Dose Titration Algorithm Tuning (DTAT) is a methodologic framework allowing dose individualization to be conceived as a continuous learning process that begins in early-phase clinical trials and continues throughout drug development, on into clinical practice. This package includes code that researchers may use to reproduce or extend key results of the DTAT research programme, plus tools for trialists to design and simulate a 3+3/PC dose-finding study. Please see Norris (2017a) <doi:10.12688/f1000research.10624.3> and Norris (2017c) <doi:10.1101/240846>.

Basic routines used in scientific coding, such as timing routines, vector/array handing functions and I/O support routines.

Find, visualize and explore patterns of differential taxa in vegetation data (namely in a phytosociological table), using the Differential Value (DiffVal). Patterns are searched through mathematical optimization algorithms. Ultimately, Total Differential Value (TDV) optimization aims at obtaining classifications of vegetation data based on differential taxa, as in the traditional geobotanical approach (Monteiro-Henriques 2025, <doi:10.3897/VCS.140466>). The Gurobi optimizer, as well as the R package gurobi', can be installed from <https://www.gurobi.com/products/gurobi-optimizer/>. The useful vignette Gurobi Installation Guide, from package prioritizr', can be found here: <https://prioritizr.net/articles/gurobi_installation_guide.html>.

Allows humanitarian community, academia, media, government, and non-governmental organizations to utilize the data collected by the Displacement Tracking Matrix (<https://dtm.iom.int>), a unit in the International Organization for Migration. This also provides non-sensitive Internally Displaced Person figures, aggregated at the country, Admin 1 (states, provinces, or equivalent), and Admin 2 (smaller administrative areas) levels.

Visualizes variables from descriptive tables produced by descsuppR::buildDescrTbl() using ggstatsplot'. It automatically maps each variable to a suitable ggstatsplot plotting function based on the applied or suggested statistical test. Users can override the automatic mapping via a named list of plot specifications. The package supports grouped and ungrouped tables, and forwards additional arguments to the underlying ggstatsplot functions, providing quick, reproducible, and customizable default visualizations for descriptive summaries.

Identifies code blocks that have a high level of similarity within a set of R files.

Basic time series functionalities such as listing of missing values, application of arbitrary aggregation as well as rolling (asymmetric) window functions and automatic detection of periodicity. As it is mainly based on data.table', it is fast and (in combination with the R6 package) offers reference semantics. In addition to its native R6 interface, it provides an S3 interface for those who prefer the latter. Finally yet importantly, its functional approach allows for incorporating functionalities from many other packages.

Base DataSHIELD functions for the server side. DataSHIELD is a software package which allows you to do non-disclosive federated analysis on sensitive data. DataSHIELD analytic functions have been designed to only share non disclosive summary statistics, with built in automated output checking based on statistical disclosure control. With data sites setting the threshold values for the automated output checks. For more details, see citation("dsBase")'.

This package provides select, insert, update, upsert, and delete database operations. Supports PostgreSQL', MySQL', SQLite', and more, and plays nicely with the DBI package.

Simple feature stores and tools for creating personalised feature stores. diseasystore powers feature stores which can automatically link and aggregate features to a given stratification level. These feature stores are automatically time-versioned (powered by the SCDB package) and allows you to easily and dynamically compute features as part of your continuous integration.

Efficient Global Optimization (EGO) algorithm as described in "Roustant et al. (2012)" <doi:10.18637/jss.v051.i01> and adaptations for problems with noise ("Picheny and Ginsbourger, 2012") <doi:10.1016/j.csda.2013.03.018>, parallel infill, and problems with constraints.

Dynamic Reservoir Simulation Model (DYRESM) and Computational Aquatic Ecosystem Dynamics Model (CAEDYM) model development, including assisting with calibrating selected model parameters and visualising model output through time series plot, profile plot, contour plot, and scatter plot. For more details, see Yu et al. (2023) <https://journal.r-project.org/articles/RJ-2023-008/>.

Spatial downscaling of coarse grid mapping to fine grid mapping using predictive covariates and a model fitted using the caret package. The original dissever algorithm was published by Malone et al. (2012) <doi:10.1016/j.cageo.2011.08.021>, and extended by Roudier et al. (2017) <doi:10.1016/j.compag.2017.08.021>.

Data sets and sample analyses from Jay L. Devore (2008), "Probability and Statistics for Engineering and the Sciences (7th ed)", Thomson.

This package provides a function toolkit to facilitate reproducible RNA-Seq Differential Gene Expression (DGE) analysis (Law (2015) <doi:10.12688/f1000research.9005.3>). The tools include both analysis work-flow and utility functions: mapping/unit conversion, count normalization, accounting for unknown covariates, and more. This is a complement/cohort to the DGEobj package that provides a flexible container to manage and annotate Differential Gene Expression analysis results.

While autoregressive distributed lag (ARDL) models allow for extremely flexible dynamics, interpreting substantive significance of complex lag structures remains difficult. This package is designed to assist users in dynamically simulating and plotting the results of various ARDL models. It also contains post-estimation diagnostics, including a test for cointegration when estimating the error-correction variant of the autoregressive distributed lag model (Pesaran, Shin, and Smith 2001 <doi:10.1002/jae.616>).

This package provides tools for describing parameters of algorithms in an abstract way. Description can include an id, a description, a domain (range or list of values), and a default value. dynparam can also convert parameter sets to a ParamHelpers format, in order to be able to use dynparam in conjunction with mlrMBO'.

This package provides functions for discordant kinship modeling (and other sibling-based quasi-experimental designs). Contains data restructuring functions and functions for generating biometrically informed data for kin pairs. See [Garrison and Rodgers, 2016 <doi:10.1016/j.intell.2016.08.008>], [Sims, Trattner, and Garrison, 2024 <doi:10.3389/fpsyg.2024.1430978>] for empirical examples, and [Garrison and colleagues for theoretical work <doi:10.1101/2025.08.25.25334395>].

The natural increase in the complexity of current research experiments and data demands better tools to enhance productivity in Data Analytics. The package is a framework designed to address the modern challenges in data analytics workflows. The package is inspired by Experiment Line concepts. It aims to provide seamless support for users in developing their data mining workflows by offering a uniform data model and method API. It enables the integration of various data mining activities, including data preprocessing, classification, regression, clustering, and time series prediction. It also offers options for hyper-parameter tuning and supports integration with existing libraries and languages. Overall, the package provides researchers with a comprehensive set of functionalities for data science, promoting ease of use, extensibility, and integration with various tools and libraries. Information on Experiment Line is based on Ogasawara et al. (2009) <doi:10.1007/978-3-642-02279-1_20>.

This package provides a toolbox to create and manage metadata files and configuration profiles: files used to configure the parameters and initial settings for some computer programs.

Scripting of structural equation models via lavaan for Dyadic Data Analysis, and helper functions for supplemental calculations, tabling, and model visualization.

Distributed Online Goodness-of-Fit Test can process the distributed datasets. The philosophy of the package is described in Guo G.(2024) <doi:10.1016/j.apm.2024.115709>.

Implementing algorithms and fitting models when sites (possibly remote) share computation summaries rather than actual data over HTTP with a master R process (using opencpu', for example). A stratified Cox model and a singular value decomposition are provided. The former makes direct use of code from the R survival package. (That is, the underlying Cox model code is derived from that in the R survival package.) Sites may provide data via several means: CSV files, Redcap API, etc. An extensible design allows for new methods to be added in the future and includes facilities for local prototyping and testing. Web applications are provided (via shiny') for the implemented methods to help in designing and deploying the computations.

Curated datasets and intuitive data management functions to streamline epidemiological data workflows. It is designed to support researchers in quickly accessing clean, structured data and applying essential cleaning, summarizing, visualization, and export operations with minimal effort. Whether you're preparing a cohort for analysis or creating reports, DIVINE makes the process more efficient, transparent, and reproducible.