Includes functions for interacting with common meta data fields, writing insert statements, calling functions, and more for T-SQL and Postgresql'.

Data sets used by Krause et al. (2022) <doi:10.1101/2022.04.11.487885>. It comprises phenotypic records obtained from the USDA Northern Region Uniform Soybean Tests from 1989 to 2019 for maturity groups II and III. In addition, soil and weather variables are provided for the 591 observed environments (combination of locations and years).

We present a rank-based Mercer kernel to compute a pair-wise similarity metric corresponding to informative representation of data. We tailor the development of a kernel to encode our prior knowledge about the data distribution over a probability space. The philosophical concept behind our construction is that objects whose feature values fall on the extreme of that featureâ s probability mass distribution are more similar to each other, than objects whose feature values lie closer to the mean. Semblance emphasizes features whose values lie far away from the mean of their probability distribution. The kernel relies on properties empirically determined from the data and does not assume an underlying distribution. The use of feature ranks on a probability space ensures that Semblance is computational efficacious, robust to outliers, and statistically stable, thus making it widely applicable algorithm for pattern analysis. The output from the kernel is a square, symmetric matrix that gives proximity values between pairs of observations.

Code and data for modelling and simulation of stochastic kinetic biochemical network models. It contains the code and data associated with the second and third editions of the book Stochastic Modelling for Systems Biology, published by Chapman & Hall/CRC Press.

Simple and flexible quizzes in shiny'. Easily create quizzes from various pre-built question and choice types or create your own using htmltools and shiny packages as building blocks. Integrates with larger shiny applications. Ideal for non-web-developers such as educators, data scientists, and anyone who wants to assess responses interactively in a small form factor.

This package provides an R interface to SymEngine <https://github.com/symengine/>, a standalone C++ library for fast symbolic manipulation. The package has functionalities for symbolic computation like calculating exact mathematical expressions, solving systems of linear equations and code generation.

An interface to access data from Substack publications via API. Users can fetch the latest, top, search for specific posts, or retrieve a single post by its slug. This functionality is useful for developers and researchers looking to analyze Substack content or integrate it into their applications. For more information, visit the API documentation at <https://substackapi.dev/introduction>.

This package provides functions for reading and writing Gadget N-body snapshots. The Gadget code is popular in astronomy for running N-body / hydrodynamical cosmological and merger simulations. To find out more about Gadget see the main distribution page at www.mpa-garching.mpg.de/gadget/.

SCEPtER pipeline for estimating the stellar age for double-lined detached binary systems. The observational constraints adopted in the recovery are the effective temperature, the metallicity [Fe/H], the mass, and the radius of the two stars. The results are obtained adopting a maximum likelihood technique over a grid of pre-computed stellar models.

We integrated the common analysis methods utilized in single cell RNA sequencing data, which included cluster method, principal components analysis (PCA), the filter of differentially expressed genes, pathway enrichment analysis and correlated analysis methods.

Stop signal task data of go and stop trials is generated per participant. The simulation process is based on the generally non-independent horse race model and fixed stop signal delay or tracking method. Each of go and stop process is assumed having exponentially modified Gaussian(ExG) or Shifted Wald (SW) distributions. The output data can be converted to BEESTS software input data enabling researchers to test and evaluate various brain stopping processes manifested by ExG or SW distributional parameters of interest. Methods are described in: Soltanifar M (2020) <https://hdl.handle.net/1807/101208>, Matzke D, Love J, Wiecki TV, Brown SD, Logan GD and Wagenmakers E-J (2013) <doi:10.3389/fpsyg.2013.00918>, Logan GD, Van Zandt T, Verbruggen F, Wagenmakers EJ. (2014) <doi:10.1037/a0035230>.

Data and functions to support Bayesian and frequentist inference and decision making for the Coursera Specialization "Statistics with R". See <https://github.com/StatsWithR/statsr> for more information.

This package provides tools for interacting with U.S. Geological Survey ScienceBase <https://www.sciencebase.gov> interfaces. ScienceBase is a data cataloging and collaborative data management platform. Functions included for querying ScienceBase, and creating and fetching datasets.

This package provides a supervised compression method that incorporates the response for reducing big data to a carefully selected subset. Please see Joseph and Mak (2021) <doi:10.1002/sam.11508>. This research is supported by a U.S. National Science Foundation (NSF) grant CMMI-1921646.

This package provides tools for sample survey planning, including sample size calculation, estimation of expected precision for the estimates of totals, and calculation of optimal sample size allocation.

Easily create pretty popup messages (modals) in Shiny'. A modal can contain text, images, OK/Cancel buttons, an input to get a response from the user, and many more customizable options.

This package performs mutational signature analysis for targeted sequenced tumors. Unlike the canonical analysis of mutational signatures, SATS factorizes the mutation counts matrix into a panel context matrix (measuring the size of the targeted sequenced genome for each tumor in the unit of million base pairs (Mb)), a signature profile matrix, and a signature activity matrix. SATS also calculates the expected number of mutations attributed by a signature, namely signature burden, for each targeted sequenced tumor. For more details see Lee et al. (2024) <doi:10.1101/2023.05.18.23290188>.

Consolidated data simulation, sample size calculation and analysis functions for several snSMART (small sample sequential, multiple assignment, randomized trial) designs under one library. See Wei, B., Braun, T.M., Tamura, R.N. and Kidwell, K.M. "A Bayesian analysis of small n sequential multiple assignment randomized trials (snSMARTs)." (2018) Statistics in medicine, 37(26), pp.3723-3732 <doi:10.1002/sim.7900>.

Efficient implementations for Sorted L-One Penalized Estimation (SLOPE): generalized linear models regularized with the sorted L1-norm (Bogdan et al. 2015). Supported models include ordinary least-squares regression, binomial regression, multinomial regression, and Poisson regression. Both dense and sparse predictor matrices are supported. In addition, the package features predictor screening rules that enable fast and efficient solutions to high-dimensional problems.

Linkage disequilibrium visualizations of up to several hundreds of single nucleotide polymorphisms (SNPs), annotated with chromosomic positions and gene names. Two types of plots are available for small numbers of SNPs (<40) and for large numbers (tested up to 500). Both can be extended by combining other ggplots, e.g. association studies results, and functions enable to directly visualize the effect of SNP selection methods, as minor allele frequency filtering and TagSNP selection, with a second correlation heatmap. The SNPs correlations are computed on Genotype Data objects from the GWASTools package using the SNPRelate package, and the plots are customizable ggplot2 and gtable objects and are annotated using the biomaRt package. Usage is detailed in the vignette with example data and results from up to 500 SNPs of 1,200 scans are in Charlon T. (2019) <doi:10.13097/archive-ouverte/unige:161795>.

Makes it possible to serve map tiles for web maps (e.g. leaflet) based on a function or a stars object without having to render them in advance. This enables parallelization of the rendering, separating the data source and visualization location and to provide web services.

This is a core implementation of SAS procedures for linear models - GLM, REG, ANOVA, TTEST, FREQ, and UNIVARIATE. Some R packages provide type II and type III SS. However, the results of nested and complex designs are often different from those of SAS. Different results does not necessarily mean incorrectness. However, many wants the same results to SAS. This package aims to achieve that. Reference: Littell RC, Stroup WW, Freund RJ (2002, ISBN:0-471-22174-0).

Health research using data from electronic health records (EHR) has gained popularity, but misclassification of EHR-derived disease status and lack of representativeness of the study sample can result in substantial bias in effect estimates and can impact power and type I error for association tests. Here, the assumed target of inference is the relationship between binary disease status and predictors modeled using a logistic regression model. SAMBA implements several methods for obtaining bias-corrected point estimates along with valid standard errors as proposed in Beesley and Mukherjee (2020) <doi:10.1101/2019.12.26.19015859>, currently under review.

This package provides a dynamic timer control (DTC) is a shiny widget that enables time-based processes in applications. It allows users to execute these processes manually in individual steps or at customizable speeds. The timer can be paused, resumed, or restarted. This control is particularly well-suited for simulations, animations, countdowns, or interactive visualizations.