Construction and analysis of matrix population models in R.

Probability generating function, formulae for the probabilities (discrete density) and random generation for discrete stable random variables.

Phase I/II adaptive dose-finding design for combination studies where toxicity rates are supposed to increase with both agents.

The disparity filter algorithm is a network reduction technique to identify the backbone structure of a weighted network without destroying its multi-scale nature. The algorithm is documented in M. Angeles Serrano, Marian Boguna and Alessandro Vespignani in "Extracting the multiscale backbone of complex weighted networks", Proceedings of the National Academy of Sciences 106 (16), 2009. This implementation of the algorithm supports both directed and undirected networks.

Model cell type heterogeneity of bulk renal cell carcinoma. The observed gene expression in bulk tumor sample is modeled by a log-normal distribution with the location parameter structured as a linear combination of the component-specific gene expressions.

Analyze and visualize the rhythmic behavior of animals using the degree of functional coupling (See Scheibe (1999) <doi:10.1076/brhm.30.2.216.1420>), compute and visualize harmonic power, actograms, average activity and diurnality index.

Estimates dose-response relations from summarized dose-response data and to combines them according to principles of (multivariate) random-effects models.

Functionality for manipulating values of associative maps. The package is a dependency for mvp-type packages that use the STL map class: it traps plausible idiom that is ill-defined (implementation-specific) and returns an informative error, rather than returning a possibly incorrect result. To cite the package in publications please use Hankin (2022) <doi:10.48550/ARXIV.2210.03856>.

Distribution (S4-)classes for elliptically contoured distributions (based on package distr').

This package implements an efficient algorithm for solving sparse-penalized support vector machines with kernel density convolution. This package is designed for high-dimensional classification tasks, supporting lasso (L1) and elastic-net penalties for sparse feature selection and providing options for tuning kernel bandwidth and penalty weights. The dcsvm is applicable to fields such as bioinformatics, image analysis, and text classification, where high-dimensional data commonly arise. Learn more about the methodology and algorithm at Wang, Zhou, Gu, and Zou (2023) <doi:10.1109/TIT.2022.3222767>.

This package provides a R driver for Apache Drill<https://drill.apache.org>, which could connect to the Apache Drill cluster<https://drill.apache.org/docs/installing-drill-on-the-cluster> or drillbit<https://drill.apache.org/docs/embedded-mode-prerequisites> and get result(in data frame) from the SQL query and check the current configuration status. This link <https://drill.apache.org/docs> contains more information about Apache Drill.

This package provides a common interface for applying dimensionality reduction methods, such as Principal Component Analysis ('PCA'), Independent Component Analysis ('ICA'), diffusion maps, Locally-Linear Embedding ('LLE'), t-distributed Stochastic Neighbor Embedding ('t-SNE'), and Uniform Manifold Approximation and Projection ('UMAP'). Has built-in support for sparse matrices.

Load configuration from a .env file, that is in the current working directory, into environment variables.

This package provides a collection of functions to search and download Digital Surface Model (DSM) and Light Detection and Ranging (LiDAR) data via APIs, including OpenTopography <https://portal.opentopography.org/apidocs/> and TNMAccess <https://apps.nationalmap.gov/tnmaccess/#/>, and canopy tree height data.

This package provides functions for fitting Cox proportional hazards models for grouped time-to-event data, where the shared group-specific frailties have a discrete nonparametric distribution. The methods proposed in the package is described by Gasperoni, F., Ieva, F., Paganoni, A. M., Jackson, C. H., Sharples, L. (2018) <doi:10.1093/biostatistics/kxy071>. There are also functions for simulating from these models, with a nonparametric or a parametric baseline hazard function.

The assay sensitivity is the minimum number of copies that the digital PCR assay can detect. Users provide serial dilution results in the format of counts of positive and total reaction wells. The output is the estimated assay sensitivity and the copy number per well in the initial dilute.

Direction analysis is a set of tools designed to identify combinatorial effects of multiple treatments/conditions on pathways and kinases profiled by microarray, RNA-seq, proteomics, or phosphoproteomics data. See Yang P et al (2014) <doi:10.1093/bioinformatics/btt616>; and Yang P et al. (2016) <doi:10.1002/pmic.201600068>.

Allows to visualize high-density electroencephalography (HD-EEG) data through interactive plots and animations, enabling exploratory and communicative analysis of temporal-spatial brain signals. Funder: Masaryk University (Grant No. MUNI/A/1457/2023).

Supporting the quantitative analysis of binary welfare based decision making processes using Monte Carlo simulations. Decision support is given on two levels: (i) The actual decision level is to choose between two alternatives under probabilistic uncertainty. This package calculates the optimal decision based on maximizing expected welfare. (ii) The meta decision level is to allocate resources to reduce the uncertainty in the underlying decision problem, i.e to increase the current information to improve the actual decision making process. This problem is dealt with using the Value of Information Analysis. The Expected Value of Information for arbitrary prospective estimates can be calculated as well as Individual Expected Value of Perfect Information. The probabilistic calculations are done via Monte Carlo simulations. This Monte Carlo functionality can be used on its own.

Estimate and return the needed parameters for visualizations designed for OpenBudgets.eu <http://openbudgets.eu/> datasets. Calculate descriptive statistical measures in budget data of municipalities across Europe, according to the OpenBudgets.eu data model. There are functions for measuring central tendency and dispersion of amount variables along with their distributions and correlations and the frequencies of categorical variables for a given dataset. Also, can be used generally to other datasets, to extract visualization parameters, convert them to JSON format and use them as input in a different graphical interface.

This package provides R bindings to the dockview JavaScript library <https://dockview.dev/>. Create fully customizable grid layouts (docks) in seconds to include in interactive R reports with R Markdown or Quarto or in shiny apps <https://shiny.posit.co/>. In shiny mode, modify docks by dynamically adding, removing or moving panels or groups of panels from the server function. Choose among 8 stunning themes (dark and light), serialise the state of a dock to restore it later.

Efficient covariate-adjusted estimators of quantities that are useful for establishing the effects of treatments on ordinal outcomes.

This package provides functions to download, process, and visualize German geospatial data across administrative levels, including states, districts, and municipalities. Supports interactive tables and customized maps using built-in or external datasets. Official shapefiles are accessed from the German Federal Agency for Cartography and Geodesy (BKG) <https://gdz.bkg.bund.de/>, licensed under dl-de/by-2-0 <https://www.govdata.de/dl-de/by-2-0>.

The state-of-the-art algorithms for distance metric learning, including global and local methods such as Relevant Component Analysis, Discriminative Component Analysis, Local Fisher Discriminant Analysis, etc. These distance metric learning methods are widely applied in feature extraction, dimensionality reduction, clustering, classification, information retrieval, and computer vision problems.