An automatic cluster-based annotation pipeline based on evidence-based score by matching the marker genes with known cell markers in tissue-specific cell taxonomy reference database for single-cell RNA-seq data. See Shao X, et al (2020) <doi:10.1016/j.isci.2020.100882> for more details.

Fits bi-variate ellipses to stable isotope data using Bayesian inference with the aim being to describe and compare their isotopic niche.

Interactively play a game of sokoban ,which has nine game levels.Sokoban is a type of transport puzzle, in which the player pushes boxes or crates around in a warehouse, trying to get them to storage locations.

Recently, regularized variable selection has emerged as a powerful tool to identify and dissect gene-environment interactions. Nevertheless, in longitudinal studies with high dimensional genetic factors, regularization methods for GÃ E interactions have not been systematically developed. In this package, we provide the implementation of sparse group variable selection, based on both the quadratic inference function (QIF) and generalized estimating equation (GEE), to accommodate the bi-level selection for longitudinal GÃ E studies with high dimensional genomic features. Alternative methods conducting only the group or individual level selection have also been included. The core modules of the package have been developed in C++.

Manage package documentation and namespaces from the command line. Programmatically attach namespaces in R and Rmd script, populates Roxygen2 skeletons with information scraped from within functions and populate the Imports field of the DESCRIPTION file.

This package provides a dynamic model of the big-picture, whole ecosystem effects of hydrodynamics, temperature, nutrients, and fishing on continental shelf marine food webs. The package is described in: Heath, M.R., Speirs, D.C., Thurlbeck, I. and Wilson, R.J. (2020) <doi:10.1111/2041-210X.13510> StrathE2E2: An R package for modelling the dynamics of marine food webs and fisheries. 8pp.

C++ classes for sparse matrix methods including implementation of sparse LDL decomposition of symmetric matrices and solvers described by Timothy A. Davis (2016) <https://fossies.org/linux/SuiteSparse/LDL/Doc/ldl_userguide.pdf>. Provides a set of C++ classes for basic sparse matrix specification and linear algebra, and a class to implement sparse LDL decomposition and solvers. See <https://github.com/samuel-watson/SparseChol> for details.

Gain seamless access to origin-destination (OD) data from the Spanish Ministry of Transport, hosted at <https://www.transportes.gob.es/ministerio/proyectos-singulares/estudios-de-movilidad-con-big-data/opendata-movilidad>. This package simplifies the management of these large datasets by providing tools to download zone boundaries, handle associated origin-destination data, and process it efficiently with the duckdb database interface. Local caching minimizes repeated downloads, streamlining workflows for researchers and analysts. Methods described in Kotov et al. (2026) <doi:10.1177/23998083251415040>. Extensive documentation is available at <https://ropenspain.github.io/spanishoddata/index.html>, offering guides on creating static and dynamic mobility flow visualizations and transforming large datasets into analysis-ready formats.

This package provides tools developed to facilitate the establishment of the rank and social hierarchy for gregarious animals by the Si method developed by Kondo & Hurnik (1990)<doi:10.1016/0168-1591(90)90125-W>. It is also possible to determine the number of agonistic interactions between two individuals, sociometric and dyadics matrix from dataset obtained through electronic bins. In addition, it is possible plotting the results using a bar plot, box plot, and sociogram.

Datasets for the textbook Stat2: Modeling with Regression and ANOVA (second edition). The package also includes data for the first edition, Stat2: Building Models for a World of Data and a few functions for plotting diagnostics.

Fits semiparametric linear and multilevel models with non-parametric additive Bayesian additive regression tree (BART; Chipman, George, and McCulloch (2010) <doi:10.1214/09-AOAS285>) components and Stan (Stan Development Team (2021) <https://mc-stan.org/>) sampled parametric ones. Multilevel models can be expressed using lme4 syntax (Bates, Maechler, Bolker, and Walker (2015) <doi:10.18637/jss.v067.i01>).

This package implements an ensemble machine learning approach to predict the sporulation potential of metagenome-assembled genomes (MAGs) from uncultivated Firmicutes based on the presence/absence of sporulation-associated genes.

This package implements the SPCAvRP algorithm, developed and analysed in "Sparse principal component analysis via random projections" Gataric, M., Wang, T. and Samworth, R. J. (2018) <arXiv:1712.05630>. The algorithm is based on the aggregation of eigenvector information from carefully-selected random projections of the sample covariance matrix.

This package implements the S-type estimators, novel robust estimators for general linear regression models, addressing challenges such as outlier contamination and leverage points. This package introduces robust regression techniques to provide a robust alternative to classical methods and includes diagnostic tools for assessing model fit and performance. The methodology is based on the study, "Comparison of the Robust Methods in the General Linear Regression Model" by Sazak and Mutlu (2023). This package is designed for statisticians and applied researchers seeking advanced tools for robust regression analysis.

This package provides methods for statistical disclosure control in tabular data such as primary and secondary cell suppression as described for example in Hundepol et al. (2012) <doi:10.1002/9781118348239> are covered in this package.

This package provides functions that compute the spatial covariance matrix for the matern and power classes of spatial models, for data that arise on rectangular units. This code can also be used for the change of support problem and for spatial data that arise on irregularly shaped regions like counties or zipcodes by laying a fine grid of rectangles and aggregating the integrals in a form of Riemann integration.

Spatial model calculation for static and dynamic panel data models, weights matrix creation and Bayesian model comparison. Bayesian model comparison methods were described by LeSage (2014) <doi:10.1016/j.spasta.2014.02.002>. The Lee'-'Yu transformation approach is described in Yu', De Jong and Lee (2008) <doi:10.1016/j.jeconom.2008.08.002>, Lee and Yu (2010) <doi:10.1016/j.jeconom.2009.08.001> and Lee and Yu (2010) <doi:10.1017/S0266466609100099>.

This package implements an approach aimed at assessing the accuracy and effectiveness of raw scores obtained in scales that contain locally dependent items. The program uses as input the calibration (structural) item estimates obtained from fitting extended unidimensional factor-analytic solutions in which the existing local dependencies are included. Measures of reliability (Omega) and information are proposed at three levels: (a) total score, (b) bivariate-doublet, and (c) item-by-item deletion, and are compared to those that would be obtained if all the items had been locally independent. All the implemented procedures can be obtained from: (a) linear factor-analytic solutions in which the item scores are treated as approximately continuous, and (b) non-linear solutions in which the item scores are treated as ordered-categorical. A detailed guide can be obtained at the following url.

Parametric survival regression models under the maximum likelihood approach via Stan'. Implemented regression models include accelerated failure time models, proportional hazards models, proportional odds models, accelerated hazard models, Yang and Prentice models, and extended hazard models. Available baseline survival distributions include exponential, Weibull, log-normal, log-logistic, gamma, generalized gamma, rayleigh, Gompertz and fatigue (Birnbaum-Saunders) distributions. References: Lawless (2002) <ISBN:9780471372158>; Bennett (1982) <doi:10.1002/sim.4780020223>; Chen and Wang(2000) <doi:10.1080/01621459.2000.10474236>; Demarqui and Mayrink (2021) <doi:10.1214/20-BJPS471>.

Implementation of statistical methods for the estimation of toroidal diffusions. Several diffusive models are provided, most of them belonging to the Langevin family of diffusions on the torus. Specifically, the wrapped normal and von Mises processes are included, which can be seen as toroidal analogues of the Ornstein-Uhlenbeck diffusion. A collection of methods for approximate maximum likelihood estimation, organized in four blocks, is given: (i) based on the exact transition probability density, obtained as the numerical solution to the Fokker-Plank equation; (ii) based on wrapped pseudo-likelihoods; (iii) based on specific analytic approximations by wrapped processes; (iv) based on maximum likelihood of the stationary densities. The package allows the replicability of the results in Garcà a-Portugués et al. (2019) <doi:10.1007/s11222-017-9790-2>.

This package provides a pipeline to perform small area estimation and prevalence mapping of binary indicators using health and demographic survey data, described in Fuglstad et al. (2022) <doi:10.48550/arXiv.2110.09576> and Wakefield et al. (2020) <doi:10.1111/insr.12400>.

The user has the option to utilize the two-dimensional density estimation techniques called smoothed density published by Eilers and Goeman (2004) <doi:10.1093/bioinformatics/btg454>, and pareto density which was evaluated for univariate data by Thrun, Gehlert and Ultsch, 2020 <doi:10.1371/journal.pone.0238835>. Moreover, it provides visualizations of the density estimation in the form of two-dimensional scatter plots in which the points are color-coded based on increasing density. Colors are defined by the one-dimensional clustering technique called 1D distribution cluster algorithm (DDCAL) published by Lux and Rinderle-Ma (2023) <doi:10.1007/s00357-022-09428-6>.

An implementation of split-population duration regression models. Unlike regular duration models, split-population duration models are mixture models that accommodate the presence of a sub-population that is not at risk for failure, e.g. cancer patients who have been cured by treatment. This package implements Weibull and Loglogistic forms for the duration component, and focuses on data with time-varying covariates. These models were originally formulated in Boag (1949) and Berkson and Gage (1952), and extended in Schmidt and Witte (1989).

Small area estimation unit level models (Battese-Harter-Fuller model) with a Bayesian Hierarchical approach. See also Rao & Molina (2015, ISBN:978-1-118-73578-7) and Battese et al. (1988) <doi:10.1080/01621459.1988.10478561>.