This package provides tools for calculating and viewing topological properties of phylogenetic trees.

Density, distribution function, quantile function, and random generation function based on Kittipong Klinjan,Tipat Sottiwan and Sirinapa Aryuyuen (2024)<DOI:10.28919/cmbn/8833>.

This package provides function for performing Bayesian survival regression using Horseshoe prior in the accelerated failure time model with log normal assumption in order to achieve high dimensional pan-cancer variable selection as developed in Maity et. al. (2019) <doi:10.1111/biom.13132>.

Estimate specification models for the state-dependent level of an optimal quantile/expectile forecast. Wald Tests and the test of overidentifying restrictions are implemented. Plotting of the estimated specification model is possible. The package contains two data sets with forecasts and realizations: the daily accumulated precipitation at London, UK from the high-resolution model of the European Centre for Medium-Range Weather Forecasts (ECMWF, <https://www.ecmwf.int/>) and GDP growth Greenbook data by the US Federal Reserve. See Schmidt, Katzfuss and Gneiting (2015) <arXiv:1506.01917> for more details on the identification and estimation of a directive behind a point forecast.

Given a SpatialPolygonsDataFrame and a set of populations for each polygon, compute a population density estimate based on Tobler's pycnophylactic interpolation algorithm. The result is a SpatialGridDataFrame. Methods are described in Tobler Waldo R. (1979) <doi:10.1080/01621459.1979.10481647>.

Levels and changes of productivity and profitability are measured with various indices. The package contains the multiplicatively complete Färe-Primont, Fisher, Hicks-Moorsteen, Laspeyres, Lowe, and Paasche indices, as well as the classic Malmquist productivity index. Färe-Primont and Lowe indices verify the transitivity property and can therefore be used for multilateral or multitemporal comparison. Fisher, Hicks-Moorsteen, Laspeyres, Malmquist, and Paasche indices are not transitive and are only to be used for binary comparison. All indices can also be decomposed into different components, providing insightful information on the sources of productivity and profitability changes. In the use of Malmquist productivity index, the technological change index can be further decomposed into bias technological change components. The package also allows to prohibit technological regression (negative technological change). In the case of the Fisher, Hicks-Moorsteen, Laspeyres, Paasche and the transitive Färe-Primont and Lowe indices, it is furthermore possible to rule out technological change. Deflated shadow prices can also be obtained. Besides, the package allows parallel computing as an option, depending on the user's computer configuration. All computations are carried out with the nonparametric Data Envelopment Analysis (DEA), and several assumptions regarding returns to scale are available. All DEA linear programs are implemented using lp_solve'.

Design parameters of the optimal two-period multiarm platform design (controlling for either family-wise error rate or pair-wise error rate) can be calculated using this package, allowing pre-planned deferred arms to be added during the trial. More details about the design method can be found in the paper: Pan, H., Yuan, X. and Ye, J. (2022) "An optimal two-period multiarm platform design with new experimental arms added during the trial". Manuscript submitted for publication. For additional references: Dunnett, C. W. (1955) <doi:10.2307/2281208>.

This package provides tools for the evaluation of interim analysis plans for sequentially monitored trials on a survival endpoint; tools to construct efficacy and futility boundaries, for deriving power of a sequential design at a specified alternative, template for evaluating the performance of candidate plans at a set of time varying alternatives. See Izmirlian, G. (2014) <doi:10.4310/SII.2014.v7.n1.a4>.

Computes the exact probability density function of X/Y conditioned on positive quadrant for series of bivariate distributions,for more details see Nadarajah,Song and Si (2019) <DOI:10.1080/03610926.2019.1576893>.

This package provides a unified method, called M statistic, is provided for detecting phylogenetic signals in continuous traits, discrete traits, and multi-trait combinations. Blomberg and Garland (2002) <doi:10.1046/j.1420-9101.2002.00472.x> provided a widely accepted statistical definition of the phylogenetic signal, which is the "tendency for related species to resemble each other more than they resemble species drawn at random from the tree". The M statistic strictly adheres to the definition of phylogenetic signal, formulating an index and developing a method of testing in strict accordance with the definition, instead of relying on correlation analysis or evolutionary models. The novel method equivalently expressed the textual definition of the phylogenetic signal as an inequality equation of the phylogenetic and trait distances and constructed the M statistic. Also, there are more distance-based methods under development.

Assessment for statistically-based PPQ sampling plan, including calculating the passing probability, optimizing the baseline and high performance cutoff points, visualizing the PPQ plan and power dynamically. The analytical idea is based on the simulation methods from the textbook Burdick, R. K., LeBlond, D. J., Pfahler, L. B., Quiroz, J., Sidor, L., Vukovinsky, K., & Zhang, L. (2017). Statistical Methods for CMC Applications. In Statistical Applications for Chemistry, Manufacturing and Controls (CMC) in the Pharmaceutical Industry (pp. 227-250). Springer, Cham.

Identifies differences between versions of a package. Specifically, the functions help determine if there are breaking changes from one package version to the next. The package also includes a stability assessment, to help you determine the overall stability of a package, or even an entire repository.

This package provides a dataset of Pokemon information in both English and Brazilian Portuguese. The dataset contains 949 rows and 22 columns, including information such as the Pokemon's name, ID, height, weight, stats, type, and more.

Allows the user to perform ANOVA tests (in a strict sense: continuous and normally-distributed Y variable and 1 or more factorial/categorical X variable(s)), with the possibility to specify the type of sum of squares (1, 2 or 3), the types of variables (Fixed or Random) and their relationships (crossed or nested) with the sole function of the package (FullyParamANOVA()). The resulting outputs are the same as in SAS software. A dataset (Butterfly) to test the function is also joined.

This package provides functions to perform Bayesian inference on absorption time data for Phase-type distributions. The methods of Bladt et al (2003) <doi:10.1080/03461230110106435> and Aslett (2012) <https://www.louisaslett.com/PhD_Thesis.pdf> are provided.

Useful for preparing and cleaning data. It includes functions to center data, reverse coding, dummy code and effect code data, and more.

Simulate and run the Gaussian puff forward atmospheric model in sensor (specific sensor coordinates) or grid (across the grid of a full oil and gas operations site) modes, following Jia, M., Fish, R., Daniels, W., Sprinkle, B. and Hammerling, D. (2024) <doi:10.26434/chemrxiv-2023-hc95q-v3>. Numerous visualization options, including static and animated, 2D and 3D, and a site map generator based on sensor and source coordinates.

This package provides tools for estimating model-agnostic prediction intervals using conformal prediction, bootstrapping, and parametric prediction intervals. The package is designed for ease of use, offering intuitive functions for both binned and full conformal prediction methods, as well as parametric interval estimation with diagnostic checks. Currently only working for continuous predictions. For details on the conformal and bin-conditional conformal prediction methods, see Randahl, Williams, and Hegre (2024) <DOI:10.48550/arXiv.2410.14507>.

Data sets for statistical inference modeling related to People Analytics. Contains various data sets from the book Handbook of Regression Modeling in People Analytics by Keith McNulty (2020).

Conduct internal validation of a clinical prediction model for a binary outcome. Produce bias corrected performance metrics (c-statistic, Brier score, calibration intercept/slope) via bootstrap (simple bootstrap, bootstrap optimism, .632 optimism) and cross-validation (CV optimism, CV average). Also includes functions to assess model stability via bootstrap resampling. See Steyerberg et al. (2001) <doi:10.1016/s0895-4356(01)00341-9>; Harrell (2015) <doi:10.1007/978-3-319-19425-7>; Riley and Collins (2023) <doi:10.1002/bimj.202200302>.

Perform a differential analysis at pathway level based on metabolite quantifications and information on pathway metabolite composition. The method, described in Guilmineau et al (2025) <doi:10.1186/s12859-025-06118-z> is based on a Principal Component Analysis step and on a linear mixed model. Automatic query of metabolic pathways is also implemented.

Create random passwords of letters, numbers and punctuation.

This package provides a unified and user-friendly framework for applying the principal sufficient dimension reduction methods for both linear and nonlinear cases. The package has an extendable power by varying loss functions for the support vector machine, even for an user-defined arbitrary function, unless those are convex and differentiable everywhere over the support (Li et al. (2011) <doi:10.1214/11-AOS932>). Also, it provides a real-time sufficient dimension reduction update procedure using the principal least squares support vector machine (Artemiou et al. (2021) <doi:10.1016/j.patcog.2020.107768>).

This package provides functions are primarily functions for systems of ordinary differential equations, difference equations, and eigenanalysis and projection of demographic matrices; data are for examples.