This package provides a system designed for detecting concept drift in streaming datasets. It offers a comprehensive suite of statistical methods to detect concept drift, including methods for monitoring changes in data distributions over time. The package supports several tests, such as Drift Detection Method (DDM), Early Drift Detection Method (EDDM), Hoeffding Drift Detection Methods (HDDM_A, HDDM_W), Kolmogorov-Smirnov test-based Windowing (KSWIN), Adaptive WINdowing (ADWIN) and Page Hinkley (PH) tests. The methods implemented in this package are based on established research and have been demonstrated to be effective in real-time data analysis. For more details on the methods, please check to the following sources. KobyliÅ ska et al. (2023) <doi:10.48550/arXiv.2308.11446>, S. Kullback & R.A. Leibler (1951) <doi:10.1214/aoms/1177729694>, Gama et al. (2004) <doi:10.1007/978-3-540-28645-5_29>, Baena-Garcia et al. (2006) <https://www.researchgate.net/publication/245999704_Early_Drift_Detection_Method>, Frà as-Blanco et al. (2014) <https://ieeexplore.ieee.org/document/6871418>, Bifet and Gavalda (2007) <doi:10.1137/1.9781611972771>, Raab et al. (2020) <doi:10.1016/j.neucom.2019.11.111>, Page (1954) <doi:10.1093/biomet/41.1-2.100>, Montiel et al. (2018) <https://jmlr.org/papers/volume19/18-251/18-251.pdf>.

This package provides a simple way of fitting detection functions to distance sampling data for both line and point transects. Adjustment term selection, left and right truncation as well as monotonicity constraints and binning are supported. Abundance and density estimates can also be calculated (via a Horvitz-Thompson-like estimator) if survey area information is provided. See Miller et al. (2019) <doi:10.18637/jss.v089.i01> for more information on methods and <https://distancesampling.org/resources/vignettes.html> for example analyses.

Cluster-randomized trials (CRTs) assign treatment to groups rather than individuals, so valid analyses must distinguish cluster-level and individual-level effects and define estimands within a potential-outcomes framework. This package supports right-censored survival outcomes for both single-state (binary) and multi-state settings. For single-state outcomes, it provides estimands based on stage-specific survival contrasts (SPCE) and restricted mean survival time (RMST). For multi-state outcomes, it provides SPCE as well as a generalized win-based restricted mean time-in-favor estimand (RMT-IF). The package implements doubly robust estimators that accommodate covariate-dependent censoring and remain consistent if either the outcome model or the censoring model is correctly specified. Users can choose marginal Cox or gamma-frailty Cox working models for nuisance estimation, and inference is supported via leave-one-cluster-out jackknife variance and confidence interval estimation. Methods are described in Fang et al. (2025) "Estimands and doubly robust estimation for cluster-randomized trials with survival outcomes" <doi:10.48550/arXiv.2510.08438>.

This package provides a novel framework for detecting, quantifying, and analyzing dormant patterns in multivariate data. Dormant patterns are statistical relationships that exist in data but remain inactive until specific trigger conditions emerge. This concept, inspired by biological dormancy (seeds, pathogens) and geological phenomena (dormant faults), provides tools to identify latent risks, hidden correlations, and potential phase transitions in complex systems. The package introduces methods for quantifying dormancy depth, trigger sensitivity, and awakening risk - enabling analysts to discover patterns that conventional methods miss because they focus only on currently active relationships.

This package provides a convenient API interface to access immunological data within the CAVD DataSpace'(<https://dataspace.cavd.org>), a data sharing and discovery tool that facilitates exploration of HIV immunological data from pre-clinical and clinical HIV vaccine studies.

Create quick and easy dot-and-whisker plots of regression results. It takes as input either (1) a coefficient table in standard form or (2) one (or a list of) fitted model objects (of any type that has methods implemented in the parameters package). It returns ggplot objects that can be further customized using tools from the ggplot2 package. The package also includes helper functions for tasks such as rescaling coefficients or relabeling predictor variables. See more methodological discussion of the visualization and data management methods used in this package in Kastellec and Leoni (2007) <doi:10.1017/S1537592707072209> and Gelman (2008) <doi:10.1002/sim.3107>.

Learning and inference over dynamic Bayesian networks of arbitrary Markovian order. Extends some of the functionality offered by the bnlearn package to learn the networks from data and perform exact inference. It offers three structure learning algorithms for dynamic Bayesian networks: Trabelsi G. (2013) <doi:10.1007/978-3-642-41398-8_34>, Santos F.P. and Maciel C.D. (2014) <doi:10.1109/BRC.2014.6880957>, Quesada D., Bielza C. and Larrañaga P. (2021) <doi:10.1007/978-3-030-86271-8_14>. It also offers the possibility to perform forecasts of arbitrary length. A tool for visualizing the structure of the net is also provided via the visNetwork package. Further detailed information and examples can be found in our Journal of Statistical Software paper Quesada D., Larrañaga P. and Bielza C. (2025) <doi:10.18637/jss.v115.i06>.

This package provides a wrapper for the ZEIT ONLINE Content API, available at <http://developer.zeit.de>. diezeit gives access to articles and corresponding metadata from the ZEIT archive and from ZEIT ONLINE. A personal API key is required for usage.

Infer progression of circadian rhythms in transcriptome data in which samples are not labeled with time of day and coverage of the circadian cycle may be incomplete. See Shilts et al. (2018) <doi:10.7717/peerj.4327>.

This package provides functions for demographic analysis including lifetable calculations; Lee-Carter modelling; functional data analysis of mortality rates, fertility rates, net migration numbers; and stochastic population forecasting.

Decomposing value added growth into explanatory factors. A cost constrained value added function is defined to specify the production frontier. Industry estimates can also be aggregated using a weighted average approach. Details about the methodology and data can be found in Diewert and Fox (2018) <doi:10.1093/oxfordhb/9780190226718.013.19> and Zeng, Parsons, Diewert and Fox (2018) <https://www.business.unsw.edu.au/research-site/centreforappliedeconomicresearch-site/Documents/emg2018-6_SZeng_EMG-Slides.pdf>.

Area under the curve (AUC; Myerson et al., 2001) <doi:10.1901/jeab.2001.76-235> is a popular measure used in discounting research. Although the calculation of AUC is standardized, there are differences in AUC based on some assumptions. For example, Myerson et al. (2001) <doi:10.1901/jeab.2001.76-235> assumed that (with delay discounting data) a researcher would impute an indifference point at zero delay equal to the value of the larger, later outcome. However, this practice is not clearly followed. This imputed zero-delay indifference point plays an important role in log and ordinal versions of AUC. Ordinal and log versions of AUC are described by Borges et al. (2016)<doi:10.1002/jeab.219>. The package can calculate all three versions of AUC [and includes a new version: IHS(AUC)], impute indifference points when x = 0, calculate ordinal AUC in the case of Halton sampling of x-values, and account for probability discounting AUC.

This package provides functions for the calculation and plotting of synchrony in tree growth from tree-ring width chronologies (TRW index). It combines variance-covariance (VCOV) mixed modelling with functions that quantify the degree to which the TRW chronologies contain a common temporal signal. It also implements temporal trends in spatial synchrony using a moving window. These methods can also be used with other kind of ecological variables that have temporal autocorrelation corrected.

This package provides a Bayesian clustering method for replicated time series or replicated measurements from multiple experimental conditions, e.g., time-course gene expression data. It estimates the number of clusters directly from the data using a Dirichlet-process prior. See Fu, A. Q., Russell, S., Bray, S. and Tavare, S. (2013) Bayesian clustering of replicated time-course gene expression data with weak signals. The Annals of Applied Statistics. 7(3) 1334-1361. <doi:10.1214/13-AOAS650>.

This package provides statistical tools for analyzing net and relative survival, with a key feature of relaxing the assumption of independent censoring and incorporating the effect of dependent competing risks. It employs a copula-based methodology, specifically the Archimedean copula, to simulate data, conduct survival analysis, and offer comparisons with other methods. This approach is detailed in the work of Adatorwovor et al. (2022) <doi:10.1515/ijb-2021-0016>.

Flexible and efficient cleaning of data with interactivity. datacleanr facilitates best practices in data analyses and reproducibility with built-in features and by translating interactive/manual operations to code. The package is designed for interoperability, and so seamlessly fits into reproducible analyses pipelines in R'.

This package provides tools to help the design and analysis of resilient non-inferiority trials. These include functions for sample size calculations and analyses of trials, with either a risk difference, risk ratio or arc-sine difference margin, and a function to run simulations to design a trial with the methods described in Quartagno et al. (2019) <arXiv:1905.00241>.

Seasonal- and calendar adjustment of time series with daily frequency using the DSA approach developed by Ollech, Daniel (2018): Seasonal adjustment of daily time series. Bundesbank Discussion Paper 41/2018.

Bayesian Beta Regression, adapted for bounded discrete responses, commonly seen in survey responses. Estimation is done via Markov Chain Monte Carlo sampling, using a Gibbs wrapper around univariate slice sampler (Neal (2003) <DOI:10.1214/aos/1056562461>), as implemented in the R package MfUSampler (Mahani and Sharabiani (2017) <DOI: 10.18637/jss.v078.c01>).

Similarity of dissolution profiles is assessed using the similarity factor f2 according to the EMA guideline (European Medicines Agency 2010) "On the investigation of bioequivalence". Dissolution profiles are regarded as similar if the f2 value is between 50 and 100. For the applicability of the similarity factor f2, the variability between profiles needs to be within certain limits. Often, this constraint is violated. One possibility in this situation is to resample the measured profiles in order to obtain a bootstrap estimate of f2 (Shah et al. (1998) <doi:10.1023/A:1011976615750>). Other alternatives are the model-independent non-parametric multivariate confidence region (MCR) procedure (Tsong et al. (1996) <doi:10.1177/009286159603000427>) or the T2-test for equivalence procedure (Hoffelder (2016) <https://www.ecv.de/suse_item.php?suseId=Z|pi|8430>). Functions for estimation of f1, f2, bootstrap f2, MCR / T2-test for equivalence procedure are implemented.

Discriminant Analysis (DA) for evolutionary inference (Qin, X. et al, 2020, <doi:10.22541/au.159256808.83862168>), especially for population genetic structure and community structure inference. This package incorporates the commonly used linear and non-linear, local and global supervised learning approaches (discriminant analysis), including Linear Discriminant Analysis of Kernel Principal Components (LDAKPC), Local (Fisher) Linear Discriminant Analysis (LFDA), Local (Fisher) Discriminant Analysis of Kernel Principal Components (LFDAKPC) and Kernel Local (Fisher) Discriminant Analysis (KLFDA). These discriminant analyses can be used to do ecological and evolutionary inference, including demography inference, species identification, and population/community structure inference.

Model estimation, dispersion testing and diagnosis of hyper-Poisson Saez-Castillo, A.J. and Conde-Sanchez, A. (2013) <doi:10.1016/j.csda.2012.12.009> and Conway-Maxwell-Poisson Huang, A. (2017) regression models.

Fit a mixture of Discrete Laplace distributions using plain numerical optimisation. This package has similar applications as the disclapmix package that uses an EM algorithm.

Basic time series functionalities such as listing of missing values, application of arbitrary aggregation as well as rolling (asymmetric) window functions and automatic detection of periodicity. As it is mainly based on data.table', it is fast and (in combination with the R6 package) offers reference semantics. In addition to its native R6 interface, it provides an S3 interface for those who prefer the latter. Finally yet importantly, its functional approach allows for incorporating functionalities from many other packages.