An implementation of a method based on information theory devised for the identification of genes showing a significant variation of expression across multiple conditions. Given expression estimates from any number of RNA-Seq samples and conditions it identifies genes or transcripts with a significant variation of expression across all the conditions studied, together with the samples in which they are over- or under-expressed. Zambelli et al. (2018) <doi:10.1093/nar/gky055>.

R parallel implementation of Local Outlier Factor(LOF) which uses multiple CPUs to significantly speed up the LOF computation for large datasets. (Note: The overall performance depends on the computers especially the number of the cores).It also supports multiple k values to be calculated in parallel, as well as various distance measures in addition to the default Euclidean distance.

This package provides data processing and summarization of data from FishNet2.net in text and graphical outputs. Allows efficient filtering of information and data cleaning.

Encrypt R objects to a raw vector or file using modern cryptographic techniques. Password-based key derivation is with Argon2 (<https://en.wikipedia.org/wiki/Argon2>). Objects are serialized and then encrypted using XChaCha20-Poly1305 (<https://en.wikipedia.org/wiki/ChaCha20-Poly1305>) which follows RFC 8439 for authenticated encryption (<https://en.wikipedia.org/wiki/Authenticated_encryption>). Cryptographic functions are provided by the included monocypher C library (<https://monocypher.org>).

Generates a project and repo for easy initialization of a GitHub repo for R workshops. The repo includes a README with instructions to ensure that all users have the needed packages, an RStudio project with the right directories and the proper data. The repo can then be used for hosting code taught during the workshop.

This package provides an R interface to the NiftyReg image registration tools <https://github.com/KCL-BMEIS/niftyreg>. Linear and nonlinear registration are supported, in two and three dimensions.

Designed for longitudinal data analysis using Hidden Markov Models (HMMs). Tailored for applications in healthcare, social sciences, and economics, the main emphasis of this package is on regularization techniques for fitting HMMs. Additionally, it provides an implementation for fitting HMMs without regularization, referencing Zucchini et al. (2017, ISBN:9781315372488).

We visualize the standard deviation of a data set as the radius of a cylinder whose volume equals the total volume of several cylinders made by revolving the empirical cumulative distribution function about the vertical line through the mean. For more details see Sarkar and Rashid (2016) <doi:10.1080/00031305.2016.1165734>.

Imputation of missing numerical outcomes for a longitudinal trial with protocol deviations. The package uses distinct treatment arm-based assumptions for the unobserved data, following the general algorithm of Carpenter, Roger, and Kenward (2013) <doi:10.1080/10543406.2013.834911>, and the causal model of White, Royes and Best (2020) <doi:10.1080/10543406.2019.1684308>. Sensitivity analyses to departures from these assumptions can be done by the Delta method of Roger. The program uses the same algorithm as the mimix Stata package written by Suzie Cro, with additional coding for the causal model and delta method. The reference-based methods are jump to reference (J2R), copy increments in reference (CIR), copy reference (CR), and the causal model, all of which must specify the reference treatment arm. Other methods are missing at random (MAR) and the last mean carried forward (LMCF). Individual-specific imputation methods (and their reference groups) can be specified.

This package provides a simple data science challenge system using R Markdown and Dropbox <https://www.dropbox.com/>. It requires no network configuration, does not depend on external platforms like e.g. Kaggle <https://www.kaggle.com/> and can be easily installed on a personal computer.

This package provides a machine learning package for automatic text classification that makes it simple for novice users to get started with machine learning, while allowing experienced users to easily experiment with different settings and algorithm combinations. The package includes eight algorithms for ensemble classification (svm, slda, boosting, bagging, random forests, glmnet, decision trees, neural networks), comprehensive analytics, and thorough documentation.

Minimally adjust the values of numerical records in a data.frame, such that each record satisfies a predefined set of equality and/or inequality constraints. The constraints can be defined using the validate package. The core algorithms have recently been moved to the lintools package, refer to lintools for a more basic interface and access to a version of the algorithm that works with sparse matrices.

Create plots and LaTeX tables that look like SPSS output for use in teaching materials. Rather than copying-and-pasting SPSS output into documents, R code that mocks up SPSS output can be integrated directly into dynamic LaTeX documents with tools such as knitr. Functionality includes statistical techniques that are typically covered in introductory statistics classes: descriptive statistics, common hypothesis tests, ANOVA, and linear regression, as well as box plots, histograms, scatter plots, and line plots (including profile plots).

This package provides functionality to prepare data and analyze plausibility of both forecasted and reported epidemiological signals. The functions implement a set of plausibility algorithms that are agnostic to geographic and time resolutions and are calculated independently then presented as a combined score.

This is a wrapper function for image(), which makes reasonable raster plots with nice axis and other useful features.

We provide functions to perform taxometric analyses. This package contains 46 functions, but only 5 should be called directly by users. CheckData() should be run prior to any taxometric analysis to ensure that the data are appropriate for taxometric analysis. RunTaxometrics() performs taxometric analyses for a sample of data. RunCCFIProfile() performs a series of taxometric analyses to generate a CCFI profile. CreateData() generates a sample of categorical or dimensional data. ClassifyCases() assigns cases to groups using the base-rate classification method.

The Google FarmHash family of hash functions is used by the Google BigQuery data warehouse via the FARM_FINGERPRINT function. This package permits to calculate these hash digest fingerprints directly from R, and uses the included FarmHash files written by G. Pike and copyrighted by Google, Inc.

Automatic, semi-automatic, and manual functions for generating color maps from images. The idea is to simplify the colors of an image according to a metric that is useful for the user, using deterministic methods whenever possible. Many images will be clustered well using the out-of-the-box functions, but the package also includes a toolbox of functions for making manual adjustments (layer merging/isolation, blurring, fitting to provided color clusters or those from another image, etc). Also includes export methods for other color/pattern analysis packages (pavo, patternize, colordistance).

Linear regression functions using Huber and bisquare psi functions. Optimal weights are calculated using IRLS algorithm.

Robustness -- eXperimental', eXtraneous', or eXtraordinary Functionality for Robust Statistics. Hence methods which are not well established, often related to methods in package robustbase'. Amazingly, BACON()', originally by Billor, Hadi, and Velleman (2000) <doi:10.1016/S0167-9473(99)00101-2> has become established in places. The "barrow wheel" `rbwheel()` is from Stahel and Mächler (2009) <doi:10.1111/j.1467-9868.2009.00706.x>.

This package provides a collection of functions related to the study of etiologic heterogeneity both across disease subtypes and across individual disease markers. The included functions allow one to quantify the extent of etiologic heterogeneity in the context of a case-control study, and provide p-values to test for etiologic heterogeneity across individual risk factors. Begg CB, Zabor EC, Bernstein JL, Bernstein L, Press MF, Seshan VE (2013) <doi:10.1002/sim.5902>.

Automatically flags common spatial errors in biological collection data using metadata and specialists information. RuHere implements a workflow to manage occurrence data through six steps: dataset merging, metadata flagging, validation against expert-derived distribution maps, visualization of flagged records, and sampling bias exploration. It specifically integrates specialist-curated range information to identify geographic errors and introductions that often escape standard automated validation procedures. For details on the methodology, see: Trindade & Caron (2026) <doi:10.64898/2026.02.02.703373>.

Takes matched and unmatched data and calculates Rosenbaum bounds for the treatment effect. Calculates bounds for binary outcome data, Hodges-Lehmann point estimates, Wilcoxon signed-rank test for matched data and matched IV estimators, Wilcoxon sum rank test, and for data with multiple matched controls. The sensitivity analysis methods in this package are documented in Rosenbaum (2002) Observational Studies, <doi:10.1007/978-1-4757-3692-2>, Springer-Verlag.

This package provides fast procedures for exploring all pairs of cutpoints of a single covariate with respect to survival and determining optimal cutpoints using a hierarchical method and various ordered logrank tests.