Allows for production of Czekanowski's Diagrams with clusters. See K. Bartoszek, A. Vasterlund (2020) <doi:10.2478/bile-2020-0008> and K. Bartoszek, Y. Luo (2023) <doi:10.14708/ma.v51i2.7259>. The suggested FuzzyDBScan package (which allows for fuzzy clustering) can be obtained from <https://github.com/henrifnk/FuzzyDBScan/> (or from CRAN's Archive <https://cran.r-project.org/src/contrib/Archive/FuzzyDBScan/>).

The significance of mean difference tests in clinical trials is established if at least r null hypotheses are rejected among m that are simultaneously tested. This package enables one to compute necessary sample sizes for single-step (Bonferroni) and step-wise procedures (Holm and Hochberg). These three procedures control the q-generalized family-wise error rate (probability of making at least q false rejections). Sample size is computed (for these single-step and step-wise procedures) in a such a way that the r-power (probability of rejecting at least r false null hypotheses, i.e. at least r significant endpoints among m) is above some given threshold, in the context of tests of difference of means for two groups of continuous endpoints (variables). Various types of structure of correlation are considered. It is also possible to analyse data (i.e., actually test difference in means) when these are available. The case r equals 1 is treated in separate functions that were used in Lafaye de Micheaux et al. (2014) <doi:10.1080/10543406.2013.860156>.

Wraps some of the matrix exponentiation utilities from EXPOKIT (<http://www.maths.uq.edu.au/expokit/>), a FORTRAN library that is widely recommended for matrix exponentiation (Sidje RB, 1998. "Expokit: A Software Package for Computing Matrix Exponentials." ACM Trans. Math. Softw. 24(1): 130-156). EXPOKIT includes functions for exponentiating both small, dense matrices, and large, sparse matrices (in sparse matrices, most of the cells have value 0). Rapid matrix exponentiation is useful in phylogenetics when we have a large number of states (as we do when we are inferring the history of transitions between the possible geographic ranges of a species), but is probably useful in other ways as well. NOTE: In case FORTRAN checks temporarily get rexpokit archived on CRAN, see archived binaries at GitHub in: nmatzke/Matzke_R_binaries (binaries install without compilation of source code).

Uses a combination of raytracing and multiple hill shading methods to produce 2D and 3D data visualizations and maps. Includes water detection and layering functions, programmable color palette generation, several built-in textures for hill shading, 2D and 3D plotting options, a built-in path tracer, Wavefront OBJ file export, and the ability to save 3D visualizations to a 3D printable format.

Quantitative Structure-Activity Relationship (QSAR) modeling is a valuable tool in computational chemistry and drug design, where it aims to predict the activity or property of chemical compounds based on their molecular structure. In this vignette, we present the rQSAR package, which provides functions for variable selection and QSAR modeling using Multiple Linear Regression (MLR), Partial Least Squares (PLS), and Random Forest algorithms.

Interoperability between Rcpp and the C++11 array and tuple types. Linking to this package allows fixed-length std::array objects to be converted to and from equivalent R vectors, and std::tuple objects converted to lists, via the as() and wrap() functions. There is also experimental support for std::span from C++20'.

This package provides functions for reading data sets in different formats for testing machine learning tools are provided. This allows to run a loop over several data sets in their original form, for example if they are downloaded from UCI Machine Learning Repository. The data are not part of the package and have to be downloaded separately.

This package provides a tool to calculate Cardiovascular Risk Scores in large data frames as published in Perez-Vicencio, et al (2024) <doi:10.1136/openhrt-2024-002755>. Cardiovascular risk scores are statistical tools used to assess an individual's likelihood of developing a cardiovascular disease based on various risk factors, such as age, gender, blood pressure, cholesterol levels, and smoking. Here we bring together the six most commonly used in the emergency department. Using RiskScorescvd', you can calculate all the risk scores in an extended dataset in seconds. PCE (ASCVD) described in Goff, et al (2013) <doi:10.1161/01.cir.0000437741.48606.98>. EDACS described in Mark DG, et al (2016) <doi:10.1016/j.jacc.2017.11.064>. GRACE described in Fox KA, et al (2006) <doi:10.1136/bmj.38985.646481.55>. HEART is described in Mahler SA, et al (2017) <doi:10.1016/j.clinbiochem.2017.01.003>. SCORE2/OP described in SCORE2 working group and ESC Cardiovascular risk collaboration (2021) <doi:10.1093/eurheartj/ehab309>. TIMI described in Antman EM, et al (2000) <doi:10.1001/jama.284.7.835>. SCORE2-Diabetes described in SCORE2-Diabetes working group and ESC Cardiovascular risk collaboration (2023) <doi:10.1093/eurheartj/ehab260>. SCORE2/OP with CKD add-on described in Kunihiro M et al (2022) <doi:10.1093/eurjpc/zwac176>.

Makes documents containing plots and tables from a table of R codes. Can make "HTML", "pdf('LaTex')", "docx('MS Word')" and "pptx('MS Powerpoint')" documents with or without R code. In the package, modularized shiny app codes are provided. These modules are intended for reuse across applications.

This package provides tools to manipulate and visualize graphs (networks) for computational biology in drug discovery, for instance functions for creating bipartite graphs and for interactive visualizations. Zhang (2025) <https://github.com/bedapub/ribiosGraph>.

IUCN Red List (<https://api.iucnredlist.org/>) client. The IUCN Red List is a global list of threatened and endangered species. Functions cover all of the Red List API routes. An API key is required.

Evaluates R source codes by variable and/or functions names. Similar source codes should deliver similarity coefficients near one. Since neither the frequency nor the order of the used names is considered, a manual inspection of the R source code is required to check for similarity. Possible use cases include detection of code clones for improving software quality and of plagiarism amongst students assignments.

External jars required for package RWeka'.

Includes algorithms to assess research productivity and patterns, such as the h-index and i-index. Cardoso et al. (2022) Cardoso, P., Fukushima, C.S. & Mammola, S. (2022) Quantifying the internationalization and representativeness in research. Trends in Ecology and Evolution, 37: 725-728.

Implementations for several robust procedures that allow for (online) extraction of the signal of univariate or multivariate time series by applying robust regression techniques to a moving time window are provided. Included are univariate filtering procedures based on repeated-median regression as well as hybrid and trimmed filters derived from it; see Schettlinger et al. (2006) <doi:10.1515/BMT.2006.010>. The adaptive online repeated median by Schettlinger et al. (2010) <doi:10.1002/acs.1105> and the slope comparing adaptive repeated median by Borowski and Fried (2013) <doi:10.1007/s11222-013-9391-7> choose the width of the moving time window adaptively. Multivariate versions are also provided; see Borowski et al. (2009) <doi:10.1080/03610910802514972> for a multivariate online adaptive repeated median and Borowski (2012) <doi:10.17877/DE290R-14393> for a multivariate slope comparing adaptive repeated median. Furthermore, a repeated-median based filter with automatic outlier replacement and shift detection is provided; see Fried (2004) <doi:10.1080/10485250410001656444>.

This package provides tools for downloading and analyzing CDC NHANES data, with a focus on analytical laboratory data.

This package provides a programmatic interface to the Web Service methods provided by ITALIC (<https://italic.units.it>). ITALIC is a database of lichen data in Italy and bordering European countries. ritalic includes functions for retrieving information about lichen scientific names, geographic distribution, ecological data, morpho-functional traits and identification keys. More information about the data is available at <https://italic.units.it/?procedure=base&t=59&c=60>. The API documentation is available at <https://italic.units.it/?procedure=api>.

Implementation of corrected two-sample tests. A corrected version of the Pearson and Kendall correlation tests, the Mann-Whitney (Wilcoxon) rank sum test, the Wilcoxon signed rank test and a variance test are implemented. The package also proposes a test for the median and an independence test between two continuous variables of Kolmogorov-Smirnov's type. All these corrected tests are asymptotically calibrated in the sense that the probability of rejection under the null hypothesis is asymptotically equal to the level of the test. See <doi:10.48550/arXiv.2211.08784> for more details on the statistical tests.

Robust parameter estimation and prediction of Gaussian stochastic process emulators. It allows for robust parameter estimation and prediction using Gaussian stochastic process emulator. It also implements the parallel partial Gaussian stochastic process emulator for computer model with massive outputs See the reference: Mengyang Gu and Jim Berger, 2016, Annals of Applied Statistics; Mengyang Gu, Xiaojing Wang and Jim Berger, 2018, Annals of Statistics.

Despite the predominant use of R for data manipulation and various robust statistical calculations, in recent years, more people from various disciplines are beginning to use R for other purposes. In doing this seemlessly, further tools are needed users to easily and freely write in R for all kinds of purposes. The r2dictionary introduces a means for users to directly search for definitions of terms within the R environment.

Processing and analysis of targeted sequencing data. The package provides a user-friendly interface for core VSEARCH (Rognes et al. (2016), <doi:10.7717/peerj.2584>) functions, in addition to tools for visualization and parameter tuning.

This package provides a random-effects stochastic model that allows quick detection of clonal dominance events from clonal tracking data collected in gene therapy studies. Starting from the Ito-type equation describing the dynamics of cells duplication, death and differentiation at clonal level, we first considered its local linear approximation as the base model. The parameters of the base model, which are inferred using a maximum likelihood approach, are assumed to be shared across the clones. Although this assumption makes inference easier, in some cases it can be too restrictive and does not take into account possible scenarios of clonal dominance. Therefore we extended the base model by introducing random effects for the clones. In this extended formulation the dynamic parameters are estimated using a tailor-made expectation maximization algorithm. Further details on the methods can be found in L. Del Core et al., (2022) <doi:10.1101/2022.05.31.494100>.

The Diceware method can be used to generate strong passphrases. In short, you roll a 6-faced dice 5 times in a row, the number obtained is matched against a dictionary of easily remembered words. By combining together 7 words thus generated, you obtain a password that is relatively easy to remember, but would take several millions years (on average) for a powerful computer to guess.

Downloads, imports, and tidies time series data from the Australian Bureau of Statistics <https://www.abs.gov.au/>.