Estimation and goodness-of-fit functions for copula-based models of bivariate data with arbitrary distributions (discrete, continuous, mixture of both types). The copula families considered here are the Gaussian, Student, Clayton, Frank, Gumbel, Joe, Plackett, BB1, BB6, BB7,BB8, together with the following non-central squared copula families in Nasri (2020) <doi:10.1016/j.spl.2020.108704>: ncs-gaussian, ncs-clayton, ncs-gumbel, ncs-frank, ncs-joe, and ncs-plackett. For theoretical details, see, e.g., Nasri and Remillard (2023) <arXiv:2301.13408>.

Evaluation of the Carlson elliptic integrals and the incomplete elliptic integrals with complex arguments. The implementations use Carlson's algorithms <doi:10.1007/BF02198293>. Applications of elliptic integrals include probability distributions, geometry, physics, mechanics, electrodynamics, statistical mechanics, astronomy, geodesy, geodesics on conics, and magnetic field calculations.

Solving the problem of project management using CPM (Critical Path Method), PERT (Program Evaluation and Review Technique) and LESS (Least Cost Estimating and Scheduling) methods. The package sets the critical path, schedule and Gantt chart. In addition, it allows to draw a graph even with marked critical activities. For more information about project management see: Taha H. A. "Operations Research. An Introduction" (2017, ISBN:978-1-292-16554-7), Rama Murthy P. "Operations Research" (2007, ISBN:978-81-224-2944-2), Yuval Cohen & Arik Sadeh (2006) "A New Approach for Constructing and Generating AOA Networks", Journal of Engineering, Computing and Architecture 1. 1-13, Konarzewska I., Jewczak M., Kucharski A. (2020, ISBN:978-83-8220-112-3), MiszczyÅ ska D., MiszczyÅ ski M. "Wybrane metody badaÅ operacyjnych" (2000, ISBN:83-907712-0-9).

Routines doing cone projection and quadratic programming, as well as doing estimation and inference for constrained parametric regression and shape-restricted regression problems. See Mary C. Meyer (2013)<doi:10.1080/03610918.2012.659820> for more details.

This package implements a new method ClussCluster descried in Ge Jiang and Jun Li, "Simultaneous Detection of Clusters and Cluster-Specific Genes in High-throughput Transcriptome Data" (Unpublished). Simultaneously perform clustering analysis and signature gene selection on high-dimensional transcriptome data sets. To do so, ClussCluster incorporates a Lasso-type regularization penalty term to the objective function of K- means so that cell-type-specific signature genes can be identified while clustering the cells.

Connect to the California Irrigation Management Information System (CIMIS) Web API. See the CIMIS main page <https://cimis.water.ca.gov> and web API documentation <https://et.water.ca.gov> for more information.

The design of this package allows us to run different clustering packages and compare the results between them, to determine which algorithm behaves best from the data provided. See Martos, L.A.P., Garcà a-Vico, à .M., González, P. et al.(2023) <doi:10.1007/s13748-022-00294-2> "Clustering: an R library to facilitate the analysis and comparison of cluster algorithms.", Martos, L.A.P., Garcà a-Vico, à .M., González, P. et al. "A Multiclustering Evolutionary Hyperrectangle-Based Algorithm" <doi:10.1007/s44196-023-00341-3> and L.A.P., Garcà a-Vico, à .M., González, P. et al. "An Evolutionary Fuzzy System for Multiclustering in Data Streaming" <doi:10.1016/j.procs.2023.12.058>.

This package provides a set of radiative transfer models to quantitatively describe the absorption, reflectance and transmission of solar energy in vegetation, and model remotely sensed spectral signatures of vegetation at distinct spatial scales (leaf,canopy and stand). The main principle behind ccrtm is that many radiative transfer models can form a coupled chain, basically models that feed into each other in a linked chain (from leaf, to canopy, to stand, to atmosphere). It allows the simulation of spectral datasets in the solar spectrum (400-2500nm) using leaf models as PROSPECT5, 5b, and D which can be coupled with canopy models as FLIM', SAIL and SAIL2'. Currently, only a simple atmospheric model ('skyl') is implemented. Jacquemoud et al 2008 provide the most comprehensive overview of these models <doi:10.1016/j.rse.2008.01.026>.

Fits convolution-based nonstationary Gaussian process models to point-referenced spatial data. The nonstationary covariance function allows the user to specify the underlying correlation structure and which spatial dependence parameters should be allowed to vary over space: the anisotropy, nugget variance, and process variance. The parameters are estimated via maximum likelihood, using a local likelihood approach. Also provided are functions to fit stationary spatial models for comparison, calculate the Kriging predictor and standard errors, and create various plots to visualize nonstationarity.

This package provides tools for producing climate-health indicators and supporting official statistics from health and climate data. Implements analytical workflows for temperature-related mortality, wildfire smoke exposure, air pollution, suicides related to extreme heat, malaria, and diarrhoeal disease outcomes, with utilities for descriptive statistics, model validation, attributable fraction and attributable number estimation, relative risk estimation, minimum mortality temperature estimation, and plotting for reporting. These six indicators are endorsed by the United Nations Statistical Commission for inclusion in the Global Set of Environment and Climate Change Statistics. Implemented methods include distributed lag non-linear models (DLNM), quasi-Poisson time-series regression, case-crossover analysis, Bayesian spatio-temporal models using the Integrated Nested Laplace Approximation ('INLA'), and multivariate meta-analysis for sub-national estimates. The package is based on methods developed in the Standards for Official Statistics on Climate-Health Interactions (SOSCHI) project <https://climate-health.officialstatistics.org>. For methodologies, see Watkins et al. (2026) <doi:10.5281/zenodo.14865904>, Jose et al. (2026) <doi:10.5281/zenodo.14052183>, Pearce et al. (2026) <doi:10.5281/zenodo.14050224>, Byukusenge et al. (2026) <doi:10.5281/zenodo.15585042>, Dzakpa et al. (2026) <doi:10.5281/zenodo.14881886>, and Dzakpa et al. (2026) <doi:10.5281/zenodo.14871506>.

This package provides a systematic biology tool was developed to identify cell infiltration via Individualized Cell-Cell interaction network. CITMIC first constructed a weighted cell interaction network through integrating Cell-target interaction information, molecular function data from Gene Ontology (GO) database and gene transcriptomic data in specific sample, and then, it used a network propagation algorithm on the network to identify cell infiltration for the sample. Ultimately, cell infiltration in the patient dataset was obtained by normalizing the centrality scores of the cells.

Tests, utilities, and case studies for analyzing significance in clustered binary matched-pair data. The central function clust.bin.pair uses one of several tests to calculate a Chi-square statistic. Implemented are the tests Eliasziw (1991) <doi:10.1002/sim.4780101211>, Obuchowski (1998) <doi:10.1002/(SICI)1097-0258(19980715)17:13%3C1495::AID-SIM863%3E3.0.CO;2-I>, Durkalski (2003) <doi:10.1002/sim.1438>, and Yang (2010) <doi:10.1002/bimj.201000035> with McNemar (1947) <doi:10.1007/BF02295996> included for comparison. The utility functions nested.to.contingency and paired.to.contingency convert data between various useful formats. Thyroids and psychiatry are the canonical datasets from Obuchowski and Petryshen (1989) <doi:10.1016/0165-1781(89)90196-0> respectively.

Genome-wide association studies (GWAS) have been widely used for identifying common variants associated with complex diseases. Due to the small effect sizes of common variants, the power to detect individual risk variants is generally low. Complementary to SNP-level analysis, a variety of gene-based association tests have been proposed. However, the power of existing gene-based tests is often dependent on the underlying genetic models, and it is not known a priori which test is optimal. Here we proposed COMBined Association Test (COMBAT) to incorporate strengths from multiple existing gene-based tests, including VEGAS, GATES and simpleM. Compared to individual tests, COMBAT shows higher overall performance and robustness across a wide range of genetic models. The algorithm behind this method is described in Wang et al (2017) <doi:10.1534/genetics.117.300257>.

Conducts conditional random sampling on observed values in sparse matrices. Useful for training and test set splitting sparse matrices prior to model fitting in cross-validation procedures and estimating the predictive accuracy of data imputation methods, such as matrix factorization or singular value decomposition (SVD). Although designed for applications with sparse matrices, CRASSMAT can also be applied to complete matrices, as well as to those containing missing values.

This package provides a minimum set of functions to perform compositional data analysis using the log-ratio approach introduced by John Aitchison (1982). Main functions have been implemented in c++ for better performance.

This package provides a collection of tools for designing, implementing, testing, documenting and visualizing dynamic simulation cropping system models. Models are specified as a combination of state variables, parameters, intermediate factors and input data that define a system of ordinary differential equations. Specified models can be used to simulate dynamic processes using numerical integration algorithms.

Deduplicates bibliographic citations from multiple sources while preserving customizable metadata, supporting data-driven search strategy development and evidence synthesis reporting. Search results can be analyzed using plots and tables, and imported or exported in RIS and CSV formats. An interactive shiny application is included for exploratory use.

This package provides a common misconception is that the Hochberg procedure comes up with adequate overall type I error control when test statistics are positively correlated. However, unless the test statistics follow some standard distributions, the Hochberg procedure requires a more stringent positive dependence assumption, beyond mere positive correlation, to ensure valid overall type I error control. To fill this gap, we formulate statistical tests grounded in rank correlation coefficients to validate fulfillment of the positive dependence through stochastic ordering (PDS) condition. See Gou, J., Wu, K. and Chen, O. Y. (2024). Rank correlation coefficient based tests on positive dependence through stochastic ordering with application in cancer studies, Technical Report.

This package implements the iterated RMCD method of Cerioli (2010) for multivariate outlier detection via robust Mahalanobis distances. Also provides the finite-sample RMCD method discussed in the paper, as well as the methods provided in Hardin and Rocke (2005) <doi:10.1198/106186005X77685> and Green and Martin (2017) <https://christopherggreen.github.io/papers/hr05_extension.pdf>. See also Chapter 2 of Green (2017) <https://digital.lib.washington.edu/researchworks/handle/1773/40304>.

Core visualizations and summaries for the CRAN package database. The package provides comprehensive methods for cleaning up and organizing the information in the CRAN package database, for building package directives networks (depends, imports, suggests, enhances, linking to) and collaboration networks, producing package dependence trees, and for computing useful summaries and producing interactive visualizations from the resulting networks and summaries. The resulting networks can be coerced to igraph <https://CRAN.R-project.org/package=igraph> objects for further analyses and modelling.

Discover causality for bivariate categorical data. This package aims to enable users to discover causality for bivariate observational categorical data. See Ni, Y. (2022) <arXiv:2209.08579> "Bivariate Causal Discovery for Categorical Data via Classification with Optimal Label Permutation. Advances in Neural Information Processing Systems 35 (in press)".

Clustering method to cluster both effects curves, through quantile regression coefficient modeling, and curves in functional data analysis. Sottile G. and Adelfio G. (2019) <doi:10.1007/s00180-018-0817-8>.

This package provides a comprehensive high-level package, for composite indicator construction and analysis. It is a "development environment" for composite indicators and scoreboards, which includes utilities for construction (indicator selection, denomination, imputation, data treatment, normalisation, weighting and aggregation) and analysis (multivariate analysis, correlation plotting, short cuts for principal component analysis, global sensitivity analysis, and more). A composite indicator is completely encapsulated inside a single hierarchical list called a "coin". This allows a fast and efficient work flow, as well as making quick copies, testing methodological variations and making comparisons. It also includes many plotting options, both statistical (scatter plots, distribution plots) as well as for presenting results.

Allows inferring gene regulatory networks with direct physical interactions from microarray expression data using C3NET.