This package creates a data frame with the residuals of partial regressions of the main explanatory variable and the variable of interest. This method follows the Frisch-Waugh-Lovell theorem, as explained in Lovell (2008) <doi:10.3200/JECE.39.1.88-91>.

Implementation of PCMRS (Partial Credit Model with Response Styles) as proposed in by Tutz, Schauberger and Berger (2018) <doi:10.1177/0146621617748322> . PCMRS is an extension of the regular partial credit model. PCMRS allows for an additional person parameter that characterizes the response style of the person. By taking the response style into account, the estimates of the item parameters are less biased than in partial credit models.

This package provides a common problem faced by journal reviewers and authors is the question of whether the results of a replication study are consistent with the original published study. One solution to this problem is to examine the effect size from the original study and generate the range of effect sizes that could reasonably be obtained (due to random sampling) in a replication attempt (i.e., calculate a prediction interval). This package has functions that calculate the prediction interval for the correlation (i.e., r), standardized mean difference (i.e., d-value), and mean.

Dynamize headers or R code within Rmd files to prevent proliferation of Rmd files for similar reports. Add in external HTML document within rmarkdown rendered HTML doc.

Generates design matrix for analysing real paired comparisons and derived paired comparison data (Likert type items/ratings or rankings) using a loglinear approach. Fits loglinear Bradley-Terry model (LLBT) exploiting an eliminate feature. Computes pattern models for paired comparisons, rankings, and ratings. Some treatment of missing values (MCAR and MNAR). Fits latent class (mixture) models for paired comparison, rating and ranking patterns using a non-parametric ML approach.

This package provides functions for pooling/combining the results (i.e., p-values) from (dependent) hypothesis tests. Included are Fisher's method, Stouffer's method, the inverse chi-square method, the Bonferroni method, Tippett's method, and the binomial test. Each method can be adjusted based on an estimate of the effective number of tests or using empirically derived null distribution using pseudo replicates. For Fisher's, Stouffer's, and the inverse chi-square method, direct generalizations based on multivariate theory are also available (leading to Brown's method, Strube's method, and the generalized inverse chi-square method). An introduction can be found in Cinar and Viechtbauer (2022) <doi:10.18637/jss.v101.i01>.

This is a data-only package, containing data needed to run the CRAN package pathfindR', a package for enrichment analysis utilizing active subnetworks. This package contains protein-protein interaction network data, data related to gene sets and example input/output data.

Using the R package reticulate', this package creates an interface to the pysd toolset. The package provides an R interface to a number of pysd functions, and can read files in Vensim mdl format, and xmile format. The resulting simulations are returned as a tibble', and from that the results can be processed using dplyr and ggplot2'. The package has been tested using python3'.

Compute standard Non-Compartmental Analysis (NCA) parameters for typical pharmacokinetic analyses and summarize them.

Item response theory based methods are used to compute linking constants and conduct chain linking of unidimensional or multidimensional tests for multiple groups under a common item design. The unidimensional methods include the Mean/Mean, Mean/Sigma, Haebara, and Stocking-Lord methods for dichotomous (1PL, 2PL and 3PL) and/or polytomous (graded response, partial credit/generalized partial credit, nominal, and multiple-choice model) items. The multidimensional methods include the least squares method and extensions of the Haebara and Stocking-Lord method using single or multiple dilation parameters for multidimensional extensions of all the unidimensional dichotomous and polytomous item response models. The package also includes functions for importing item and/or ability parameters from common IRT software, conducting IRT true score and observed score equating, and plotting item response curves/surfaces, vector plots, information plots, and comparison plots for examining parameter drift.

Power logit regression models for bounded continuous data, in which the density generator may be normal, Student-t, power exponential, slash, hyperbolic, sinh-normal, or type II logistic. Diagnostic tools associated with the fitted model, such as the residuals, local influence measures, leverage measures, and goodness-of-fit statistics, are implemented. The estimation process follows the maximum likelihood approach and, currently, the package supports two types of estimators: the usual maximum likelihood estimator and the penalized maximum likelihood estimator. More details about power logit regression models are described in Queiroz and Ferrari (2022) <arXiv:2202.01697>.

This package provides tools for exchanging pedigree data between the pedsuite packages and the Familias software for forensic kinship computations (Egeland et al. (2000) <doi:10.1016/s0379-0738(00)00147-x>). These functions were split out from the forrel package to streamline maintenance and provide a lightweight alternative for packages otherwise independent of forrel'.

Paired mass distance (PMD) analysis proposed in Yu, Olkowicz and Pawliszyn (2018) <doi:10.1016/j.aca.2018.10.062> and PMD based reactomics analysis proposed in Yu and Petrick (2020) <doi:10.1038/s42004-020-00403-z> for gas/liquid chromatographyâ mass spectrometry (GC/LC-MS) based non-targeted analysis. PMD analysis including GlobalStd algorithm and structure/reaction directed analysis. GlobalStd algorithm could found independent peaks in m/z-retention time profiles based on retention time hierarchical cluster analysis and frequency analysis of paired mass distances within retention time groups. Structure directed analysis could be used to find potential relationship among those independent peaks in different retention time groups based on frequency of paired mass distances. Reactomics analysis could also be performed to build PMD network, assign sources and make biomarker reaction discovery. GUIs for PMD analysis is also included as shiny applications.

An interactive shiny application for Health Technology Assessment (HTA) parameter estimation. Converts between rates, probabilities, odds, and hazard ratios (HR); extrapolates survival curves (Exponential, Weibull, Log-Logistic); fits probabilistic sensitivity analysis (PSA) distributions (Beta, Gamma, LogNormal, Dirichlet) via the method of moments; calculates incremental cost-effectiveness ratios (ICERs), net monetary benefit (NMB), value-based pricing, and budget impact; adjusts costs for inflation, discounting, and purchasing power parity (PPP) across 30 countries; and adjusts background mortality using life-table methods. Designed for researchers building cost-effectiveness and budget-impact models who need auditable, formula-documented parameter transformations. Methods include Zhang and Yu (1998) <doi:10.1001/jama.280.19.1690> for odds ratio (OR) to relative risk (RR) conversion and Chinn (2000, Statistics in Medicine, 19, 3127-3131) for effect-size transformations.

Visualizes panel data. It has four main functionalities: (1) it plots the treatment status and missing values in a panel dataset; (2) it visualizes the temporal dynamics of a main variable of interest; (3) it depicts the bivariate relationships between a treatment variable and an outcome variable either by unit or in aggregate; (4) it displays the network structure of multi-way fixed effects as a k-partite graph, identifying connected components, singletons, and duplicate observations. For details, see <doi:10.18637/jss.v107.i07>.

Efficient algorithm for estimating piecewise exponential hazard models for right-censored data, and is useful for reliable power calculation, study design, and event/timeline prediction for study monitoring.

This package provides a user interface to create or modify pharmacometric models for various modeling and simulation software platforms.

Creation of patient profile visualizations for exploration, diagnostic or monitoring purposes during a clinical trial. These static visualizations display a patient-specific overview of the evolution during the trial time frame of parameters of interest (as laboratory, ECG, vital signs), presence of adverse events, exposure to a treatment; associated with metadata patient information, as demography, concomitant medication. The visualizations can be tailored for specific domain(s) or endpoint(s) of interest. Visualizations are exported into patient profile report(s) or can be embedded in custom report(s).

All PubChem compounds are downloaded to a local computer, but for each compound, only partial records are used. The data are organized into small files referenced by PubChem CID. This package also contains functions to parse the biologically relevant compounds from all PubChem compounds, using biological database sources, pathway presence, and taxonomic relationships. Taxonomy is used to generate a lowest common ancestor taxonomy ID (NCBI) for each biological metabolite, which then enables creation of taxonomically specific metabolome databases for any taxon.

Do Markov chain Monte Carlo (MCMC) simulation of Potts models (Potts, 1952, <doi:10.1017/S0305004100027419>), which are the multi-color generalization of Ising models (so, as as special case, also simulates Ising models). Use the Swendsen-Wang algorithm (Swendsen and Wang, 1987, <doi:10.1103/PhysRevLett.58.86>) so MCMC is fast. Do maximum composite likelihood estimation of parameters (Besag, 1975, <doi:10.2307/2987782>, Lindsay, 1988, <doi:10.1090/conm/080>).

Set of tools for reading, writing and transforming spatial and seasonal data, model selection and specific statistical tests for ecologists. It includes functions to interpolate regular positions of points between landmarks, to discretize polylines into regular point positions, link distant observations to points and convert a bounding box in a spatial object. It also provides miscellaneous functions for field ecologists such as spatial statistics and inference on diversity indexes, writing data.frame with Chinese characters.

This package provides methods for fitting point processes with parameters of generalised additive model (GAM) form are provided. For an introduction to point processes see Cox, D.R & Isham, V. (Point Processes, 1980, CRC Press), GAMs see Wood, S.N. (2017) <doi:10.1201/9781315370279>, and the fitting approach see Wood, S.N., Pya, N. & Safken, B. (2016) <doi:10.1080/01621459.2016.1180986>.

Imputes missing species trait data for comparative analyses by combining three sources of information: phylogenetic similarity (closely related species share similar traits), cross-trait correlations (observed traits inform missing ones), and optional environmental covariates (climate, habitat, geography). Handles continuous measurements, counts, binary variables, ordered categories, unordered categories, bounded proportions, zero-inflated counts, and compositional multi-proportion data in a single call. The method blends a phylogenetic baseline with a graph neural network correction; a per-trait gate calibrated on held-out data ensures the network only contributes when it improves on the baseline. Provides conformal prediction intervals for continuous, count, and ordinal traits and an experimental analysis-aware multiple-imputation workflow for one missing continuous covariate in Gaussian linear, binomial-logit, and Gaussian random-intercept models, with Rubin pooling limited to fixed effects. Stochastic graph-network and posterior-tree completions are prediction diagnostics rather than validated inferential imputations. Tested up to 10,000 species. Bundled datasets include 300-species and 9,993-species bird-trait subsets with matching example phylogenetic trees. Rubin (1987, ISBN:978-0-471-08705-2); Vovk et al. (2005, ISBN:978-0-387-25061-8); Nakagawa and de Villemereuil (2019) <doi:10.1093/sysbio/syy089>.

An R-Shiny application implementing a method of sexing the human os coxae based on logistic regressions and Bruzek's nonmetric traits <doi:10.1002/ajpa.23855>.