S., Zhang, H. (2013) <doi:10.1080/01621459.2013.766613>. Users can enjoy the near optimal, consistent, and oracle properties of the procedures.

This package contains convenience functions for working with spatial data across multiple UTM zones, raster-vector operations common in the analysis of conflict data, and converting degrees, minutes, and seconds latitude and longitude coordinates to decimal degrees.

Rectangle packing is a packing problem where rectangles are placed into a larger rectangular region (without overlapping) in order to maximise the use space. Rectangles are packed using the skyline heuristic as discussed in Lijun et al (2011) A Skyline-Based Heuristic for the 2D Rectangular Strip Packing Problem <doi:10.1007/978-3-642-21827-9_29>. A function is also included for determining a good small-sized box for containing a given set of rectangles.

This package performs model-free reinforcement learning in R. This implementation enables the learning of an optimal policy based on sample sequences consisting of states, actions and rewards. In addition, it supplies multiple predefined reinforcement learning algorithms, such as experience replay. Methodological details can be found in Sutton and Barto (1998) <ISBN:0262039249>.

We provide a number of algorithms to estimate fundamental statistics including Fréchet mean and geometric median for manifold-valued data. Also, C++ header files are contained that implement elementary operations on manifolds such as Sphere, Grassmann, and others. See Bhattacharya and Bhattacharya (2012) <doi:10.1017/CBO9781139094764> if you are interested in statistics on manifolds, and Absil et al (2007, ISBN:9780691132983) on computational aspects of optimization on matrix manifolds.

Based on data of real user-agent strings, we can set filtering conditions and randomly sample user-agent strings from the user-agent string pool.

This package provides a function to plot a regression nomogram of regression objects. Covariate distributions are superimposed on nomogram scales and the plot can be animated to allow on-the-fly changes to distribution representation and to enable outcome calculation.

Computes a novel variable importance for random forests: Impurity reduction importance scores for out-of-bag (OOB) data complementing the existing inbag Gini importance, see also <doi: 10.1080/03610926.2020.1764042>. The Gini impurities for inbag and OOB data are combined in three different ways, after which the information gain is computed at each split. This gain is aggregated for each split variable in a tree and averaged across trees.

This package provides a thin wrapper around the tiktoken-rs crate, allowing to encode text into Byte-Pair-Encoding (BPE) tokens and decode tokens back to text. This is useful to understand how Large Language Models (LLMs) perceive text.

Access to Boost Date_Time functionality for dates, durations (both for days and date time objects), time zones, and posix time ('ptime') is provided by using Rcpp modules'. The posix time implementation can support high-resolution of up to nano-second precision by using 96 bits (instead of 64 with R) to present a ptime object (but this needs recompilation with a #define set).

This package provides functions to implement the parametric and non-parametric bootstrap confidence interval methods described in Morrison and Simon (2017) <arXiv:1702.06986>.

Estimates life tables, specifically (crude) death rates and (raw and graduated) death probabilities, using rolling windows in one (e.g., age), two (e.g., age and time) or three (e.g., age, time and income) dimensions. The package can also be utilised for summarising statistics and smoothing continuous variables through rolling windows in other domains, such as estimating averages of self-positioning ideology in political science. Acknowledgements: The authors wish to thank Ministerio de Ciencia, Innovación y Universidades (grant PID2021-128228NB-I00) and Generalitat Valenciana (grants HIECPU/2023/2, Conselleria de Hacienda, Economà a y Administración Pública, and CIGE/2023/7, Conselleria de Educación, Cultura, Universidades y Empleo) for supporting this research.

This package provides reference classes implementing some useful data structures. The package implements these data structures by using the reference class R6. Therefore, the classes of the data structures are also reference classes which means that their instances are passed by reference. The implemented data structures include stack, queue, double-ended queue, doubly linked list, set, dictionary and binary search tree. See for example <https://en.wikipedia.org/wiki/Data_structure> for more information about the data structures.

Solves the individual bioenergetic balance for different aquaculture sea fish (Sea Bream and Sea Bass; Brigolin et al., 2014 <doi:10.3354/aei00093>) and shellfish (Mussel and Clam; Brigolin et al., 2009 <doi:10.1016/j.ecss.2009.01.029>; Solidoro et al., 2000 <doi:10.3354/meps199137>). Allows for spatialized model runs and population simulations.

Matrix reconstruction, also known as matrix completion, is the task of inferring missing entries of a partially observed matrix. This package provides a method called OptSpace, which was proposed by Keshavan, R.H., Oh, S., and Montanari, A. (2009) <doi:10.1109/ISIT.2009.5205567> for a case under low-rank assumption.

This package provides a collection of randomization tests, data sets and examples. The current version focuses on five testing problems and their implementation in empirical work. First, it facilitates the empirical researcher to test for particular hypotheses, such as comparisons of means, medians, and variances from k populations using robust permutation tests, which asymptotic validity holds under very weak assumptions, while retaining the exact rejection probability in finite samples when the underlying distributions are identical. Second, the description and implementation of a permutation test for testing the continuity assumption of the baseline covariates in the sharp regression discontinuity design (RDD) as in Canay and Kamat (2018) <https://goo.gl/UZFqt7>. More specifically, it allows the user to select a set of covariates and test the aforementioned hypothesis using a permutation test based on the Cramer-von Misses test statistic. Graphical inspection of the empirical CDF and histograms for the variables of interest is also supported in the package. Third, it provides the practitioner with an effortless implementation of a permutation test based on the martingale decomposition of the empirical process for testing for heterogeneous treatment effects in the presence of an estimated nuisance parameter as in Chung and Olivares (2021) <doi:10.1016/j.jeconom.2020.09.015>. Fourth, this version considers the two-sample goodness-of-fit testing problem under covariate adaptive randomization and implements a permutation test based on a prepivoted Kolmogorov-Smirnov test statistic. Lastly, it implements an asymptotically valid permutation test based on the quantile process for the hypothesis of constant quantile treatment effects in the presence of an estimated nuisance parameter.

Fetches NCBI data (RefSeq <https://www.ncbi.nlm.nih.gov/refseq/> database) and provides an environment to extract information at the level of gene, mRNA or protein accessions.

Provide a simple interface to Bloomberg's OpenFIGI API. Please see <https://openfigi.com> for API details and registration. You may be eligible to have an API key to accelerate your loading process.

Connects dataframes/tables with a remote data source. Raw data downloaded from the data source can be further processed and transformed using data preparation code that is also baked into the dataframe/table. Refreshable dataframes can be shared easily (e.g. as R data files). Their users do not need to care about the inner workings of the data update mechanisms.

Simple, easy to use, and flexible functionality for recoding variables. It allows for simple piecewise definition of transformations.