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This package provides robust model-based clustering using a t-mixture model with Box-Cox transformation.
This package contains several tools for analyzing Sanger Sequencing data files in R, including reading .scf and .ab1 files, making basecalls and plotting chromatograms.
This package contains default datasets used by the Bioconductor package biscuiteer.
This package contains whole-genome single cell sequencing data for demonstration purposes in the AneuFinder package.
This package provides RangedSummarizedExperiment objects of read counts in genes and exonic parts for paired-end RNA-Seq data from experiments on primary cultures of parathyroid tumors. The sequencing was performed on tumor cultures from 4 patients at 2 time points over 3 conditions (DPN, OHT and control).
This package provides summarized MinION sequencing data for Salmonella Typhi published by Ashton et al. in 2015. Three replicate runs are each provided as Fast5Summary objects.
This package is developed for the analysis and visualization of clonal tracking data. The required data is formed by samples and tag abundances in matrix form, usually from cellular barcoding experiments, integration site retrieval analyses, or similar technologies.
MultiBaC is a strategy to correct batch effects from multiomic datasets distributed across different labs or data acquisition events. MultiBaC is able to remove batch effects across different omics generated within separate batches provided that at least one common omic data type is included in all the batches considered.
systemPipeRdata complements the systemPipeR workflow management system (WMS) by offering a collection of pre-designed data analysis workflow templates. These templates are easily accessible and can be readily loaded onto a user's system with a single command. Once loaded, the WMS can immediately utilize these templates for efficient end-to-end analysis, serving a wide range of data analysis needs.
The package contains functions that can be used to compare expression measures for Affymetrix Oligonucleotide Arrays.
This package provides a parser for mzIdentML files implemented using the XML package. The parser tries to be general and able to handle all types of mzIdentML files with the drawback of having less pretty output than a vendor specific parser.
The goal of sansSouci is to perform post hoc inference: in a multiple testing context, sansSouci provides statistical guarantees on possibly user-defined and/or data-driven sets of hypotheses.
BAnOCC is a package designed for compositional data, where each sample sums to one. It infers the approximate covariance of the unconstrained data using a Bayesian model coded with rstan. It provides as output the stanfit object as well as posterior median and credible interval estimates for each correlation element.
This package provides an R interface to Illumina's BaseSpace cloud computing environment, enabling the fast development of data analysis and visualization tools. Besides providing an easy to use set of tools for manipulating the data from BaseSpace, it also facilitates the access to R's rich environment of statistical and data analysis tools.
This package is used for the identification and validation of sequence motifs. It makes use of STAMP for comparing a set of motifs to a given database (e.g. JASPAR). It can also be used to visualize motifs, motif distributions, modules and filter motifs.
The atSNP package performs affinity tests of motif matches with the SNP (single nucleotide polymorphism) or the reference genomes and SNP-led changes in motif matches.
This package contains example data for Illumina microarray output files, for testing purposes.
The atena package quantifies expression of TEs (transposable elements) from RNA-seq data through different methods, including ERVmap, TEtranscripts and Telescope. A common interface is provided to use each of these methods, which consists of building a parameter object, calling the quantification function with this object and getting a SummarizedExperiment object as an output container of the quantified expression profiles. The implementation allows quantifing TEs and gene transcripts in an integrated manner.
This package provides a subset of BAM files untreated1.bam (single-end reads) and untreated3.bam (paired-end reads) from "Pasilla" experiment (Pasilla knock-down by Brooks et al., Genome Research 2011). See the vignette in the pasilla data package for how BAM files untreated1.bam and untreated3.bam were obtained from the RNA-Seq read sequence data that is provided by NCBI Gene Expression Omnibus under accession numbers GSM461176 to GSM461181. It also contains the DNA sequence for fly chromosome 4 to which the reads can be mapped.
This package provides a set of annotation maps describing the entire Human Disease Ontology. The annotation data comes from https://github.com/DiseaseOntology/HumanDiseaseOntology/tree/main/src/ontology.
This package provides Ion Trap positive ionization mode data in mzML file format. It includes a subset from 500-850 m/z and 1190-1310 seconds, including MS2 and MS3, intensity threshold 100.000; extracts from FTICR Apex III, m/z 400-450; a subset of UPLC - Bruker micrOTOFq data, both mzML and mz5; LC-MSMS and MRM files from proteomics experiments; and PSI mzIdentML example files for various search engines.
This package provides a flexible representation of copy number, mutation, and other data that fit into the ragged array schema for genomic location data. The basic representation of such data provides a rectangular flat table interface to the user with range information in the rows and samples/specimen in the columns. The RaggedExperiment class derives from a GRangesList representation and provides a semblance of a rectangular dataset.
This is a package for the automated analysis of Affymetrix arrays. It provides reporting features.
This package contains classes used in model-view-controller (MVC) design.