This package provides an implementation of a rare variant association test that utilizes protein tertiary structure to increase signal and to identify likely causal variants. Performs structure-guided collapsing, which leads to local tests that borrow information from neighboring variants on a protein and that provide association information on a variant-specific level. For details of the implemented method see West, R. M., Lu, W., Rotroff, D. M., Kuenemann, M., Chang, S-M., Wagner M. J., Buse, J. B., Motsinger-Reif, A., Fourches, D., and Tzeng, J-Y. (2019) <doi:10.1371/journal.pcbi.1006722>.

Gene-level variant association tests with disease status for pedigree data: kernel and burden association statistics.

Uses provenance collected by rdtLite package or comparable tool to display information about input files, output files, and exchanged files for a single R script or a series of R scripts.

Calibrate p-values under a robust perspective using the methods developed by Sellke, Bayarri, and Berger (2001) <doi:10.1198/000313001300339950> and obtain measures of the evidence provided by the data in favor of point null hypotheses which are safer and more straightforward to interpret.

This package provides a function kitten() which creates cute little packages which pass R package checks. This sets it apart from package.skeleton() which it calls, and which leaves imperfect files behind. As this is not exactly helpful for beginners, kitten() offers an alternative. Unit test support can be added via the tinytest package (if present), and documentation-creation support can be added via roxygen2 (if present).

This package provides functions for computing fit indices for evaluating the path component of latent variable structural equation models. Available fit indices include RMSEA-P and NSCI-P originally presented and evaluated by Williams and O'Boyle (2011) <doi:10.1177/1094428110391472> and demonstrated by O'Boyle and Williams (2011) <doi:10.1037/a0020539> and Williams, O'Boyle, & Yu (2020) <doi:10.1177/1094428117736137>. Also included are fit indices described by Hancock and Mueller (2011) <doi:10.1177/0013164410384856>.

Given a SpatialPolygonsDataFrame and a set of populations for each polygon, compute a population density estimate based on Tobler's pycnophylactic interpolation algorithm. The result is a SpatialGridDataFrame. Methods are described in Tobler Waldo R. (1979) <doi:10.1080/01621459.1979.10481647>.

Evaluate the predictive performance of an existing (i.e. previously developed) prediction/ prognostic model given relevant information about the existing prediction model (e.g. coefficients) and a new dataset. Provides a range of model updating methods that help tailor the existing model to the new dataset; see Su et al. (2018) <doi:10.1177/0962280215626466>. Techniques to aggregate multiple existing prediction models on the new data are also provided; see Debray et al. (2014) <doi:10.1002/sim.6080> and Martin et al. (2018) <doi:10.1002/sim.7586>).

Estimation of panel models for glm-like models: this includes binomial models (logit and probit), count models (poisson and negbin) and ordered models (logit and probit), as described in: Baltagi (2013) Econometric Analysis of Panel Data, ISBN-13:978-1-118-67232-7, Hsiao (2014) Analysis of Panel Data <doi:10.1017/CBO9781139839327> and Croissant and Millo (2018), Panel Data Econometrics with R, ISBN:978-1-118-94918-4.

Density, distribution function, quantile function and random generation for the family of power and reversal power distributions.

Automates the process of creating a scale bar and north arrow in any package that uses base graphics to plot in R. Bounding box tools help find and manipulate extents. Finally, there is a function to automate the process of setting margins, plotting the map, scale bar, and north arrow, and resetting graphic parameters upon completion.

Provision of a set of models and methods for use in the allocation and management of capital in financial portfolios.

This package provides tools for the practical management of financial portfolios: backtesting investment and trading strategies, computing profit/loss and returns, analysing trades, handling lists of transactions, reporting, and more. The package provides a small set of reliable, efficient and convenient tools for processing and analysing trade/portfolio data. The manual provides all the details; it is available from <https://enricoschumann.net/R/packages/PMwR/manual/PMwR.html>. Examples and descriptions of new features are provided at <https://enricoschumann.net/notes/PMwR/>.

This package implements principal component analysis, orthogonal rotation and multiple factor analysis for a mixture of quantitative and qualitative variables.

This package provides a collection of R functions that are widely used by the Petersen Lab. Included are functions for various purposes, including evaluating the accuracy of judgments and predictions, performing scoring of assessments, generating correlation matrices, conversion of data between various types, data management, psychometric evaluation, extensions related to latent variable modeling, various plotting capabilities, and other miscellaneous useful functions. By making the package available, we hope to make our methods reproducible and replicable by others and to help others perform their data processing and analysis methods more easily and efficiently. The codebase is provided in Petersen (2025) <doi:10.5281/zenodo.7602890> and on CRAN': <doi: 10.32614/CRAN.package.petersenlab>. The package is described in "Principles of Psychological Assessment: With Applied Examples in R" (Petersen, 2024, 2025a) <doi:10.1201/9781003357421>, <doi:10.25820/work.007199>, <doi:10.5281/zenodo.6466589> and in "Fantasy Football Analytics: Statistics, Prediction, and Empiricism Using R" (Petersen, 2025b).

Currently incorporate the generalized odds-rate model (a type of linear transformation model) for interval-censored data based on penalized monotonic B-Spline. More methods under other semiparametric models such as cure model or additive model will be included in future versions. For more details see Lu, M., Liu, Y., Li, C. and Sun, J. (2019) <arXiv:1912.11703>.

Allows the comparison of data cohorts (DC) against a Counter Factual Model (CFM) and measures the difference in terms of an efficacy parameter. Allows the application of Personalised Synthetic Controls.

Fits right-truncated meta-analysis (RTMA), a bias correction for the joint effects of p-hacking (i.e., manipulation of results within studies to obtain significant, positive estimates) and traditional publication bias (i.e., the selective publication of studies with significant, positive results) in meta-analyses [see Mathur MB (2022). "Sensitivity analysis for p-hacking in meta-analyses." <doi:10.31219/osf.io/ezjsx>.]. Unlike publication bias alone, p-hacking that favors significant, positive results (termed "affirmative") can distort the distribution of affirmative results. To bias-correct results from affirmative studies would require strong assumptions on the exact nature of p-hacking. In contrast, joint p-hacking and publication bias do not distort the distribution of published nonaffirmative results when there is stringent p-hacking (e.g., investigators who hack always eventually obtain an affirmative result) or when there is stringent publication bias (e.g., nonaffirmative results from hacked studies are never published). This means that any published nonaffirmative results are from unhacked studies. Under these assumptions, RTMA involves analyzing only the published nonaffirmative results to essentially impute the full underlying distribution of all results prior to selection due to p-hacking and/or publication bias. The package also provides diagnostic plots described in Mathur (2022).

An interactive document for preprocessing the dataset using rmarkdown and shiny packages. Runtime examples are provided in the package function as well as at <https://analyticmodels.shinyapps.io/PREPShiny/>.

This package provides functions for the computation of F-, f- and D-statistics (e.g., Fst, hierarchical F-statistics, Patterson's F2, F3, F3*, F4 and D parameters) in population genomics studies from allele count or Pool-Seq read count data and for the fitting, building and visualization of admixture graphs. The package also includes several utilities to manipulate Pool-Seq data stored in standard format (e.g., such as vcf files or rsync files generated by the the PoPoolation software) and perform conversion to alternative format (as used in the BayPass and SelEstim software). As of version 2.0, the package also includes utilities to manipulate standard allele count data (e.g., stored in TreeMix', BayPass and SelEstim format, see the Package vignette for details).

Creation of patient profile visualizations for exploration, diagnostic or monitoring purposes during a clinical trial. These static visualizations display a patient-specific overview of the evolution during the trial time frame of parameters of interest (as laboratory, ECG, vital signs), presence of adverse events, exposure to a treatment; associated with metadata patient information, as demography, concomitant medication. The visualizations can be tailored for specific domain(s) or endpoint(s) of interest. Visualizations are exported into patient profile report(s) or can be embedded in custom report(s).

This extension of the poems pattern-oriented modeling (POM) framework provides a collection of modules and functions customized for paleontological time-scales, and optimized for single-generation transitions and large populations, across multiple generations.

This package provides a tidyverse'-style interface to the Brazilian Central Bank (<https://www.bcb.gov.br>) PIX Open Data API <https://olinda.bcb.gov.br/olinda/servico/Pix_DadosAbertos/versao/v1/aplicacao#!/recursos>. Retrieve statistics on PIX keys, transactions by municipality, and monthly transaction summaries. All functions return tibbles and support OData query parameters for filtering, selecting, and ordering data.

Simulating particle movement in 2D space has many application. The particles package implements a particle simulator based on the ideas behind the d3-force JavaScript library. particles implements all forces defined in d3-force as well as others such as vector fields, traps, and attractors.